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Non-alcoholic fatty liver disease in the Philippines:Comparable with other nations?

World Journal of Gastroenterology 2008年第6期14卷 913-917页

作者： Mark Anthony A De Lusong e labio L Daez V Gloria Philippine General Hospital Manila Philippines

AIM: To evaluate the prevalence and determined the common characteristics of patients diagnosed with non- alcoholic fatty liver disease (NAFLD) at the Philippine General Hospital, Manila, from January 1999 to December 2004. MeTHODS: NAFLD was diagnosed in 134 from a total of 1102 patients, based on clinical, ultrasonographic and/or histopathological findings. Patients with conditions associated with secondary NAFLD were excluded. Chart review was done to note demographics, co- morbid illnesses, physical characteristics, hepatomegaly, aspartate/alanine aminotransferase (AST/ALT) levels, albumin, lipid levels, alkaline phosphatase, prothrombin time, and partial thromboplastin time. Data obtained were analyzed using the statistical program SPSS version 10. ReSULTS: Of the 134 patients included, 71% were female and 29% male. Mean patient age was 42.2 years. Sixty percent of patients were obese, 56% had hepatomegaly, and 69% had diabetes. AST levels were elevated in 45% of subjects and ALT levels in 64%. CONCLUSION: The prevalence of NAFLD at our institution was 12.2%. Patients diagnosed appear to be younger in age in contrast to previous studies. Female sex, obesity, elevated liver enzymes, and diabetes were characteristic features of our NAFLD patients, which is comparable to previous studies from other countries.

关键词： Fatty liver Obesity Non-alcoholic fatty liver disease Diabetes Philippines

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Hepatitis B infection among adults in the philippines:A national seroprevalence study

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World Journal of Hepatology 2013年第4期5卷 214-219页

作者： Stephen N Wong Janus P Ong Madalinee eternity D labio Oscar T Cabahug Maria Lourdes O Daez erlinda V Valdellon Jose D Sollano Jr Marilyn O Arguillas Section of Gastroenterology University of Santo Tomas HospitalManila 1008Philippines Section of Gastroenterology University of the Philippines-Philippine General HospitalManila 1000Philippines Center for Liver Disease Management and Transplantation The Medical CityPasig 1605Philippines College of Medicine University of the East Ramon Magsaysay Memorial Medical CenterQuezon City 1113Philippines Department of Internal Medicine Davao Doctors HospitalDavao 8000Philippines

AIM:To determine the prevalence of hepatitis B surface antigen(HBsAg)seropositivity among adult ***:Testing for HBsAg was performed on serum samples from persons aged ≥ 20 years old who participated in the National Nutrition and Health Survey(NNHeS)conducted in *** on age,sex,marital status,educational attainment,employment status,and income were *** this study,marital status was classified as never married or otherwise(i.e.,married,divorced,separated,widowed);educational attainment was classified as high school graduate or below or at least some tertiary education;and employment status was classified as currently employed or currently *** income was divided into 4 quartiles in Philippine pesos(PhP):Q1,≤ PhP 53064;Q2,PhP 53065-92192;Q3,PhP 92193-173387;and Q4,≥ PhP *** estimates were weighted so that they represented the general *** and demographic factors were correlated with HBsAg *** analysis was used to determine independent predictors of HBsAg ***:A total of 2150 randomly selected adults,20 years and over,out of the 4753 adult participants of NNHeS were tested for *** HBsAg seroprevalence was 16.7%(95%CI:14.3%-19.1%),which corresponded to an estimated 7278968 persons infected with hepatitis *** was no significant difference between males and females(17.5% vs 16.0%;P = 0.555).This corresponded to an estimated 3721775 men and 3557193 women infected with hepatitis *** HBsAg seroprevalence peaked at age 20-39 years old,with declining prevalence in the older age *** only independent predictor of HBsAg seropositivity was the annual income,with persons in the highest income quartile being less likely to be HBsAg positive(age-adjusted OR = 0.51;95%CI:0.30-0.86)compared to subjects in the lowest income ***,marital status,educational attainment,and employment status were not found to be independent predictors of HBsAg serop

关键词： Prevalence Hepatitis B Survey Philippines Asia

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