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The Radiation Damage Mechanism of Rare Earth Doped BaF_2 Crystals

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Chinese journal of nuclear physics 1994年第4期 359-363页

作者： du jie chen ling-yan (Department of Physics,Tongji University,Shanghai 200092)chen gang ren shao-xia (Beijing Glass Research Institute,Beijing 100062)

The Discrete variation Xα（DV-Xα）method was used to calculate the energylevel of some rare earth doped BaF2 *** results indicated that elements Eu,Dyand Yb will change their valence from +3 to +2 under irradiation and thus change theoptical properties of the *** calculation using radiation damage model agreeswell with experiments.

关键词： Radiation damage Rare earth Doped BaF2 crystal

FAST VLBI: current status and future plans

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Research in Astronomy and Astrophysics 2020年第5期20卷 165-170页

作者： Ru-Rong chen Hai-yan Zhang cheng-Jin Jin Zhi-Shen Gao yan Zhu Kai Zhu Peng Jiang You-ling Yue Ji-Guang Lu Bo Zhang Wu Jiang ren-jie Zhu shao-Guang Guo Bo xia Rong-Bing Zhao FAST Collaboration National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China CAS Key Laboratory of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China

The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the largest single-dish radio telescope in the world,and is now being commissioned after the first light in September *** long baseline interferometry(VLBI)is among the key science topics according to the original *** FAST VLBI system has been established,and the first VLBI fringe has been successfully *** will significantly improve the sensitivity of the existing VLBI networks in the future,and some science projects in need of high sensitivity will benefit from its participation.

关键词： instrumentation:interferometers telescopes site testing

Atherogenic index of plasma combined with waist circumference and body mass index to predict metabolic-associated fatty liver disease

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World Journal of Gastroenterology 2022年第36期28卷 5364-5379页

作者： shao-jie duan Zhi-Ying ren Tao Zheng Hong-Ye Peng Zuo-Hu Niu Hui xia Jia-Liang chen Yuan-chen Zhou Rong-Rui Wang Shu-Kun Yao Graduate School Beijing University of Chinese MedicineBeijing 100029China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Graduate school Peking University China-Japan Friendship School of Clinical MedicineBeijing 100029China Department of Gastroenterology China-Japan Friendship HospitalBeijing 100029China

BACKGROUND Early identification of metabolic-associated fatty liver disease(MAFLD)is *** index of plasma(AIP)is a reference predictor of obesity-related diseases,but its predictive value for MAFLD remains *** studies have reported whether its combination with waist circumference(WC)and body mass index(BMI)can improve the predictive performance for *** To systematically explore the relationship between AIP and MAFLD and evaluate its predictive value for MAFLD and to pioneer a novel noninvasive predictive model combining AIP,WC,and BMI while validating its predictive performance for *** This cross-sectional study consecutively enrolled 864 *** logistic regression analysis and receiver operating characteristic curve were used to evaluate the relationship between AIP and MAFLD and its predictive power for *** novel prediction model A-W-B combining AIP,WC,and BMI to predict MAFLD was established,and internal verification was completed by magnetic resonance imaging *** Subjects with higher AIP exhibited a significantly increased risk of MAFLD,with an odds ratio of 12.420(6.008-25.675)for AIP after adjusting for various confounding *** area under receiver operating characteristic curve of the A-W-B model was 0.833(0.807-0.858),which was significantly higher than that of AIP,WC,and BMI(all P<0.05).Subgroup analysis illustrated that the A-W-B model had significantly higher area under receiver operating characteristic curves in female,young and nonobese subgroups(all P<0.05).The best cutoff values for the A-W-B model to predict MAFLD in males and females were 0.5932 and 0.4105,***,in the validation set,the area under receiver operating characteristic curve of the A-W-B model to predict MAFLD was 0.862(0.791-0.916).The A-W-B level was strongly and positively associated with the liver proton density fat fraction(r=0.630,P<0.001)and significantly increased with the sever

关键词： Atherogenic index of plasma Metabolic-associated fatty liver disease Receiver operating characteristic curve Predictor

Loss of Light Yield of Doped Lead Tungstate Crystals After Irradiation

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Chinese Physics Letters 1999年第10期16卷 745-746页

作者： HE Jing-tang LU Yu-sheng chen duan-bao LI Zu-hao BIAN Jian-guo ZHU Guo-yi TANG xiao-wei chen gang ZHENG Lian-rong chen xiao-hong ren shao-xia Institute of High Energy Physics Chinese Academy of SciencesBeijing 100039 Beijing Inorganic Crystal Laboratory Beijing Glass Research InstituteBeijing 100062

Loss of light yield of doped lead tungstate crystals after irradiation with a low dose rate has been *** La,Pr,and Y doping may improve radiation hardness,whereas Bi or Mo doping is harmful.

关键词： doping state Crystal

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin chen Danping chen Fuqing chen Fusan chen gang chen Guoming chen Hua-Xing chen Huirun chen Jinhui chen Ji-Yuan chen Kai chen Mali chen Mingjun chen Mingshui chen Ning chen Shanhong chen Shanzhen chen shao-Long chen shaomin chen Shiqiang chen Tianlu chen Wei chen xiang chen xiaoyu chen Xin chen Xun chen Xurong chen Ye chen Ying chen Yukai chen Zelin chen Zilin chen gang chen Boping chen Chunhui chen Hok Chuen cheng Huajie cheng Shan cheng Tongguang cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

肘关节造影闭合复位经皮克氏针固定治疗儿童肱骨外髁骨折

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临床骨科杂志 2024年第1期27卷 66-69页

作者：任小军苏春红陈永刚移志刚丁界先刘文忠董平夏亚一兰州大学第二医院骨科甘肃兰州730000 兰州大学第二医院疼痛科甘肃兰州730000

目的探讨肘关节造影闭合复位经皮克氏针固定治疗儿童肱骨外髁骨折的疗效。方法采用肘关节造影闭合复位经皮克氏针固定治疗24例肱骨外髁骨折患儿。记录骨折愈合情况、并发症发生情况、肘关节恢复情况,末次随访时采用Flynn肘关节评分标准... 详细信息

目的探讨肘关节造影闭合复位经皮克氏针固定治疗儿童肱骨外髁骨折的疗效。方法采用肘关节造影闭合复位经皮克氏针固定治疗24例肱骨外髁骨折患儿。记录骨折愈合情况、并发症发生情况、肘关节恢复情况,末次随访时采用Flynn肘关节评分标准评价疗效。结果患儿均获得随访,时间18~24个月。骨折均愈合,时间8~16周。术后未发生肘外翻畸形、肱骨外髁缺血性坏死、骨化性肌炎、缺血性肌挛缩以及神经症状等并发症。末次随访时,4例患儿肘关节功能未完全恢复正常,但不影响生活,Flynn肘关节评分等级均为良;20例肘关节功能均恢复至健侧水平,Flynn肘关节评分等级均为优。结论采用肘关节造影闭合复位经皮克氏针固定治疗儿童肱骨外髁骨折,术中能清楚显示儿童肱骨远端的软骨成分,有助于判断骨折的移位程度和闭合复位的质量,避免不必要的切开复位及并发症的发生。

关键词：肘关节造影闭合复位经皮固定儿童肱骨外髁骨折

喷雾干燥-高温热处理两步法制备YAG∶Ce^(3+)荧光粉

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功能材料 2010年第11期41卷 1944-1947页

作者：陈少云曾人杰陈毅彬郜盛夏厦门大学材料学院福建厦门361005

以喷雾干燥-高温热处理两步法,由含聚合铝阳离子的前驱体悬浊液,制得了YAG∶Ce3+荧光粉。用XRD、SEM、荧光光谱等研究了热处理温度、前驱体悬浊液浓度对YAG晶相的形成、粉末颗粒形貌及发光性能的影响。发现前驱体悬浊液浓度由0.03mol/L... 详细信息

以喷雾干燥-高温热处理两步法,由含聚合铝阳离子的前驱体悬浊液,制得了YAG∶Ce3+荧光粉。用XRD、SEM、荧光光谱等研究了热处理温度、前驱体悬浊液浓度对YAG晶相的形成、粉末颗粒形貌及发光性能的影响。发现前驱体悬浊液浓度由0.03mol/L提高到0.09mol/L时,热处理后所得荧光粉颗粒尺寸增大,并趋近球形;前驱体悬浊液浓度为0.09mol/L,热处理温度从1300℃提高到1500℃时,荧光粉相对亮度提高。YAG∶Ce3+粉末900℃热处理2h可获YAG相;所制备的YAG∶Ce3+荧光粉颗粒无空心,团聚程度低。

关键词：固相反应烧结晶体长大白光LED 钇铝石榴石

Oridonin induces apoptosis in gastric cancer through Apaf-1,cytochrome c and caspase-3 signaling pathway

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World Journal of Gastroenterology 2012年第48期18卷 7166-7174页

作者： Ke-Wang Sun Ying-Yu Ma Tian-Pei Guan Ying-jie xia Chang-Ming shao Le-Gao chen Ya-Jun ren Hai-Bo Yao Qiong yang Xu-Jun He Department of Thyroid and Breast Surgery Zhejiang Provincial People's Hospital Key Laboratory of Gastroenterology of Zhejiang Province Zhejiang Provincial People's Hospital Surgical Department Wenzhou Medical College Surgical Department Zhejiang Chinese Medical University

AIM:To investigate the effect and mechanism of oridonin on the gastric cancer cell line HGC-27 in ***:The inhibitory effect of oridonin on HGC-27 cells was detected using the 3-(4,5-dimethylthiazol2-yl)-2,5-diphenyl tetrazolium bromide *** treatment with 10 μg/mL oridonin for 24 h and 48 h,the cells were stained with acridine orange/ethidium *** morphologic changes were observed under an inverted fluorescence *** fragmen-tation(a hallmark of apoptosis) and lactate dehydrogenase activity were examined using DNA ladder assay and lactate dehydrogenase-release *** treated with oridonin(0,1.25,2.5,5 and 10 μg/mL),HGC-27 cells were collected for anexin V-phycoerythrin and 7-amino-actinomycin D double staining and tested by flow cytometric analysis,and oridonin-induced apoptosis in HGC-27 cells was *** treatment with oridonin for 24 h,the effects of oridonin on expression of Apaf-1,Bcl-2,Bax,caspase-3 and cytochrome c were also analyzed using reverse-transcript polymerase chain reaction(RT-PCR) and Western ***:Oridonin significantly inhibited the proliferation of HGC-27 cells in a dose-and time-dependent *** inhibition rates of HGC-27 treated with four different concentrations of oridonin for 24 h(1.25,2.5,5 and 10 μg/mL) were 1.78% ± 0.36%,4.96% ± 1.59%,10.35% ± 2.76% and 41.6% ± 4.29%,respectively,which showed a significant difference(P rence(P rence(P < 0.05).Cells treated with oridonin showed typical apoptotic features with acridine orange/ethidium bromide *** treatment with oridonin,the cells became round,shra

关键词： Oridonin Gastric cancer Proliferation Apoptosis Apaf-1/caspase-3/cytochrome C

马兜铃酸肾病肾移植术后泌尿系统并发尿路上皮癌8例临床分析

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解放军医学杂志 2010年第4期35卷 442-444页

作者：肖龙仁杨亦荣夏鹏郑少玲陈琰沈龙捷温州医学院附属第一医院移植中心浙江温州325000

目的总结马兜铃酸肾病(AAN)患者肾移植术后泌尿系统并发恶性肿瘤的临床特点及治疗体会。方法回顾分析2000年3月-2009年10月,28例AAN终末期肾功能衰竭患者同种异体肾移植术后泌尿系统并发恶性肿瘤发病特点、治疗及预后情况。28例AAN患者... 详细信息

目的总结马兜铃酸肾病(AAN)患者肾移植术后泌尿系统并发恶性肿瘤的临床特点及治疗体会。方法回顾分析2000年3月-2009年10月,28例AAN终末期肾功能衰竭患者同种异体肾移植术后泌尿系统并发恶性肿瘤发病特点、治疗及预后情况。28例AAN患者肾移植术后并发尿路上皮癌8例(28.6%),肿瘤均发生于受者自体泌尿系统,男4例,女4例,年龄35～68岁,平均52岁,患者移植术前均有明确AAN病史,均行血液透析治疗。发现肿瘤距移植时间为11～72个月,平均31个月。以反复发作全程肉眼血尿为首发症状者7例,体检偶然发现1例。病理结果均为尿路上皮癌,其中膀胱癌4例,左肾盂及双侧输尿管癌1例,双侧输尿管及膀胱癌1例,右肾盂输尿管癌1例,右肾盂及膀胱癌1例。患者均行手术治疗,肿瘤切除术后更换免疫抑制方案。对于膀胱癌患者术后予重组人α-2b干扰素+表阿霉素膀胱灌注化疗。结果本组8例患者手术顺利,术后肿瘤复发率为62.5%(5/8),术后随访8～72个月,平均32个月。除1例因发生移植肾急性排斥反应,移植肾切除后恢复血液透析,1例因移植肾功能减退恢复血液透析,后死于脑栓塞,其余6例肾功能正常,随访至今。结论ANN患者肾移植术后自体泌尿系统并发尿路上皮癌发病率高,且肿瘤呈多发性,复发率高。对发生尿路上皮癌的患者,在切除肿瘤的同时,应行双侧上尿路根治性切除术。

关键词：马兜铃酸肾移植尿路上皮癌