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JOURNAL OF SAFETY SCIENCE AND RESILIENCE 2024年第3期5卷 281-294页

作者： Hua, Ying Zhao, Jincheng Li, Hai-Ting duan, liping Shanghai Jiao Tong Univ Sch Ocean & Civil Engn Dept Civil Engn Shanghai 200240 Peoples R China Shanghai Jiao Tong Univ Shanghai Key Lab Digital Maintenance Bldg & Infras Shanghai 200240 Peoples R China

Staircase choice is one of the most critical factors leading to the difference in pedestrian flow and evacuation routes in buildings with multiple staircases. Neither the shortest path to the building exit nor the locally quickest path to the nearest staircase can represent the natural mode of evacuation path choices for an authentic evacuation simulation. Thus, a prediction-based approach is established to predict and simulate evacuation choices, which helps to address three key issues: (1) extracting evacuation data through a controlled experiment; (2) establishing a Logit model for staircase choice prediction based on experimental data; (3) developing a prediction-based cellular automaton model. The proposed approach has achieved the coupling between choice prediction and evacuation simulation. A comparison with Pathfinder software is conducted to reveal the superiority of the prediction-based CA model for simulating staircase choice.

关键词： Evacuation Staircase choice Prediction-based Logit Cellular automaton EXIT CHOICE MODEL

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伊立替康相关迟发性腹泻:肠道菌群视角

中华内科杂志 2024年第5期63卷 507-511页

作者：张庄宜段丽萍北京大学第三医院消化科北京100191

伊立替康是结直肠癌等恶性肿瘤重要的化疗药物。发生于用药24 h后的迟发性腹泻是伊立替康独特的不良反应,显著影响患者生活质量、限制化疗剂量、潜在影响化疗疗效。肠道菌群通过以肠菌来源的β-葡萄糖醛酸酶为核心的机制深度参与伊立替... 详细信息

伊立替康是结直肠癌等恶性肿瘤重要的化疗药物。发生于用药24 h后的迟发性腹泻是伊立替康独特的不良反应,显著影响患者生活质量、限制化疗剂量、潜在影响化疗疗效。肠道菌群通过以肠菌来源的β-葡萄糖醛酸酶为核心的机制深度参与伊立替康的体内代谢,影响迟发性腹泻的发生,是干预这一不良反应的潜在靶点。

关键词：伊立替康迟发性腹泻肠道菌群葡萄糖醛酸酶

中国特色教育领导制度优势转化的逻辑结构与机制创新

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国家教育行政学院学报 2024年第3期315卷 69-78页

作者：蒲蕊段丽萍华中师范大学湖北武汉430079

中国特色教育领导制度是党的领导制度体系的重要组成部分,蕴含着巨大的政治优势、组织优势和功能优势,这些优势能否高效地转化为教育治理效能,关涉到教育高质量发展、办好人民满意的教育以及立德树人根本任务的落实。教育领导制度优势... 详细信息

中国特色教育领导制度是党的领导制度体系的重要组成部分,蕴含着巨大的政治优势、组织优势和功能优势,这些优势能否高效地转化为教育治理效能,关涉到教育高质量发展、办好人民满意的教育以及立德树人根本任务的落实。教育领导制度优势要更好地转化为教育治理效能,需要把握好制度、主体、效能这三个关键性要素及其互动关系。教育领导制度是优势转化的依据和保障,治理行动和治理能力是制度优势转化的中介要素,教育治理效能是制度优势转化的结果。教育领导制度优势的更好转化需要创建价值引领、能力建设、协调运行、监督制约四个机制,从而使“善制”转向“善治”。

关键词：中国特色教育领导制度制度优势教育治理效能转化逻辑与机制

结直肠癌患者接受含伊立替康方案化疗后出现迟发性腹泻的临床特征及相关因素分析

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中华医学杂志 2024年第19期104卷 1680-1687页

作者：张庄宜曹宝山段丽萍北京大学第三医院消化科北京北京大学第三医院肿瘤化疗与放射病科北京

目的分析结直肠癌患者接受含伊立替康的化疗方案后, 发生迟发性腹泻的临床特征及相关因素。方法回顾性纳入2018年1月至2023年6月于北京大学第三医院接受抗肿瘤治疗的结直肠癌患者, 分析病历记录的全部包含伊立替康的化疗线, 收集有关临... 详细信息

目的分析结直肠癌患者接受含伊立替康的化疗方案后, 发生迟发性腹泻的临床特征及相关因素。方法回顾性纳入2018年1月至2023年6月于北京大学第三医院接受抗肿瘤治疗的结直肠癌患者, 分析病历记录的全部包含伊立替康的化疗线, 收集有关临床资料, 依据病程中是否发生过迟发性腹泻, 将患者分为腹泻组和无腹泻组;依据本轮化疗是否发生迟发性腹泻, 分为合并腹泻的化疗组和无腹泻的化疗组, 每1轮化疗视作1例次数据。统计迟发性腹泻的发生率及其临床特征。采用多因素logistic回归模型分析迟发性腹泻发生的相关因素。结果共纳入215例患者。腹泻组104例, 男57例, 女47例, 年龄23～83(58±12)岁;无腹泻组111例, 男73例, 女38例, 年龄32～83(58±10)岁。所有患者总计接受过271例次包含伊立替康的化疗线, 合并迟发性腹泻的化疗组有118例次(43.5%), 其中22例次(18.6%)为≥3级的严重腹泻。87例次(73.7%)腹泻事件发生于第1周期化疗后, 首次出现腹泻的中位时间[M(Q1, Q3)]为化疗后第4(3, 5)天。迟发性腹泻导致41例次(34.7%)化疗线后续延期或药物减量。化疗时年龄>65岁(OR=1.96, 95%CI:1.13～3.38)、方案含有三种化疗药物(OR=3.48, 95%CI:1.38～8.82)的患者发生任意级别腹泻的风险较高, 既往有结直肠癌肝转移切除术史(OR=0.51, 95%CI:0.27～0.95)的患者发生任意级别腹泻的风险较低(均P65岁、方案含有三种化疗药物的患者发生任意级别腹泻的风险较高, 既往有结直肠癌肝转移切除术史的患者发生任意级别腹泻的风险较低。

关键词：结直肠肿瘤迟发性腹泻伊立替康临床特征相关因素

“Sentinel or accomplice”:gut microbiota and microglia crosstalk in disorders of gut-brain interaction

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Protein & Cell 2023年第10期14卷 726-742页

作者： Haonan Zheng Cunzheng Zhang Jindong Zhang liping duan Department of Gastroenterology Peking University Third HospitalBeijing 100191China Beijing Key Laboratory for Helicobacter Pylori Infection and Upper Gastrointestinal Diseases Beijing 100191China

Abnormal brain-gut interaction is considered the core pathological mechanism behind the disorders of gut-brain interaction(DGBI),in which the intestinal microbiota plays an important *** are the“sentinels”of the central nervous system(CNS),which participate in tissue damage caused by traumatic brain injury,resist central infection and participate in neurogenesis,and are involved in the occurrence of various neurological *** in-depth research on DGBI,we could find an interaction between the intestinal microbiota and microglia and that they are jointly involved in the occurrence of DGBI,especially in individuals with comorbidities of mental disorders,such as irritable bowel syndrome(IBS).This bidirectional regulation of microbiota and microglia provides a new direction for the treatment of *** this review,we focus on the role and underlying mechanism of the interaction between gut microbiota and microglia in DGBI,especially IBS,and the corresponding clinical application prospects and highlight its potential to treat DGBI in individuals with psychiatric comorbidities.

关键词： gut microbiota microglia disorders of gut-brain interaction irritable bowel syndrome

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语义网赋能建筑信息交付及模型数据模式分析

土木与环境工程学报（中英文） 2024年第1期46卷 244-253页

作者：刘吉明段立平林思伟缪季赵金城上海交通大学船舶海洋与建筑工程学院上海200240 上海交通大学上海市公共建筑和基础设施数字化运维重点实验室上海200240

针对以建筑信息模型(BIM)进行交付的信息共享模式所依赖的工业基础类(IFC)标准行业适用性不足且难以拓展的问题,探讨在IFC基础上引入语义网实现异源数据集成共享,并于语义层面实现信息交付。首先,通过算法解析和模型转化介绍语义化建模... 详细信息

针对以建筑信息模型(BIM)进行交付的信息共享模式所依赖的工业基础类(IFC)标准行业适用性不足且难以拓展的问题,探讨在IFC基础上引入语义网实现异源数据集成共享,并于语义层面实现信息交付。首先,通过算法解析和模型转化介绍语义化建模方法,并以二层钢框架厂房结构为例对该方法进行说明;然后,通过对转化案例进行数据模式分析,以验证建筑信息交付的准确性和建筑语义的可传递性。案例实践论证基于IfcOWL本体的语义化建模方法的可实施性;通过分析该语义化模型单元实例的数据模式,探究制约该语义化建模方法赋能建筑信息交付的关键因素;针对语义化建模方法所面临的问题,提出冗余信息规避、领域本体开发和轻量化语义建模的初步解决思路。SPARQL查询实例表明,所解析的数据模式对规避冗余信息有效。因此,该方法在共享和集成建筑多源异构信息方面具有优势,能有效提升建筑信息管理的智能化水平。

关键词：建筑信息交付语义网数据模式分析工业基础类建筑信息模型

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KVPO_(4)F/carbon nanocomposite with highly accessible active sites and robust chemical bonds for advanced potassium-ion batteries

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Green Energy & Environment 2023年第5期8卷 1469-1478页

作者： Jianzhi Xu liping duan Jiaying Liao Haowei Tang Jun Lin Xiaosi Zhou School of Chemistry and Materials Science Nanjing Normal UniversityNanjing210023China

KVPO_(4)F(KVPF)has been extensively investigated as the potential cathode material for potassium-ion batteries(PIBs)owing to its high theoretical capacity,superior operating voltage,and three-dimensional Kt conduction ***,the electrochemical behavior of KVPF is limited by the inherent poor electronic conductivity of the phosphate framework and unstable electrode/electrolyte *** address the above issues,this work proposes an infiltration-calcination method to confine the in-situ grown KVPF into the mesoporous carbon CMK-3(denoted KVPF@CMK-3).The assembled KVPF@CMK-3 nanocomposite features three-dimensional interconnected carbon channels,which not only offer abundant active sites and significantly accelerate K t/electron transport,but also prevent the growth of KVPF nanoparticle agglomerates,hence stabilizing the structure of the ***,V–F–C bonds are created at the interface of KVPF and CMK-3,which reduce the loss of F and stabilize the electrode ***,when tested as a cathode material for PIBs,the KVPF@CMK-3 nanocomposite delivers superior reversible capacitiy(103.2 mAh g^(-1) at 0.2 C),outstanding rate performance(90.1 mAh g^(-1) at 20 C),and steady cycling performance(92.2 mAh g^(-1) at 10 C and with the retention of 88.2%after 500 cycles).Moreover,its potassium storage mechanism is further examined by ex-situ XRD and ex-situ XPS *** above synthetic strategy demonstrates the potential of KVPF@CMK-3 to be applied as the cathode for PIBs.

关键词： Potassium-ion batteries Cathode KVPO_(4)F CMK-3 V–F–C bond

基于贝叶斯优化XGBoost的建筑施工事故类型预测

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中国安全生产科学技术 2024年第5期20卷 57-63页

作者：缪季段立平刘吉明林思伟赵金城上海交通大学船舶海洋与建筑工程学院上海200240 上海市公共建筑和基础设施数字化运维重点实验室上海200240

为探究建筑工程施工过程中不同风险特征与施工事故类型之间的关联性,提出1种融合特征选择算法和机器学习算法的建筑事故类型预测模型。基于619项国内建筑事故报告建立建筑施工风险特征体系,通过条件互信息最大化(CMIM)-Boruta方法筛选... 详细信息

为探究建筑工程施工过程中不同风险特征与施工事故类型之间的关联性,提出1种融合特征选择算法和机器学习算法的建筑事故类型预测模型。基于619项国内建筑事故报告建立建筑施工风险特征体系,通过条件互信息最大化(CMIM)-Boruta方法筛选出26个关键风险特征,将其作为贝叶斯优化极限梯度提升(XGBoost)预测模型的输入变量并在测试集上评估该模型的预测精度。研究结果表明:XGBoost模型的预测性能优于其他机器学习模型;CMIM-Boruta方法和贝叶斯优化方法能够有效提升机器学习模型的预测性能;通过2个实际事故案例验证得到该模型具有一定实用性。研究结果对相关企业安全管理人员更准确地识别施工现场潜在危险、采取更具针对性的预防措施具有一定参考意义。

关键词：建筑工程事故预测特征选择机器学习贝叶斯优化

Synthesis of multicore-shell FeS_(2)@C nanocapsules for stable potassiumion batteries

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Journal of Energy Chemistry 2022年第10期31卷 126-132,I0004页

作者： Zhuangzhuang Zhang liping duan Yifan Xu Chuanfeng Zhao Jianchun Bao Jian Shen Xiaosi Zhou Jiangsu Key Laboratory of New Power Batteries Jiangsu Collaborative Innovation Center of Biomedical Functional MaterialsSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjing 210023JiangsuChina

Transition-metal sulfides are widely used as anodes for potassium-ion batteries(PIBs) due to their low cost and high theoretical *** practical application of such materials,however,is still impeded by their inherent low conductivity and obvious volume change during ***,a flexible etchassisted sulfidation strategy is *** to the strategy,the multicore-shell(MCS) nanocapsule structure is constructed,and then mesoporous FeS2 nanoparticles are encapsulated in the hollow carbon shell with adjustable interior *** product,MCS-FeS2@C-20,not only features optimized inner space,but also delivers a large reversible capacity(519 mAh g^(-1) at a current density of 50 mA g^(-1)),good rate capability(107 mAh g^(-1) at a high current density of 5 A g^(-1)) and excellent cycling stability(capacity retention rate of 84.2% over 500 cycles at 0.5 A g^(-1)),making it the promising anode material for ***,potassium-ion full cells(MCS-FeS_(2)@C-20//K_(0.4)CoO_(2)) also show an improved potassium storage performance.

关键词： Potassium-ion battery Anode FeS_(2) Yolk-shell structure Carbon protection

Coupling Ternary Selenide SnSb_(2)Se_(4) with Graphene Nanosheets for High-Performance Potassium-Ion Batteries

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Energy & Environmental Materials 2023年第4期6卷 280-288页

作者： Ruiqi Tian liping duan Yifan Xu Yuehua Man Jianlu Sun Jianchun Bao Xiaosi Zhou School of Chemistry and Materials Science Nanjing Normal UniversityNanjing 210023China

Although chalcogenide anodes possess higher potassium storage capacity than intercalated-based graphite,their drastic volume change and the irreversible electrochemical reactions still hinder the effective electron/ion transfer during the potassiation/depotassiation *** solve the above problems,this article proposes the synthesis of a lamellar nanostructure where graphene nanosheets are embedded with SnSb_(2)Se_(4)nanoparticles(SnSb_(2)Se_(4)/GNS).In the product,fine monodisperse SnSb_(2)Se_(4)nanoparticles are coupled with graphene nanosheets to form a porous network framework,which can effectively mitigate the drastic volume changes during electrode reactions and guarantee efficient potassium-ion storage through the synergistic interactions among multiple *** electrochemical analyses prove that SnSb_(2)Se_(4)inherits the advantages of the binary Sb2Se3 and SnSe while avoiding their disadvantages,confirming the synergistic effect of the ternary–chalcogenide *** tested for potassium storage,the obtained composite delivers a high specific capacity of 368.5 mAh g^(-1)at 100 mA g^(-1)and a stable cycle performance of 265.8 mAh g^(-1)at 500 mA g^(-1)over 500 ***,the potassium iron hexacyanoferrate cathode and the SnSb_(2)Se_(4)/GNS anode are paired to fabricate the potassium-ion full cell,which shows excellent cyclic *** conclusion,this strategy employs atomic doping and interface interaction,which provides new insights for the design of high-rate electrode materials.

关键词： anode ex situ XRD potassium-ion battery SnSb_(2)Se_(4) synergistic effect