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Utilization and Satisfaction with HIV Services at 7 Provinces in Vietnam: A Cross-Sectional Study

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World Journal of AIDS 2022年第2期12卷 65-82页

作者： Le Bao Chau Pham Thi Huyen Chang duong minh duc Hoang Van minh Luu Quoc Toan Bui Thi Tu Quyen Le Thi Vui Bui Thi Thu Ha Hanoi University of Public Health Hanoi Vietnam

The study was carried out to determine utilization and satisfaction with essential HIV services from HIV individuals and high-risk populations in 7 socioeconomic provinces nationwide. A cross-sectional approach was applied in the study. Data were collected through face-to-face interviews using self-report questionnaires. Findings from 2380 respondents indicated a high percentage of utilization as well as a high level of satisfaction, in particular among men who have sex with men (MSM) and female sex worker (FSW) sub-group. Needle, syringe, and condom programs had lower usage and satisfaction mean scores in comparison with other services. The proportion of people who used drugs (PWID) and participated in the needle and syringe program was 53.6%. HIV counseling and testing uptake proportion of overall respondents in the last 12 months was 82.2% while the rate of antiretroviral treatment among infected PWID was 74.9%. The level of satisfaction with treatment services was found to be higher than preventive interventions (p ducational attainment, and marital status with subjects’ satisfaction with several HIV services. Preventive services, especially needle, syringe and condom programs should be prioritized to scale up the coverage and effectiveness. Innovative approaches targeting at PWID should be promoted to increase their access to prevention programs as well as HIV care when needed.

关键词： HIV Service Utilization Satisfaction

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

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Journal of Pharmaceutical Analysis 2024年第1期14卷 16-38页

作者： Nguyen Quang Thu Nguyen Tran Nam Tien Nguyen Thi Hai Yen Thuc-Huy duong Nguyen Phuoc Long Huy Truong Nguyen Department of Pharmacology and PharmacoGenomics Research Center Inje University College of MedicineBusan47392Republic of Korea Department of Chemistry University of EducationHo Chi Minh City700000Viet Nam Faculty of Pharmacy Ton Duc Thang UniversityHo Chi Minh City700000Viet Nam

The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB *** strategies to facilitate drug combinations,including pharmacokinetics-guided dose optimization and toxicology studies of first-and second-line anti-TB drugs have also been introduced and *** chromatography-mass spectrometry(LC-MS)has arguably become the gold standard in the analysis of both endo-and exo-genous *** technique has been applied successfully not only for therapeutic drug monitoring(TDM)but also for pharmacometabolomics *** improves the effectiveness of treatment,reduces adverse drug reactions,and the likelihood of drug resistance development in TB patients by determining dosage regimens that produce concentrations within the therapeutic target *** on TDM,the dose would be optimized individually to achieve favorable *** is essential in generating and validating hypotheses regarding the metabolism of anti-TB drugs,aiding in the discovery of potential biomarkers for TB diagnostics,treatment monitoring,and outcome *** article highlighted the current progresses in TDM of anti-TB drugs based on LC-MS bioassay in the last two ***,we discussed the advantages and disadvantages of this technique in practical *** pressing need for non-invasive sampling approaches and stability studies of anti-TB drugs was ***,we provided perspectives on the prospects of combining LC-MS-based TDM and pharmacometabolomics with other advanced strategies(pharmacometrics,drug and vaccine developments,machine learning/artificial intelligence,among others)to encapsulate in an all-inclusive approach to improve treatment outcomes of TB patients.

关键词： Tuberculosis Therapeutic drug monitoring LC-MS MIPD Pharmacometabolomics Precision medicine

An isogeometric approach to free vibration analysis of bi-directional functionally graded porous doubly-curved shallow microshells with variable length-scale parameters

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Frontiers of Structural and Civil Engineering 2023年第12期17卷 1871-1894页

作者： Khuat duc duong Dao Nhu MAI Phung Van minh Tran Van KE Faculty of Mechanical Engineering Hanoi University of IndustryHanoi 100000Vietnam Institute of Mechanics Vietnam Academy of Science and TechnologyHanoi 100000Vietnam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoi 100000Vietnam

This study uses iso-geometric investigation,which is based on the non-uniform rational B-splines(NURBS)basis function,to investigate natural oscillation of bi-directional functionally graded porous(BFGP)doublycurved shallow microshells placed on Pasternak foundations with any boundary *** characteristics of the present material vary in both thickness and axial directions along the *** be more specific,a material length-scale coefficient of the microshell varies in both thickness and length directions as the material's mechanical *** is able to develop a differential equation system with varying coefficients that regulate the motion of BFGP double-curved shallow microshells by using Hamilton principle,Kirchhoff-Love hypothesis,and modified couple stress *** numerical findings are reported for thin microshells that are spherical,cylindrical,and hyperbolic paraboloidal,with a variety of planforms,including rectangles and *** validity and effectiveness of the established model are shown by comparing the numerical results given by the proposed formulations with previously published findings in many specific *** addition,influences of length scale parameters,power-law indexes,thickness-to-side ratio,and radius ratio on natural oscillation responses of BFGP microshells are investigated in detail.

关键词： Kirchhoff-Love's shell theory isogeometric analysis bi-directional functionally graded free vibration variable length-scale parameter

Profiling of Urban Noise Using Artificial Intelligence

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Computer Systems Science & Engineering 2023年第5期45卷 1309-1321页

作者： Le Quang Thao duong duc Cuong Tran Thi Tuong Anh Tran duc Luong Ph.D.Faculty of Physics VNU University of ScienceHanoi100000Vietnam University of Science Vietnam National UniversityHanoi100000Vietnam The International School of Penang(Uplands) PenangMalaysia Alpha School Hanoi100000Vietnam

Noise pollution tends to receive less awareness compared to other types of pollution,however,it greatly impacts the quality of life for humans such as causing sleep disruption,stress or hearing *** urban sound through the identification of noise sources in cities could help to benefit livability by reducing exposure to noise pollution through methods such as noise control,planning of the soundscape environment,or selection of safe living *** this paper,we proposed a self-attention long short-term memory(LSTM)method that can improve sound classification compared to previous *** attention mechanism will be designed solely to capture the key section of an audio data *** is practical as we only need to process important parts of the data and can ignore the rest,making it applicable when gathering information with long-term *** dataset used is the Urbansound8k dataset which specifically pertains to urban environments and data augmentation was applied to overcome imbalanced data and dataset *** audio sources in the dataset were normalized to mono *** the dataset above,an experiment was conducted to confirm the suitability of the proposed model when applied to the mel-spectrogram and MFCC(Mel-Frequency Cepstral Coefficients)datasets transformed from the original *** the classification accuracy depends on the machine learning models as well as the input data,therefore we have evaluated different class models and extraction methods to find the best *** combining data augmentation techniques and various extraction methods,our classification model has achieved state-of-the-art performance,each class accuracy is up to 98%.

关键词： Urban noise noise classification mel-spectrogram MFCC LSTM self-attention

Tail dependence in emerging ASEAN-6 equity markets: empirical evidence from quantitative approaches

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Financial Innovation 2020年第1期6卷 69-94页

作者： Duy duong Toan Luu duc Huynh University of Economics Ho Chi Minh CityVietnam School of Banking University of Economics Ho Chi Minh City59C Nguyen Dinh Chieu StreetDistrict 3Ho Chi Minh CityVietnam

This study contributes a rich set of quantitative methodologies including a nonparametric approach(Chi-plots and K-plots)as well as copulas(traditional and timevarying with Student’s t-copulas)to the existing literature in terms of determining the dependence structure in ASEAN stock *** on the emerging ASEAN equity returns of six countries from January 2001 to December 2017,we found that Student’s t-copulas under time-varying approach is the most appropriate approach to explain these *** all research return pairs,the dependence between Vietnam and other ASEAN equity indices has the lowest ***,all couples show left-and right-tail dependence by each pair for pre-and postfinancial ***,diversification across these pairs of equity markets from ASEAN is still adequate for international investors,though it might trigger contagion risks.

关键词： ASEAN Stock indexes Chi-plots K-plots T-copulas Time-varying copulas

Protective effect of Tetracera scandens *** extract against CCl_4-induced acute liver injury in rats

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Asian Pacific Journal of Tropical Biomedicine 2015年第3期5卷 221-227页

作者： Tung Bui Thanh Hai Nguyen Thanh Hue Pham Thi minh Huong Le-Thi-Thu Huong duong Thi Ly Loi Vu duc School of Medicine and Pharmacy Vietnam National University Hanoi University of Pharmacy

Objective:To investigate the protective potential of ethanolic extracts of Tetracera scandens L.(***) against CCl_4 induced oxidative stress in liver ***:Dried leaf powder of *** was extracted with ethanol and concentrated to yield a dry *** were administered with 100 mg/kg of ethanolic extracts orally once daily for one *** were subsequently administered with a single dose of CCl_4(I mL/kg body weight,intraperitoneal injection).Various assays,such as serum levels of alanine aminotransferase,aspartate aminotransferase,lipid peroxidation,protein oxidation(carbonyl protein group),tumor necrosis factor alpha,catalase,superoxide dismutase,and glutathione peroxidase,were used to assess damage caused by CCl_4 and the protective effects of the ethanol extract on liver ***:Hepatotoxicity induced by CCl_4 was evidenced by a significant increase in serum aspartate aminotransferase and alanine aminotransferase level,lipid peroxidation,protein carbonyl group,and tumor necrosis factor alpha,as well as decreased activity of the hepatic antioxidant enzymes(*** *** glutathione peroxidase).Treatment with ethanolic *** extracts prevented all of these typically observed changes in CCl_4-treated ***:Our findings indicate that *** has a significant protective effect against CCl_4 induced hepatotoxicity in *** may be due to its antioxidant properties.

关键词： Tetracera scandens L Antioxidant Carbon tetrachloride Liver toxicity Lipid peroxidation

Novel hybrid models of ANFIS and metaheuristic optimizations (SCE and ABC) for prediction of compressive strength of concrete using rebound hammer field test

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Frontiers of Structural and Civil Engineering 2022年第8期16卷 1003-1016页

作者： Dung Quang VU Fazal EJALAL Mudassir IQBAL Dam duc NGUYEN duong Kien TRONG Indra PRAKASH Binh Thai PHAM University of Transport Technology Hanoi 100000Vietnam Department of Civil Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Civil Engineering University of Engineering and TechnologyPeshawar 25120Pakistan DDG(R)Geological Survey of India Gandhinagar 382010India

In this study,we developed novel hybrid models namely Adaptive Neuro Fuzzy Inference System(ANFIS)optimized by Shuffled Complex Evolution(SCE)on the one hand and ANFIS with Artificial Bee Colony(ABC)on the other *** were used to predict compressive strength(Cs)of concrete relating to thirteen concrete-strength affecting parameters which are easy to determine in the *** and laboratory tests data of 108 structural elements of 18 concrete bridges of the Ha Long-Van Don Expressway,Vietnam were *** dataset was randomly divided into a 70:30 ratio,for training(70%)and testing(30%)of the hybrid *** of the developed fuzzy metaheuristic models was evaluated using standard statistical metrics:Correlation Coefficient(R),Root Mean Square Error(RMSE)and Mean Absolute Error(MAE).The results showed that both of the novel models depict close agreement between experimental and predicted ***,the ANFIS-ABC model reflected better convergence of the results and better performance compared to that of ANFIS-SCE in the prediction of the concrete ***,the ANFIS-ABC model can be used for the quick and accurate estimation of compressive strength of concrete based on easily determined parameters for the design of civil engineering structures including bridges.

关键词： shuffled complex evolution artificial bee colony ANFIS concrete compressive strength Vietnam

A novel approach for synthesis of hierarchical mesoporous Nd2O3 nanomaterials

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Journal of Rare Earths 2017年第7期35卷 677-682页

作者： Le Huu Trinh Dinh Quang Khieu Hoang Thai Long Tran Thai Hoa duong Tuan Quang Nguyen duc Cuong College of Sciences Hue University 77 Nguyen Hue Hue City Viet Nam Faculty of Hospitality and Tourism Hue University 22 Lam Hoang Hue CityViet Nam College of Education Hue University 34 Le LoL Hue City Viet Nam

A novel route to the fabrication of hierarchical mesoporous Nd_2O_3 nanostructures including nanospheres and nanoporous network was described. Their structure and morphology evolution of the as-synthesized materials were determined by various techniques such as scanning electron microscopy, transmission electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, energy-dispersive X-ray spectroscopy, Fourier transforminfrared spectra, nitrogen adsorption/desorption isotherm, and a formation mechanism was proposed. The results revealed that the Nd_2O_3 nanospheres had the diameter of 300 nm, which were composed of small primary nanoparticles（NPs） with the size of 10 nm. The nanoporous structure also formed the NPs of ca. 10 nm which were connected with each other to form a three-dimensional（3D） texture. This simple and mild approach to fabricate hierarchical mesoporous Nd_2O_3 nanostructures could be easily scaled up and potentially extended to synthesize other oxide hierarchical structures.

关键词： Nd2O3 hierarchical nanostructures nanospheres nanoporous network rare earths

Plasmonic Ag‑Decorated Few‑Layer MoS2 Nanosheets Vertically Grown on Graphene for Efficient Photoelectrochemical Water Splitting

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Nano-Micro Letters 2020年第12期12卷 159-172页

作者： Dong‑Bum Seo Tran Nam Trung Dong‑Ok Kim duong Viet duc Sungmin Hong Youngku Sohn Jong‑Ryul Jeong Eui‑Tae Kim Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Department of Chemistry Chungnam National UniversityDaejeon 34134Republic of Korea

A controllable approach that combines surface plasmon resonance and twodimensional(2D)graphene/MoS2 heterojunction has not been implemented despite its potential for efficient photoelectrochemical(PEC)water *** this study,plasmonic Ag-decorated 2D MoS2 nanosheets were vertically grown on graphene substrates in a practical large-scale manner through metalorganic chemical vapor deposition of MoS2 and thermal evaporation of *** plasmonic Ag-decorated MoS2 nanosheets on graphene yielded up to 10 times higher photo-to-dark current ratio than MoS2 nanosheets on indium tin *** significantly enhanced PEC activity could be attributed to the synergetic effects of SPR and favorable graphene/2D MoS2 *** Ag nanoparticles not only increased visible-light and near-infrared absorption of 2D MoS2,but also induced highly amplified local electric field intensity in 2D *** addition,the vertically aligned 2D MoS2 on graphene acted as a desirable heterostructure for efficient separation and transportation of photo-generated *** study provides a promising path for exploiting the full potential of 2D MoS2 for practical large-scale and efficient PEC water-splitting applications.

关键词： Photoelectrocatalysis Molybdenum disulfide Graphene Surface plasmon resonance