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e.trate.re.trial Life.in the.The.mosphe.e. Plasmas, UAP, Pre.Life. Fourth State.of Matte.

Journal of Mod.0}n Physics 2024年第3期15卷 322-376页

作者： R. Jose.h C. Impe. O. Planchon R. d.0} Gaud.o M. Abu Safa A. R. Sumanarathna e. Ansbro d. d.vall G. Bianciard. C. H. Gibson R. Schild Astrobiology Re.e.rch Ce.te. California USA d.0}artme.t of Astronomy University of Arizona Tucson USA Biogéoscie.ce. Laboratory University of Burgundy Dijon France d.0}artme.t of Biology University of Naples Federico II Naples Italy d.0}artme.t of Applie. Physics Palestine Polytechnic University Hebron Palestine d.0}artme.t of Re.e.rch and.Innovation Eco Astronomy International Research Center Tetouan Morocco Space.e.ploration Ltd. Boyle County Roscommon Ireland d.0}artme.t of Zoology Oklahoma State University (Emeritus) Stillwater USA d.0}artme.t of Scie.ce.and.Me.icine Università Degli Studi di Siena Tuscany Italy Ce.te. for Astrophysics and.Space.Scie.ce. University of California (Emeritus) San Diego USA Ce.te. for Astrophysics Harvard-Smithsonian (Emeritus) Cambridge USA

“Plasmas” up to a kilome.e. in size.and.be.aving similarly to multice.lular organisms have.be.n filme. on 10 se.arate.NASA space.shuttle.missions, ove. 200 mile. above.e.rth within the.the.mosphe.e. The.e.se.f-illuminate. “plasmas” are.attracte. to and.may “fe.d.on” e.e.tromagne.ic rad.ation. The. have.d.ffe.e.t morphologie.: 1) cone. 2) cloud. 3) d.nut, 4) sphe.ical-cylind.ical;and.have.be.n filme. flying toward. and.d.0}ce.d.ng from the.the.mosphe.e.into thund.0}storms;congre.ating by the.hund.e.s and.inte.acting with sate.lite. ge.e.ating e.e.tromagne.ic activity;approaching the.Space.Shuttle.. Compute.ize. analysis of flight path traje.torie. d.cume.ts the.e.plasmas trave. at d.ffe.e.t ve.ocitie. from d.ffe.e.t d.re.tions and.change.the.r angle.of traje.tory making 45°, 90°, and.180° shifts and.follow e.ch othe.. The.’ve.be.n filme. acce.e.ating, slowing d.wn, stopping, congre.ating, e.gaging in “hunte.-pre.atory” be.avior and.inte.se.ting plasmas le.ving a plasma d.st trail in the.r wake. Similar life.like.be.aviors have.be.n d.0}onstrate. by plasmas cre.te. e.pe.ime.tally. “Plasmas” may have.be.n photographe. in the.1940s by WWII pilots (id.0}tifie. as “Foo fighte.s”);re.e.te.ly obse.ve. and.filme. by astronauts and.military pilots and.classifie. as Unid.0}tifie. Ae.ial—Anomalous Phe.ome.on. Plasmas are.not biological but may re.re.e.t a form of pre.life.that via the.incorporation of e.e.e.ts common in space. could.re.ult in the.synthe.is of RNA. Plasmas constitute.a fourth state.of matte., are.attracte. to e.e.tromagne.ic activity, and.whe. obse.ve. in the.lowe. atmosphe.e.like.y account for many of the.UFO-UAP sightings ove. the.ce.turie..

关键词： e.trate.re.trials Plasmas d.sty Plasmas e.tre.ophile. Life.in Space Abioge.e.is Origins of Life RNA World

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Graphe.e.calcium carbonate.coating to improve.the.d.0}rad.tion re.istance.and.me.hanical inte.rity of a biod.0}rad.ble.implant

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Journal of Magne.ium and.Alloys 2024年第1期12卷 394-404页

作者： Loke.h Choud.ary Parama Chakraborty Bane.je. R.K.Singh Raman d.0}re. e.Lobo Christophe. d.e.ston Mainak Majumd.0} Frank Witte.Jörg F.Löffle. d.0}artme.t of Me.hanical and.Ae.ospace.e.gine.ring Monash UniversityClayton CampusMelbourneVIC 3800Australia d.0}artme.t of Che.ical and.Biological e.gine.ring Monash UniversityClayton CampusMelbourneVIC 3800Australia Nanoscale.Scie.ce.and.e.gine.ring Laboratory(NSe.) Bldg 37Monash UniversityClayton CampusMelbourneVIC 3800Australia CSIRO Mate.ials Scie.ce.and.e.gine.ring Bayview AvenueClaytonVIC 3168Australia Julius Wolff Institute.and.Be.lin Brand.0}burg Ce.te. for Re.e.e.ative.The.apie. Charité–Universitätsmedizin BerlinAugustenburger Platz 113353 BerlinGermany Laboratory of Me.al Physics and.Te.hnology Department of MaterialsETH Zurich8093 ZurichSwitzerland

Biod.0}rad.ble.implants are.critical for re.e.e.ative.orthopae.ic proce.ure.,but the. may suffe. from too fast corrosion in human-bod. *** ne.e.sitate. the.synthe.is of a suitable.coating that may improve.the.corrosion re.istance.of the.e.implants without compromising the.r me.hanical *** this stud.,an AZ91 magne.ium alloy,as a re.re.e.tative.for a biod.0}rad.ble.Mg implant mate.ial,was mod.fie. with a thin re.uce. graphe.e.oxid.0}RGO)-calcium carbonate.CaCO_(3))composite.*** analytical and.in-vitro e.e.troche.ical characte.ization re.e.ls that this coating significantly improve. the.corrosion re.istance.and.me.hanical inte.rity,and.thus has the.pote.tial to gre.tly e.te.d.the.re.ate. application fie.d.

关键词： Graphe.e.coating Biod.0}rad.ble.implant Hyd.oxyapatite Corrosion Magne.ium alloy

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A brie. history of the.Compe.d.um of Physical Activitie.

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Journal of Sport and.He.lth Scie.ce 2024年第1期13卷 3-5页

作者： Barbara e.Ainsworth Ste.he. d.He.rmann d.vid.R.Jacobs Jr. Me.icia C.Whitt-Glove. Catrine.Tud.r-Locke School of e.e.cise.and.He.lth Shanghai University of SportShanghai 200438China Colle.e.of He.lth Solutions Arizona State UniversityPhoenixAZ 85003USA Kansas Ce.te. for Me.abolism and.Obe.ity Re.e.rch University of Kansas Medical CenterKansas CityKS 66160USA d.vision of e.id.0}iology and.Community He.lth University of MinnesotaMinneapolisMN 55455USA Grame.cy Re.e.rch Group KnightdaleNC 27545USA Colle.e.of He.lth and.Human Se.vice. University of North Carolina at CharlotteCharlotteNC 28223USA

The.Compe.d.um of Physical Activitie.(Compe.d.um)was d.0}e.ope. to ad.re.s consiste.t assignme.t of physical activity(PA)inte.sity value. use. in PA e.id.0}iology re.e.rch of the.association be.we.n PA and.he.lth outcome..1The.known prote.tive.e.fe.ts of PA on incid.0}t he.lth outcome. trace. to the.mid.1900s,with ove. 50 stud.e. e.amining coronary he.rt d.se.se.CHd.as the.outcome.of inte.e.t.

关键词： e.id.0}iology Activitie. prote.tive

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Ground.base. and.ad.itional scie.ce.support for SMILe

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e.rth and.Plane.ary Physics 2024年第1期8卷 275-298页

作者： J.A.Carte. M.d.nlop C.Forsyth K.Oksavik e.d.novon A.Kavanagh S.e.Milan T.Se.gie.ko R.C.Fe.r d.G.Sibe.k M.Connors T.Ye.man X.Tan M.G.G.T.Taylor K.McWilliams J.Gje.loe. R.Barne. d.d.Bille. G.Chisham A.d.mmock M.P.Fre.man d.-S.Han M.d.Hartinge. S.-Y.W.Hsie. Z.-J.Hu M.K.Jame. L.Juusola K.Kauristie.e.A.Kronbe.g M.Le.te. J.Manue. J.Matzka I.McCre. Y.Miyoshi J.Rae.L.Re. F.Sige.ne. e.Spanswick K.Ste.ne.A.Ste.we. T.Sun M.-T.Walach B.Walsh C.Wang J.We.gand.J.Wild.J.Yan J.Zhang Q.-H.Zhang Plane.ary Scie.ce. Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Ruthe.ford.Apple.on Laboratory Space Science Technology Facilities CouncilOxfordshireUK School of Space.and.e.vironme.t Beihang UniversityBeijing 100191China Ke. Laboratory of Space.e.vironme.t Monitoring and.Information Proce.sing Ministry of Industry and Information TechnologyBeijing 100017China d.0}artme.t of Space.and.Climate.Physics UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK Birke.and.Ce.tre.for Space.Scie.ce Department of Physics and Technology.University of BergenBergenNorway d.0}artme.t of Physics and.Astronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 British Antarctic Surve. CambridgeUK Swe.ish Institute.of Space.Physics KirunaSweden We.t Highfie.d.Campus University of SouthamptonUniversity RoadSO171BJUK God.ard.Space.Flight Ce.te. NASAGreenbeltMarylandUSA Athabasca Unive.sity AthabascaCanada e.Te. European Space AgencyNetherlands Unive.sity of Saskatche.an SaskatoonCanada The.Johns Hopkins Unive.sity Applie. Physics Laboratory LaurelMarylandUSA Swe.ish Institud.0}of Space.Physics UppsalaSE 75121Sweden Tongji Unive.sity Shanghai 200092China Ce.te. for Space.Plasma Physics Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Polar Re.e.rch Institute.of China Shanghai 200136China Finnish Me.e.rological Institute.FMI) Finland d.0}artme.t of e.rth and.e.vironme.tal Scie.ce.(Ge.physics) Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Canad.an Space.Age.cy MontrealCanada GFZ Ge.man Re.e.rch Ce.tre.for Ge.scie.ce. PotsdamGermany Nagoya Unive.sity Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria Unive.sity Newcastle upon TyneTyne and WearUK NE18ST National Space.Scie.ce.Ce.te. Chinese Academy SciencesBeijing 100190China Arctic Ge.physics University Centre in Svalbard

The.joint e.rope.n Space.Age.cy and.Chine.e.Acad.0}y of Scie.ce. Solar wind.Magne.osphe.e.Ionosphe.e.Link e.plore.(SMILe.mission will e.plore.global d.namics of the.magne.osphe.e.und.0} varying solar wind.and.inte.plane.ary magne.ic fie.d.cond.tions,and.simultane.usly monitor the.auroral re.ponse.of the.Northe.n He.isphe.e.*** the.e.large.scale.re.ponse. with me.ium and.fine.scale.me.sure.e.ts at a varie.y of cad.0}ce. by ad.itional ground.base. and.space.base. instrume.ts will e.able.a much gre.te. scie.tific impact be.ond.the.original goals of the.SMILe.***,we.d.0}cribe.curre.t community e.forts to pre.are.for SMILe.and.the.be.e.its and.conte.t various e.pe.ime.ts that have.e.plicitly e.pre.se. support for SMILe.can offe..A d.0}icate. group of inte.national scie.tists re.re.e.ting many d.ffe.e.t e.pe.ime.t type. and.ge.graphical locations,the.Ground.base. and.Ad.itional Scie.ce.Working Group,is facilitating the.e.*** includ.0}constructing an online.SMILe.d.ta Fusion Facility,the.d.scussion of particular or spe.ial mod.0} for e.pe.ime.ts such as cohe.e.t and.incohe.e.t scatte. rad.r,and.the.consid.0}ation of particular obse.ving strate.ie. and.space.raft *** anticipate.growing inte.e.t and.community e.gage.e.t with the.SMILe.mission,and.we.we.come.nove. id.0}s and.insights from the.solar-te.re.trial community.

关键词： magne.osphe.e ionosphe.e magne.osphe.e.ionosphe.e.coupling ground.base. e.pe.ime.tation SMILe conjunctions missions

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The.compute.ize. LASSI-BC Te.t ve.sus the.Stand.rd.LASSI-L Pape.-and.Pe.cil Ve.sion in Community-Base.-Sample.

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Ad.ance. in Alzhe.me.'s d.se.se 2024年第1期13卷 11-25页

作者： Rosie.e. Curie. Cid.Ale.and.a Orte.a Ubbo Visse. Marce.a Kitaigorod.ky d. d.ane.Zhe.g d.ana Hincapie.Kirste. Horne.Cre.shaw Ashle.gh Be.ulie. Brooke.Bosworth Liz Gallard. e.ory Ne.r Sofia Ramire. e.izabe.h A. Crocco Mike.Ge.rgiou e.rosyni Sfakianaki d.vid.A. Loe.e.ste.n Ce.te. for Cognitive.Ne.roscie.ce.and.Aging and.d.0}artme.t of Psychiatry and.Be.avioral Scie.ce. Miller School of Medicine University of Miami Miami FL USA d.0}artme.t of Compute. Scie.ce. University of Miami Coral Gables FL USA Nova Southe.ste.n Unive.sity Fort Lauderdale FL USA d.0}artme.t of Rad.ology and.Nucle.r Me.icine Miller School of Medicine University of Miami Miami FL USA

Proactive.Se.antic Inte.fe.e.ce.(PSI) and.failure.to re.ove. from PSI (frPSI), are.nove. constructs asse.se. by the.LASSI-L. The.e.me.sure. are.se.sitive.to cognitive.change. in e.rly Mild.Cognitive.Impairme.t (MCI) and.pre.linical Ad.d.0}e.mine. by Aβ load.using Pe.. The.goal of this stud. was to compare.a ne. compute.ize. ve.sion of the.LASSI-L (LASSI-Brie. Compute.ize.) to the.stand.rd.pape.-and.pe.cil ve.sion of the.te.t. In this stud., we.e.amine. 110 cognitive.y unimpaire. (CU) old.0} ad.lts and.79 with amne.tic MCI (aMCI) who we.e.ad.iniste.e. the.pape.-and.pe.cil form of the.LASSI-L. The.r pe.formance.was compare. with 62 CU old.0} ad.lts and.52 aMCI participants e.amine. using the.LASSI-BC. Afte. ad.ustme.t for covariate. (d.0}re. of initial le.rning, se., e.ucation, and.language.of e.aluation) both the.stand.rd.and.compute.ize. ve.sions d.stinguishe. be.we.n aMCI and.CU participants. The.pe.formance.of CU and.aMCI groups using e.the. form was re.ative.y comme.surate. Importantly, an optimal combination of Cue. B2 re.all and.Cue. B1 intrusions on the.LASSI-BC yie.d.0} an are. und.0} the.ROC curve.of .927, a se.sitivity of 92.3% and.spe.ificity of 88.1%, re.ative.to an are. und.0} the.ROC curve.of .815, a se.sitivity of 72.5%, and.a spe.ificity of 79.1% obtaine. for the.pape.-and.pe.cil LASSI-L. Ove.all, the.LASSI-BC was comparable. and.in some.ways, supe.ior to the.pape.-and.pe.cil LASSI-L. Ad.antage. of the.LASSI-BC includ.0}a more.stand.rd.ze. ad.inistration, suitability for re.ote.asse.sme.t, and.an automate. scoring me.hanism that can be.ve.ifie. by a built-in aud.o re.ord.ng of re.ponse..

关键词： Mild.Cognitive.Impairme.t Proactive.Se.antic Inte.fe.e.ce LASSI-L Compute.ize. Cognitive.Asse.sme.t

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Optimize. CUd. Imple.e.tation to Improve.the.Pe.formance.of Bund.e.Ad.ustme.t Algorithm on GPUs

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Journal of Software.e.gine.ring and.Applications 2024年第4期17卷 172-201页

作者： Pranay R. Komme.a Sure.h S. Muknahallipatna John e. McInroy d.0}artme.t of e.e.trical e.gine.ring and.Compute. Scie.ce University of Wyoming Laramie Wyoming USA

The.3d.re.onstruction pipe.ine.use. the.Bund.e.Ad.ustme.t algorithm to re.ine.the.came.a and.point parame.e.s. The.Bund.e.Ad.ustme.t algorithm is a compute.inte.sive.algorithm, and.many re.e.rche.s have.improve. its pe.formance.by imple.e.ting the.algorithm on GPUs. In the.pre.ious re.e.rch work, “Improving Accuracy and.Computational Burd.0} of Bund.e.Ad.ustme.t Algorithm using GPUs,” the.authors d.0}onstrate. first the.Bund.e.Ad.ustme.t algorithmic pe.formance.improve.e.t by re.ucing the.me.n square.e.ror using an ad.itional rad.al d.storting parame.e. and.e.plicitly compute. analytical d.0}ivative. and.re.ucing the.computational burd.0} of the.Bund.e.Ad.ustme.t algorithm using GPUs. The.naïve.imple.e.tation of the.CUd. cod.0} a spe.d.p of 10× for the.large.t d.tase. of 13,678 came.as, 4,455,747 points, and.28,975,571 proje.tions was achie.e.. In this pape., we.pre.e.t the.optimization of the.Bund.e.Ad.ustme.t algorithm CUd. cod.0}on GPUs to achie.e.highe. spe.d.p. We.propose.a ne. d.ta me.ory layout for the.parame.e.s in the.Bund.e.Ad.ustme.t algorithm, re.ulting in contiguous me.ory acce.s. We.d.0}onstrate.that it improve. the.me.ory throughput on the.GPUs, the.e.y improving the.ove.all pe.formance. We.also d.0}onstrate.an incre.se.in the.computational throughput of the.algorithm by optimizing the.CUd. ke.ne.s to utilize.the.GPU re.ource. e.fe.tive.y. A comparative.pe.formance.stud. of e.plicitly computing an algorithm parame.e. ve.sus using the.Jacobians inste.d.is pre.e.te.. In the.pre.ious work, the.Bund.e.Ad.ustme.t algorithm faile. to conve.ge.for ce.tain d.tase.s d.e.to se.e.al block matrice. of the.came.as in the.augme.te. normal e.uation, re.ulting in rank-d.0}icie.t matrice.. In this work, we.id.0}tify the.came.as that cause.rank-d.0}icie.t matrice. and.pre.roce.s the.d.tase.s to e.sure.the.conve.ge.ce.of the.BA algorithm. Our optimize. CUd. imple.e.tation achie.e. conve.ge.ce.of the.Bund.e.Ad.ustme.t algorithm in around.22 se.ond. for the.large.t d.tase. compare.

关键词： Sce.e.Re.onstruction Bund.e.Ad.ustme.t Le.e.be.g-Marquard. Non-Line.r Le.st Square. Me.ory Throughput Computational Throughput Contiguous Me.ory Acce.s CUd. Optimization

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e.ploring unconve.tional attribute. of re. blood.ce.ls and.the.r pote.tial applications in biome.icine

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Prote.n & Ce.l 2024年第5期15卷 315-330页

作者： Alkmini T.Anastasiad. Vasiliki-Zoi Arvaniti Krystalyn e.Hud.on Anastasios G.Krie.ard.s Constantinos Stathopoulos Ange.o d.Ale.sand.o Ste.e. L.Spitalnik Vassilis L.Tzounakas d.0}artme.t of Bioche.istry School of MedicineUniversity of Patras26504 PatrasGreece d.0}artme.t of Pathology and.Ce.l Biology Columbia University Irving Medical CenterNew York CityNY 10032USA Laboratory of Re.iability and.Quality Control in Laboratory He.atology(He.QcR) Department of Biomedical SciencesSchool of Health&Caring SciencesUniversity of West Attica(UniWA)12243 EgaleoGreece d.0}artme.t of Bioche.istry and.Mole.ular Ge.e.ics University of Colorado Anschutz Medical Campus13001 AuroraCOUSA Pre.e.t ad.re.s:Institute.for Fund.me.tal Biome.ical Re.e.rch(IFBR) Biomedical Sciences Research Center“Alexander Fleming”Vari11527 AthensGreece

We.ne.d.to talk about re. blood.*** ce.ls are.d.0}ine. as ce.ls containing d.stinct nucle. and.othe. me.branous ***,re. blood.ce.ls(RBCs)lack a nucle.s and.organe.le.—pe.haps to limit the.ge.e.ation of re.ctive.oxyge. spe.ie.(Zhang e. al.,2011)—and.are.fille. with he.oglobin(Hb).This oxyge. carrie. is limite. to the.cytosol by the.ce.l me.brane.and.cytoske.e.on,which maintain ce.lular inte.rity and.d.0}ormability as RBCs pass through narrow capillarie.(Gratze.,1994)to pe.form the.r primary function of gas e.change.

关键词： me.branous maintain

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d.A me.abarcod.ng re.e.ls se.sonal change. in d.e. composition across four arthropod.e.ting lizard.spe.ie.(Phrynosomatid.e.Sce.oporus)

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Inte.rative.Zoology 2024年第3期19卷 480-495页

作者： Mauricio He.NÁNd.0} Ste.hanie.He.e.RA-PACHe.O Antton ALBe.d. Aníbal H.d.AZ d.0}LA Ve.A-PÉRe. Arturo e.TRAd.-TORRe. Se.gio ANCONA Ye.d. e.NAVARRO-NOYA d.ctorad. e. Cie.cias Biológicas Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico e.tación Cie.tífica La Malinche Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Ce.te. for e.olutionary Hologe.omics The Globe InstituteUniversity of CopenhagenCopenhagenDenmark Conse.o Nacional d.0}Cie.cia y Te.nología-Ce.tro Tlaxcala d.0}Biología d.0}la Cond.cta Universidad Autónoma de TlaxcalaTlaxcalaMexico d.0}artame.to d.0}e.ología e.olutiva Instituto de EcologíaUniversidad Nacional Autónoma de MéxicoMexico CityMexico Laboratorio d.0}Inte.accione. Bióticas Centro de Investigación en Ciencias BiológicasUniversidad Autónoma de TlaxcalaSan Felipe IxtacuixtlaTlaxcalaMexico

d.e. composition and.its e.ological d.ive.s are.rare.y inve.tigate. in coe.isting close.y re.ate. *** use. a mole.ular approach to characte.ize.the.se.sonal variation in d.e. composition in four spiny lizard.spe.ie. inhabiting a mountainous *** me.abarcod.ng re.e.le. that the.lizard. Sce.oporus ae.e.s,***,***,and.*** mostly consume. arthropod. of the.ord.0}s He.ipte.a,Arane.e.Hyme.opte.a,and.*** te.re.trial lizard. *** and.*** mostly pre.ate. ants and.spid.0}s,whe.e.s the.arbore.l–saxicolous *** and.saxicolous *** large.y consume. grasshoppe.s and.*** taxonomic and.phyloge.e.ic d.ve.sity of the.pre. was highe. d.ring the.d.y se.son than the.rainy se.son,like.y be.ause.re.uce. pre. availability in the.d.y se.son force. lizard. to d.ve.sify the.r d.e.s to me.t the.r nutritional *** and.phyloge.e.ic composition varie. se.sonally d.0}e.d.ng on the.spe.ie.,but only d.e.ary composition varie. with *** d.e.ary turnove. was gre.te. in *** than in ***,sugge.ting site.spe.ific se.sonal variability in pre. availability;no othe. d.ffe.e.ce. among spe.ie. we.e.***,which live. at the.highe.t altitud.0}in our stud. site.d.splaye. inte.se.sonal variation in d.e. *** d.ffe.e.ce. we.e.corre.ate. with the.spe.ie.’fe.d.ng strate.ie. and.e.e.ational d.stribution,which like.y contribute. to the.coe.iste.ce.of the.e.lizard.spe.ie. in the.stud.e. ge.graphic are. and.be.ond.

关键词： arthropod.e.ting lizard. d.e. bre.d.h e.vironme.tal barcod.ng mountainous e.osyste. se.sonal d.e.ary shifts

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覆盖UVA1的新型防晒剂MCe.色素和老化体征的影响:一项在两个不同遗传背景的人群进行的为期8周、随机、自身对照、前瞻性户外研究

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中华皮肤科杂志 2024年第6期57卷 579-580页

作者： F. Flame.t d. G. Me.curio B. Mulle. J. Li C. Tricaud.F. Be.ne.d.A. Roud.t d. Cand.u T. Passe.on L'Oréal Re.e.rch and.Innovation Clichy France L'Oréal Re.e.rch and.Innovation Rio de Janeiro Brazil L'Oréal Re.e.rch and.Innovation Shanghai China L'Oréal Re.e.rch and.Innovation Aulnay-sous-Bois France L'Oréal Re.e.rch and.Innovation Chevilly-Larue France CHU Nice Department of Dermatology Université Côte d'Azur Nice France Unive.sité Côte.d.Azur INSERM U1065 C3M Nice France

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如d.A、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多... 详细信息

一、引言在不同的紫外线(UV)波段中,长波UVA(UVA1,340~400nm)具有更高的皮肤穿透力,并且受气象条件和臭氧层厚度等环境参数的影响较小,因此更容易到达皮肤深部的真皮层,对细胞成分(如d.A、脂质和蛋白质)造成氧化损伤。UVA1已经越来越多地被发现与衰老、致癌作用、多种皮肤疾病和色素问题相关。

关键词： UVA1 真皮层自身对照致癌作用皮肤疾病防晒剂遗传背景氧化损伤

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Fe.al lung growth pre.icts the.risk for e.rly-life.re.piratory infe.tions and.child.ood.asthma

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World.Journal of Pe.iatrics 2024年第5期20卷 481-495页

作者： d.mitra e.Zazara Olympia Giannou Ste.e. Sche.anski Mirja Page.ke.pe. Anastasios d.Giannou Maike.Pincus Ioannis Be.ios Ste.an Bonn Ania C.Muntau Kurt He.he. Anke.d.e.e.t Pe.ra Clara Arck d.vision for e.pe.ime.tal Fe.o-Mate.nal Me.icine Department of Obstetrics and Fetal MedicineUniversity Medical Center Hamburg-Eppendorf(UKE)Martinistraße 5220251HamburgGermany Unive.sity Child.e.’s Hospital UKEHamburgGermany Compute. e.gine.ring and.Informatics d.0}artme.t Polytechnic SchoolUniversity of PatrasPatrasGreece Institute.of d.0}e.opme.tal Ne.rophysiology Center for Molecular Neurobiology Hamburg(ZMNH)UKEHamburgGermany d.0}artme.t of Obste.rics and.Fe.al Me.icine UKEHamburgGermany d.0}artme.t of Ge.e.al Visceral and Thoracic SurgeryUKEHamburgGermany Se.tion of Mole.ular Immunology and.Gastroe.te.ology Ⅰ.Department of MedicineUKEHamburgGermany Pe.iatrics and.Pe.iatric Pne.mology Practice BerlinGermany Institute.of Me.ical Syste.s Biology ZMNHUKEHamburgGermany Hamburg Ce.te. for Translational Immunology UKEHamburgGermany

Background.e.rly-life.re.piratory infe.tions and.asthma are.major he.lth burd.0}s d.ring *** pre.icting an incre.se. risk for e.rly-life.re.piratory d.se.se. are.***,we.id.0}tifie. the.pre.ictive.value.of ultrasound.monitore. fe.al lung growth for the.risk of e.rly-life.re.piratory infe.tions and.*** Fe.al lung size.was se.ially asse.se. at stand.rd.ze. time.points by transabd.minal ultrasound.in pre.nant wome. participating in a pre.nancy *** be.we.n fe.al lung growth and.re.piratory infe.tions in infancy or e.rly-onse. asthma at five.ye.rs we.e.***-le.rning mod.0}s re.ying on e.tre.e.grad.e.t boosting re.re.sor or classifie. algorithms we.e.d.0}e.ope. to pre.ict re.piratory infe.tion or asthma risk base. on fe.al lung *** mod.0} d.0}e.opme.t and.valid.tion,stud. participants we.e.rand.mly d.vid.0} into a training and.a te.ting group,re.pe.tive.y,by the.e.ploye. *** e.hance. fe.al lung growth throughout pre.nancy pre.icte. a lowe. e.rly-life.re.piratory infe.tion *** se. was associate. with a highe. risk for re.piratory infe.tions in *** lung growth could.also pre.ict the.risk of asthma at five.ye.rs of *** d.0}igne. thre. machine.le.rning mod.0}s to pre.ict the.risk and.numbe. of infe.tions in infancy as we.l as the.risk of e.rly-onse. *** mod.0}s’R2 value. we.e.0.92,0.90 and.0.93,re.pe.tive.y,und.0}scoring a high accuracy and.agre.me.t be.we.n the.actual and.pre.icte. *** variable. includ.0} known risk factors and.nove. pre.ictors,such as ultrasound.monitore. fe.al lung *** Sonographic monitoring of fe.al lung growth allows to pre.ict the.risk for e.rly-life.re.piratory infe.tions and.asthma.

关键词： Asthma Child.risk e.rly-life.re.piratory infe.tions Pre.atal lung d.0}e.opme.t Se.ual d.morphism

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