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THE REpAIR OF SpINAL CORD INJURY——A LONG WAY AHEAD

神经解剖学杂志 2005年第2期21卷 212-221页

作者：王廷华李咏梅 dubus p Merlio Jp Institute of Neuroscience Kunming Medical College Kunming 650031 Lab of Molecular pathology E. A 2406 Universite Victor Segalen Bordeaux 2 33076 Bordeaux France

Damage to spinal cord (SC) often produces long-lasting functional deficits involving sensory and movement. After injuries, SC may perform a series of changes, which injured neurons may suffer death, persistent atrophy or recovery, while damaged axons initially show a growth response, but later their regeneration is aborted as a dense permanent scar is laid down within the core of the wound. Clinically, functional recovery from such injuries is poor and morbidity is severe. Consequently, the prevalence of patients permanently disabled from spinal cord injury (SCI) is high, estimated at more than 1∶1000 of the population of North America (Office of Technology Assessment USA, 1990) [1] .

关键词：脊髓损伤修复技术生长因子生长抑制因子一氧化氮合酶神经生长因子

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甲型流感季节性暴发的儿科特点及其在儿科急诊室和儿科病房的费用负担

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世界核心医学期刊文摘（儿科学分册） 2006年第5期2卷 19-20页

作者： Blanc p. No■l G. dubus J.C. p. Minodier 俞晓梅 Urgences pédiatriques CHU Nord chemin des Bourrelly 13915 Marseille Cedex 20 France

Aim of the study. -To describe epidemiological features of an outbreak of flu A in hospitalized children and to evaluate the flu’s burden in pediatric and p ediatric emergencies departments. population and methods. -Multicenter prospect ive study in 2 pediatric university hospitals, in Marseille, France. Nasal swabs for flu A were performed in all the febrile children admitted during winter 200 3-2004. pre and postoutbreak admissions in pediatric and pediatric emergencies departments were compared too. Results. -During the outbreak, 941 children were admitted and 605 were tested for flu A. Nasal swabs were positive in 111. Attac k’s rate was 11.8%. In these children, infants under 2 years were 66%. Respir atory forms were uncommon, although febrile seizures and digestive troubles were much frequent. The mean hospitalization duration was almost 4 days. Flu A outbr eak finally increased the pediatric and pediatric emergencies departments rates of admission, of 48%and 37%respectively. Conclusion. -Flu is frequently under estimated in children, especially in infants. Clinical forms are various. Child ’s vaccination is questionable in France.

关键词：甲型流感病毒儿科病房急诊室暴发负担费用季节性多中心前瞻性研究流行病学特征住院治疗

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