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Percutaneous Coronary Intervention in Acute Coronary Syndromes at the Mother-Child University Hospital Luxembourg in Bamako

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World Journal of Cardiovascular Diseases 2024年第4期14卷 288-294页

作者： Mamadou toure Hamma Sankare Baba I. Diarra Mariam Dagnogo Modibo doumbia Abdoul W. terra Samba Sidibe coumba A. t.iam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane traore Daouda Fofana Almou A. Diall Mady Sow Massama Konate Hamidou O. Ba Ichaka Menta Cardiology Department CHU-Mother Child Bamako Mali Cardiology Department CHU-Gabriel Tour&#233 Bamako Mali Faculty of Medicine University of Sciences Techniques and Technologies of Bamako Bamako Mali Department of Cardiac Surgery Center Andre FESTOC Bamako Mali Cardiology Department CHU-Point G Bamako Mali

Introduction: Acute coronary syndromes (ACS) are a diagnostic and therapeutic emergency. Objective: Studying the feasibility, difficulties and results of coronary angioplasty in acute coronary syndromes at the Luxembourg Mother-Child University Hospital in Bamako. Patients and Methods: Cross-sectional, descriptive study with prospective recruitment over 18 months from September 2020 to February 2022. All patients aged at least 18 years old admitted for SCA and having undergone PCI during the study period were included. Result: We collected 249 patients for SCA, of whom 160 underwent angioplasty, either an angioplasty/SCA ratio of 0.64. the average age of the patients was 59.54 ± 11.62 with extremes of 32 and 92 years. the age group of 45 to 65 years was the most representative. the predominance was male, sex ratio of 2.4. the main cardiovascular risk factors were high blood pressure (58.23%) and diabetes (45.78%). Persistent St-segment elevation on the electrocardiogram was present in 71.48%. the treatment time was more than 12 hours after the first medical contact in 95.5%. the approach was radial in 96.5% of cases. Coronarography was pathological in 91.16% of our patients. the lesions were tri-truncular in 34.13% with the anterior inter ventricular as culprit artery in 72% of cases. the majority of patients (64%) had undergone angioplasty with implantation of an active stent. Angioplasty was performed successfully in 98% and per procedural mortality was 1.87%. Only 6.45% of ACS with St elevation benefited from primary angioplasty. Conclusion: Percutaneous coronary intervention is performed routinely in our center with satisfactory results. Difficulties exist, related to the diagnostic delay of ACS and the high cost of angioplasty.

关键词： Acute Coronary Syndromes Coronary Angiography Angioplasty Mother-Child University Hospital Luxembourg Bamako Mali

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Acute Coronary Syndrome of Young Subjects at the Luxembourg Mother-Child University Hospital in Bamako

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World Journal of Cardiovascular Diseases 2024年第3期14卷 157-165页

作者： Mamadou toure Mariam Dagnogo Massama Konate Mariam Sako Daouda Fofana Hamma Sankare Almou A. Diall Modibo doumbia Baba I. Diarr Mady Sow Abdoul Wahhab terra coumba A. t.iam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane traore Hamidou O. Ba Ichaka Menta Cardiology Department CHU-Mother Child Bamako Mali Cardiology Department CHU-Gabriel Tour&#233 Bamako Mali Faculty of Medicine University of Sciences Technics and Technologies of Bamako Bamako Mali Center Andre FEStOC Department of Cardiac Surgery of Bamako Mali Bamako Mali

Introduction: Acute coronary syndrome is often the first event of coronary disease of young subjects. Objective: to study sociodemographic, clinical, paraclinical, therapeutic and evolutionary aspects of acute coronary syndrome of young subjects. Patients and Methods: Descriptive cross-sectional study with prospective recruitment from October 01, 2020 to March 31, 2022. Were included all patients admitted for acute coronary syndrome whose age was less or equal to 45 years and who had undergone coronary angiography at the Mother-Child University Hospital on Luxembourg from Bamako. Results: During the study period, we collected 60 patient files out of 198. these 60 patient files met our inclusion criteria. Hospital frequency was 30.30%. Average age of patients was 40.43 ± 3.9 years. Sex ratio M/F was 5.3. Main cardiovascular risk factor was smoking tobacco (23.42%), followed by dyslipidemia (13.92%). Functional signs were dominated by angina 62% followed by dyspnea 25.3%. Persistent St-segment elevation on electrocardiogram was present in 76.4%. Left ventricular systolic dysfunction was present in 26.5%. time to first medical contact was more than 12 hours in 62.7% of cases. Radial approach was adopted in 94% of cases. Coronary angiography was pathological in 85% (n = 51) of cases. Lesions were single-vessel disease in 47.1% and culprit artery was anterior interventricular in 51% of cases. Dual anti-platelet aggregation was aspirin and ticagrelor in 91.8% of cases. Angioplasty was performed in all patients who had significant abnormalities at coronary angiography. In-hospital mortality was 3.9%. Conclusion: Acute coronary syndromes exist in young Africans with a male predominance. Main cardiovascular risk factor is smoking tobacco. Coronary lesions are single vessel disease in the majority of case. Most of patients meet medical team after 12 hours. time to first medical contact is a main challenge in our country.

关键词： Acute Coronary Syndrome Young Subjects Coronary Angiography CHU Luxembourg Bamako

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Screening, treatment and Control of High Blood Pressure on Five Sites in Mali

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World Journal of Cardiovascular Diseases 2024年第5期14卷 322-332页

作者： Mamadou touré Sagara Ibrahima Youssouf Camara Hamidou Oumar Bâ Ibrahima Sangaré Djénébou traoré Noumou Sidibé Fousseyni Samassékou Massama Konaté coumba t.iam doumbia Asmaou Maiga Réné-Marie Dakouo Hamidou Camara Sako Mariam Sidibé Samba Adama Sogodogo Boubacar Diarra Boubacar Sonfo Aladji traoré Mamadou Diakité Ilo Bella Diall Ichaka Menta Departement of Cardiology University Hospital Gabriel Tour&#233 Bamako Mali Departement of Cardiology Cardiology University Hospital Sidy Bocar Sall Kati Mali Internal Medecine University Hospital Point G Bamako Mali Departement of Cardiology Cardiology University Hospital &#8220H&#244pital du Mali&#8221 Bamako Mali Departement of Cardiology Cardiology University Hospital Mother-Children Bamako Mali

Introduction: High blood pressure is defined as blood pressure greater than or equal to 140 mm Hg for systolic and or 90 mm Hg for diastolic. It constitutes a major public health problem, the leading chronic disease in the world. the objective was to determine the prevalence, treatment rate and control of hypertension. Methods: this was a cross-sectional and descriptive study which took place over a period of 6 months in a hospital environment and in the general population. Results: Of the 1000 participants, 637 had hypertension, giving a prevalence of 63.70% with a female predominance. thirty-three percent (33%) were unaware of their high blood pressure. the age group 60 and more was the most represented (44%). A proportion of 33 and 23.20 were overweight and obese participants, respectively. Male subjects were more overweight than female, unlike obesity which was more common among female subjects. Sixty-two percent (62%) of hypertensives were treated, of whom 44% were non-compliant. the excessively high cost and consumption of medications as needed were the main factors in therapeutic non-compliance. twenty-two percent (22%) of all hypertensive patients and 35% of treated hypertensive patients were controlled. Women were more treated but less observant and less controlled than men. therapeutic coverage and combination therapy rates were lower in rural areas. Hypertensives who had a high level of education were better treated and controlled than those who had no level. Conclusion: High blood pressure remains a real public health problem in Mali. It is more common in people aged 60 and over and in females. One in three hypertensives were unaware of their hypertension. the majority received antihypertensive treatments, but only a minority of them had their hypertension controlled.

关键词： High Blood Pressure Screening Control Rate Mali

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Anal Pathologies: What Management at the Reference Health Center of Bamako’s Commune V?

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Open Journal of Gastroenterology 2024年第3期14卷 87-92页

作者： Sanra Déborah Sanogo Moussa Y. Dicko Ousmane Diarra Abou A. Diarra Drissa Katilé Abdoulaye Maiga Ouatou Mallé Sabine Drabo Makan S. tounkara Hourouma Sow Kadiatou doumbia Anselme Konaté Moussa t. Diarra Hepato-Gastroenterology Department CHU Point G Bamako Mali Service d’hépato-gastroentérologie CHU Gabriel Touré Bamako Mali Hepato-Gastroenterology Unit CSREF Commune V Bamako Mali

Anal pathologies are conditions affecting the anal margin and the anal canal. the aim of our study was to update data on anal diseases. Non-specific, it can reveal an emergency, a serious illness, a chronic disease or a benign condition. It was a prospective, descriptive and analytical study from April 2022 to March 2023, carried out in the hepato-gastroenterology unit of the Centre de Santé de Référence de la commune V du District de Bamako in Mali. Out of seven hundred and forty-nine (749) patients seen in consultation, 98 had anal pathology, i.e. a prevalence of 13.08%. the mean age was 40 ± 15.15 years and the sex ratio was 1.5. Hemorrhoidal disease and anal fissure were the most frequent pathologies in 66.4% and 24.4% of cases respectively. Medical treatment was initiated in 91.9% of patients with hemorrhoidal disease and 91.7% with anal fissure. Anal pathologies are common in young male patients. In our context, they are dominated by benign conditions.

关键词： Anal Pathologies Hemorrhoidal Disease Anal Fissure

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Chronic Hepatitis B Virus Infection: Biological Parameters in Patients treated with tenofovir Disoproxil Fumarate

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Open Journal of Gastroenterology 2024年第4期14卷 145-151页

作者： Sanra Déborah Sanogo Moussa Y. Dicko Lamine N’Diaye Ousmane Diarra Drissa Katilé Abdoulaye Maiga Ouatou Mallé Sabine Drabo Makan S. tounkara Hourouma Sow Kadiatou doumbia Anselme Konaté Moussa t. Diarra Hepato-Gastroenterology Department Centre Hospitalier Universitaire Du Point G Bamako Mali Hepato-Gastroenterology Department Gabriel Toure University Hospital Bamako Mali Hepato-Gastroenterology Unit Csref Commune V Bamako Mali

Chronic hepatitis B causes a liver disease characterized by inflammation of the liver parenchyma. the aim of this study was to investigate the evolution of biological parameters in patients treated with tenofovir for chronic B infection at the Commune V referral health center in Bamako. We obtained a prevalence of 14.15%. the most represented age group was 31 - 40 years, with 36.8%. the sex ratio was 1.44 in favour of men. Viral load was undetectable after 18 months of treatment in 25 patients (42.37%). tenofovir, the 1st-line drug in Mali, is effective on the biological parameters monitored in patients.

关键词： Viral Hepatitis B tenofovir Biological Parameters

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Acute Coronary Syndrome of Young Subjects at the Luxembourg Mother-Child University Hospital in Bamako

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World Journal of Cardiovascular Diseases（心血管病） 2024年第3期 157页

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Percutaneous Coronary Intervention in Acute Coronary Syndromes at the Mother-Child University Hospital Luxembourg in Bamako

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World Journal of Cardiovascular Diseases（心血管病） 2024年第4期 288页

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Screening, treatment and Control of High Blood Pressure on Five Sites in Mali

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World Journal of Cardiovascular Diseases（心血管病） 2024年第5期 322页

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Dyslipidemia in Adults with type 2 Diabetes in a Rural Community in Ganadougou, Mali: A Cross-Sectional Study

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Journal of Diabetes Mellitus 2024年第2期14卷 133-152页

作者： Abdoulaye Diawara Djibril Mamadou Coulibaly Drissa Kone Mama A. traore Drissa Konaté Dicko S. Bazi Oumar Kassogue Djeneba Sylla Fatoumata Gniné Fofana Oudou Diabaté Mariam traore Ibrahim Antoine Nieantao Kaly Keїta Mamadou Diarra Olivia Smith Jian Li Cheickna Cisse talib Yusuf Abbas Crystal Zheng Segun Fatumo Kassim traore Mamadou Wele Mahamadou Diakité Seydou O. doumbia Jeffrey G. Shaffer University of Sciences Techniques and Technologies of Bamako Bamako Mali National Federation of Community Health Associations Bamako Mali Department of tropical Medicine Medical Microbiology & Pharmacology John A. Burns School of Medicine University of Hawaii Manoa Honolulu USA Department Biostatistics and Data Science School of Public Health and Tropical Medicine Tulane University New Orleans USA Department of Biotechnology and Computer Science Burhani College Mazgaon Mumbai India School of Medicine Tulane University New Orleans USA Medical Research Council Uganda Virus Research Institute Entebbe Uganda London School of Hygiene and tropical Medicine London UK Departement of Biochemistry and Genetics Duquesne University College of Medicine Pittsburgh USA

Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. the disorder is common in type 2 diabetics (t2D) and is linked with t2D comorbidities, particularly cardiovascular disease. Dyslipidemia in t2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. there is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be captured through routine surveillance. this study aimed to characterize the prevalence and demo-graphic profile of dyslipidemia in t2D in the rural community of Ganadougou, Mali. We performed a cross-sectional study of 104 subjects with t2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and serological analyses. the overall prevalence of dyslipidemia in t2D patients was 87.5% (91/104), which did not differ by sex (P = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (P = .013 and.036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (P = .029 and .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. the high rates of dyslipidemia observed in Gandadougou, consistent with concomitant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for t2D patients in African rural settings.

关键词： Cholesterol Cross-Sectional Study Dyslipidemia Lipids Mali type 2 Diabetes

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Northeastern tropical Atlantic SSt and Sahel Rainfall Variability

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Atmospheric and Climate Sciences 2023年第4期13卷 431-454页

作者： Dahirou Wane Abdou Lahat Dieng coumba Niang Amadou t. Gaye Laboratoire de Physique de l’Atmosphère et de l’Océan Siméon Fongang Ecole Supérieure Polytechnique Université Cheikh Anta Diop de Dakar (LPAO-SF/ESP/UCAD) Dakar Senegal

the SSt variability during the summer period in the northeastern tropical Atlantic region (NtA) is characterized by an alternation of warming/cooling which represents 87% of the total variability. the aim of this paper is to study the atmospheric responses as well as the precipitation associated with these oceanic conditions. Based on Reynolds’s SSt from 1982 to 2019, a normalized Northern tropical Atlantic index (NtAI) is computed into the region between 15° - 25°W;12° - 16°N and a composite analysis is then performed. It is shown that the NtAI is significantly correlated with the SSt’s first principal component mode (PC1) in this region. Moreover, the composite of SSt anomalies and atmospheric parameters exhibits a strong local ocean-atmosphere interaction which highly impacts the large-scale atmospheric circulation in West Africa, particularly in the western Sahel. An in-depth analysis shows that the atmospheric response to the warm (cold) SSt is a cyclonic (anticyclonic) circulation in the lower layers near the West Africa Coast. this cyclonic (anticyclonic) circulation strengthens/reduces the moisture transport towards the continent in the low levels. In the middle layers of the atmosphere (500 hPa), the warm (cold) composite is associated with a decrease (increase) in the intensity of the African Easterly Jet (AEJ) whereas, in the upper atmosphere (200 hPa), the strengthening (weakening) of the tropical Easterly Jet (tEJ) is observed. With regard to the composite precipitation field, a positive/negative SSt anomaly is associated with significantly enhanced/reduced rainfall in the western Sahelian region. It is found that this relationship (correlation) increases as we are closer to the coasts.

关键词： SSt-Rain Sahel Rainfall Senegal Rainfall Ocean-Atmosphere Interaction

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