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食管癌术后重症肺炎患者血清肺表面活性物质相关蛋白质-D、高迁移率族蛋白B1和中性粒细胞与淋巴细胞比值水平变化及检测意义

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陕西医学杂志 2024年第8期53卷 1114-1117,1123页

作者：张少锋李丹青杜凡魏志强王海军邢台市人民医院胸外科河北邢台054001

目的:探讨中性粒细胞与淋巴细胞比值(NLR)、肺表面活性物质相关蛋白质-D(SP-D)及高迁移率族蛋白B1(HMGB1)在食管癌术后重症肺炎(SP)患者中的水平变化及检测意义。方法:选取接受手术治疗的食管癌患者257例,根据手术治疗后是否发生SP将患... 详细信息

目的:探讨中性粒细胞与淋巴细胞比值(NLR)、肺表面活性物质相关蛋白质-D(SP-D)及高迁移率族蛋白B1(HMGB1)在食管癌术后重症肺炎(SP)患者中的水平变化及检测意义。方法:选取接受手术治疗的食管癌患者257例,根据手术治疗后是否发生SP将患者分为SP组(124例)和对照组(133例)。比较两组血清SP-D、HMGB1和NLR水平。记录SP组患者28 d内预后情况,根据28 d内生存情况将SP组患者分为生存组(104例)和病死组(20例)。比较两组一般资料及实验室指标,采用Logistic回归分析食管癌术后SP患者预后影响因素。绘制受试者工作特征(ROC)曲线分析NLR、SP-D及HMGB1对食管癌术后SP患者28 d内病死风险的预测价值。结果:SP组血清SP-D及HMGB1和NLR水平高于对照组(均P<0.05)。病死组NLR、SP-D及HMGB1水平高于生存组(均P<0.05)。NLR、SP-D及HMGB1是食管癌术后SP患者病死的影响因素(均P<0.05)。NLR、SP-D及HMGB1预测食管癌术后SP患者28 d内病死风险的AUC分别为0.744、0.763、0.715,而三者联合检测的AUC更高(均P<0.05)。结论:食管癌术后SP患者NLR、SP-D及HMGB1水平升高,且与患者预后有关,三者联合检测有助于提升对患者病死风险的预测价值。

关键词：食管癌重症肺炎中性粒细胞与淋巴细胞比值肺表面活性物质相关蛋白质-D 高迁移率族蛋白B1 预后

高原地区试用温室型多介质人工湿地处理污水运行效果分析

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皮革制作与环保科技 2024年第9期5卷 148-150页

作者：白玛旺堆巴桑罗布德吉央宗漆胜群杜帆西藏自治区生态环境监测中心西藏山南850000 阿里地区生态环境监测中心西藏阿里859000 黑龙江省绥化生态环境监测中心黑龙江绥化152000

从西藏自治区县域生活污水的特点及居民的生活习惯出发,构建处理能力为1 000 m3/d的温室型多介质人工湿地示范工程,通过温室型多介质人工湿地与室外水平潜流人工湿地的组合工艺处理县域生活污水,以实现对该区域生活污水的净化,并用于补... 详细信息

从西藏自治区县域生活污水的特点及居民的生活习惯出发,构建处理能力为1 000 m3/d的温室型多介质人工湿地示范工程,通过温室型多介质人工湿地与室外水平潜流人工湿地的组合工艺处理县域生活污水,以实现对该区域生活污水的净化,并用于补充附近水环境的生态用水。监测数据表明,温室内多介质人工湿地整个运行期间COD平均出水浓度为40.92 mg/L、氨氮平均出水浓度为4.28 mg/L、总氮平均出水浓度为8.20 mg/L、总磷平均出水浓度为0.40 mg/L,出水质量高于《城镇污水处理厂污染物排放标准(GB 18918—2002)》(以下简称《标准》)一级A标准。系统有效克服了西藏地区高寒缺氧的气候条件,具有高效、稳定的去污性能。另外,室外潜流人工湿地最终COD(28.02 mg/L)、总磷(0.24 mg/L)出水水质均达到《地表水环境质量标准》(GB 3838—2002)的Ⅳ类标准。鉴于氮磷元素是植物生长的必需元素,工程出水可回用补充湿地。本工程的运行成功对于西藏自治区县域污水的人工湿地处理具有一定的工程示范作用和推广应用价值。

关键词：多介质人工湿地温室示范工程西藏地区净化效果

Impact crater recognition methods:A review

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Science China Earth Sciences 2024年第6期67卷 1719-1742页

作者： Dong CHEN fan HU Liqiang ZHANG Yunzhao WU Jianli du Jiju PEETHAMBARAN College of Civil Engineering Nanjing Forestry UniversityNanjing 210037China Department of Geography State Key Laboratory of Remote Sensing ScienceFaculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China Key Laboratory of Space Object and Debris Observation Chinese Academy of SciencesNanjing 210023China Department of Mathematics and Computing Science Saint Mary’s UniversityHalifaxNS B3H 3C3Canada

Impact craters are formed due to the high-speed collisions between small to medium-sized celestial *** is the most significant driving force in the evolution of celestial bodies,and the impact craters provide crucial insights into the formation,evolution,and impact history of celestial *** this paper,we present a detailed review of the characteristics of impact craters,impact crater remote sensing data,recognition algorithms,and applications related to impact *** first provide a detailed description of the geometric texture,illumination,and morphology characteristics observed in remote sensing data of *** we summarize the remote sensing data and cataloging databases for the four terrestrial planets(i.e.,the Moon,Mars,Mercury,and Venus),as well as the impact craters on ***,we study the advancement achieved in the traditional methods,machine learning methods,and deep learning methods applied to the classification,segmentation,and recognition of impact ***,based on the analysis results,we discuss the existing challenges in impact crater recognition and suggest some ***,we explore the implementation of impact crater detection algorithms and provide a forward-looking perspective.

关键词： Terrestrial planets Deep space exploration Impact crater Impact crater recognition Deep learning

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ACP100堆芯围板组件焊接变形研究

东方电气评论 2024年第4期38卷 35-37页

作者：王盛唐炼浦春梅舒华安杜凡刘杨孙诗扬东方电气集团东方电气(武汉)核设备有限公司武汉430223

ACP100模块式小型堆堆芯围板组件为一体化焊接结构,类似结构国内首次制造。针对新型堆芯围板组件结构特点,选择合适的焊接方法、焊接顺序,设置专用防变形工装。根据各工艺阶段焊接变形数据,总结分析了堆芯围板组件焊接变形规律,同时为... 详细信息

ACP100模块式小型堆堆芯围板组件为一体化焊接结构,类似结构国内首次制造。针对新型堆芯围板组件结构特点,选择合适的焊接方法、焊接顺序,设置专用防变形工装。根据各工艺阶段焊接变形数据,总结分析了堆芯围板组件焊接变形规律,同时为后续类似结构堆芯围板组件的制造提供了数据参考。

关键词： ACP100 堆芯围板组件焊接变形

Local search yields a PTAS for fixed-dimensional k-means problem with penalties

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Journal of the Operations Research Society of China 2024年第2期12卷 351-362页

作者： fan Yuan Da-Chuan Xu Dong-Lei du Dong-Mei Zhang Beijing Institute for Scientific and Engineering Computing Beijing University of TechnologyBeijing 100124China Faculty of Management University of New BrunswickFrederictonNB E3B 9Y2Canada School of Computer Science and Technology Shandong Jianzhu UniversityJinan 250101ShandongChina

We study a problem called the k-means problem with penalties(k-MPWP),which is a natural generalization of the typical k-means *** this problem,we have a set D of client points in R^(d),a set F of possible centers in R^(d),and a penalty cost Pj>O for each point j∈*** are also given an integer k which is the size of the center point *** want to find a center point set S■F with size k,choose a penalized subset of clients P■D,and assign every client in D\P to its open *** goal is to minimize the sum of the squared distances between every point in D\P to its assigned centre point and the sum of the penalty costs for all clients in *** using the multi-swap local search technique and under the fixed-dimensional Euclidean space setting,we present a polynomial-time approximation scheme(PTAS)for the k-MPWP.

关键词： Approximation algorithm k-means Local search Penalty

Effectiveness of Tenofovir Alafenamide in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase and Positive Hepatitis B Virus DNA

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Journal of Clinical and Translational Hepatology 2022年第1期10卷 112-119页

作者： Wen-Kang Gao Yan-Yun Shu Yue Chen Yan Ai Xiao-Qian Yang fan du Jin Ye Division of Gastroenterology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina

Background and Aims:With an increasing understanding of hepatitis B,the antiviral indications have been broadening *** evaluate the effectiveness of tenofovir alafena-mide(TAF)in chronic hepatitis B(CHB)patients with normal alanine aminotransferase(ALT)and detectable hepatitis B virus(HBV)DNA,those who are ineligible for broader anti-viral criteria from the Chinese CHB prevention guide(2019).Methods:A total of 117 patients were recruited and their data were collected from paper or electronic medical *** DNA and liver function were measured at baseline and throughout the 24-week *** effectiveness end-point was complete virological *** safety endpoint was the first occurrence of any clinical adverse event during the ***:Among the 117 patients,45 had normal ALT as well as detectable HBV DNA and they were not recommended for antiviral therapy according to Chinese Guidelines(2019).After TAF antiviral therapy,the rates of patients who achieved HBV DNA<20 IU/mL at 4,12 and 24 weeks were 77.1%,96.7%and 96.8%*** them,the undetectable rates of HBV DNA in patients with low baseline viral load at 4,12 and 24 weeks were 92.3%,100%and 100%,while the rates of those with high baseline viral load were 68.2%,94.1%and 94.4%.Compared with 71.4%,94.4%and 94.7%in the high baseline group,the undetectable rates of HBV DNA at 4,12 and 24 weeks in the low baseline liver stiffness group were 85.7%,100%and 100%.There was no statistical significance among the above ***:CHB patients who had normal ALT and detectable HBV DNA and did not meet“CHB prevention guide(2019)”,could achieve complete virological response in 24 weeks after antiviral treatment by TAF.

关键词： Chronic hepatitis B virus Tenofovir alafenamide Effectiveness Observational study

CD4+ cells as a potential biomarker for cytomegalovirus retinitis in children with acute lymphocytic leukemia

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Chinese Medical Journal 2019年第3期132卷 356-359页

作者： Jian-Cang Wang Fei-fan du Ming Su Xiao-Ge Yang Mei-Jie Quan Xiao-Ying Zhai Department of Ophthalmology Hebei Children's HospitalHebei Medical UniversityShijiazhuangHebei 050031China Department of Hematology Hebei Children's HospitalHebei Medical UniversityShijiazhuangHehei 050031China

To the Editor: Infection is one of the causes of death after chemotherapy in children with leukemia. About 20% to 30% acute lymphocytic leukemia (ALL) patients die from infection after chemotherapy.[1] Patients with immune deficiency, under chemotherapy, or treated with immunosuppressor are more inclined to be infected with human cytomegalovirus (HCMV) which leads to severe systematic disorders.[2] Cytomegalvirus retinitis (CMVR) is a major sight threatening disease which mainly occurs in patients with immune deficiency and results in blindness if treatment is delayed. The decrease of CD4+ T cells has been related to CMVR in immune deficiency syndrome like AIDS.[3] However, little is known about the relation between the level of T cells with different markers and the onset of CMVR in ALL patients under chemotherapy. Therefore, this study was designed to investigate the diagnostic value of T cells with different markers for cytomegalovirus retinitis after chemotherapy in patients with ALL.

关键词： cytomegalovirus retinitis acute lymphocytic leukemia CD4+ cells

Significant contribution of carbonyls to atmospheric oxidation capacity(AOC)during the winter haze pollution over North China Plain

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Journal of Environmental Sciences 2024年第5期139卷 377-388页

作者： Xue Yang Gen Zhang Guang Pan Guolan fan Houyong Zhang Xuan Ge Mingyue du School of Municipal and Environmental Engineering Shandong Jianzhu UniversityJi’nan 250101China State Key Laboratory of Severe Weather&Key Laboratory of Atmospheric Chemistry of China Meteorological Administration Chinese Academy of Meteorological SciencesBeijing 100081China Shandong Jinan Ecological Environment Monitoring Center Ji’nan 250101China

Atmospheric carbonyl compounds play significant roles in the cycling of radicals and have exhibited surprisingly high levels in winter that were well correlated to particulate matter,for which the reason have not been clearly *** we measured carbonyl compounds and other trace gasses together with PM_(2.5)over urban Jinan in North China Plain during the *** higher carbonyl concentrations(average:14.63±4.21 ppbv)were found during wintertime haze pollution,about one to three-times relative to those on nonhaze days,with slight difference in chemical composition except formaldehyde(HCHO).HCHO(3.68 ppbv),acetone(3.17 ppbv),and acetaldehyde(CH_3CHO)(2.83 ppbv)were the three most abundant species,accounting for~75% of the total carbonylson both haze and non-haze *** from observational-based model(OBM)with atmospheric oxidation capacity(AOC)indicated that AOC significantly increased with the increasing carbonyls during the winter haze *** photolysis have supplied key oxidants such as RO_(2) and HO_(2),and thereby enhancing the formation of fine particles and secondary organic aerosols,elucidating the observed haze-carbonyls *** variation with carbonyls exhibiting peak values at early-noon and night highlighted the combined contribution of both secondary formation and primary diesel-fuel sources.1-butene was further confirmed to be the major precursor for *** study confirms the great contribution of carbonyls to AOC,and also suggests that reducing the emissions of carbonyls would be an effective way to mitigate haze pollution in urban area of the NCP region.

关键词： Carbonyls Haze Observation-based model Source apportionment Atmospheric oxidation capacity

Highly active and durable La_(0.6) Ca_(0.4)(CrMnFeCo_(2)Ni)O_(3) high entropy perovskite oxide as electrocatalyst for oxygen evolution reaction in alkaline media

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Journal of Materials Science & Technology 2024年第1期168卷 71-78页

作者： Xiaoqiang Ji fan Yang Yunzhu du Jing Li Jianguo Li Qiaodan Hu Shanghai Key Laboratory of Materials Laser Processing and Modification School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Oxygen evolution reaction(OER)is the imperative reaction for many energy storage and conversion devices such as recharge-able metal-air batteries and electrochemical water splitting[1].OER is a complex 4-electron process with sluggish kinetics and therefore requires electrocatalysts to overcome the high *** oxide(RuO_(2))and iridium oxide(IrO_(2))catalysts can promote the OER process remarkably[2-4],however,their ex-tremely high cost,natural scarcity,and long-term instability con-strain their scale-up application in clean-energy technologies[5,6].It is crucial to develop inexpensive,highly efficient,and durable electrocatalysts for OER.

关键词： entropy alkaline perovskite