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Multi-Ste. Cluste.ing of Smart Me.e.s Time.Se.ie.:Application to De.and Fle.ibility Characte.ization of SMe.Custome.s

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Compute. Mode.ing in e.gine.ring & Scie.ce. 2025年第1期142卷 869-907页

作者： Santiago ba.a.e. Raque. Dormido Natividad Duro De.artme.t of Compute. Scie.ce. and Automatic Control Universidad Nacional de Educación a Distancia(UNED)Madrid28040Spain Ibe.drola Innovation Middle.e.st Doha210177Qatar

Custome. se.me.tation according to load-shape.profile. using smart me.e. data is an incre.singly important application to vital the.planning and ope.ation of e.e.gy syste.s and to e.able.citize.s’participation in the.e.e.gy *** study propose. an innovative.multi-ste. cluste.ing proce.ure.to se.me.t custome.s base. on load-shape.patte.ns at the.daily and intra-daily time.*** me.e. data is split be.we.n daily and hourly normalize. time.se.ie. to asse.s monthly,we.kly,daily,and hourly se.sonality patte.ns *** dime.sionality re.uction implicit in the.splitting allows a dire.t approach to cluste.ing raw daily e.e.gy time.se.ie. *** intraday cluste.ing proce.ure.se.ue.tially ide.tifie. re.re.e.tative.hourly day-unit profile. for e.ch custome. and the.e.tire.*** the.first time.a ste. function approach is applie. to re.uce.time.se.ie. *** attribute. e.be.de. in surve.s are.e.ploye. to build e.te.nal cluste.ing validation me.rics using Crame.’s V corre.ation factors and to ide.tify statistically significant de.e.minants of load-shape.in e.e.gy *** addition,a time.se.ie. fe.ture. e.gine.ring approach is use. to e.tract 16 re.e.ant de.and fle.ibility indicators that characte.ize.custome.s and corre.ponding cluste.s along four diffe.e.t axe.:available.e.e.gy(e.,Te.poral patte.ns(T),Consiste.cy(C),and Variability(V).The.me.hodology is imple.e.te. on a re.l-world e.e.tricity consumption datase. of 325 Small and Me.ium-size. e.te.prise.SMe.custome.s,ide.tifying 4 daily and 6 hourly e.sy-to-inte.pre.,we.l-de.ine. *** application of the.me.hodology include. se.e.ting ke. parame.e.s via grid se.rch and a thorough comparison of cluste.ing distance. and me.hods to e.sure.the.robustne.s of the.*** re.e.rch can te.t the.scalability of the.me.hodology to large. datase.s from various custome. se.me.ts(house.olds and large.comme.cial)and locations with diffe.e.t we.the. and socioe.onomic conditio

关键词： e.e.tric load cluste.ing load profiling smart me.e.s machine.le.rning data mining de.and fle.ibility de.and re.ponse

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The.e.fe.t of propagation de.ay on the.dynamic e.olution of the.Bitcoin blockchain

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Digital Communications and Ne.works 2020年第2期6卷 157-166页

作者： Moustapha ba MODAL’X(Laboratoire.de.Modélisation aléatoire.of Unive.sitéParis Nante.re.Paris X) MODAL’X is the Mathematics and Computer Sciences laboratory of UniversitéParis Nanterre(Paris X)ministerial label EA 3454UFR SEGMIdépartement Mathématiques-Informatique200 avenue de la République92000NanterreFrance

This pape. analyze. the.se.fish-mine.strate.y in the.Bitcoin blockchain introduce. in 2013 by *** and *** strate.y could be.use. by a colluding pool of mine.s to e.rn more.than the.r fair share.of the.mining re.e.ue.and in conse.ue.ce.to force.othe. hone.t mine.s to join the. to de.re.se.the.variance.of the.r re.e.ue. and make.the.r monthly re.e.ue. more.*** is a ve.y dange.ous dynamic that could allow the.rogue.pool of mine.s to go toward a majority by accumulating powe.s of ne.s adhe.e.ts and control the.e.tire.*** that the.propagation de.ay of information be.we.n any two mine.s in the.ne.work,which is not ne.ligible.and follows a normal distribution with me.n proportional to the.physical distance.be.we.n the.two mine.s,and a constant variance.inde.e.de.t of othe.s'de.ays,we.prove.that no guarante. can be.give. about the.succe.s or failure.of the.se.fish-mine.attack be.ause.of the.variability of information propagation in the.ne.work.

关键词： Blockchain Bitcoin Mining Se.fish-mine.attack Propagation de.ay of information

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P-wave.ve.ocity pre.iction in porous me.ium with liquid-pocke. patchy saturation

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Applie. Mathe.atics and Me.hanics(e.glish e.ition) 2015年第11期36卷 1427-1440页

作者： Jiawe. LIU We.tao SUN Jing ba Zhou Pe.-Yuan Ce.te. for Applie. Mathe.atics Tsinghua University De.artme.t of Computational Ge.physics Xi'an Jiaotong University

It be.ome. incre.singly cle.r that non-uniform distribution of immiscible.fluids in porous rock is particularly re.e.ant to se.smic wave.dispe.sion. White.propose. a patchy saturation mode. in 1975, in which sphe.ical gas pocke.s we.e.locate. at the.ce.te. of a liquid saturate. cube. For an e.tre.e.y light and compre.sible.inne. gas, the.physical prope.tie. can be.approximate. by a vacuum with White.s mode.. The.mode. succe.sfully analyze. the.dispe.sion phe.ome.a of a P-wave.ve.ocity in gas-wate.- saturate. rocks. In the.case.of liquid pocke. saturation, e.g., an oil-pocke. surrounde. by a wate. saturate. host matrix, the.light fluid-pocke. assumption is doubtful, and fe. works have.be.n re.orte. in White.s frame.ork. In this work, Poisson＇s ratio, the.bulk modulus, and the.e.fe.tive.de.sity of a dual-liquid saturate. me.ium are.formulate. for the.he.e.oge.e.us porous rocks containing liquid-pocke.s. The.analysis of the.diffe.e.ce.be.we.n the.ne.ly de.ive. bulk modulus and that of White.s mode. shows that the.e.fe.ts of liquid-pocke. saturation do not disappe.r unle.s the.porosity approache. ze.o. The.inne. pocke. fluid can no longe. be.ignore.. The.improve.e.ts of the.P-wave.ve.ocity pre.ictions are.illustrate. with two e.ample. take. from e.pe.ime.ts, i.e., the.P-wave.ve.ocity in the.sandstone.saturate. by oil and brine.and the.P-wave.ve.ocity for he.vy oils and stone. at diffe.e.t te.pe.ature..

关键词： White.s mode. porous me.ium P-wave.dispe.sion liquid pocke.

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A Unifie. Traje.tory Optimization Approach for Long-Te.m and Re.ctive.Motion Planning of Le.ge. Locomotion

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Journal of Bionic e.gine.ring 2023年第5期20卷 2108-2122页

作者： Yape.g Shi Bin Yu Kaixian ba Mantian Li School of Me.hanical e.gine.ring Yanshan UniversityNo.438 West Hebei AvenueQinhuangdao066004HebeiPeople’s Republic of China State.Ke. Laboratory of Robotics and Syste. Harbin Institute of TechnologyHarbin150001People’s Republic of China

This pape. propose. a unifie. traje.tory optimization approach that simultane.usly optimize. the.traje.tory of the.ce.te. of mass and footholds for le.ge. *** on a ge.e.ic point-mass mode.,the.approach is formulate. as a nonline.r optimization proble.,incorporating constraints such as robot kine.atics,dynamics,ground re.ction force.,obstacle.,and targe. *** unifie. optimization approach can be.applie. to both long-te.m motion planning and the.re.ctive.online.planning through the.use.of mode. pre.ictive.control,and it incorporate. ve.tor fie.d guidance.to conve.ge.to the.long-te.m planne. *** e.fe.tive.e.s of the.approach is de.onstrate. through simulations and physical e.pe.ime.ts,showing its ability to ge.e.ate.a varie.y of walking and jumping gaits,as we.l as transitions be.we.n the.,and to pe.form re.ctive.walking in obstructe. e.vironme.ts.

关键词： Le.ge. locomotion Motion planning Traje.tory optimization Bionic robot

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An e.d-to-e.d 3D se.smic simulation of unde.ground structure. due.to point dislocation source.by using an FK-Fe. hybrid approach

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Frontie.s of Structural and Civil e.gine.ring 2022年第12期16卷 1515-1529页

作者： Zhe.ning ba Jisai FU Zhihui ZHU Hao ZHONG State.Ke. Laboratory of Hydraulic e.gine.ring Simulation and Safe.y Tianjin UniversityTianjin 300072China School of Civil e.gine.ring Tianjin UniversityTianjin 300350China National e.gine.ring Re.e.rch Ce.te. of High Spe.d Railway Construction Te.hnology Central South UniversityChangsha 410075China School of Civil e.gine.ring Central South UniversityChangsha 410075China

base. on the.domain re.uction ide. and artificial boundary substructure.me.hod,this pape. propose. an FK-Fe. hybrid approach by inte.rating the.advantage. of FK and Fe.(i.e.,FK can e.ficie.tly ge.e.ate.high-fre.ue.cy thre. translational motion,while.Fe. has rich e.e.e.ts type. and constitutive.mode.s).An advantage.of this approach is that it re.lize. the.e.tire.proce.s simulation from point dislocation source.to unde.ground *** with the.plane.wave.fie.d input me.hod,the.FK-Fe. hybrid approach can re.le.t the.spatial variability of se.smic motion and the.influe.ce.of source.and propagation *** approach can provide.an e.fe.tive.solution for se.smic analysis of unde.ground structure. unde. sce.ario of e.rthquake.in re.ions whe.e.strong e.rthquake. may occur but are.not re.orde.,e.pe.ially whe. active.faults,crustal,and soil parame.e.s are.*** Daikai subway station as an e.ample.the.se.smic re.ponse.of the.unde.ground structure.is simulate. afte. ve.ifying the.corre.tne.s of the.approach and the.e.fe.ts of crustal ve.ocity structure.and source.parame.e.s on the.se.smic re.ponse.of Daikai station are.*** this e.ample.the.influe.ce.of ve.ocity structure.on the.maximum inte.laye. displace.e.t angle.of unde.ground structure.is 96.5%and the.change.of source.parame.e.s can le.d to the.change.of structural failure.dire.tion.

关键词： source.to-structure.simulation FK-Fe. hybrid approach unde.ground structure. point dislocation source

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Re.ative.Die.e.tric Pe.mittivity Variations during Compaction as a Me.n of Compaction Quality Control: Case.Study on Late.ite.Sample. from Se.e.al

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Inte.national Journal of Ge.scie.ce. 2023年第2期14卷 238-250页

作者： Mapathé Ndiaye.Makhaly ba Te.phile.Kie.dre.e.go Linda e. Gaffo Foudjo Laboratoire.de.Mécanique.e. de.Modélisation Université de Thiès Sénégal

This study e.plore. an alte.native.to the.classical use.of dire.t me.hods, as wate. conte.t and dry de.sity me.sure.e.ts, for compaction quality control. For this purpose. the.die.e.tric prope.tie. of late.itic mate.ials are.de.e.mine. by radar me.hod and are.compare. with the.pe.mittivity de.e.mine. from the.Topp formula and from the.CRIM mode.. This approach allowe. to e.tablish a re.ationship be.we.n the.ge.te.hnical prope.tie. de.e.mine. during compaction such as dry de.sity, wate. conte.t or porosity with die.e.tric pe.mittivity. The.obtaine. re.ults made.it possible.to de.e.mine.an optimum die.e.tric pe.mittivity corre.ponding to the.optimum dry de.sity and the.optimum wate. conte.t that could be.use. for non-de.tructive.in situ compaction te.ting. Such an approach should improve.the.imple.e.tation and e.fe.tive.e.s of in situ compaction quality control of ge.te.hnical infrastructure..

关键词： Late.ite Proctor Wate. Conte.t Dry De.sity Die.e.tric Pe.mittivity

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Discove.y and de.e.opme.t of synthe.ic tricyclic pyrroloquinone.（TPQ） alkaloid analogs for human cance. the.apy

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Frontie.s of Che.ical Scie.ce.and e.gine.ring 2016年第1期10卷 1-15页

作者： We. Wang Bhavitavya Nijampatnam Sadanandan e. Ve.u Ruiwe. Zhang De.artme.t of Pharmace.tical Scie.ce. School of Pharmacy Texas Tech University Health Sciences Center Amarillo TX 79106 USA Cance. Biology Ce.te. School of Pharmacy Texas Tech University Health Sciences Center Amarillo TX 79106 USA De.artme.t of Che.istry University of Alabama at Birmingham Birmingham AL 35294 USA

Natural products and the.r de.ivative. re.re. se.t a rich source.for the.discove.y and de.e.opme.t of ne. cance. the.ape.tic drugs. Bioactive.compone.ts de.ive. from natural source. including marine.compounds have.be.n shown to be.e.fe.tive.age.ts in the.clinic or in pre.linical se.tings. In the.pre.e.t re.ie., we.pre.e.t a story of discove.y, synthe.is and e.aluation of thre. synthe.ic tricyclic pyrroloquinone.（TPQ） alkaloid analogs as cance. the.ape.tic age.ts. Che.ical synthe.is of the.e.compounds （ba-TPQ, Tba-TPQ, and TCba-TPQ） has be.n accomplishe. and the.me.hanisms of action （MOA） and structure.activity re.ationships （SAR） have.be.n inve.tigate.. In the.past, the.comple.ity of che.ical synthe.is and the.lack of we.l-de.ine. MOA have.dampe.e. the.e.thusiasm for the.de.e.opme.t of some.makaluvamine.. Re.e.t discove.y of nove. mole.ular targe.s for the.e.alkaloids （unre.ate. to inhibition of Topoisome.ase.II） warrant furthe. conside.ation as clinical candidate. in the.future. In addition to the.e.tablishme.t of nove. synthe.ic approache. and de.onstration of in vitro and in vivo anticance. activitie., we.have.succe.sfully de.onstrate. that the.e.makaluvamine. attack se.e.al ke. mole.ular targe.s, including the.MDM2-p53 pathway, providing ample.opportunitie. of modulating the.compound structure.base. on SAR and the.use.of such compounds in combination the.apy in the.future.

关键词： synthe.is marine.drugs tricyclic pyrroloqui- none.alkaloid cance. the.apy MDM2 p53

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Optimization of antioxidant activity by re.ponse.surface.me.hodology in hydrolysate. of je.lyfish(Rhopile.a e.cule.tum) umbre.la collage.

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Journal of Zhe.iang Unive.sity-Scie.ce.B(Biome.icine.& Biote.hnology) 2009年第8期10卷 572-579页

作者： Yong-liang ZHUANG Xue.ZHAO ba-fang LI Colle.e.of Food Scie.ce.and e.gine.ring Ocean University of China Qingdao 266003 China

To optimize.the.hydrolysis conditions to pre.are.hydrolysate. of je.lyfish umbre.la collage. with the.highe.t hydroxyl radical scave.ging activity, collage. e.tracte. from je.lyfish umbre.la was hydrolyze. with trypsin, and re.ponse.surface.me.hodology （RSM） was applie.. The.optimum conditions obtaine. from e.pe.ime.ts we.e.pH 7.75, te.pe.ature.（T） 48.77 ℃, and e.zyme.to-substrate.ratio （[e./[S]） 3.50%. The.analysis of variance.in RSM showe. that pH and [e./[S] we.e.important factors that significantly affe.te. the.proce.s （P〈0.05 and P〈0.01, re.pe.tive.y）. The.hydrolysate. of je.lyfish umbre.la collage. we.e.fractionate. by high pe.formance.liquid chromatography （HPLC）, and thre. fractions （HF-1〉3000 Da, 1000 Da〈HF-2〈3000 Da, and HF-3〈1000 Da） we.e.colle.te.. The.HF-2 fraction had the.highe.t hydroxyl radical scave.ging activity with the.highe.t yie.d compare. with the.othe. two fractions. Furthe.more. HF-2 also showe. the.stronge.t Cu^2＋-che.ating ability and the.be.t tyrosinase.inhibitory activity.

关键词： Je.lyfish umbre.la collage. Hydrolysis Antioxidant activity Re.ponse.surface.me.hodology (RSM)

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Trace.e.e.e.t ge.che.istry and te.tonic characte.ization of the.granulite.facie. rocks from Southwe.t Obudu Plate.u,southe.ste.n Nige.ia

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Chine.e.Journal Of Ge.che.istry 2009年第3期28卷 248-257页

作者： e.e.e.e. Ukwang barth N. e.wue.e De.artme.t of Ge.logy P.M.B. 1115CalabarNigeria

The.trace.e.e.e.ts characte.istics of the.migmatitic gne.sse. (biotite.garne.and hornble.de.biotite., granulite.facie. rocks (charnockitic gne.sse.) and me.a-pe.idotite.in the.are. of Southwe.t Obudu Plate.u indicate.that the.are. e.hibits a high de.re. of ge.che.ical variability. Compatible.trace.e.e.e.ts (Ni and Cr) are.comparative.y high in the.granulite.facie. rocks and me.a-pe.idotite. Ni range. from 28×10-6 to 266×10-6 whilst Cr range. from 62×10-6 to 481×10-6 for the.granulite.facie. rocks (charnockitic gne.sse.), and for the.me.a-pe.idotite.Ni varie. be.we.n 2045×10-6 and 2060×10-6. Incompatible.trace.e.e.e.ts show a highe. variability in the.e.rocks. The.rocks in the.are. of Southwe.t Obudu Plate.u ge.e.ally are.characte.ize. by the.high conce.trations of ba, Ce. Sr, Rb, Ga, Ni, Cr, Co, Zr, Pr and mode.ate.conce.trations of Cu, Sm and Th. The.available.data show that the.charnockitic gne.sse. are.of lowe. crustal origin. The.e.richme.t of the.me.a-pe.idotite.in compatible.trace.e.e.e.ts sugge.ts the.primitive.mantle.would be.the.source.re.ion, with slight contamination during asce.t. The.e.dive.se.origins collaborate.the.te.tonic se.ting of the.are. as shown by discrimination diagrams. The.dive.se.te.tonic se.tings range.from arc to collisional. Alkaline.to sub-alkaline.magmatism in the.are. was probably conte.porane.us with the.te.tonic e.e.ts that occurre. in the.are. during the.Prote.ozoic.

关键词：元素地球化学麻粒岩相高原地区岩石西南尼日利亚构造特征东南部

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A simulation-base. software.to support the.re.l-time.ope.ational parame.e.s se.e.tion of tunne. boring machine.

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Unde.ground Space 2024年第1期14卷 176-196页

作者： Yaman Ze.daki ba Trung Cao Abdullah Alsahly Ste.fe. Fre.tag Gunthe. Me.chke Institute.for Structural Me.hanics Ruhr University BochumBochum 44801Germany Institute.for Structural Analysis Karlsruhe Institute of TechnologyKarlsruhe 76131Germany

With the.fact that the.main ope.ational parame.e.s of the.construction proce.s in me.hanize. tunne.ing are.curre.tly se.e.te. base. on monitoring data and e.gine.ring e.pe.ie.ce.without e.ploiting the.advantage. of compute. me.hods,the.focus of this work is to de.e.op a simulation-base. re.l-time.assistant syste. to support the.se.e.tion of ope.ational *** choice.of an appropriate.se. of the.e.parame.e.s(i.e.,the.face.support pre.sure.the.grouting pre.sure.and the.advance.spe.d)during the.ope.ation of tunne. boring machine.(TBM)is de.e.mine. by e.aluating diffe.e.t tunne.ing-induce. soil-structure.inte.actions such as the.surface.se.tle.e.t,the.associate. risks on e.isting structure. and the.tunne. lining *** e.aluate.soil-structure.be.avior,an advance. proce.s-orie.te. nume.ical simulation mode. base. on the.finite.ce.l me.hod is *** e.able.the.re.l-time.pre.iction capability of the.simulation mode. for a practical application during the.advance.e.t of TBMs,surrogate.mode.s base. on the.Prope. Orthogonal De.omposition and Radial basis Functions(POD-RBF)are.*** propose. approach is de.onstrate. through se.e.al synthe.ic nume.ical e.ample. inspire. by the.data of re.l tunne. *** de.e.ope. me.hods are.inte.rate. into a use.-frie.dly application calle. SMART to se.ve.as a support platform for tunne. e.gine.rs at construction *** to e.ch use. adjustme.t of the.input parame.e.s,i.e.,e.ch TBM driving sce.ario,approximate.y two million outputs of soil-structure.inte.actions are.quickly pre.icte. and visualize. in se.onds,which can provide.the.site.e.gine.rs with a rough e.timation of the.impacts of the.chose. sce.ario on structural re.ponse. of the.tunne. and above.ground structure..

关键词： Nume.ical simulation Surrogate.mode. Re.l-time.pre.iction Prope. orthogonal de.omposition Radial basis functions TBM ope.ation Smart construction

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