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Fair-news: Digital Journalism Model to Prevent Information Pollution and Manipulation

Computers, Materials & Continua 2023年第6期75卷 6059-6082页

作者： Savas Takan duygu ergün Gökmen Katipoglu Department of Artificial Intelligence and Data Engineering Ankara UniversityAnkara06830Turkey Faculty of Fine Arts Design&Architecture Fine Arts and Elective CoursesAtılım UniversityAnkara06830Turkey Department of Computer Engineering Kafkas UniversityKars36100Turkey

As digital data circulation increases,information pollution and manipulation in journalism have become more *** this study,a new digital journalism model is designed to contribute to the solution of the main current problems,such as information pollution,manipulation,and account-ability in digital *** model uses blockchain technology due to its transparency,immutability,and ***,it is tough to provide the mechanisms necessary for journalism,such as updating one piece of information,instantly updating all other information affected by the updated information,establishing logical relationships between news,making quick comparisons,sorting and indexing news,and keeping the changing informa-tion about the news in the system,with the blockchain data *** this reason,in our study,we have developed a new data structure that provides both the immutability,transparency and traceability properties of the blockchain and can support the communication mechanisms necessary for *** functionality of our proposed data structure is demonstrated in terms of communication mechanisms such as mutability,context,consistency,and reliability through example ***,our data structure is compared with the data structure of blockchain technology in terms of time,space,and maintenance ***,while the model size increases linearly in blockchain,the model’s size remains approximately constant since the structure we developed is *** this way,maintenance costs are *** our model also has an indexing mechanism,it reduces the linear time search complexity to logarithmic *** a result,the data structure we developed is found to have higher performance than blockchain in the journalism *** future studies,it is planned to test all aspects of the model with a pilot application,eliminate its shortcomings,and develop a holistic approach to the root causes of the problems in the journalism

关键词： Digital journalism data structure news-sharing platform verification mechanism distributed ledger new media information pollution and manipulation

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Role of alcohol in the regulation of iron metabolism

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World Journal of Gastroenterology 2007年第37期13卷 4924-4930页

作者： duygu Dee Harrison-Findik Division of Gastroenterology and Hepatology Department of Internal Medicine University of Nebraska Medical Center Omaha NE 681985820 United States

Patients with alcoholic liver disease frequently exhibit increased body iron stores, as reflected by elevated serum iron indices (transferrin saturation, ferritin) and hepatic iron concentration. Even mild to moderate alcohol consumption has been shown to increase the prevalence of iron overload. Moreover, increased hepatic iron content is associated with greater mortality from alcoholic cirrhosis, suggesting a pathogenic role for iron in alcoholic liver disease. Alcohol increases the severity of disease in patients with genetic hemochromatosis, an iron overload disorder common in the Caucasian population. Both iron and alcohol individually cause oxidative stress and lipid peroxidation, which culminates in liver injury. Despite these observations, the underlying mechanisms of iron accumulation and the source of the excess iron observed in alcoholic liver disease remain unclear. Over the last decade, several novel iron-regulatory proteins have been identified and these have greatly enhanced our understanding of iron metabolism. For example, hepcidin, a circulatory antimicrobial peptide synthesized by the hepatocytes of the liver is now known to play a central role in the regulation of iron homeostasis. This review attempts to describe the interaction of alcohol and iron-regulatory molecules. Understanding these molecular mechanisms is of considerable clinical importance because both alcoholic liver disease and genetic hemochromatosis are common diseases, in which alcohol and iron appear to act synergistically to cause liver injury.

关键词： Alcoholic liver disease C/EBP alpha Divalentmetal transporter 1 Ferroportin Hepcidin

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A broker-based semantic agent for discovering Semantic Web services through process similarity matching and equivalence considering quality of service

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Science China(Information Sciences) 2013年第1期56卷 18-41页

作者： ELK duygu EL Atilla Computer Engineering Department Istanbul Aydin University Electrical-Elecronics Engineering Department Aksaray University

The lack of semantic descriptions for "web service properties" makes it difficult to find suitable web *** solutions are mostly based on broker/mediator agent ***,these techniques are syntactical,rather than semantics *** article presents a semantic matching approach for discovering Semantic Web services through a broker-based semantic agent(BSA).The BSA includes knowledge-bases and several processing *** BSA’s knowledge-bases are concept,task,and process ontologies built to describe both functional and non-functional parameters of *** BSA executes semantic-based matching algorithms to discover similar services through the semantic matching step,process equivalence task,and matching of quality of service *** services are ranked by client preferences utilizing the semantic descriptions of available *** matchmaker studies are reviewed and compared with the *** of the BSA algorithm is compared with SAM using published data and an experimental *** results indicate that our approach is better and more effective in some respects.

关键词： Semantic Web Semantic Web services broker web applications ontologies semantic agents

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Unveiling the intricacies of irritable bowel syndrome

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World Journal of Gastroenterology 2024年第44期30卷 4763-4767页

作者： duygu Kirkik Sevgi Kalkanli Tas Department of Immunology University of Health SciencesHamidiye Medicine FacultyIstanbul 34668Türkiye Department of Medical Biology University of Health SciencesHamidiye Medicine FacultyIstanbul 34668Türkiye

Irritable bowel syndrome(IBS)remains a challenging condition both for patients and clinicians,characterized by its chronic nature and the elusive complexity of its underlying *** multifaceted relationship between the neuroendocrine axis,gut microbiota,and inflammatory response has emerged as a focal point in recent research,offering new insights into the pathophysiology of *** neuroendocrine axis plays a crucial role in maintaining the delicate balance between the brain and the gut,often referred to as the“gut-brain axis”.This bidirectional communication is essential for regulating gastrointestinal function,stress responses,and overall *** of this axis,as highlighted by elevated cortisol and serotonin levels in IBS patients,suggests that neuroendocrine imbalances may significantly contribute to the severity of gastrointestinal *** findings underscore the need for a broader understanding of how stress and emotional factors influence IBS,potentially guiding more effective,personalized treatment *** important is the role of the gut microbiota,a diverse and dynamic ecosystem that directly impacts gut *** dysbiosis disrupts gut function and appears to exacerbate the neuroendocrine and inflammatory *** findings align with the growing recognition that gut microbiota is a critical player in IBS,influencing both the disease's onset and progression.

关键词： Gastrointestinal symptoms Inflammatory response Intestinal microbiota Irritable bowel syndrome neuroendocrine axis

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Evaluating different levels of information on the calibration of building energy simulation models

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Building Simulation 2024年第4期17卷 657-676页

作者： Siyu Cheng Zeynep duygu Tekler Hongyuan Ji Wenxin Li Adrian Chong Department of the Built Environment College of Design and EngineeringNational University of Singapore4 Architecture DriveSingapore117566Singapore School of Civil Engineering and Architecture Chongqing University of Science and TechnologyChongqing401331China School of Energy and Environment Southeast UniversityNanjing210096China

A poorly calibrated model undermines confidence in the effectiveness of building energy simulation, impeding the widespread application of advanced energy conservation measures (ECMs). Striking a balance between information-gathering efforts and achieving sufficient model credibility is crucial but often obscured by ambiguities. To address this gap, we model and calibrate a test bed with different levels of information (LOI). Beginning with an initial model based on building geometry (LOI 1), we progressively introduce additional information, including nameplate information (LOI 2), envelope conductivity (LOI 3), zone infiltration rate (LOI 4), AHU fan power (LOI 5), and HVAC data (LOI 6). The models are evaluated for accuracy, consistency, and the robustness of their predictions. Our results indicate that adding more information for calibration leads to improved data fit. However, this improvement is not uniform across all observed outputs due to identifiability issues. Furthermore, for energy-saving analysis, adding more information can significantly affect the projected energy savings by up to two times. nevertheless, for ECM ranking, models that did not meet ASHRAE 14 accuracy thresholds can yield correct retrofit decisions. These findings underscore equifinality in modeling complex building systems. Clearly, predictive accuracy is not synonymous with model credibility. Therefore, to balance efforts in information-gathering and model reliability, it is crucial to (1) determine the minimum level of information required for calibration compatible with its intended purpose and (2) calibrate models with information closely linked to all outputs of interest, particularly when simultaneous accuracy for multiple outputs is necessary.

关键词： calibration building energy simulation(BES) energy conservation measure(ECM) level of information field measurements

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World Journal of Hepatology 2010年第8期2卷 302-310页

作者： duygu D Harrison-Findik Division of Gastroenterology and Hepatology Department of Internal MedicineUniversity of Nebraska Medical Center

The regulation of iron metabolism involves multiple organs including the duodenum,liver and bone *** recent discoveries of novel iron-regulatory proteins have brought the liver to the forefront of iron *** iron overload disorder,genetic hemochromatosis,is one of the most prevalent genetic diseases in individuals of Caucasian ***,patients with non-hemochromatotic liver diseases,such as alcoholic liver disease,chronic hepatitis C or nonalcoholic steatohepatitis,often exhibit elevated serum iron indices(ferritin,transferrin saturation)and mild to moderate hepatic iron *** data indicate significant differences between men and women regarding liver injury in patients with alcoholic liver disease,chronic hepatitis C or nonalcoholic *** penetrance of genetic hemochromatosis also varies between men and *** has been suggested to act as a modifier gene in genetic *** is a circulatory antimicrobial peptide synthesized by the *** plays a pivotal role in the regulation of iron *** has been shown to be regulated by iron,inflammation,oxidative stress,hypoxia,alcohol, hepatitis C and *** and genetic background have also been shown to modulate hepcidin expression in *** role of gender in the regulation of human hepcidin gene expression in the liver is ***,hepcidin may play a role in gender-based differences in iron metabolism and liver *** understanding of the mechanisms associated with gender-related differences in iron metabolism and chronic liver diseases may enable the development of new treatment strategies.

关键词： Alcohol Hepcidin Hepatitis C Hemochromatosis non-alcoholic steatohepatitis

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TLR4 signaling and the inhibition of liver hepcidin expression by alcohol

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World Journal of Gastroenterology 2014年第34期20卷 12161-12170页

作者： Emily Zmijewski Sizhao Lu duygu Dee Harrison-Findik Department of Internal Medicine University of Nebraska Medical CenterOmahaNE 68198-5820United States

AIM: To understand the role of toll-like receptor 4 (TLR4) signaling in the regulation of iron-regulatory hormone, hepcidin by chronic alcohol consumption.

关键词： Iron Small heterodimer partner protein nuclear factor-κB Alcoholic liver disease Inflammation

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The removal of Cr(Ⅵ) through polymeric supported liquid membrane by using calix[4]arene as a carrier

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Chinese Journal of Chemical Engineering 2019年第1期27卷 85-91页

作者： Canan Onac Ahmet Kaya duygu Ataman nefise Ayhan Gunduz H.Korkmaz Alpoguz Department of Chemistry Pamukkale University

In this work, the transport and removal of Cr(Ⅵ) were achieved through supported liquid membrane(SLM) by using a 5,17, di-tert-butyl-11,23-bis[(1,4-dioxa-8-azaspiro [4,5]decanyl)methyl]-25,26,27,28-tetrahydroxy calix[4]arene carrier, dissolved in 2-nitrophenyl octyl ether *** studied parameters are the solvent effect in the membrane phase, the effect of carrier concentration, and the acid type in the donor *** Celgard 2500 was used as a membrane *** used the Danesi mass transfer model to calculate the permeability coefficients for each studied *** addition, AFM and SEM techniques were used to characterize the surface morphology of the prepared Celgard 2500 membrane that included the calix[4]arene carrier.

关键词： Resorcinarene Liquid membrane Cr(Ⅵ) Surface characterization

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ROBOD, room-level occupancy and building operation dataset

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Building Simulation 2022年第12期15卷 2127-2137页

作者： Zeynep duygu Tekler Eikichi Ono Yuzhen Peng Sicheng Zhan Bertrand Lasternas Adrian Chong Department of the Built Environment National University of Singapore4 Architecture Drive117566Singapore

The availability of the building’s operation data and occupancy information has been crucial to support the evaluation of existing models and development of new data-driven *** paper describes a comprehensive dataset consisting of indoor environmental conditions,Wi-Fi connected devices,energy consumption of end uses(i.e.,HVAC,lighting,plug loads and fans),HVAC operations,and outdoor weather conditions collected through various heterogeneous sensors together with the ground truth occupant presence and count information for five rooms located in a university *** five rooms include two different-sized lecture rooms,an office space for administrative staff,an office space for researchers,and a library space accessible to all students.A total of 181 days of data was collected from all five rooms at a sampling resolution of 5 *** dataset can be used for benchmarking and supporting data-driven approaches in the field of occupancy prediction and occupant behaviour modelling,building simulation and control,energy forecasting and various building analytics.

关键词： building operation data occupancy data sensor fusion occupancy prediction building simulation and control

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Clinical assessment of demineralization and remineralization surrounding orthodontic brackets with FluoreCam

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Asian Pacific Journal of Tropical Biomedicine 2017年第4期7卷 373-377页

作者： Bora Korkut duygu Korkut Funda Yanikoglu Dilek Tagtekin Department of Restorative Dentistry Faculty of DentistryMarmara UniversityHealth Science Campus Department of Orthodontics Faculty of DentistryMarmara UniversityHealth Science Campus

Objective: To determine quantitatively the amount of demineralization and the ability of commercially available products and an experimental cream to inhibit or reverse orthodontic related ***: A total of 20 patients who were 25–35 years old and having orthodontic treatment for 6–8 months were *** risk assessments were done for each patient and ones with "moderate risk" were *** with fixed orthodontic appliances were divided into 4 groups(5 patients each) including one control and 3 study *** patients used same toothpaste 2 times a day during the 3 weeks study *** to the toothpaste first study group used MI Paste Plus(GC, Tokyo, Japan), second study group used Remin Pro(Voco, Cuxhaven, Germany) and third group used an experimental remineralizing cream per day for 3 *** central and lateral incisors of each patient were examined by FluoreCam(Daraza Therametric Technologies, USA) *** examinations were performed at baseline and at the end of 1st, 2nd and 3rd ***: According to the FluoreCam measurements the control group showed significant amount of demineralization at the end of 3 weeks, moreover the amount of demineralization has gradually increased in *** the end of the study all 3 study groups showed significant amount of remineralization and the amount of remineralization for all the 3 study groups has gradually increased in *** the amount of remineralization for 3rd study group was lesser than the 1st and 2nd study *** remineralization amounts for the 1st and 2 nd study groups were determined to be ***: This study demonstrated that demineralization is measurable around orthodontic brackets and the demineralization can be completely inhibited and/or reversed by the use of commercially available remineralization products.

关键词： Demineralization Remineralization FluoreCam Orthodontic brackets MI Paste Plus Remin Pro

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