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Inte.active.antimicrobial and toxicity profile. of Pittosporum angustifolium Lodd. e.tracts with conve.tional antimicrobials

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Journal of Inte.rative.Me.icine 2019年第4期17卷 261-272页

作者： Baxte. Blonk Ian e. Cock School of e.vironme.t and Scie.ce Griffith University Nathan Queensland 4111 Australia e.vironme.tal Future. Re.e.rch Institute Nathan Campus Griffith University Nathan Queensland 4111 Australia

Obje.tive. Pittosporum angustifolium Lodd. is use. to tre.t a varie.y of pathoge.ic dise.se. and inflamma-tion by Australian aborigine.. Practitione.s of comple.e.tary me.icine.fre.ue.tly use.he.bal me.icine. concurre.tly with conve.tional antibiotics. The.e.is a ne.d to e.aluate.the.r e.fe.ts in combination. Me.hods: The.bacte.ial growth inhibitory activity of P. angustifolium le.f e.tracts was asse.se. against a pane. of pathoge.ic trigge.s of some.autoimmune.dise.se. by standard disc diffusion and liquid dilution minimum inhibitory conce.tration (MIC) me.hods. Combinational e.fe.ts be.we.n the.e.tracts and con-ve.tional antimicrobials we.e.classifie. using the.sum of the.fractional inhibitory conce.tration. Syne.gistic inte.actions we.e.furthe. asse.se. across a range.of ratios by isobologram analysis. The.tox-icity of the.individual sample. and combinations was e.aluate. by Ane.ia le.hality and 3-(4,5-dime.hyl thiazol-2-yl)-5-(3-carboxyme.hoxyphe.yl)-2-(4-sulfophe.yl)-2H-te.razolium) human de.mal fibroblast ce.l viability assays. Re.ults: P. angustifolium le.f e.tracts strongly inhibite. the.growth of se.e.al bacte.ial trigge.s of autoim-mune.dise.se.. The.me.hanolic, aque.us and e.hyl ace.ate.e.tracts we.e.pwrticularly good inhibitors of Prote.s mirabilis and Kle.sie.la pne.monia growth (MIC=26 and 57 ng/mL re.pe.tive.y). Some.combinations of the.e.tracts and conve.tional antibiotics signiflcantlv pote.tiate. the.combine. inhibitory activity compare. to the.individual compone.ts. Of the.250 combinations studie., approximate.y 0.02% showe. syne.gistic inte.actions, 49.6% we.e.additive. 46.8% showe. indiffe.e.t inte.actions and antago-nism occurre. in only 0.02% of the.combinations. Inte.e.tingly, all of the.syne.gistic and antagonistic combinations containe. te.racycline.as the.r antibiotic compone.t. Conclusion: P. angustifolium le.f e.tracts inhibit the.growth of pathoge.ic trigge.s of some.autoimmune.dise.se.. Some.e.tracts also pote.tiate. the.activity of co

关键词： Me.icinal plants Conve.tional antimicrobials Syne.gy Inte.action Toxicity

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e.onomic De.e.opme.t through Me.icinal and Aromatic Plants(MAPs) Cultivation in Hindu Kush Himalaya Mountains of District Swat, Pakistan

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Journal of Mountain Scie.ce 2015年第5期12卷 1292-1301页

作者： Hassan SHe. Mary e. BARKWORTH Ce.te. for Plant Scie.ce. and Biodive.sity University of Swat Inte.mountain He.barium Department of Biology Utah State University

Pove.ty is pe.vasive.in the.Swat Valle. in northwe.te.n Pakistan, and most pe.ple.survive.by farming small landholdings. Howe.e., many supple.e.t the.r me.ge. subsiste.ce.e.rnings by colle.ting and se.ling plant mate.ial for use.in he.bal me.icine. This mate.ial is wild-harve.te., but colle.tors se.m not to fully appre.iate.the.pote.tial value.of the.plant mate.ial the. colle.t nor the.longte.m impact the.r colle.tion has on local plant populations. A mode. proje.t supporte. by the.Inte.national Food Policy Re.e.rch Institute.IFPRI)pe.suade. small-scale.farme.s in four diffe.e.t village. to use.some.of the.r land for cultivating traditionally wild-harve.te. spe.ie. of me.icinal and aromatic plants(MAPs) with high marke. value. The.farme.s we.e.provide. se.ds or rhizome. of five.MAPs and aske. to monitor the.r ge.mination and growth on 25 m2 plots during a 12 month pe.iod. At the.e.d of the.study, growth and yie.d data from the.four localitie. we.e.compare. and e.onomic analyse. conducte. to de.e.mine.the.profitability of the.spe.ie. base. on yie.ds, pre.ailing marke. price., and costs of production. Five.of the.cultivate. spe.ie. we.e.subse.ue.tly marke.e. and the.r value.e.aluate.:Se.amum indicum, Linum usitatissimum, Ocimum basilicum, Nige.la sativa and Viola pilosa. The.MAPs V. pilosa and O. basilicum we.e.the.most profitable.whe.e.s Nige.la sativa was the.le.st profitable.be.ause.of its low ge.mination rate. The.ne. income.from all but Nige.la was highe. than that would have.be.n e.rne. by planting the.same.are. with the.pre.ominant ce.e.ls or tomatoe.. In addition to de.onstrating the.fe.sibility and financial be.e.its of cultivating MAPs as a cash crop, this mode. study ide.tifie. a numbe. of additional ste.s that would incre.se.the.be.e.its of MAPs cultivation in this are..A combination of spe.ialize. e.ucation, marke. infrastructure.de.e.opme.t and a small loans program would e.able.farme.s to incre.se.the.r agricultural income.without damaging the.are.'s pl

关键词： Biological dive.sity Me.icinal plant Aromatic plant Agriculture.productivity Traditionalcrops e.onomic analysis Himalaya Mountains

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DNA alkylation promote. by an e.e.tron-rich quinone.me.hide. inte.me.iate

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Frontie.s of Che.ical Scie.ce.and e.gine.ring 2016年第2期10卷 213-221页

作者： Che.gyun Huang Ste.e. e. Rokita De.artme.t of Che.istry and Bioche.istry University of Maryland College Park MD 20742 USA Sichuan Institute.of Ge.logical e.gine.ring Inve.tigation Chengdu 610072 China De.artme.t of Che.istry Johns Hopkins University Baltimore MD 21218 USA

Biological application of conjugate. de.ive. from oligonucle.tide. and quinone.me.hide. have.pre. viously be.n limite. by the.slow e.change.of the.r covale.t se.f-adducts and subse.ue.t alkylation of targe. nucle.c acids. To e.hance.the.rate. of the.e.proce.se., a ne. quinone.me.hide.pre.ursor with an e.e.tron donating substitue.t has be.n pre.are.. Additionally, this substi- tue.t has be.n place. para to the.nasce.t e.o-me.hyle.e.group of the.quinone.me.hide.for maximum e.fe.t. A conjugate.made.from this pre.ursor and a 5＇-aminohe.- yloligonucle.tide.acce.e.ate. formation of its re.e.sible.se.f-adduct and alkylation of its comple.e.tary DNA as pre.icte. from prior mode. studie..

关键词： quione.me.hide DNA alkylation re.e.sible.covale.t re.ction bioconjugation targe.-dire.te. modification of nucle.c acids

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A Prime.Submodule.Principle

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Alge.ra Colloquium 2014年第4期21卷 697-710页

作者： R. Ne.ooe. e. Rostami De.artme.t of Mathe.atics Shahid Bahonar University of Kerman Kerman Iran

In this pape., we.e.te.d the.conce.t of Ako and Ol~ familie. to submodule., study the.be.avior of the.e.te.de. prime.submodule.principle.and use.the.e.conce.ts to give.ne. proofs of some.familiar the.re.s.

关键词： prime.submodule. multiplication module. Ako and Oka familie. stronglyAko and strongly Oka

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Re.ucing the.loss of ge.e.ic dive.sity associate. with assiste. colonization-like.introductions of animals

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Curre.t Zoology 2015年第5期61卷 827-834页

作者： Jaana Ke.KONe. Jon e. BROMMe. De.artme.t of Bioscie.ce. University of Helsinki Helsinki Finland De.artme.t of Biology University of Turku Turku Finland

Translocations, e.pe.ially assiste. colonizations, of animals are.incre.singly use. as a conse.vation manage.e.t tool. In many case., howe.e., limite. funding and othe. logistic challe.ge. limit the.numbe. of individuals available.for transloe.tion. In conse.vation ge.e.ics, small populations are.pre.icte. to rapidly lose.ge.e.ic dive.sity which can de.e.iorate.population survival. Thus, how worrie. should we.be.about the.loss of ge.e.ic dive.sity whe. introducing small, isolate. populations？ Historical spe.ie. introductions provide.a me.ns to asse.s the.e.issue.. He.e.we.re.ie. 13 studie. of ＂assiste. colonization-like. introductions of animals, whe.e.only a small known numbe. of founde.s e.tablishe. an isolate. population without se.ondary contact to the.source.population. We.te.t which factors could be.important in re.aining ge.e.ic dive.sity in the.e.case.. In many case., loss in he.e.ozygosity （-12.1%） was de.e.te., and more.se.iously the.loss in alle.ic richne.s （-27.8 %）. Numbe. of founde.s se.me. to have.an e.fe.t but it also indicate. that high population growth rate.could he.p to re.ain ge.e.ic dive.sity, i.e. future.manage.e.t actions could be.e.fe.tive.e.e. with a limite. numbe. of founde.s if population growth would be.e.hance.. On the.contrary, translocate. organisms with longe. ge.e.ation time. did not se.m to re.ain more.ge.e.ic dive.sity. We.advocate.that, whe.e.possible. future.studie. on translocate. animals should re.ort the.loss of ge.e.ic dive.sity （both he.e.ozygosity and alle.ic richne.s）, which is e.se.tial for me.a-analyse. like.this one.for de.pe.ing our unde.standing of the.ge.e.ic conse.ue.ce. of assiste. colonization, and justifying manage.e.t de.isions [Curre.t Zoology 61 （5）： 827-834, 2015].

关键词： Introduce. spe.ie. Loss of ge.e.ic dive.sity Numbe. of founde.s Conse.vation manage.e.t Population growth rate Ge.e.ation time

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Propose. GSSP for the.base.of Cambrian Stage.9,coinciding with the.first appe.rance.of Agnostote. orie.talis, at Duibian, Zhe.iang, China

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Scie.ce.China e.rth Scie.ce. 2009年第4期52卷 434-451页

作者： Lore. e. BABCOCK Gabrie.la BAGNOLI School of e.rth Scie.ce. The Ohio State University De.artme.t of e.rth Scie.ce. of Pisa Unive.sity

e.pose. in natural outcrops ne.r the.Duibian Village. Jiangshan County, Zhe.iang Province. China, the.Duibian B se.tion is propose. as the.boundary stratotype.for the.base.of an unname. stage.te.me. provisionally Cambrian Stage.9. The.propose. position of the.GSSP is 108.12 m above.the.base.of the.Huayansi Formation, at a horizon coinciding with the.first appe.rance.of the.cosmopolitan agnostoid trilobite.Agnostote. orie.talis. This horizon coincide. also with the.first appe.rance.of the.cosmopoli-tan polyme.id trilobite.Irvinge.la angustilimbata. The.se.tion fulfills all the.re.uire.e.ts for a GSSP, and the.horizon can be.constraine. not only by the.primary stratigraphic marke. (A. orie.talis) but also with se.ondary biostratigraphic, che.ostratigraphic, and se.ue.ce.stratigraphic corre.ation tools. The.first appe.rance.of A. orie.talis is one.of the.most re.dily re.ognizable.le.e.s in Cambrian, and can be.corre.ate. with pre.ision to all pale.contine.ts.

关键词： Cambrian GSSP FAD of Agnostote. orie.talis China chronostratigraphy

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On Quasi-Re.uce. Quadratic Forms

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Acta Mathe.atica Sinica,e.glish Se.ie. 2010年第8期26卷 1425-1448页

作者： e. DUBOIS C. Le.e.QUe e.ge.e.Dubois UMR 6138 CNRS Dep. de mathematiques et mecanique BP 5186 U. de Caen Basse-Normandie 14032 Caen France Claude.Le.e.que CICMA et Departement de mathematiques et de statistique U. Laval Quebec P. Qudbec Canada G1K 7P4

With the.he.p of continue. fractions, we.plan to list all the.e.e.e.ts of the.se. Q△ = {aX2 ＋ bXY ＋ cY2 ： a,b, c ∈Z, b2 - 4ac = △ with 0 ≤ b 〈 √△}of quasi-re.uce. quadratic forms of fundame.tal discriminant △. As a matte. of fact, we.show that for e.ch re.uce. quadratic form f = aX2 ＋ bXY ＋ cY2 = （a, b, c） of discriminant △〉0（and of sign σ（f） e.ual to the.sign of a）, the.quadratic forms associate. with f and de.ine. by {〈a＋bu＋cu2,b＋2cu.c〉},with 1≤σ（f）u≤b/2｜c｜（whe.e.e. the. e.ist）, 〈c,-b-2cu,a＋bu＋cu2〉 with b/2｜c｜≤σ（f）u≤[w（f）]=[b＋√△/2｜c｜], are.all diffe.e.t from one.anothe. and build a se. I（f） whose.cardinality is #I（f）={1＋[ω（f）],whe.（2c）｜b,[ω（f）],whe. （2c）｜b. If f and g are.two diffe.e.t re.uce. quadratic forms, we.show that I（f） ∩ I（g） = Ф. Our main re.ult is that the.se. Q△ is give. by the.disjoint union of all I（f） with f running through the.se. of re.uce. quadratic forms of discriminant △〉0. This allows us to de.uce.a formula for #（Q△） involving sums of partial quotie.ts of ce.tain continue. fractions.

关键词： Quadratic forms re.uce. forms e.uivale.ce.of forms class numbe.s quadratic fie.ds,continue. fractions

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AMS studie. on a 450 km long 2216 Ma dyke.from Dharwar craton, India:Implications to magma flow

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Ge.scie.ce.Frontie.s 2019年第5期10卷 1931-1939页

作者： e. Nagaraju V. Parashuramulu Pale.magne.ism Division CSIR-National Geophysical Research InstituteUppal RoadHyderabad-500007India TSMS Jr. Colle.e BaswapurPulkalSangareddy DistrictTelanganaIndia

Anisotropy of magne.ic susce.tibility (AMS) studie. we.e.carrie. out on a pre.ise.y date. (2216.0 ± 0.9 Ma),450 km long Ne. striking dyke.in the.Dharwar Craton,to de.e.mine.the.magma flow dire.tion along the.dyke.*** orde. to use.the.imbrication of the.magne.ic foliation,forty e.ght sample. we.e.colle.te. from 13 locations along the.le.gth of the.*** studie. show that AMS fabric is dominate. by me.ium graine. inte.stitial Ti-poor multidomain *** corre.te. anisotropy de.re. (Pj) of the.sample. was found to be.low to mode.ate.be.we.n 1.007 and 1.072,which indicate. primary magne.ic *** magne.ic e.lipsoid is e.the. triaxial,prolate.or oblate.and cle.rly de.ine. normal,inte.me.iate.and inve.se.magne.ic fabrics re.ate. to magma flow during the.dyke.*** maximum susce.tibility axe. (Kmax) of the.AMS te.sor of the.dyke.is pre.ominantly incline. at low angle. (e.atic variation in de.th along the.Ne. profile.indicating sub-horizontal flow e.e. at mid crustal le.e.s which could probably be.gove.ne. by location of the.focal re.ion of the.magma source.(mantle.plume.),flow dynamics toge.he. with the.compre.sive.stre.se. e.e.te. by the.ove.lying crust.

关键词： Anisotropy of magne.ic susce.tibility Dharwar craton Dyke swarms

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The.lacustrine.se.ime.tary re.ords of coal-burning atmosphe.ic pollution

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Scie.ce.China e.rth Scie.ce. 2005年第10期48卷 1740-1746页

作者： e. Appe. V. Hoffmann Institut für Ge.wisse.schafte. Universitt Tübingen 72076 Tübingen GermanyInstitut für Geowissenschaften Universitt Tübingen 72076 Tübingen Germany

Base. on the.studie. on diatom, ostracods and magne.ism on a core.acquire. from lacustrine.se.ime.ts, as we.l as corre.ation analysis be.we.n conce.tration of acid diatom and the.instantane.us lowe.t pH value. the.proce.se. of e.vironme.t e.olution in Lake.Yangzonghai we.e.re.onstructe.. The.lacustrine.e.vironme.t was favorable.in the.1950s, and be.an to be.pollute. by a coal-burning powe. plant since.1960. During 1965―1980, the.instantane.us lowe.t pH value.of lake.wate. de.re.se. to 5―6 whe. he.vily pollute.. The.e.was a de.re.se.tre.d in the.pollution from 1983 to 1999, but coal-burning atmosphe.ic pollution was still a main proble. for e.vironme.tal re.rie.ing. As acid pre.ipitate., acid-tole.ant spe.ie. ove.spre.d, and she.lfish disappe.re., as we.l as fe.romagne.ic particulate. dissolve. be.ause.of the.conse.ue.t change.of pH-e. value. in the.inte.face.of wate. and soil, which re.ults in the.change.of e.vironme.tal proxie. ve.sus de.th. Thus, the.e.vironme.tal e.olution of Lake.Yangzonghai is re.onstructe. in this pape. base. on the.infe.e.ce. me.tione. above.

关键词： atmosphe.ic pollution, proxie., e.vironme.tal re.onstruction, lacustrine se.ime.t, Lake Yangzonghai.

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Drag re.uction be.avior of hydrolyze. polyacrylamide.xanthan gum mixe. polyme. solutions

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Pe.role.m Scie.ce 2017年第2期14卷 412-423页

作者： Me.di Habibpour Pe.e. e. Clark School of Che.ical e.gine.ring Oklahoma State University Stillwater OK 74078 USA

Partially hydrolyze. polyacrylamide.HPAM）as the.main compone.t of slickwate. fracturing fluid is a she.r-se.sitive.polyme.,which suffe.s from me.hanical de.radation at turbule.t flow *** diffe.e.t conce.trations of HPAM as we.l as mixture. of polyacrylamide.xanthan gum we.e.pre.are. to inve.tigate.the.possibility of improving she.r stability of *** re.uction（DR）me.sure.e.ts we.e.pe.forme. in a close. flow *** HPAM solutions,the.e.te.t of DR incre.se. from 30%to67%with incre.sing HPAM conce.tration from 100 to1000 *** the.HPAM solutions suffe.e. from me.hanical de.radation and loss of DR e.ficie.cy ove. the.she.ring *** indicate. that the.re.istance.to she.r de.radation incre.se. with incre.sing polyme. *** e.ficie.cy of 600 wppm xanthan gum（XG）was 38%,indicating that XG was not as good a drag re.uce. as *** with only 6%DR de.line.XG solution e.hibite. a be.te. she.r stability compare. to HPAM *** HPAM/XG solutions initially e.hibite. gre.te. DR（40%and 55%）compare. to XG,but due.to she.r de.radation,DR%droppe. for HPAM/XG *** to 200 wppm HPAM solution,addition of XG did not improve.the.drag re.uction e.ficie.cy of HPAM/XG mixe. solutions though XG slightly improve. the.re.istance.against me.hanical de.radation in HPAM/XG mixe. polyme. solutions.

关键词： Slickwate. Polyacrylamide Xanthan gum Drag re.uction She.r stability

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