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Journal of Pharmaceutical Analysis 2016年第6期6卷 404-409页

作者： Jing Ke Hanfei Dou Ximin Zhang dushimabararezi serge uhagaze Xiali Ding Yuming Dong Institute of Pharmaceutical Analysis School of PharmacyLanzhou University Key Laboratory of Gansu Province Chinese Medicine Preparation of Solid Dispersion Gansu longshenrongfa Pharmaceutical Industry Co.Ltd.

As a mono-sodium salt form of alendronic acid,alendronate sodium presents multi-level ionization for the dissociation of its four hydroxyl groups.The dissociation constants of alendronate sodium were determined in this work by studying the piecewise linear relationship between volume of titrant and p H value based on acidbase potentiometric titration reaction.The distribution curves of alendronate sodium were drawn according to the determined p Ka values.There were 4 dissociation constants(pKa_1=2.43,pKa_2=7.55,pKa_3=10.80,pKa_4=11.99,respectively) of alendronate sodium,and 12 existing forms,of which 4 could be ignored,existing in different p H environments.

关键词： Dissociation constants Alendronate sodium Distribution curve Piecewise linear regression Acid-base potentiometric titration

Taurine: a promising nutraceutic in the prevention of retinal degeneration

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Neural Regeneration Research 2024年第3期19卷 606-610页

作者： Diego García-Ayuso Johnny Di Pierdomenico Ana Martínez-Vacas Manuel Vidal-Sanz serge Picaud María PVillegas-Pérez Grupo de Investigación Oftalmología Experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaEspaña Sorbonne Université INSERMCNRSInstitut de la VisionParisFrance

Taurine is considered a non-essential amino acid because it is synthesized by most mammals.However,dietary intake of taurine may be necessary to achieve the physiological levels required for the development,maintenance,and function of certain tissues.Taurine may be especially important for the retina.The concentration of taurine in the retina is higher than that in any other tissue in the body and taurine deficiency causes retinal oxidative stress,apoptosis,and degeneration of photoreceptors and retinal ganglion cells.Low plasma taurine levels may also underlie retinal degeneration in humans and therefore,taurine administration could exert retinal neuroprotective effects.Taurine has antioxidant,anti-apoptotic,immunomodulatory,and calcium homeostasis-regulatory properties.This review summarizes the role of taurine in retinal health and disease,where it appears that taurine may be a promising nutraceutical.

关键词： amino acid anti-inflammatory antioxidant gamma-aminobutyric acid nutraceutical photoreceptor degeneration retina retinitis pigmentosa taurine

预测规则波浪中船舶运动和载荷的频域三维计算机程序

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哈尔滨工程大学学报（英文版） 2024年第1期23卷 64-73页

作者： Arash Abbasnia serge Sutulo C.Guedes Soares Centre for Marine Technology and Engineering(CENTEC) Instituto Superior TécnicoUniversidade de Lisboa1049-001 LisboaPortugal

The development of an in-house computer program for determining the motions and loads of advancing ships through sea waves in the frequency domain,is described in this paper.The code is based on the potential flow formulation and originates from a double-body code enhanced with the regular part of the velocity potential computed using the pulsing source Green function.The code is fully developed in C++language with extensive use of the object-oriented paradigm.The code is capable of estimating the excitation and inertial radiation loads or arbitrary incoming wave frequencies and incidence angles.The hydrodynamic responses such as hydrodynamic coefficients,ship motions,the vertical shear force and the vertical bending moment are estimated.A benchmark container ship and an LNG carrier are selected for testing and validating the computer code.The obtained results are compared with the available experimental data which demonstrate the acceptable compliance for the zero speed whereas there are some discrepancies over the range of frequencies for the advancing ship in different heading angles.

关键词： Frequency domain Advancing ships Diffraction theory Pulsing green’s function Boundary integral equation

Simulation and Performance Analysis of Six Types of Sun Tracker Approaches:A Comparative Analysis for Solar Concentrating Technology Application at Burkina Faso

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Journal of Energy and Power Engineering 2024年第1期18卷 1-8页

作者： Stanislas Sanfo serge Dimitri Bazyomo Tizane Daho Abdoulaye Ouedraogo Laboratoire de Physique et de Chimie de l’Environnement(LPCE) Departement de PhysiqueUnitéde Formation et de Recherche en Sciences Exactes et AppliquéesUniversitéJoseph KI-ZERBOOuagadougouBP 7021Burkina Faso Laboratory of Thermal and Renewable Energies Department of Physics Unit of Training and Research on Exact and Applied SciencesUniversity Joseph KI-ZERBOOuagadougouBP 7021Burkina Faso Laboratoire Recherche Développement(LARED) Universitéde OuahigouyaBurkina Faso

Modelization equations of six approaches for tracking the sun are recalled and used to evaluate the constraints and performances to which they lead to.The geographical study case is taken for the specific latitude of 12 North that is a good matching with the location of the country of Burkina Faso.Three decisive periods were locally established in order to consider the different travels of the sun on sky during one year.This work presents some technical data which facilitates the choice of sun tracking approaches with concern of a concentrator limits such as its angle of acceptance,its motion control card interpolation model,or its minimum irradiation level for energy conversion effectiveness.

关键词： Solar radiation sun tracker Burkina Faso experimental data

Seroprevalence of HBV and HCV among People Living with HIV in Burkina Faso and Diagnostic Performance of HIV/HCV/HBsAg Combined Rapid Test in Comparison with Architect Assays

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Open Journal of Medical Microbiology 2024年第1期14卷 1-10页

作者： serge Theophile Soubeiga Albert Theophane Yonli Alain Megabtche Nantchouang Jacques Simpore Department of Biomedical and Public Health Research Institute for Health Sciences (IRSS) Ouagadougou Burkina Faso Pietro Annigoni Biomolecular Research Centre (CERBA) Ouagadougou Burkina Faso Laboratory of Molecular Biology and Genetics (LABIOGENE) University Joseph Ki-Zerbo Ouagadougou Burkina Faso BIOMEX Laboratory Heidelberg Germany

Background: The diagnosis of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) remains a constraint for some populations in sub-Saharan Africa. This study aimed to determine the prevalence of HBV and HCV in people living with HIV and to evaluate the performance of a combined rapid test for the simultaneous detection of HIV, HBV, and HCV. Methods: This is a cross-sectional study that took place from February 2017 to November 2018 and included 139 HIV-infected individuals followed up at different medical centers in Ouagadougou, Burkina Faso. HBV and HCV serology tests were performed on-site using finger prick whole blood with HIV/HCV/HBsAg combined rapid test and then serum with two reference tests “Architect HBsAg Qualitative” and “Architect HIV Ag/Ab Combo”. Results: The mean age of the participants was 57 ± 8 years. Of the 139 participants, 10% (14/139) were HIV-1 positive, 71.9% (100/139) were HIV-2 positive, and 18.0% (25/139) were HIV-1/HIV-2 coinfected. The sensitivity and specificity of the HIV/HCV/HBsAg combined rapid test were 33.33% vs 99.11% and 20% vs 99.25% compared to Architect HBsAg Qualitative and Architect HIV Ag/Ab Combo, respectively. The Kappa and Youden Index values were 0.4262 and 0.3244 and 0.2707 and 0.1925, respectively, compared to each of the two reference tests. Conclusion: The results show that the HIV/HCV/HBsAg combined rapid test has poor diagnostic efficiency and should not be recommended for the diagnosis of these viruses.

关键词： HIV HBV HCV Prevalence Diagnosis Burkina Faso

Indirect Electroanalysis of 3-Methyl-4-Nitrophenol in Water Using Carbon Fiber Microelectrode Modified with Nickel Tetrasulfonated Phthalocyanine Complex

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Materials Sciences and Applications 2024年第2期15卷 25-35页

作者： Yibor Fabrice Roland Bako serge Foukmeniok Mbokou Boukaré Kaboré Issa Tapsoba Maxime Pontié Laboratoire de Chimie Analytique Environnementale et Bio-organique (LCAEBiO) Département de Chimie Université Joseph Ki-Zerbo Ouagadougou Burkina Faso Institut des Sciences et de Technologie Ecole Normale Supérieure Ouagadougou Burkina Faso Group of analysis and Processes Analysis (GA&P) Département de Chimie Université d’Angers Angers France Laboratoire de Sciences et Technologies (LaST) Université Thomas SANKARA Ouagadougou Burkina Faso

Electrochemical detection of 3-methyl-4-nitrophenol (MNP) in direct phenol oxidation occurs at high potentials and generally leads to progressive passivation of the electrochemical sensor. This study describes the use of a carbon fiber microelectrode modified with a tetrasulfonated nickel phthalocyanine complex for the detection of MNP at a lower potential than that of direct phenol oxidation. The MNP voltammogram showed the presence of an anodic peak at -0.11 V vs SCE, corresponding to the oxidation of the hydroxylamine group generated after the reduction of the nitro group. The effect of buffer pH on the peak current and SWV parameters such as frequency, scan increment, and pulse amplitude were studied and optimized to have better electrochemical response of the proposed sensor. With these optimal parameters, the calibration curve shows that the peak current varied linearly as a function of MNP concentration, leading to a limit of detection (LoD) of 1.1 μg/L. These results show an appreciable sensitivity of the sensor for detecting the MNP at relatively low potentials, making it possible to avoid passivation phenomena.

关键词： 3-Methyl-4-Nitrophenol Carbon Fiber Microelectrode Nickel Tetrasulfonated Phthalocyanine Indirect Electroanalysis Square Wave Voltammetry

Community Perception of Riparian Corridors Ecosystem Services and Implications for Environmental Education in Upper Oueme Catchment in Benin, West Africa

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Open Journal of Ecology 2024年第2期14卷 125-147页

作者： Socrate Mercator Dossou Kinnoumè serge Adomou Gérard Nounagnon Gouwakinnou Thierry Dèhouégnon Houéhanou Laboratory of Ecology Botany and Plant Biology Faculty of Agronomy University of Parakou Parakou Republic of Benin

The assessment of the local community perception of the value of riparian corridors is relevant to understand their attitude towards the conservation of such ecosystem. We conducted a semi-structured survey on the perception and importance attributed to the ecosystem services (ESs) provided by riparian corridors in 368 households across 70 villages located in a buffer zone of 5 km of servitude around the permanent rivers of the Upper Oueme watershed in Benin. We found that local communities easily reported provisioning and cultural ESs than regulating and supporting ones, indicating their misunderstanding of the main role of riparian corridor. Moreover, the supply of cropping areas was perceived as the most important ES. Educated respondents and high-income households had more knowledge of regulating ESs and supporting ESs, respectively. Overall, the highly perceived importance of the provision of cropping areas indicates a potential risk of agricultural encroachment of riparian corridors. We suggest the consideration of the current local perception of riparian corridor’s role in designing a sound environmental education aiming at the change of local population’s perception. This perception shift will promote a sustainable management of the riparian corridors.

关键词： Local Knowledge Direct Use Value Soil Formation Migration Importance Value Benin

Characterisation of Human-Wildlife Conflicts around the Kahuzi-Biega National Park, Eastern Democratic Republic of Congo

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Journal of Environmental Protection 2024年第3期15卷 343-356页

作者： Basubi Muke Matthieu Vwima Stany Ayagirwe Basengere Rodrigue Mushagalusa Freddy Benjamin-Fink Nicole Bobo Kadiri serge Faculty of Agricultural and Environmental Sciences Evangelical University in Africa Bukavu Congo Wildlife and Protected Areas Laboratory Forestry and Wood Technology Department of Forestry University of Dschang Dschang Cameroon Faculty of Economics and Management Sciences Evangelical University in Africa Bukavu Congo Conservation beyond Borders Organization Minnetonka USA

The history of mankind contains so many illustrations of well-classified and violent struggles against various animals over crop production in agricultural fields, attacks on human life or competition in order to have access to certain natural resources. The aim of this study is to characterise the human-wildlife conflicts that occur around the KBNP, especially with regard to primates. Surveys were carried out in 260 households selected using the snowball method. The results showed that human-wildlife conflicts around the KBNP are characterised by the destruction of crops in riparian fields by monkeys, chimpanzees and gorillas, the destruction of houses, physical attacks and zoonoses. Despite the conservation and protection measures for wildlife and local populations put in place by the Park’s managers, conflicts between local populations and the Park’s wild animals are still visible. These conflicts lead to the detention of wild animals by local people roaming in the villages and to poaching on the Park’s boundaries. The weakness of the community management policy on the part of the park managers and the resentment of the indigenous peoples towards the restriction of their access to natural resources are the major constraints on the sustainable management of conflicts between the local populations and the wild animals in the KBNP. The strategies for the sustainable resolution of human-wildlife conflicts around the KBNP must be geared towards and integrated into a community conservation approach.

关键词： Community Conservation Human-Wildlife Conflict Kahuzi-Biega National Park

Investigating the Impact of Base Heating and External Electric Field on PV Cell Performance under Intense Illumination

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Open Journal of Applied Sciences 2024年第5期14卷 1305-1314页

作者： Boubacar Soro Guy serge Tchouadep Esso-Ehanam Tchedre Kpeli Ousmane Souliga Adama Ouedraogo Issa Zerbo Martial Zoungrana Laboratory of Thermal and Renewable Energies Universit&#233 Joseph KI-ZERBO Ouagadougou Burkina Faso Institut des Sciences et Technologie Ecole Normale Sup&#233rieure Ouagadougou Burkina Faso

The characterization of the performances of a PV cell is linked to intrinsic factors of this cell. It is therefore important for us to identify the favorable or unfavorable conditions that affect the performance of PV cells. It is from this perspective that it seems judicious to us to study the simultaneous influence of the heating of the base and an external electric field on the performance of a PV cell under intense illumination of 50 suns. Two phenomena contribute to the heating of the base of a PV cell which is heating due to the transfer by conduction of solar radiation energy received by the surface of the PV cell and the heat generated inside the PV cell by various phenomena linked to the movement of photogenerated charged carriers. In this study, we take into account the heating linked to the movement of the charged carriers in the base. After a mathematical modeling of the PV cell considered, some hypotheses are formulated and the expressions of the electrical parameters are established as a function of the electric field and base temperature. Subsequently, we use numerical simulation to highlight the behavior of theses parameters as a function of temperature and of the intensity of the electric field. The results show that for any given temperature, the orientation of the electric field as considered in our work improves the performance of the PV cell while high temperatures degrade these performances. Furthermore, the analysis of the curves shows that the harmful effect of temperature on the performance of a PV cell is more accentuated at large values of electric field.

关键词： Collisions Thermalization Braking Electric Strength Base Temperature

Influence of Continental Atmospheric Forcing on the Decadal Variability of the West African Monsoon

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Atmospheric and Climate Sciences 2024年第1期14卷 1-28页

作者： Adjoua Moïse Landry Famien Sandrine Djakouré Bi Tra Jean Claude Youan serge Janicot Abé Delfin Ochou Arona Diedhiou Département des Sciences et Techniques Université Alassane Ouattara de Bouaké Bouaké C&#244te d’Ivoire LASMES-UFR SSMT Université Félix Houphou&#235t Boigny d’Abidjan Abidjan C&#244te d’Ivoire LSS-UFR SSMT Université Félix Houphou&#235t Boigny d’Abidjan Abidjan C&#244te d’Ivoire Laboratoire d’Océanographie et du Climat: Expérimentations et Approches Numériques Sorbonne Université IRD CNRS MNHN Paris France Université Grenoble Alpes IRD CNRS Grenoble INP IGE Grenoble France UFHB-IRD Joint International Laboratory of Research on NEXUS Climate Water Energy and Agriculture and Development of Cli-mate Services African Centre of Excellence CCBAD (Climate Change Biodiversity and Sustainable Agriculture) Université Félix Houphou&#235t-Boigny Abidjan C&#244te D’Ivoire

The West African Monsoon (WAM) is characterized by strong decadal and multi-decadal variability and the impacts can be catastrophic for the local populations. One of the factors put forward to explain this variability involves the role of atmospheric dynamics, linked in particular to the Saharan Heat Low (SHL). This article addresses this question by comparing the sets of preindustrial control and historical simulation data from climate models carried out in the framework of the CMIP5 project and observations data over the 20th century. Through multivariate statistical analyses, it was established that decadal modes of ocean variability and decadal variability of Saharan atmospheric dynamics significantly influence decadal variability of monsoon precipitation. These results also suggest the existence of external anthropogenic forcing, which is superimposed on the decadal natural variability inducing an intensification of the signal in the historical simulations compared to preindustrial control simulations. We have also shown that decadal rainfall variability in the Sahel, once the influence of oceanic modes has been eliminated, appears to be driven mainly by the activity of the Arabian Heat Low (AHL) in the central Sahel, and by the structure of the meridional temperature gradient over the inter-tropical Atlantic in the western Sahel.

关键词： Influence of Continental Atmospheric Forcing on the Decadal Variability of the West African Monsoon