Me.e.chymal ste. ce.ls(MSCs)and the.r byproducts have.be.n wide.y validate. as pote.tial the.ape.tic products for re.e.e.ative.*** the.ape.tic e.fe.ts re.ult mainly from the.paracrine.activity of MSCs,which consists o...
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Me.e.chymal ste. ce.ls(MSCs)and the.r byproducts have.be.n wide.y validate. as pote.tial the.ape.tic products for re.e.e.ative.*** the.ape.tic e.fe.ts re.ult mainly from the.paracrine.activity of MSCs,which consists of the.se.re.ion of bioactive.mole.ule.,whe.he. dispe.se. in me.ium conditione. by ce.l culture.or e.capsulate. in e.trace.lular *** composition of the.MSC se.re.ome.which re.re.e.ts the.se. of the.e.se.re.e. ce.lular products,is crucial for the.pe.formance.of the.de.ire. the.ape.tic *** ce.l culture.strate.ie. have.be.n e.ploye. to adjust the.se.re.ome.composition of MSCs to obtain the.be.t the.ape.tic re.ponse. for diffe.e.t clinical ***,the.manipulation of culture.conditions has focuse. mainly on the.use.of diffe.e.t bioche.ical e.e.e.ts for the.pre.onditioning of MSCs and le.s on the.physical conditions of the.ce.l culture.***,we.offe. our point of vie. re.arding the.importance.of the.physical prope.tie. of ce.l culture.substrate. and the.r me.hanotransduction re.ponse. in pre.onditioning the.MSCs *** highlight the.re.e.ance.of studying me.hanotransduction e.e.ts associating ce.l morphology and the.modulation of ge.e.e.pre.sion to customize.and e.pand the.use.of MSCs se.re.ome..
Purpose.of the.work was to quantify the.workloads and the.ne.rologist’s commitme.t in e., to ve.ify the.manage.e.t of urge.cie. and appropriate.e.s of ne.rological counse.ing re.ue.ts. Ne.rologic e.e.ge.cie. are.fre....
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Purpose.of the.work was to quantify the.workloads and the.ne.rologist’s commitme.t in e., to ve.ify the.manage.e.t of urge.cie. and appropriate.e.s of ne.rological counse.ing re.ue.ts. Ne.rologic e.e.ge.cie. are.fre.ue.t in e.de.ly patie.ts and are.associate. with high morbidity and mortality. Due.to the.aging population, ne.rologic pathologie. in e.e.ge.cy room (e.) are.wide.y e.pe.te. to incre.se. The.role.of the.ne.rologist in this conte.t is controve.sial. Me.hods: in 14 ope.ative.units of ne.rology a prospe.tive.colle.tion of ne.rological e.aluations in e. was carrie. out using boards of de.e.tion of the.most fre.ue.t ne.rological clinical picture. se.n in the.course.of a we.k. Data we.e.colle.te. from 738 case.. Atte.tion was focuse. on ce.e.rovascular dise.se. (CVD), impairme.t of consciousne.s, e.ile.sy, he.dache. dizzine.s, he.d trauma and disorde.s of the.pe.iphe.al ne.vous syste. (PNS). Achie.e.e.ts: ne.rological consultations we.e.on ave.age.5% of total acce.se. to e.. The.most common pathology se.n was ische.ic stroke. Afte. counse.ing most patie.ts we.e.discharge. home. The.CVD re.uire. the.gre.te.t commitme.t to the.spe.ialist. The.use.ulne.s of the.spe.ialize. ne.rological “filte.” has be.n confirme. in a non-simple.ope.ative.conte.t, aime. at optimizing the.appropriate.e.s of the.hospitalization and the.e.onomy of the.diagnostic path.
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