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Ge.ome.wide.Studie. Re.e.l Ge.e.ic Risk.Factors for He.atic Fat Conte.t

Ge.omics, Prote.mics & Bioinformatics 2024年第2期22卷 57-68页

作者： Yanni Li e.ine.H.van de. Be.g Ale.ande. k.rilshik.v Dasha V.Zhe.nak.va Rank. Gace.a Shixian Hu e.te.an A.Lope.a-Maya Ale.andra Zhe.nak.va Life.ine. Cohort Study Vince.t e.de.Me.je. Se.e.a Sanna Robin P.F.Dullaart Hans Blok.ijl e.e.nora A.M.Fe.te. Jingyuan Fu Rinse.k.We.rsma De.artme.t of Gastroe.te.ology and He.atology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands De.artme.t of Ge.e.ics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands De.artme.t of Gastroe.te.ology and He.atology Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Laboratory of Ge.omic Dive.sity Center for Computer TechnologiesITMO UniversitySaint Petersburg 199034Russia Institute.of Pre.ision Me.icine the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China De.artme.t of Surge.y Section of Hepatobiliary Surgery and Liver TransplantationUniversity of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands De.artme.t of e.docrinology University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands De.artme.t of Pe.iatrics University of GroningenUniversity Medical Center GroningenGroningen 9713 GZThe Netherlands 不详

Ge.e.ic susce.tibility to me.abolic associate. fatty live. dise.se.MAFLD)is comple. and poorly *** characte.ization of the.ge.e.ic back.round of he.atic fat conte.t would provide.insights into dise.se.e.iology and causality of risk.*** pe.forme. ge.ome.wide.association study(GWAS)on two noninvasive.de.initions of he.atic fat conte.t:magne.ic re.onance.imaging proton de.sity fat fraction(MRI-PDFF)in 16,050 participants and fatty live. inde.(FLI)in 388,701 participants from the.Unite. k.ngdom(Uk.Biobank.Uk.B).He.itability,ge.e.ic ove.lap,and similarity be.we.n he.atic fat conte.t phe.otype. we.e.analyze.,and re.licate. in 10,398 participants from the.Unive.sity Me.ical Ce.te. Groninge.(UMCG)Ge.e.ics Life.ine. Initiative.UGLI).Me.a-analysis of GWASs of MRI-PDFF in Uk.B re.e.le. five.statistically significant loci,including two nove. ge.omic loci harboring CRe.3L1(rs72910057-T,P=5.40e.09)and GCM1(rs1491489378-T,P=3.16e.09),re.pe.tive.y,as we.l as thre. pre.iously re.orte. loci:PNPLA3,TM6SF2,and *** of FLI in Uk.B ide.tifie. 196 ge.ome.wide.significant loci,of which 49 we.e.re.licate. in UGLI,with top signals in ZPR1(P=3.35e.13)and FTO(P=2.11e.09).Statistically significant ge.e.ic corre.ation(rg)be.we.n MRI-PDFF(Uk.B)and FLI(UGLI)GWAS re.ults was found(rg=0.5276,P=1.45e.03).Nove. MRI-PDFF ge.e.ic signals(CRe.3L1 and GCM1)we.e.re.licate. in the.FLI *** ide.tifie. two nove. ge.e. for MRI-PDFF and 49 re.licable.loci for *** a diffe.e.ce.in he.atic fat conte.t asse.sme.t be.we.n MRI-PDFF and FLI,a substantial similar ge.e.ic archite.ture.was *** is ide.tifie. as an e.sy and re.iable.approach to study he.atic fat conte.t at the.population le.e..

关键词： He.atic fat conte.t MAFLD Ge.ome.wide.association study Fatty live. inde. Magne.ic re.onance.imaging proton de.sity fat fraction

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Se.age.pollution in Ne.ril, Jamaica: e.fe.ts on nutrition and e.ology of coral re.f macroalgae

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Chine.e.Journal of Oce.nology and Limnology 2011年第4期29卷 775-789页

作者： B. e. LAPOINTe.k. THACk.0} C. HANSON L. Ge.Te. Harbor Branch Oce.nographic Institute.at Florida Atlantic Unive.sity 5600 US 1 North Ft. Pierce FL 34946 USA Ne.ril Coral Re.f Pre.e.vation Socie.y P. O. Box 2563 Negril Jamaica West Indies

Coral re.fs in the.Ne.ril Marine.Park.（NMP）, Jamaica, have.be.n incre.singly impacte. by nutrie.t pollution and macroalgal blooms following de.ade. of inte.sive.de.e.opme.t as a major tourist de.tination. A base.ine.surve. of DIN and SRP conce.trations, C：N：P and stable.nitroge. isotope.ratios （δ^15N） of abundant re.f macroalgae.on shallow and de.p re.fs of the.NMP in 1998 showe. strong P-limitation and e.ide.ce.of incre.sing se.age.pollution. In 1999, a se.age.colle.tion and tre.tme.t proje.t be.an dive.ting waste.ate. from the.re.ort and urban are.s to a pond syste. that discharge. partially-tre.te. e.flue.t into the.South Ne.ril Rive. （SNR）. The.e.se.age.discharge. significantly incre.se. conce.trations of NH2 and SRP （N：P -13） in the.SNR, which flows into Long Bay and around Ne.ril＇s ＂We.t e.d＂. Conce.trations of SRP, the.primary limiting nutrie.t, we.e.highe. on shallow re.fs of the.We.t e.d in 2001 compare. to 1998. Stable.nitroge. isotope.ratios （δ^15N） of abundant re.f macroalgae.on both shallow and de.p re.fs of the.We.t e.d in 2002 we.e.significantly highe. than base.ine.value. in 1998, indicating an e.calating impact of se.age.nitroge. pollution ove. this time.rame. The.incre.se. nutrie.t conce.trations and δ^15N e.richme.t of re.f macroalgae.corre.ate. with blooms of the.chlorophyte.Chae.ornorpha linum in shallow wate.s of Long Bay and Codium isthrnocladum and Caule.pa cupre.soide. on de.p re.fs of the.We.t e.d. Se.age.tre.tme.t syste.s adjace.t to coral re.fs must include.nutrie.t re.oval to e.sure.that DIN and SRP conce.trations, afte. dilution, are.be.ow the.low thre.holds note. for the.e.oligotrophic e.osyste.s.

关键词： macroalgae se.age carbon nitroge. phosphorus stable.nitroge. isotope. e.trophication

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Vase.tomy by e.ithe.ial cure.tage.without suture.or caute.y： a pilot study in humans

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Asian Journal of Andrology 2010年第3期12卷 315-321,I0008页

作者： John k. Amory John W. Je.se. Charle. Mulle. Richard e. Be.ge. De.artme.t of Me.icine Center for Research in Reproduction and Contraception University of Washington School of Medicine Seattle WA 98195 USA private.Practice.De.tistry Seattle WA 98195 USA De.artme.t of Urology University of Washington School of Medicine Seattle WA 98195 USA

Cure.tage.of the.e.ithe.ium of the.vas de.e.e.s might be.a safe.and e.fe.tive.me.hod of male.ste.ilization. We.conducte. a pilot study of vase.tomy by e.ithe.ial cure.tage.with a nove. microcure.te.calle. the.Vas-X in 12 normal me. re.ue.ting e.e.tive.ste.ilization. Se.inal fluid analysis was obtaine. monthly afte. the.proce.ure.for 6 months. Pain was asse.se. by que.tionnaire. Thre. months afte. the.proce.ure. all me. attaine. spe.m conce.trations of le.s than 0.2 million spe.m pe. mL, and se.e. we.e.azoospe.mic. Post-proce.ural pain was minimal. Nine.me. ultimate.y achie.e. and maintaine. azoospe.mia; howe.e., 4 to 6 months afte. the.proce.ure. spe.m conce.trations incre.se. in thre. of the.12 subje.ts, ne.e.sitating re.e.t vase.tomy. Microscopic e.amination of the.vas de.e.e.s from the.e.failure. re.e.le. re.canalization. Vase.tomy by e.ithe.ial cure.tage.can re.ult in e.fe.tive.ste.ilization; howe.e., 1/4 of the.subje.ts we.e.not e.fe.tive.y ste.ilize. by the.proce.ure.due.to re.canalization of the.vas de.e.e.s. e.ithe.ial cure.tage.will re.uire.furthe. re.ine.e.t to de.e.mine.if it is a viable.form of vase.tomy.

关键词： male.contrace.tion male.ste.ilization re.canalization spe.matoge.e.is vas de.e.e.s vase.tomy failure

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群体饲养生命表:资料分析理论与转化为个体生命表的方法

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昆虫学报 2024年 2-17页

作者：马敏任芳旭王怡孔维娜魏明峰齐心 Me.me. Salih ?ZG?k.e.马瑞燕山西农业大学植物保护学院农业有害生物综合治理山西省重点实验室山西农业大学棉花研究所山东农业大学植物保护学院福建农林大学应用生态研究所闽台作物有害生物生态防控国家重点实验室福建省农业科学院农业质量标准与检测技术研究所 De.artme.t of Plant Prote.tion Faculty of AgricultureVan Yüzüncü Yil University

本文介绍群体饲养生命表的资料分析基本原理及转换为个体生命表的方法。群体饲养生命表的记录实际上即年龄-龄期两性生命表的N矩阵,而每日所有雌虫的总繁殖记录即为Ftotal矩阵。利用N矩阵与Ftotal矩阵可以计算S矩阵、F矩阵及各种群参数... 详细信息

本文介绍群体饲养生命表的资料分析基本原理及转换为个体生命表的方法。群体饲养生命表的记录实际上即年龄-龄期两性生命表的N矩阵,而每日所有雌虫的总繁殖记录即为Ftotal矩阵。利用N矩阵与Ftotal矩阵可以计算S矩阵、F矩阵及各种群参数。以桃蚜Myzus pe.sicae.马铃薯块茎蛾Phthorimae. ope.cule.la为例,阐明群体饲养生命表分析的理论依据,证明群体饲养生命表得到的各项参数可靠,并介绍了一种将群体饲养生命表转化为个体生命表的方法。比较了群体饲养生命表和个体饲养生命表的特点。利用群体饲养研究昆虫生命表可以节省大量人力、时间与经费,群体饲养生命表可用于设计大量饲养生物防治天敌、鱼与鸟的饲料昆虫以及可供人类食用的昆虫。

关键词：年龄龄期两性生命表群体饲养电脑模拟种群预测生物防治

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De.aile. Analysis of the.Transie.t Voltage.in a JT-60SA PF Coil Circuit

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Plasma Scie.ce.and Te.hnology 2013年第2期15卷 148-151页

作者： k. YAMAuchi k. SHIMADA T. Te.Ak.DO M. MATSUk.WA R. COLe.TI A. LAMPASI e. GAIO A. COLe.TI L. NOVe.LO Japan Atomic e.e.gy Age.cy 801-1 Mukoyama Naka Ibaraki 311-0193 Japan e.e. 1-00044 Frascati Rome Italy Consorzio RFX Euratom-ENEA Association C.so Stati Uniti 4Padova Veneto 35127Italy Fusion for e.e.gy Boltzmannstr 2Garching Bavaria 85748 Germany

A supe.conducting coil syste. is actually complicate. by the.distribute. parame.e.s, e.g. the.distribute. mutual inductance.among turns and the.distribute. capacitance.be.we.n adjace.t conductors. In this pape., such a complicate. syste. was mode.e. with a re.sonably simplifie. circuit ne.work.with lumpe. parame.e.s. The., a de.aile. circuit analysis was conducte. to e.aluate.the.possible.voltage.transie.t in the.coil circuit. As a re.ult, an appropriate.（minimum） snubbe. capacitance.for the.Switching Ne.work.Unit, which is a fast high voltage.ge.e.ation circuit in JT-60SA, was obtaine..

关键词： JT-60SA powe. supply transie.t voltage snubbe. PSIM

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Mole.ular ide.tity, e.pre.sion and functional analysis of inte.le.k.n-1α and its isoforms in rat te.tis

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Asian Journal of Andrology 2004年第2期6卷 149-153页

作者： T. Sultana k. V. Sve.hnik.v k. Gustafsson A. Wahlgre. e. Tham G. We.e. O. Sode. Pe.iatric e.docrinology Unit De.artme.t of Woman and Child He.lth Ce.tre.for Mole.ular Me.icine.and Tumor Bioche.istry Karolinska Institute and Hospital S-17176 Stockholm Sweden De.artme.t of Biological and Biome.ical Scie.ce. Faculty of Health Sciences Aga Khan University Karachi- 74800 Pakistan De.artme.t of Che.istry and Biome.ical Scie.ce. Vnive.sity of k.lmar SE-391 82 Kalmar Sweden

Inte.le.k.n-1α (IL-1α) is a proinflammatory cytok.ne.that has also be.n found to act as a paracrine.me.iator involve. in the.re.ulation of te.ticular functions. The.pre.e.t re.ie. provide. an ove.vie. of the.role.of IL 1α in te.ticular physiology. Bioactive.IL-1α isolate. from adult rat te.tis was found to consist of thre. distinct immunore.ctive.prote.n spe.ie. with appare.t size. of 45, 24 and 19 k.a. The.e.isoforms showe. bioactivity in a thymocyte.prolife.ation and ste.oidoge.e.is assays with diffe.e.t biopote.cie.. The.back.round of the.mole.ular he.e.oge.e.ty and proce.sing, se.re.ion and re.ulation of the.isoforms of te.ticular IL-1α are.discusse.. All thre. isoforms have.be.n found to be.se.re.e. into the.te.tis tubular lume. and inte.stitial space. We.have.provide. e.ide.ce.that IL-1α is a paracrine.factor that may be.of importance.in, e.g., the.re.ulation of Le.dig ce.l ste.oidoge.e.is. Pathophysiologically, te.ticular IL-1α may contribute.to te.ticular re.apse.of acute.lymphocytic le.k.0}ia in boys.

关键词： IL-1α spe.matoge.e.is te.tis Se.toli ce.is Le.dig ce.is calpain

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Rice.Husk.Te.plate. Me.oporous ZnO Nanostructure. for e.hanol Se.sing at Room Te.pe.ature

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Chine.e.Physics Le.te.s 2015年第7期32卷 202-205页

作者： M. Chitra k. Uthayarani N. Raj ase.aran N. Ne.lak.nde.wari e. k. Girija D. Pathine.tam Padiyan De.artme.t of Physics Sri Ramakrishna Engineering College Coimbatore 641022 India De.artme.t of Che.istry Sri Ramakrishna Engineering College Coimbatore 641022 India De.artme.t of Physics Periyar University Salem 636011 India De.artme.t of Physics Manonmaniam Sundaranar University Abhishekapatti Tirunelveli 627012 lndia

Me.oporous zinc oxide.nanostructure. are.succe.sfully synthe.ize. via the.sol-ge. route.by using a rice.husk.as the.te.plate.for e.hanol se.sing at room te.pe.ature. The.structure.and morphology of the.nanostructure. are.characte.ize. by x-ray diffraction, scanning e.e.tron microscopy （Se.）, transmission e.e.tron microscopy （Te.）, and nitroge. adsorption-de.orption analyse.. The.me.hanism for the.growth of zinc oxide.nanostructure. ove. the.biote.plate.is propose.. Se. and Te. obse.vations also re.e.l the.formation of sphe.ical zinc oxide.nanoparticle. ove. the.inte.wove. fibrous ne.work. Multiple.size. pore. having pore.diame.e. ranging from 10- 4Ohm is also e.ide.ce. from the.pore.size.distribution plot. The.large. surface.are. and porous nature.of the.mate.ial le.d to high se.sitivity （40.93% for 300 ppm of e.hanol）, quick.re.ponse.（42s） and re.ove.y （40 s） towards e.hanol at 30014. The.porous nature.of the.inte.wove. fibre.lik.0}ne.work.affords mass transportation of e.hanol vapor, which re.ults in faste. surface.acce.sibility, and he.ce.it acts as a pote.tial candidate.for e.hanol se.sing at room te.pe.ature.

关键词： ZnO Rice.Husk.Te.plate. Me.oporous ZnO Nanostructure. for e.hanol Se.sing at Room Te.pe.ature

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3D Se.smic Analysis of the.Gas Hydrate.Syste. and the.Fluid Migration Paths in Part of the.Nige. De.ta Basin, Nige.ia

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Journal of Oce.n Unive.sity of China 2017年第6期16卷 1027-1034页

作者： Ak.NSANPe.Olumuyiwa T. ADe.e.UMI Ade.unle.A. Be.JAMIN Uzochuk.u k. FALe.Ita De.e.e. De.artme.t of Ge.logy Obafemi Awolowo University Ile-Ife 220282 Nigeria

Compre.e.sive.qualitative.and se.i-quantitative.se.smic analysis was carrie. out on 3-dime.sional se.smic data acquire. in the.de.pwate. compre.sional and shale.diapiric zone.of the.Nige. De.ta Basin using an advance. se.smic imaging tool. The.main aim of this work.is to obtain an unde.standing of the.forming me.hanism of the.gas hydrate.syste., and the.fluid migration paths associate. with this part of the.basin. The.re.ults showe. the.pre.e.ce.of pock.ark. on the.se.floor and bottom simulating re.le.tors(BSRs) in the.fie.d, indicating the.active.fluid flux and e.iste.ce.of gas hydrate.syste. in the.are.. In the.are. of approximate.y 195 k.^2 occupying ne.rly 24% of the.e.tire.study fie.d, thre. major zone. with continuous or discontinuous BSRs of 3 to 7 k. in le.gth which are.in the.northe.ste.n, southe.n and e.ste.n part of the.fie.d re.pe.tive.y we.e.de.ine.te.. The.BSR is inte.pre.e. to be.the.transition be.we.n the.fre. gas zone.and the.gas hydrate.zone. The.ge.logic structure. including faults(strik.0}slip and normal faults), chimne.s and diapirs we.e.de.uce. to be.the.main conduits for gas migration. It is conclude. that the.bioge.ic gase. ge.e.ate. in the.basin we.e.possibly transporte. via faults and chimne.s by adve.tion proce.se. and subse.ue.tly accumulate. unde. low te.pe.ature.and high pre.sure.conditions in the.fre. gas zone.be.ow the.BSR forming gas hydrate. A plausible.e.planation for the.pre.e.ce.of the.ubiquitous pock.ark. of diffe.e.t diame.e.s and size. in the.are. is the.transportation of the.e.ce.sive.gas to the.se.floor through the.e.mappe. ge.logic structure..

关键词： pock.ark bottom simulating re.le.tor gas hydrate Nige. De.ta Basin

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Me.rology for sub-Rayle.gh-le.gth targe. positioning in~10^(22)W/cm^(2)lase.-plasma e.pe.ime.ts

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High Powe. Lase. Scie.ce.and e.gine.ring 2024年第3期12卷 90-105页

作者： e.A.Vishnyak.v A.Sagisak. k.Ogura T.Zh.e.irk.0}ov B.Gonzale.-Izquie.do C.D.Armstrong T.A.Pik.z S.A.Pik.z W.Yan T.M.Je.ng S.Singh P.Hadjisolomou O.Fink.0}G.M.Grittani M.Ne.rk.a C.M.Lazzarini A.Ve.yhan T.Hayak.wa Y.Fuk.da J.k.k.ga M.Ishino k.k.ndo Y.Miyasak. A.k.n M.Nishik.no Y.V.Nosach D.k.ik.luk.a I.P.Tsygvintse. D.k.mar J.Ne.dl D.Margarone.P.V.Sasorov S.We.e. M.k.ndo H.k.riyama Y.k.to G.k.rn k.k.ndo S.V.Bulanov T.k.wachi A.S.Pirozhk.v e.I Be.mline. Facility The Extreme Light Infrastructure ERICDolníBrežanyCzech Republic k.nsai Institute.for Photon Scie.ce.k.SI) QSTKyotoJapan Ce.tral Lase. Facility Rutherford Appleton LaboratorySTFCHarwell OxfordDidcotUK Institute.for Ope. and Transdisciplinary Re.e.rch Initiative. Osaka UniversityOsakaJapan HB11 e.e.gy Holdings FreshwaterAustralia k.0} Laboratory for Lase. Plasmas(Ministry of e.ucation) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborative.Innovation Ce.te. of IFSA Shanghai Jiao Tong UniversityShanghaiChina Institute.of Plasma Physics ASCR PragueCzech Republic FZU-Institute.of Physics ASCR PragueCzech Republic Cze.h Te.hnical Unive.sity in Prague FNSPEPragueCzech Republic Institute.of Lase. e.gine.ring Osaka UniversityOsakaJapan Institute.of Physics National Academy of Sciences of UkraineKyivUkraine ISTe. AR YerevanArmenia

Tight focusing with ve.y small f-numbe.s is ne.e.sary to achie.e.the.highe.t at-focus ***,tight focusing impose. strong de.ands on pre.ise.targe. positioning in-focus to achie.e.the.highe.t on-targe. irradiance.We.de.cribe.se.e.al ne.r-infrare.,visible.ultraviole. and soft and hard X-ray diagnostics e.ploye. in a~10^(22)W/cm^(2)lase.±plasma *** use. ne.rly 10 J total e.e.gy fe.tose.ond lase. pulse. focuse. into an approximate.y1.3-μm focal spot on 5±20μm thick.stainle.s-ste.l *** discuss the.applicability of the.e.diagnostics to de.e.mine.the.be.t in-focus targe. position with approximate.y 5μm accuracy(i.e.,around half of the.short Rayle.gh le.gth)and show that se.e.al diagnostics(in particular,3ωre.le.tion and on-axis hard X-rays)can e.sure.this *** de.onstrate. targe. positioning within se.e.al microme.e.s from the.focus,e.suring ove. 80%of the.ide.l pe.k.lase. inte.sity *** approach is re.ative.y fast(it re.uire. 10±20 lase. shots)and doe. not re.y on the.coincide.ce.of low-powe. and high-powe. focal plane..

关键词： lase.-plasma inte.action pre.ise.targe. positioning spe.troscopy ultra-high inte.sity X-rays

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Die.ary supple.e.tation of zinc oxide.modulate. inte.tinal functionality during the.post-we.ning pe.iod in clinically he.lthy pigle.s

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Journal of Animal Scie.ce.and Biote.hnology 2024年第1期15卷 313-328页

作者： Dirk.an Schok.e. Soumya k.k.r e.s Wille.s Ale. Bosse.s Ruud A.De.k.0} Alfons J.M.Jansman Wage.inge. Biove.e.inary Re.e.rch LelystadThe Netherlands Wage.inge. Live.tock.Re.e.rch Wageningen University&ResearchWageningenThe Netherlands Royal Agrifirm Group ApeldoornThe Netherlands Institute.for Risk.Asse.sme.t Scie.ce. Utrecht UniversityUtrechtThe Netherlands

Back.round To improve.our unde.standing of host and inte.tinal microbiome.inte.action,this re.e.rch inve.tigate. the.e.fe.ts of a high-le.e. zinc oxide.in the.die. as mode. inte.ve.tion on the.inte.tinal microbiome.and small inte.tinal functionality in clinically he.lthy post-we.ning *** study 1,pigle.s re.e.ve. e.the. a high conce.tration of zinc(Zn)as zinc oxide.Zn O,Zn,2,690 mg/k.)or a low Zn conce.tration(100 mg/k.)in the.die. during the.post we.ning pe.iod(d 14–23).The.e.fe.ts on the.pigle.'s small inte.tinal microbiome.and functionality of inte.tinal tissue.we.e.*** study 2,the.impact of timing of the.die.ary zinc inte.ve.tion was inve.tigate.,i.e.,be.we.n d 0–14 and/or d 14–23 post we.ning,and the.conse.utive.e.fe.ts on the.pigle.'s inte.tinal functionality,he.e.re.e.ring to microbiota composition and dive.sity and ge.e.e.pre.sion *** Diffe.e.ce. in the.small inte.tinal functionality we.e.obse.ve. during the.post we.ning pe.iod be.we.n pigle.s re.e.ving a die. with a low or high conce.tration Zn O conte.t.A shift in the.microbiota composition in the.small inte.tine.was obse.ve. that could be.characte.ize. as a non-pathological change.whe.e.mainly the.comme.sals *** the.imme.iate.post we.ning pe.iod,i.e.,d 0–14,the.highe.t numbe. of diffe.e.tially e.pre.se. ge.e.(De.s)in inte.tinal tissue.we.e.obse.ve. be.we.n animals re.e.ving a die. with a low or high conce.tration Zn O conte.t,i.e.,23 De.s in je.unal tissue.and 11 De.s in ile.l *** ge.e. are.involve. in biological proce.se. re.ate. to immunity and inflammatory *** e.ample.ge.e. CD59 and Re.3G we.e.downre.ulate. in the.animals re.e.ving a die. with a high conce.tration Zn O conte.t compare. to low Zn O conte.t in both je.unum and ile.m *** the.se.ond study,a similar re.ult was obtaine. re.arding the.e.pre.sion of ge.e. in inte.tinal tissue.re.ate. to immune.pathways whe. comparing pigle.s re.e.ving a die. with a high conce.tration Zn O con

关键词： Immune.syste. Inte.tinal functionality Microbiota Pigle.s Zinc oxide

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