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Energy Engineering 2022年第6期119卷 2585-2605页

作者： Bulbul Sharma N.Karthick durgesh prasad bagarty Lovely Professional University Jalandhar144402India College of Engineering and Technology Bhubaneswar751003India

This multilevel inverter methodology is the center of focus among researchers in recent *** has been focused due to its advantages over existing topologies,drawbacks and improvement of power quality,Multi-level inverter has the ability to generate nearly sinusoidal *** sinusoidal wave can be further improved by increasing the level of output voltage or with the help of filter design,and this manuscript presents single-phase Multi cell Multi-Level Inverter(MLI).It has been considered for reducing component count to get a higher number of output voltage levels and lower Total harmonics distortion *** comprises with four symmetric DC input voltage and 10 IGBT switches to produces stepped output of 9 level,and when deploy asymmetric Dc voltage source the same circuit will produce 31 level output with some changes in firing scheme,moreover this circuit is the family of cascaded hybrid bridge inverter so this circuit covered advantage of CHB MLI,This circuit uses lower *** switch as compared to existing conventional MLIs such as FC-MLI,CHB-MLI,NPC-MLI,This paper also provides one of most pertinent controls and modulation mechanisms for a MLI using a hybrid reference/carrier-oriented sinusoidal PWM *** last,simulated outcomes are to validate the performance of both architectures in MLI structure as well as verify the concept.

关键词： Conventional topology multi-level inverters(MLIs) pulse width modulations(PWM) reduced component counts total of harmonics distortion(THD)

Methyl-salicylate:A surveillance system fortriggering immunity in neighboring plants

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Journal of Integrative Plant Biology 2024年第2期66卷 163-165页

作者： Saumya Jaiswal durgesh Kumar Tripathi Ravi Gupta JingHe Zhong-Hua Chen Vijay Pratap Singh Plant Physiology Laboratory Department of Botany C.M.P.Degree CollegeA Constituent Post Graduate College ofUniversity of AllahabadPrayagraj 211002India Crop Nanobiology and Molecular Stress Physiology LabAmity Institute of Organic Agriculture Amity University UttarPradeshNoida 201313India College of General Education Kookmin UniversitySeoul 02707South Korea School of Science Western Sydney UniversitySydney 2751New South WalesAustralia Hawkesbury Institute for the Environment Western SydneyUniversitySydney 2751New South WalesAustralia

Plant behavioral actions have been one of the major topicsof research in plant biology and *** actionsfrom plants are determined by their instant structural andphysical reactions to the circumstances(Bouwmeester et al.,2019).Upon sensing abiotic factors such as salinity,flooding,high temperature,drought,plants make suitable changes intheir physiology and behavior to survive such harsh conditions.

关键词： immunity neighboring salinity

Changing trends in the minimally invasive surgery for corrosive esophagogastric stricture

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 799-811页

作者： Raja Kalayarasan Satish durgesh Surgical Gastroenterology JIPMERPuducherry 605006India

Esophagogastric stricture is the troublesome long-term complication of corrosive ingestion with a significant adverse impact on the quality of *** remains the mainstay of therapy in patients where endoscopic treatment is not feasible or fails to dilate the *** surgical management of esophageal stricture is open esophageal bypass using gastric or colon *** is the commonly used esophageal substitute,particularly in those with high pharyngoesophageal strictures and in patients with accompanying gastric *** colon bypass is performed using an open technique that requires a long midline incision from the xiphisternum to the suprapubic area,with adverse cosmetic outcomes and long-term complications like an incisional *** most of the affected patients are in the second or third decade of life minimally invasive approach is an attractive ***,minimally invasive surgery for corrosive esophagogastric stricture is slow to evolve due to the complex nature of the surgical *** advancements in laparoscopic skills and instrumentation,the feasibility and safety of minimally invasive surgery in corrosive esophagogastric stricture have been *** series have mainly used a laparoscopic-assisted approach,whereas more recent studies have shown the safety of a total laparoscopic *** changing trend from laparoscopic assisted procedure to a totally minimally invasive technique for corrosive esophagogastric stricture should be carefully disseminated to preclude adverse longterm ***,well-designed trials with long-term follow-ups are required to document the superiority of minimally invasive surgery for corrosive esophagogastric *** present review focuses on the challenges and changing trends in the minimally invasive treatment of corrosive esophagogastric stricture.

关键词： Robotics Laparoscopy Surgery Caustics Bypass Stricture

Mechanisms of NLRP3 inflammasome-mediated hepatic stellate cell activation: Therapeutic potential for liver fibrosis

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Genes & Diseases 2023年第2期10卷 480-494页

作者： Harsh Vardhan Charan durgesh Kumar Dwivedi Sabbir Khan Gopabandhu Jena Facility for Risk Assessment and Intervention Studies Department of Pharmacology and ToxicologyNational Institute of Pharmaceutical Education and ResearchSector-67S.A.S. NagarPunjab 160062India Department of Neuro-Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA

The liver injury leads to an inflammatory response, which causes the activation of hepatic stellate cells (HSCs) that further secrete ECM proteins and play an important role in liver fibrosis. Moreover, the inflammatory response is a driving force for fibrogenesis, which is triggered by many types of injuries. Exaggerated inflammatory immune responses are mediated by cytoplasmic protein complexes known as inflammasomes, which are involved in many chronic liver diseases. Inflammasomes are pattern recognition receptors (PRRs) that can sense any microbial motifs known as pathogen-associated molecular patterns (PAMPs), and host- or environmental-derived stress signals known as damage-associated molecular patterns (DAMPs). The inflammasomes cause caspase-mediated proteolytic cleavage of pro-IL-1β and pro-IL-18 into active IL-1β and IL-18. In this review, we provide a comprehensive summary of the important roles of NLRP3 inflammasome in the pathogenesis of liver fibrosis with an emphasis on several direct and indirect pathways responsible for the NLRP3 inflammasome-mediated HSCs activation and fibrogenesis. In addition, we discuss the general pharmacological and genetics strategies for the inhibition of NLRP3 inflammasome activation and its downstream signaling with examples of emerging pharmacotherapeutics, targeting the NLRP3 inflammasome signaling as well as a possible way to develop effective and safer NLRP3 inflammasome inhibitors.

关键词： Hepatic stellate cells Liver fibrosis NLRP3 activation NLRP3 inflammasome NLRP3 inhibitors

Autochthonous halotolerant plant growth-promoting rhizobacteria promote bacoside A yield of Bacopa monnieri(L.)Nash and phytoextraction of salt-affected soil

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Pedosphere 2020年第5期30卷 671-683页

作者： Umesh PANKAJ durgesh Narain SINGH Pooja MISHRA Pooja GAUR C.S.Vivek BABU Karuna SHANKER Rajesh Kumar VERMA Department of Soil Science CSIR-Central Institute of Medicinal and Aromatic PlantsLucknow 226015(India) Division of Biotechnology CSIR-Central Institute of Medicinal and Aromatic PlantsLucknow 226015(India) Division of Microbial Technology CSIR-Central Institute o f Medicinal and Aromatic PlantsLucknow 226015(India) Analytical Chemistry Department CSIR-Central Institute o f Medicinal and Aromatic PlantsLucknow 226015(India) Research Centre CSIR-Central Institute of Medicinal and Aromatic PlantsBangalore 560065(India)

Phytoremediation is a promising approach for reclamation of salt-affected *** is the most commonly used process,which exploits plants to absorb,immobilize,and accumulate salt in their *** this study,halotolerant plant growth-promoting rhizobacteria(PGPR)were isolated from the rhizosphere of wild grasses growing naturally in salt-affected areas of Lucknow,Uttar Pradesh(India)and were tested for their efficacies of salt-tolerance and plant growth-promoting(PGP)*** on 16S rRNA sequences,the most efficient halotolerant isolates possessing PGP traits were identified as Pseudomonas plecoglossicida(KM 233646),Acinetobacter calcoaceticus(KM 233647),Bacillus flexus(KM 233648),and Bacillus safensis(KM 233652).Application of these isolates as bio-inoculants significantly(P<0.05)increased the growth and bacoside A yield of a medicinal plant,Bacopa monnieri(L.)Nash,grown on natural salt-affected *** phytoremediation of salt-affected soil was evident by the substantial increase in shoot Na^+:K^+ratio of bio-inoculant-treated *** compared to un-inoculated control plants,the soil physico-chemical properties of bio-inoculant-treated plants were *** shoot and root biomass(fresh and dry weights),soil enzymes,and soil nutrient parameters showed significant positive correlations with the shoot Na+:K+***,the halotolerant PGPR screened in this study could be useful for the reclamation of saline soils concomitant with improved plant growth and bacoside A yield.

关键词： bio-inoculant phytoremediation plant productivity soil physico-chemical property soil salinity

Organo-Petrographic and Pore Facets of Permian Shale Beds of Jharia Basin with Implications to Shale Gas Reservoir

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Journal of Earth Science 2017年第5期28卷 897-916页

作者： Vinod Atmaram Mendhe Subhashree Mishra Ranjit G.Khangar Alka Damodhar Kamble durgesh Kumar Atul Kumar Varma H.Singh Sujeet Kumar Mollika Bannerjee CSIR-Central Institute of Mining and Fuel Research GSI-Geological Survey of India Central Region IIT (ISM)-Department of Chemical Engineering Indian Institute of Technology (ISM) IIT (ISM)-Department of Applied Geology Indian Institute of Technology (ISM)

The shale deposits of Damodar Valley have received great attention since preliminary studies indicate their potential for shale gas. However, fundamental information allied to shale gas re- servoir characteristics are still rare in India, as exploration is in the primary stage. In this study, Ba- rakar shale beds of eastern part of Jharia Basin are evaluated for gas reservoir characteristics. It is evident that Barakar shales are carbonaceous, silty, contains sub-angular flecks of quartz and mica, irregular hair-line fractures and showing lithological variations along the bedding planes, signifying terrestrial-fluviatile deposits under reducing environment. The values of TOC varies from 1.21 wt.% to 17.32 wt.%, indicating good source rock potentiality. The vitrinite, liptinite, inertinite and mineral matter ranging from 0.28 vol.% to 12.98 vol.%, 0.17 vol.% to 3.23 vol.%, 0.23 vol.% to 9.05 vol.%, and 74.74 vol.% to 99.10 vol.%, respectively. The ternary facies plot of maceral composition substan- tiated that Barakar shales are vitrinite rich and placed in the thermal-dry gas prone region. The low values of the surface area determined following different methods point towards low methane storage capacity, this is because of diagenesis and alterations of potash feldspar responsible for pore blocking effect. The pore size distribution signifying the micro to mesoporous nature, while Type II sorption curve with the H2 type of hysteresis pattern, specifies the heterogeneity in pore structure mainly combined-slit and bottle neck pores.

关键词： shale gas petrographic composition surface area pore disposition pore volume.

Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD^(2) score

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Stroke & Vascular Neurology 2021年第2期6卷 314-318页

作者： Shreyansh Shah Li Liang durgesh Bhandary Saga Johansson Eric E Smith Deepak L Bhatt Gregg C Fonarow Naeem D Khan Eric Peterson Janet Prvu Bettger Department of Neurology Duke University School of MedicineDurhamNorth CarolinaUSA Duke Clinical Research Institute DurhamNorth CarolinaUSA AstraZeneca UK Ltd CambridgeUK Hotchkiss Brain Institute and Department of Clinical Neurosciences University of CalgaryCalgaryAlbertaCanada Division of Cardiology Brigham and Women's HospitalBostonMassachusettsUSA Division of Cardiology Ronald Reagan UCLA Medical CenterLos AngelesCaliforniaUSA

Background Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack(TIA)and role of ABCD^(2) score in identifying high-risk individuals are not *** We identified 40825 Medicare beneficiaries hospitalised from 2011 to 2014 for a TIA to a Get With The Guidelines(GWTG)-Stroke hospital and classified them using ABCD^(2)s of mortality and rehospitalisation(all-cause,ischaemic stroke,haemorrhagic stroke,myocardial infarction,and gastrointestinal and intracranial haemorrhage)for high-risk versus low-risk groups adjusted for patient and hospital *** Of the 40825 patients,35118(86%)were high risk(ABCD^(2)≥4)and 5707(14%)were low risk(ABCD^(2)=0-3).Overall rate of mortality during 1-year follow-up after hospital discharge for the index TIA was 11.7%,44.3% were rehospitalised for any reason and 3.6%were readmitted due to *** with ABCD^(2) score≥4 had higher mortality at 1 year than not(adjusted HR 1.18,95%CI 1.07 to 1.30).Adjusted risks for ischaemic stroke,all-cause readmission and mortality/all-cause readmission at 1 year were also significantly higher for patients with ABCD^(2) score≥4 vs *** contrast,haemorrhagic stroke,myocardial infarction,gastrointestinal bleeding and intracranial haemorrhage risk were not significantly different by ABCD^(2) *** This study validates the use of ABCD^(2) score for long-term risk assessment after TIA in patients aged 65 years and *** efforts for community-based follow-up care after TIA are needed for ongoing prevention in Medicare beneficiaries who were hospitalised for TIA.

关键词： admitted score prevention

COLOR VIDEO CODING USING GENERALIZED SUBBAND DECOMPOSITION AND OPTIMIZED FILTER BANK

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COLOR VIDEO CODING USING GENERALIZED SUBBAND DECOMPOSITION A...

Acute dengue hypokalemic paralysis complicated by hypomagensemia

1996 3rd International Conference on Signal Processing(ICSP’96)

作者： durgesh Srivastava Sze Fong Yau Department of Electrical and Electronic Engineering The Hong Kong University of Science and Technology

＜正＞A general video codec is designed and implemented using generalized subband decomposition,vector quantization with variable bit allocation and motion *** resulting codec is capable of encoding color video in QCIF format at 15.2 kbits per second and ten frames per second. Simulation results are presented and compared with other video coding methods,such as the H.261 and MPEG standards.

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Journal of Acute Disease 2018年第6期7卷 262-264页

作者： durgesh Pushkar Bidyut Roy Hirdesh Chawla Tauhid Ahmad Department of Medicine King George Medical UniversityU.P.LucknowIndia

Endemic to over 100 countries dengue virus infection has now become the most rapidly spreading mosquito-borne disease in the world. Dengue symptoms range from minor flu-like symptoms to major complications like bleeding, shock, and rarely death due to organ failure. Atypical manifestations of neurological, cardiovascular, gastrointestinal origin are collectively grouped into the expanded dengue syndrome. Acute motor quadriparesis have been reported in several cases of dengue infection. We report a rare and non-fatal case of motor quadriparesis due to hypokalemia complicated by associated hypomagnesemia in a dengue positive patient.

关键词： Dengue Hypokalemia Hypomagnesemia Quadriparesis Acute

On Some Quality Issues of Component Selection in CBSD

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Journal of Software Engineering and Applications 2010年第6期3卷 556-560页

作者： Jeetendra Pande Raj Kishore Bisht durgesh Pant Vinay Kumar Pathak 不详

Component based development offers many potential benefits, viz. software reuse, reduced time-to-market, inter- operability, ease of quality certification etc. However, it is not always that benefits derived from addition of components from a component repository are more than the costs involved in developing the module from scratch. This work evaluates various software quality models and suggests recommendations for enhancing software quality in COTS (component off-the-shelf) based software products by designing software quality metrics that would help in managing and enhancing quality in component-based software development.

关键词： Component Based Software Development (CBSD) Components-off-the-Shelf (COTS) McCall’s Model Dormey’s Model Bohem’s Model