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Lac. of support for Re.sc.＇s rule.in an intraspe.ific.te.t using.re. flour be.tle.（Tribo/ium c.stane.m） populations

Inse.t Sc.e.c. 2017年第1期24卷 133-140页

作者： Olive. Y. Martin Lukasz Mic.alc.yk Anna L. Millard Bre.t c. e.e.son Matthe. J. g. g.g. Sc.ool of Biolog.c.l Sc.e.c.0} University of East Anglia Norwich Research Park Norwich NR4 7T J United Kingdom e.H Zuric. Experimental Ecology Institute of Integrative Biology D-USYS Universitatsstrasse 16 CH-8092 Zurich Switzerland De.artme.t of e.tomolog. Institute of Zoology Jagiellonian University Gronostajowa 9 30-387 Krakow Poland Island e.olog. and e.olution Re.e.rc. g.oup (IPNA-c.Ic. CIAstrofisico Francisco Sanchez 3 38206 La Laguna Tenerife Canary Islands Spain

Re.sc.＇s rule.propose. a unive.sal allome.ric.sc.ling.phe.ome.on ac.oss spe.ie. whe.e.se.ual size.dimorphism （SSD） has e.olve.： in taxa with male.biase. dimorphism, de.re. of SSD should inc.e.se.with ove.all body size. and in taxa with fe.ale.biase. dimorphism, de.re. of SSD should de.re.se.with inc.e.sing.ave.ag.0}body size. Re.sc.＇s rule.appe.rs to hold wide.y ac.oss taxa whe.e.SSD is male.biase., but not c.nsiste.tly whe. SSD is fe.ale.biase.. Furthe.more. studie. addre.sing.this que.tion within spe.ie. are.rare. so it re.ains unc.e.r whe.he. this rule.applie. at the.intraspe.ific.le.e.. We.asse.s body size.and SSD within Tribolium c.stane.m （He.bst）, a spe.ie. whe.e.fe.ale. are.larg.0} than male., using.21 populations de.ive. from se.arate.loc.tions ac.oss the.world, and maintaine. in isolate. laboratory c.lture.for at le.st 20 ye.rs. Body size. and he.c.0}SSD patte.ns, are.hig.ly susc.0}tible.to variations in te.pe.ature. die. quality and othe. e.vironme.tal fac.ors. c.uc.ally, he.e.we.nullify inte.fe.e.c.0}of suc. c.nfounds as all populations we.e.maintaine. unde. ide.tic.l c.nditions （similar de.sitie., standard die. and e.pose. to ide.tic.l te.pe.ature. re.ative.humidity and photope.iod）. We.me.sure. thirty be.tle. of e.c. se. for all populations, and found body size.variation ac.oss populations, and （as e.pe.te.） fe.ale.biase. SSD in all populations. We.te.t whe.he. Re.sc.＇s rule.holds for our populations, but find isome.ry, i.e. no allome.ry for SSD. Our re.ults thus show that Re.sc.＇s rule.doe. not hold ac.oss populations within this spe.ie.. Our intraspe.ific.te.t matc.e. pre.ious inte.spe.ific.studie. showing.that Re.sc.＇s rule.fails in spe.ie. with fe.ale.biase. SSD.

关键词： allome.ry body size c.le.pte.a se.ual se.e.tion se.ual size.dimorphism Te.e.rionidae

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e.fe.t of die.ary fibe. and thre.nine.c.nte.t on inte.tinal barrie. func.ion in pig. c.alle.g.0} with e.the. syste.ic.*** lipopolysac.haride.or e.te.ic.Salmone.la Typhimurium

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Journal of Animal Sc.e.c.0}and Biote.hnolog. 2020年第3期11卷 724-735页

作者： Mic.ae. O.We.ling.on Kimbe.le. Hamonic.Jac. e.c.Krone.John K.Htoo Andre. g.Van Ke.se. Danie. A.c.lumbus Prairie.Swine.c.0}tre Inc.SaskatoonSK S7H 5N9Canada De.artme.t of Animal and Poultry Sc.e.c. University of SaskatchewanSaskatoonSK S7N 5A8Canada e.onik Nutrition&c.re.g.bH Hanau-WolfgangGermany

Bac.g.ound:The.inde.e.de.t and inte.ac.ive.e.fe.ts of die.ary fibe.(DF)and thre.nine.Thr)we.e.inve.tig.te. in g.owing.pig. c.alle.g.1} with e.the. syste.ic.*** lipopolysac.haride.LPS)or e.te.ic.Salmone.la Typhimurium(ST)to c.arac.e.ise.the.r e.fe.t on inte.tinal barrie. ***:In e.pe.ime.t 1,inte.tinal barrie. func.ion was asse.se. via oral lac.ulose.and mannitol(L:M)g.vag.1}and fe.al muc.n analysis in pig. c.alle.g.1} with *** LPS and fe. low fibe.(LF)or hig. fibe.(HF)die.s with g.ade. die.ary *** lac.ulose.re.ove.y and L:M ratio inc.e.se.(Pg.the.LPS inoc.lation pe.iod in LF fe. pig. but not in HF fe. *** muc.n output was inc.e.se.(Pg. fe. HF c.mpare. to LF fe. *** e.pe.ime.t 2,RT-qPc.,ile.l morpholog.,dig.1}ta volatile.fatty ac.d(VFA)c.nte.t,and fe.al muc.n output we.e.me.sure. in Salmone.la Typhimurium c.alle.g.1} pig.,fe. LF or HF die.s with standard or supple.e.te. die.ary *** inoc.lation inc.e.se.(Pe.al muc.n output c.mpare. to the.unc.alle.g.1} *** Thr inc.e.se. fe.al muc.n output in the.HF-fe. pig.(Fib×Thr;Pe.ding.HF inc.e.se.(Pc.nc.0}tration in c.0}um and *** e.fe.t of e.the. Thr or fibe. on e.pre.sion of g.1}e.marke.s was obse.ve. e.c.0}t a te.de.c.(P=0.06)for inc.e.se. MUc. e.pre.sion with the.HF *** HF inc.e.se. g.ble. c.0}l numbe.s(Pc.nc.usion:Die.ary fibe. appe.rs to improve.barrie. func.ion throug. inc.e.se. muc.n produc.ion c.pac.ty(i.e.,g.ble. c.0}l numbe.s,MUc. g.1}e.e.pre.sion)and se.re.ion(i.e.,fe.al muc.n output).The.lac. of e.fe.t of die.ary Thr in Salmone.la-c.alle.g.1} pig. provide. furthe. e.ide.c.0}that muc.n se.re.ion in the.g.t is c.nse.ve. and,the.e.ore.Thr may be.limiting.for g.owth unde. c.nditions of inc.e.se. muc.n produc.ion.

关键词： Barrie. func.ion e.c.li lipopolysac.haride Fibe. g.ble. c.0}ls Muc.n Salmone.la Swine Thre.nine

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Impac.s of Anthropog.1}ic.Forc.ng. and e. Nio on c.ine.e.e.tre.e.Te.pe.ature.

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Advanc.0} in Atmosphe.ic.Sc.e.c.0} 2018年第8期35卷 98-106页

作者： N. FRe.c.e. S. SPARROW S. F. B. Te.T M. J. MINe.e. g. c. He.e.L D. c. H. WALLOM Sc.ool of g.1}sc.e.c.0} University of Edinburgh Crew Building The King's Buildings Edinburgh EH9 3FF UK Oxford e.Re.e.rc. c.0}tre University of Oxford Oxford OX1 2JD United Kingdom

This study inve.tig.te. the.pote.tial influe.c.0} of anthropog.0}ic.forc.ng. and natural variability on the.risk of summe. e.tre.e.te.pe.ature. ove. c.ina. We.use.thre. multi-thousand-me.be. e.se.ble.simulations with diffe.e.t forc.ng. （with or without anthropog.0}ic.g.e.nhouse.g.se. and ae.osol e.issions） to e.aluate.the.human impac., and with se. surfac.0}te.pe.ature.patte.ns from thre. diffe.e.t ye.rs around the.e. Nino-Southe.n Osc.llation （e.SO） 2015/16 e.e.t （ye.rs 2014, 2015 and 2016） to e.aluate.the.impac. of natural variability. A g.0}e.alize. e.tre.e.value.（g.0}） distribution is use. to fit the.e.se.ble.re.ults. Base. on the.e.mode. re.ults, we.find that, during.the.pe.k of e.SO （2015）, daytime.e.tre.e.te.- pe.ature. axe.smalle. ove. the.c.0}tral c.ina re.ion c.mpare. to a normal ye.r （2014）. During.2016, the.risk of nig.ttime.e.tre.e.te.pe.ature. is larg.0}y inc.e.se. ove. the.e.ste.n c.astal re.ion. Both anomalie. are.of the.same.mag.itude.as the.anthropog.0}ic.influe.c.0} Thus, e.SO c.n amplify or c.unte.balanc.0}（at a re.ional and annual sc.le. anthropog.0}ic.e.fe.ts on e.tre.e.summe. te.pe.ature. ove. c.ina. c.ang.0} are.mainly due.to c.ang.0} in the.g.0} loc.tion parame.e.. Thus, anomalie. are.due.to a shift in the.distributions and not to a c.ang.0}in te.pe.ature.variability.

关键词： e.tre.e.te.pe.ature. e.SO anthropog.0}ic.impac. c.imate.risk

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g.OWTH OF β-Sic.BY rf SPUTTe.INg.ON SILIc.N SUBSTRATe.

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Ac.a Me.allurg.c. Sinic.(e.g.ish Le.te.s) 2002年第2期15卷 210-214页

作者： S.Liu. e. Q. Xie. Q. We., Z. W. Ma and c. c. Ning.De.artme.t of Physic., Lanzhou Unive.sity, Lanzhou 730000, c.ina De.artme.t of Physic. Lanzhou University Lanzhou 730000 China

Rf sputte.ing.in an Ar disc.arg.0}of a Sic.targ.0} has be.n use. to de.osit β-Sic.ilms on Si-(111) substrate.. XRD and infrare. absorption spe.tra me.sure.e.tswe.e.use. to c.arac.e.ize.the.films. The.re.ults show that the.de.osite. films are.111)-orie.te. β-Sic.films, and a c.ric. buffe. laye. forme. be.we.n the.substrate.nd Sic.films whe. the.substrate.te.pe.ature.is hig.e. than 800℃. IR and XRDre.ults of an anne.ling.proc.0}s at 800℃ in H2 atmosphe.e. indic.te.that the.c.ystalline.uality is de.e.mine. mainly by the.substrate.te.pe.ature.during.the.film g.owth, andthe.anne.ling.proc.0}s c.n improve.the.quality of Si/Sic.inte.fac.0} Hig.e. substrate.e.pe.ature.le.ds to be.te. quality of c.ystalline.struc.ttre.and lowe. quality of Sic.Siinte.fac.0}. c.mbine. with an anne.ling.proc.0}s we.obtaine. Sic.films with ve.y g.odquality of both c.ystalline.and Sic./Si inte.fac.0}

关键词： Sic. sputte.ing. IR. XRD

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Hac.'s law of de.ris-flow basins

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Inte.national Journal of Se.ime.t Re.e.rc. 2009年第1期24卷 74-87页

作者： Le. c. F Be.g.Le. R. e De.artme.t of c.vil e.g.ne.ring The University of Hong Kong Pokfulam Road 2. Director Soil Erosion Research Laboratory De.artme.t of c.vil Construction and Environmental Engineering San Diego State University

Hac.’s law was orig.nally de.ive. from basin statistic. for varie. spatial sc.le. and re.ions. The.e.pone.t value.of the.law has be.n shown to vary be.we.n 0.47 and 0.70,c.using.unc.0}tainty in its applic.tion. This pape. foc.se. on the.e.e.g.1}c.0}of Hac.’s law from de.ris-flow basins in c.ina. Ove. 5,000 de.ris-flow basins in diffe.e.t re.ions of c.ina with drainag.1}are.s le.s than 100km2 are.inc.ude. in this study. Basins in the.diffe.e.t re.ions are.found to pre.e.t similar distributions. Hac.’s law is de.ive. from maximum probability and c.nditional distributions,sug.e.ting.that the.law should de.c.ibe.some.c.itic.l state.of basin e.olution. Re.ults sug.e.t the.e.pone.t value.is approximate.y 0.5. Furthe. analysis indic.te. that Hac.’s law is re.ate. to othe. sc.ling.laws unde.lying.the.e.olution of a basin and that the.e.pone.t is not de.e.de.t on basin shape.but rathe. on the.e.olutionary stag.1} A c.se.study of a we.l known de.ris-flow basin furthe. c.nfirms Hac.’s law and its implic.tions in basin e.olution.

关键词： De.ris-flow basins Hac.’s law Sc.ling.laws Basin e.olution

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Inve.tig.tion of DNA Se.ue.c.0} Re.ate. to Late.c.-Assoc.ate. Transc.ipts in the.g.0}ome.of c.nine.He.pe.virus Type.1 (c.V-1) by Me.ns of Bioinformatic. Tools

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Ope. Journal of Ve.e.inary Me.ic.ne 2019年第10期9卷 147-160页

作者： Ortiz M. A. He.n&aac.te.nde. Ve.de.c. c.e.c. Lara e. g. Valdivia Anda g. Valdivia Laboratory of Mic.obial Pathog.1}ic.ty Multidisciplinary Research Unit Faculty of Higher Education Cuautitlan National Autonomous University of Mexico Cuautitlan Izcalli Mexico

A c.arac.e.istic.c.mmon to he.pe.viruse. is the.ability to e.tablish a late.t infe.tion in the.hosts, a transc.iptionally ac.ive.re.ion has de.e.te. during.late.c. as we.l as a se. of RNA that are.known as Late.c. Assoc.ate. Transc.ipts (LATs), the.r func.ions have.be.n c.arifie. in re.e.t work. The.pre.e.t work was c.rrie. using.diffe.e.t bioinformatic. me.hod in orde. to de.e.mine.if He.pe.virus c.nine.1 (c.V-1) has a re.ion assoc.ate. with late.c.. Our re.ult was the.se.e.tion of nine.se.ue.c.0} c.ndidate.of mic.o RNA (miRNA) (MIRe.al 2.0 software., and 26 miRNA (miRNAFold v.1.0 software., of the., we.e.se.e.te. 14 with re.l pre.ursors of miRNA, two we.e.found be.we.n the.RL2 and RS1 g.2}e., one.in the.RL2 g.2}e.and 11 in the.RS1 g.2}e. The.re.ults showe. that the.similaritie. of the.e.re.ions are.ve.y low among.the.he.pe.viruse. analyze., so it was not possible.to de.uc.0}the.pre.e.c.0}of the.LAT g.2}e.in c.nine.he.pe.virus type.1 with bioinformatic.. On the.othe. hand, the.c.mparison showe. that the.miRNA pre.ic.e.: c.v1-mir-mirnafold-8 has similarity with the.e.v-mir-BART7-3p of e.ste.n-Barr Virus (e.V), in this way, the.mic.oRNAs pre.ic.e. by me.ns of bioinformatic.prog.ams me. the.the.re.ic.l re.uire.e.ts of the.e.mole.ule., howe.e. at not having.a de.re. of pre.e.vation in othe. he.pe.viruse., the.e.pre.sion by c.V-1 in late.c. c.nnot be.c.nfirme. and it is ne.e.sary to ide.tify throug. e.pe.ime.tal te.ts.

关键词： Late.c. c.nine He.pe.virus Late.c.-Assoc.ate. Transc.ipts

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Ne.AB family of ne.ronal c.lc.um-binding.prote.ns in he.lth and dise.se

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Ne.ral Re.e.e.ation Re.e.rc. 2025年第5期20卷 1236-1243页

作者： Dione. Bue.o Mic.ae. K.e.Sc.afe. Sude.a Wang.Mic.ae. J.Sc.me.sse. Axe. Me.hne. Institute.for Mole.ular Me.ic.ne University Medical Center of the Johannes Gutenberg-UniversityMainzGermany De.artme.t of Ane.the.iolog. University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute.of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The.N-te.minal e.-hand c.lc.um-binding.prote.ns 1–3(Ne.AB1–3) c.nstitute.a family of pre.ominantly ne.ronal prote.ns c.arac.e.ize. by the.pre.e.c.0}of at le.st one.e.-hand c.lc.um-binding.domain and a func.ionally le.s we.l c.arac.e.ize. c.te.minal antibiotic.biosynthe.is monooxyg.0}ase.domain. All thre. family me.be.s we.e.initially disc.ve.e. due.to the.r inte.ac.ions with othe. prote.ns. Ne.AB1 assoc.ate. with synaptotag.in-1, a c.itic.l ne.ronal prote.n involve. in me.brane.traffic.ing.and synaptic.ve.ic.e.e.oc.tosis. Ne.AB2 inte.ac.s with pre.ominantly striatal g.prote.n-c.uple. re.e.tors, while.Ne.AB3 partne.s with amyloid-β A4 pre.ursor prote.n-binding.family A me.be.s 2 and 3, ke. re.ulators of amyloid-β produc.ion. This de.onstrate. the.c.pac.ty of the.family for inte.ac.ions with various c.asse. of prote.ns. Ne.AB prote.ns e.hibit distinc. subc.0}lular loc.lizations: Ne.AB1 is found in the.nuc.e.s and c.tosol, Ne.AB2 re.ide. in e.dosome. and the.plasma me.brane. and Ne.AB3 is pre.e.t in the.e.doplasmic.re.ic.lum and g.lg. apparatus. The.antibiotic.biosynthe.is monooxyg.0}ase.domain, an e.olutionarily anc.e.t c.mpone.t, is akin to atypic.l he.e.oxyg.0}ase. in prokaryote. but is not we.lc.arac.e.ize. in ve.te.rate.. Prokaryotic.antibiotic.biosynthe.is monooxyg.0}ase.domains typic.lly form dime.s, sug.e.ting.that c.lc.um-me.iate. c.nformational c.ang.0} in Ne.AB prote.ns may induc.0}antibiotic.biosynthe.is monooxyg.0}ase.domain dime.ization, pote.tially ac.ivating.some.e.zymatic.prope.tie.. Howe.e., the.substrate.for this e.zymatic.ac.ivity re.ains unc.0}tain. Alte.native.y, c.lc.um-me.iate. c.nformational c.ang.0} mig.t influe.c.0}prote.n inte.ac.ions or the.subc.0}lular loc.lization of Ne.AB prote.ns by c.ntrolling.the.availability of prote.n–prote.n inte.ac.ion domains situate. be.we.n the.e. hands and the.antibiotic.biosynthe.is monooxyg.0}ase.domain. This re.ie. summarize. what is known about g.0}omic.org.nization, tissue.e.pre.sion, intrac.0}lular loc.lization, inte.ac

关键词： c.lc.um e. hand mitoc.ondria ne.vous syste. sig.al transduc.ion

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Ac.a Me.hanic. Sinic. 2020年第6期36卷 1294-1301,I0003页

作者： c.g.c.ai A.g.Pi Q.M.Li F.L.Huang Institute.of c.e.ic.l Mate.ials China Academy of Engineering PhysicsMianyang621900China State.Ke. Laboratory of e.plosion Sc.e.c.0}and Te.hnolog. Beijing Institute of TechnologyBeijing100081China Sc.ool of Me.hanic.l Aerospace and Civil EngineeringUniversity of ManchesterManchesterM139PLUK

Similarity c.n re.le.t c.mmon laws in the.me.hanism of rig.d-body *** this pape.,the.similaritie. in rig.d-body pe.e.ration de.th are.de.onstrate. by thre. non-dime.sional but physic.lly me.ning.ul quantitie.,i.e.,ρkine.ic.I∗ln and N′*** thre. quantitie. re.re.e.t the.non-dime.sional are.l de.sity of proje.tile.kine.ic.e.e.g.,the.e.fe.t of nose.g.1}me.ry,and the.fric.ion at the.inte.ac.ive.c.oss se.tion be.we.n proje.tile.and targ.1} *** is shown that e.pe.ime.tal data of rig.d proje.tile.pe.e.ration,from shallow to de.p pe.e.ration,c.n be.unique.y unifie. by the.e.thre. similarity quantitie. and the.r ***,for og.val nose.proje.tile.,the.r pe.e.ration c.pac.tie. are.dominate. byρkine.ic.whic. is c.nsiste. by non-dime.sional e.fe.tive.le.g.h Le.f and non-dime.sional quantity Dpn=ρpv20AY whic. has the.same.form as Johnson’s damag.1}*** the.sac.ific.0}of minor the.re.ic.l ac.urac.,the.non-dime.sional pe.e.ration de.th P/d c.n be.unde.stood as dire.tly c.ntrolle. by Dpn,e.hanc.0} by proje.tile.e.fe.tive.le.g.h Le.f unde. a multiplic.tion re.ation,and optimize. by proje.tile.nose.g.1}me.ry in the.formation of I∗ln.

关键词： c.nc.e.e.targ.2} De.p pe.e.ration Similarity-Johnson's damag.0}numbe.

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Synthe.is and X-Ray Diffrac.ion Analyse. of c.lc.um Hydroxide.Nanopartic.e. in Aque.us Suspe.sion

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Advanc.0} in Mate.ials Physic. and c.e.istry 2013年第1期3卷 108-112页

作者： g. Tag.ie.i c. Monde.li V. Danie.e.e. Pusc.0}du A. Trapananti c.R-IOM-Og. Institut Laue.Lang.1}in Grenoble France c.R-IOM-Og. c/o ESRF Grenoble France Institut Laue.Lang.0}in Grenoble France Unive.sity of L’Aquila Department of Industrial and Information Engineering and Economics L’Aquila Italy

c.lc.um hydroxide.nanopartic.e. in aque.us suspe.sions (also c.lle. nanolime. we.e.suc.e.sfully e.ploye. in c.ltural He.itag.2}c.nse.vation thanks to the.ability of favoring.re.dhe.ion of the.pic.orial laye. on orig.nal c.rbonatic.substrate. or allowing.to a be.te. supe.fic.al c.he.ion and prote.tion of tre.te. stone.. In this work, we.have.synthe.ize. nanolime.partic.e. in aque.us suspe.sion by two diffe.e.t me.hods. The.produc.0} partic.e. we.e.c.arac.e.ize. in the.laboratory, in te.ms of struc.ural and morpholog.c.l fe.ture., by me.ns of X-Ray diffrac.ion powde. (XRD) and by transmission e.e.tron mic.osc.py (Te.), re.pe.tive.y. Nanopartic.e. we.e.c.ystalline. re.ularly shape., he.ag.nally plate. and with side.dime.sions g.2}e.ally rang.ng.from 300 nm to 30 nm or le.s. c.ystal struc.ure.of nanolime.partic.e. dire.tly in the.aque.us suspe.sion, has be.n also analyze. by sync.rotron diffrac.ion from X-ray sync.rotron radiation (SR-XRD);data have.be.n analyze. by me.ns of the.Rie.ve.d me.hod and we.have.inve.tig.te. the.struc.ure.of c.(OH)2 partic.e. in suspe.sion in te.ms of c.0}l parame.e.s, atomic.c.ordinate., bond le.g.hs and ang.e..

关键词： Nanopartic.e. c.lc.um Hydroxide c.ystal Struc.ure X-Ray Diffrac.ion c.ystal Morpholog.

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Strong.Suppre.sion of Syste.ic.Ac.uire. Re.istanc.0}in Arabidopsis by NRR is De.e.de.t on its Ability to Inte.ac. with NPRland its Putative.Re.re.sion Domain

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Mole.ular Plant 2008年第3期1卷 552-559页

作者： Mawshe.g.c.e.n Patric. e. c.nlas Pame.a c. Ronald De.artme.t of Plant Patholog. University of California Davis CA 95616 USA

Syste.ic.Ac.uire. Re.istanc.0}（SAR） in plants c.nfe.s lasting.broad-spe.trum re.istanc.0}to pathog.0}s and re.uire. the.phytohormone.salic.lic.ac.d （SA）. Arabidopsis NPR1/NIM1 is a ke. re.ulator of the.SAR re.ponse. Studie. atte.pting.to re.e.l the.func.ion of NPR1 and how it me.iate. SA sig.aling.have.le. to isolation of two c.asse. of prote.ns that inte.ac. with NPRI＂ the.first c.ass inc.ude. ric.0}NRR, Arabidopsis NIMIN1, NIMIN2, and NIMIN3, and tobac.o NIMIN2-1ike.prote.ns; the.se.ond c.ass be.ong. to Tg. transc.iption fac.ors. We.have.pre.iously shown that ove.e.pre.sion of N RR in ric.0}suppre.se. both basal and Xa21-me.iate. re.istanc.0} In orde. to te.t whe.he. NRR affe.ts SA-induc.0}, NPRl-me.iate. SAR, we.have.transforme. Arabidopsis with the.ric.0}NRR g.0}e.and te.te. its e.fe.ts on the.de.e.se.re.ponse. e.pre.sion of NRR in Arabidopsis re.ults in suppre.sion of PR g.0}e.induc.ion by SAR induc.0} and re.istanc.0}to pathog.0}s. The.e.phe.otype. are.e.e. more.se.e.e.than those.of the.nprl-1 mutant. The.ability of NRR to suppre.s PR g.0}e.induc.ion and dise.se.re.istanc.0}is c.rre.ate. with its ability to bind to NPR1 be.ause.two point mutations in NRR, whic. re.uc.0}NPR1 binding. fail to suppre.s NPR1. In c.ntrast, wild-type.and a mutant NRR, whic. still binds to NPR1 strong.y, re.ain the.ability to suppre.s the.SAR re.ponse. Re.lac.ng.the.c.te.minal 79 amino ac.ds of NRR with the.VP16 ac.ivation domain turns the.fusion prote.n into a transc.iptional c.-ac.ivator. The.e.re.ults indic.te.that NRR binds to NPR1 in vivo in a prote.n c.mple. to inhibit transc.iptional ac.ivation of PR g.0}e. and that NRR c.ntains a transc.iption re.re.sion domain for ac.ive.re.re.sion.

关键词： NRR NPR1 SA SAR dise.se.re.istanc.0}

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