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effects of Microencapsulation of Nisin and Isolated Antimicrobial Peptides Using Water/oil/water emulsions on Preservation of Fresh Sichuan Pepper(Zanthoxylum Bungeanum)

Effects of Microencapsulation of Nisin and Isolated Antimicr...

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作者： dur e sameen 四川农业大学

学位级别：硕士

To improve the shelf life of food,research for the betterment of food packaging materials is ongoing,and biobased and natural polymers are getting increasing *** quality packaging not only improves the shelf life of food but also prevents food wastage and *** plastics are not biodegradable,they tend to harm the environment in many ways;the marine environment and landfills have become major *** 14%of plastics are recycled and only 5%are replaced,while the remaining are a threat to the ***,research is being focused on better alternatives of food packaging ***,biodegradable,biocompatible,and environmentally-friendly packaging materials are gaining much more *** can be produced from natural resources and waste material of natural food and *** the present study,edible microcapsules coating packaging,made from natural sources,were used to improve the shelf life of fresh Zanthoxylum bungeanum（Sichuan pepper,Huajiao）.LS-MS and HPLC of extracted proteins evaluated total 18 peptides in sample and 16 variant protein IDs were found with specific molecular *** average molecular weight（M_n）of extracted protein was 1.613×103 g/mol,weight-average molecular weight（M）was 4.047×103 g/mol,higher-average molecular weight（M）was1.423×103 g/mol,and its highest-peak molecular weight was（M）1.939×103 g/*** polydispersity index（M/M_n）was also evaluated to be *** DSC,the endothermic peak between the two major peaks（158°C）shows the denaturation of isolated protein *** FTIR spectrum indicates the distribution of its absorption peaks from 500-4000 cm.3100-3700 cmis attributed to the basic stretching mode of the-OH group,while 3311 cmis the O-H stretching vibration.2800-3000 cmcorresponds to the C-H tensile vibration of the triglyceride carbonyl *** the absorption peak at 2992 cmis related to the tensile shock of the C-H（CH2）group of few fatty acids in isolated *** efficienc

关键词： Microencapsulation edible coating Antimicrobial peptides Zanthoxylum bungeanum

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Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

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Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobato Mariam Masmudi-Martín Manuel F.López-Aranda Juan F.López-Téllez Gloria Delgado Pablo Granados-durán Celia Gaona-Romero Marta Carretero-Rey Sinforiano Posadas María e.Quiros-Ortega Zafar U.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de enfermedades Neurodegenerativas(CIBeRNeD) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of *** this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM *** findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dysfunction episodic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory loss regulator of G protein signaling

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Biomass gasification,catalytic technologies and energy integration for production of circular methanol:New horizons for industry decarbonisation

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Journal of environmental Sciences 2024年第6期140卷 306-318页

作者： Luis F.Bobadilla Lola Azancot Miriam González-Castañ estela Ruíz-López Laura Pastor-Pérez Francisco J.durán-Olivencia Runping Ye Katie Chong Paula HBlanco-Sánchez Zenthao Wu Tomás R.Reina JoséA.Odriozola Departamento de Química Inorgánica e Instituto de Ciencia de Materiales de Sevilla Centro Mixto CSIC-Universidad de SevillaAvda.Américo Vespucio 49Sevilla 41092Spain Departamento de Ingeniería Universidad Loyola AndalucíaAvda.de Las Universidades s/nSevilla 41704Spain Key Laboratory of Jiangxi Province for environment and energy Catalysis School of Chemistry and Chemical EngineeringNanchang UniversityNanchang330031China energy and Bioproducts Research Institute(eBRI) Aston UniversityBirminghamB47ETUnited Kingdom Department of Chemical and Process engineering University of SurreyGuildfordGU27XHUnited Kingdom

The Intergovernmental Panel on Climate Change(IPCC)recognises the pivotal role of renewable energies in the future energy system and the achievement of the zero-emission *** implementation of renewables should provide major opportunities and enable a more secure and decentralised energy supply *** fuels provide long-term solutions for the transport sector,particularly for applications where fuels with high energy density are *** addition,it helps reducing the carbon footprint of these sectors in the *** on biomass characteristics feedstock is essential for scaling-up gasification from the laboratory to *** review deals with the transformation biogenic residues into a valuable bioenergy carrier like biomethanol as the liquid sunshine based on the combination of modified mature technologies such as gasification with other innovative solutions such as membranes and microchannel *** abatement is a critical process in product gas upgrading since tars compromise downstream processes and equipment,for this,membrane technology for upgrading syngas quality is discussed in this *** reactor technology with the design of state-of-the-art multifunctional catalysts provides a path to develop decentralised biomethanol synthesis from biogenic ***,the development of a process chain for the production of(i)methanol as an intermediate energy carrier,(ii)electricity and(iii)heat for decentralised applications based on biomass feedstock flexible gasification,gas upgrading and methanol synthesis is analysed.

关键词： Biogenic residues Gasification Biomethanol Circular economy Microreactors

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An Algorithm to Reduce Compression Ratio in Multimedia Applications

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Computers, Materials & Continua 2023年第1期74卷 539-557页

作者： dur-e-Jabeen Tahmina Khan Rumaisa Iftikhar Ali Akbar Siddique Samiya Asghar Department of electronic engineering Sir Syed University of Engineering&TechnologyKarachiPakistan Department of Information&Computer Science Sir Syed University of Engineering&TechnologyKarachiPakistan

In recent years,it has been evident that internet is the most effective means of transmitting information in the form of documents,photographs,or videos around the *** purpose of an image compression method is to encode a picture with fewer bits while retaining the decompressed image’s visual *** transmission,this massive data necessitates a lot of channel *** order to overcome this problem,an effective visual compression approach is required to resize this large amount of *** work is based on lossy image compression and is offered for static color *** quantization procedure determines the compressed data quality *** images are converted from RGB to International Commission on Illumination CIe La^(∗)b^(∗);and YCbCr color spaces before being *** the transform domain,the color planes are encoded using the proposed quantization *** improve the efficiency and quality of the compressed image,the standard quantization matrix is updated with the respective image *** used seven discrete orthogonal transforms,including five variations of the Complex Hadamard Transform,Discrete Fourier Transform and Discrete Cosine Transform,as well as thresholding,quantization,de-quantization and inverse discrete orthogonal transforms with CIe La^(∗)b^(∗);and YCbCr to RGB *** to signal noise ratio,signal to noise ratio,picture similarity index and compression ratio are all used to assess the quality of compressed *** the relevant transforms,the image size and bits per pixel are also *** the(n,n)block of transform,adaptive scanning is used to acquire the best feasible compression *** of these characteristics,multimedia systems and services have a wide range of possible applications.

关键词： Color image compression color spaces discrete orthogonal transforms(DOTs) peak-to-signal noise ratio(PSNR) similarity index

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Improving Routine Immunization Coverage Through Optimally Designed Predictive Models

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Computers, Materials & Continua 2022年第1期70卷 375-395页

作者： Fareeha sameen Abdul Momin Kazi Majida Kazmi Munir A Abbasi Saad Ahmed Qazi Lampros K Stergioulas Faculty of electrical and Computer engineering NED University of Engineering and TechnologyKarachi75270Pakistan Department of Pediatrics and Child Health Aga Khan UniversityKarachi74800Pakistan Surrey Business School University of SurreyGuildfordGU27XHUnited Kingdom Neurocomputation Lab National Centre of Artificial IntelligenceNED University of Engineering&TechnologyKarachi75270Pakistan Faculty of IT and Design The Hague University of Applied Sciences2521 ENThe HagueThe Netherlands

Routine immunization(RI)of children is the most effective and timely public health intervention for decreasing child mortality rates around the *** being a low-and-middle-income-country(LMIC)has one of the highest child mortality rates in the world occurring mainly due to vaccine-preventable diseases(VPDs).For improving RI coverage,a critical need is to establish potential RI defaulters at an early stage,so that appropriate interventions can be targeted towards such populationwho are identified to be at risk of missing on their scheduled vaccine *** this paper,a machine learning(ML)based predictivemodel has been proposed to predict defaulting and non-defaulting children on upcoming immunization visits and examine the effect of its underlying contributing *** predictivemodel uses data obtained from Paigham-e-Sehat study having immunization records of 3,113 *** design of predictive model is based on obtaining optimal results across accuracy,specificity,and sensitivity,to ensure model outcomes remain practically relevant to the problem *** optimization of predictive model is obtained through selection of significant features and removing data *** machine learning algorithms were applied for prediction of defaulting children for the next immunization *** results showed that the random forest model achieves the optimal accuracy of 81.9%with 83.6%sensitivity and 80.3%*** main determinants of vaccination coverage were found to be vaccine coverage at birth,parental education,and socioeconomic conditions of the defaulting *** information can assist relevant policy makers to take proactive and effective measures for developing evidence based targeted and timely interventions for defaulting children.

关键词： Machine learning predictive models routine immunization vaccine coverage pakistan optimization SMOTe

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Design of multilayer hybrid sol-gel coatings with bifunctional barrier-bioactive response on the elektron 21 magnesium alloy for biomedical applications

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Journal of Magnesium and Alloys 2021年第6期9卷 2097-2112页

作者： K.S.durán N.Hernández L.M.Rueda C.A.Hernández-Barrios A.e.Coy F.Viejo Grupo de Investigación en Desarrollo y Tecnología de Nuevos Materiales(GIMAT) Universidad Industrial de Santander9 Cra.27Colombia Grupo de Investigación de las Ciencias de las Ingenierías(GICI) Universidad de San BuenaventuraCartagenaCalle Real de TerneraDiagonal 32#30-966Colombia

The present study aims to develop multilayer barrier-bioactive hybrid sol-gel coatings from a mixture of the silane precursors tetraethylorthosilicate(TeOS)and glycidoxypropyltriethoxysilane(GPTMS)deposited on the elektron 21 magnesium *** purpose of the inner layer(barrier coating)was to provide corrosion protection to the magnesium alloy,whereas the outer layer(bioactive coating)was doped with different Ca and Mg contents to produce a bioactive *** coatings were characterised using scanning electron microscopy(SeM)and their corrosion behaviour was evaluated by anodic polarisation and electrochemical impedance spectroscopy after immersion in simulated body fluid(SBF)at 37±0.5°*** experimental results showed that the multilayer coatings increased the corrosion resistance of the alloy up to three orders of magnitude during immersion in SBF *** the other hand,the presence of Ca and Mg in the bioactive coating promoted the growth of apatite-like ***,an increment of salt content favoured the formation of porous coatings,which allowed the access of the electrolyte to the substrate leading to their rapid *** the latter,this research endorses the premise that the TeOS-GPTMS hybrid system represents a promising alternative to produce bifunctional barrier-bioactive coatings.

关键词： Magnesium bioactivity coating sol-gel eIS corrosion

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Deep Reinforcement Learning Based Unmanned Aerial Vehicle (UAV) Control Using 3D Hand Gestures

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Computers, Materials & Continua 2022年第9期72卷 5741-5759页

作者： Fawad Salam Khan Mohd Norzali Haji Mohd Saiful Azrin B.M.Zulkifli Ghulam e Mustafa Abro Suhail Kazi dur Muhammad Soomro Faculty of electrical and electronics(FKee) Universiti Tun Hussein Onn MalaysiaParit Raja81756Malaysia Department of electrical&electronic engineering Universiti Teknologi PETRONASSeri Iskandar32610Malaysia Faculty of engineering Science and Technology Isra UniversityHyderabad71000Pakistan Department of Innovation CONVSYS(Pvt)Ltd.44000IslamabadPakistan

The evident change in the design of the autopilot system produced massive help for the aviation industry and it required frequent *** learning delivers appropriate outcomes when considering a continuous environment where the controlling Unmanned Aerial Vehicle(UAV)required maximum *** this paper,we designed a hybrid framework,which is based on Reinforcement Learning and Deep Learning where the traditional electronic flight controller is replaced by using 3D hand *** algorithm is designed to take the input from 3D hand gestures and integrate with the Deep Deterministic Policy Gradient(DDPG)to receive the best reward and take actions according to 3D hand gestures *** UAV consist of a Jetson Nano embedded testbed,Global Positioning System(GPS)sensor module,and Intel depth *** collision avoidance system based on the polar mask segmentation technique detects the obstacles and decides the best path according to the designed reward *** analysis of the results has been observed providing best accuracy and computational time using novel design framework when compared with traditional Proportional Integral Derivatives(PID)flight *** are six reward functions estimated for 2500,5000,7500,and 10000 episodes of training,which have been normalized between 0 to−*** best observation has been captured on 2500 episodes where the rewards are calculated for maximum *** achieved training accuracy of polar mask segmentation for collision avoidance is 86.36%.

关键词： Deep reinforcement learning UAV 3D hand gestures obstacle detection polar mask

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Systematic study of the dependence of magnetic and structural properties of Nd2Fe14B powders on the average particle size

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Journal of Rare earths 2020年第9期38卷 961-968,I0002页

作者： J.F.durán Perdomo G.A.Pérez Alcázar H.D.Colorado J.A.Tabares L.e.Zamora J.J.S.Garitaonandia Department of Physics University of ValleA.A.25360 CaliColombia Applied Physics II Department Basque Country University48080 BilbaoSpain

A systematic study of the magnetic and structural properties dependence on the particle size was *** this,commercial NdFeB powder was separated into five different mean particle sizes using ***,from the original powder,eleven samples were also produced by mechanical milling assisted by surfactant,using various milling times.A total of sixteen samples were studied by scanning electron microscopy(SeM),X-ray diffraction(XRD),vibrating sample magnetometry(VSM),and Mdssbauer spectrometry(MS).The particle sizes of the samples vary from the micrometer to the nanometer *** crystallite size decreases with decreasing particle *** result indicates that the Nd2Fe14B phase is found in all the samples,and the presence of this phase is also corroborated by MS using six sextets for fitting their spectra,with an additional singlet corresponding to the Nd1.1Fe4B4 *** mean hyperfine magnetic field increases with increasing particle size because the magnetic dipolar interaction between the magnetic moment of the particles increases with particle *** the VSM measurements the magnetic energy density(BH)max values were calculated for different particle sizes,and their maximum value of 34.45 MGOe is obtained for the sample with the particle size of 60μm.

关键词： Hard magnetic material XRD Mossbauer spectrometry Magnetization Particle size Rare earths

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Neuropsychological features of progranulin-associated frontotemporal dementia: a nested case-control study

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Neural Regeneration Research 2021年第5期16卷 910-915页

作者： Marisa Lima Miguel Tábuas-Pereira Diana duro João durães Daniela Vieira Inês Baldeiras Maria Rosário Almeida Isabel Santana Neurology Department Centro Hospitalar e Universitário de CoimbraCoimbraPortugal University of Coimbra Faculty of MedicineCoimbraPortugal University of Coimbra Center for Neuroscience and Cell BiologyCoimbraPortugal University of Coimbra Center for Research in Neuropsychology and Cognitive Behavioral Intervention(CINEICC)Faculty of Psychology and Educational SciencesCoimbraPortugal

The distinction between sporadic and genetic behavioural-variant frontotemporal dementia(bvFTD)regarding some neuropsychological(NP)features remains ***,progranulin(GRN)-associated bvFTD frequently presents with early episodic memory impairment and some degree of parietal dysfunction which are supporters of Alzheimer’s disease(AD)*** this context,we aimed to characterize the NP profile of GRN-bvFTD as compared to sporadic-bvFTD and AD in patients with mild dementia(Mini-Mental State examination score≥17 and Clinical Dementia Rating Scale score≤*** identified 21 patients at Centro Hospitalar e Universitário de Coimbra,Portugal with GRN mutations belonging to fifteen different *** our focus was bvFTD variants,FTD-related aphasic forms(3 patients)were *** remaining 18 GRN-bvFTD were further matched with 18 sporadic-bvFTD and 18 AD patients according to disease staging,age and *** patients completed the Mini-Mental State examination,Montreal Cognitive Assessment(MoCA)and a comprehensive NP assessment *** were converted into *** between groups in individual NP measures and NP domains were assessed through non-parametric tests(Kruskal-Wallis test analysis)and eta squared(ŋ2)was calculated as a measure of effect *** comparisons show that GRN patients have worse performances on verbal retrieval processes(P=0.039,ŋ2=0.110)and visuoconstructive abilities(P=0.039,ŋ2=0.190)than sporadic bvFTD *** compared to AD,GRN patients present a higher impairment in frontal(P=0.001,ŋ2=0.211)and parietal(P=0.041,ŋ2=0.129)measures and a better performance in memory tasks(P=0.020,ŋ2=0.120).Sporadic-bvFTD forms are worse than AD in frontal measures(P=0.032,ŋ2=0.200),being better in both memory(P=0.010,ŋ2=0.131)and visuospatial skills(P=0.023,ŋ2=0.231).Considering these results,we conclude that GRN-bvFTD patients present a NP profile that associates the typical patterns of FTD and AD ***

关键词： Alzheimer’s disease behavioral variant frontotemporal dementia cognitive profile frontotemporal dementia genetics memory neuropsychology progranulin visuoconstructive ability

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estimating the basic reproductive ratio for the ebola outbreak in Liberia and Sierra Leone

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Infectious Diseases of Poverty 2015年第1期4卷 114-121页

作者： Adnan Khan Mahim Naveed Muhammad dur-e-Ahmad Mudassar Imran Department of Mathematics Lahore University of Management SciencesLahorePakistan Department of Mathematics State University of New York at PlattsburghPlattsburghNYUSA Department of Mathematics Waterloo UniversityWaterlooONCanada Department of Mathematics and Natural Sciences GULF University for Science and TechnologyMubarak Al-AbdullahWest MishrefKuwait

Background:ebola virus disease has reemerged as a major public health crisis in Africa,with isolated cases also observed globally,during the current ***:To estimate the basic reproductive ratio R0,which is a measure of the severity of the outbreak,we developed a SeIR(susceptible-exposed-infected-recovered)type deterministic model,and used data from the Centers for Disease Control and Prevention(CDC),for the ebola outbreak in Liberia and Sierra *** different data sets are available:one with raw reported data and one with corrected data(as the CDC suspects under-reporting).Results:Using a deterministic ordinary differential equation transmission model for ebola epidemic,the basic reproductive ratio R0 for Liberia resulted to be 1.757 and 1.9 for corrected and uncorrected case data,*** Sierra Leone,R0 resulted to be 1.492 and 1.362 for corrected and uncorrected case data,*** each of the two cases we considered,the estimate for the basic reproductive ratio was initially greater than unity leading to an epidemic ***:We obtained robust estimates for the value of R0 associated with the 2014 ebola outbreak,and showed that there is close agreement between our estimates of *** of our model also showed that effective isolation is required,with the contact rate in isolation less than one quarter of that for the infected non-isolated population,and that the fraction of high-risk individuals must be brought to less than 10%of the overall susceptible population,in order to bring the value of R0 to less than 1,and hence control the outbreak.

关键词： epidemiology ebola virus disease Transmission model Basic reproductive ratio

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