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Decision Making for Managing Community Flood Risks:Perspectives of United States Floodplain Managers

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International Journal of Disaster Risk Science 2021年第5期12卷 649-660页

作者： Jenna Tyler Abdul-Akeem Sadiq douglas S.noonan Rebecca M.Entress School of Public Administration University of Central FloridaOrlandoFL 32801USA O'Neill School of Public and Environmental Affairs Indiana University–Purdue University IndianapolisIN 46202USA

To reduce flood losses,floodplain managers make decisions on how to effectively manage their community’s flood *** there is a growing body of research that examines how individuals and households make decisions to manage their flood risks,far less attention has been directed at understanding the decision-making processes for flood management at the community *** study aimed to narrow this research gap by examining floodplain managers’perceptions of the quality of their community’s flood management decision-making *** gathered from interviews with 200 floodplain managers in the United States indicate that most floodplain managers perceive their community’s flood management decision-making processes to be *** results also indicate that communities participating in the Federal Emergency Management Agency’s Community Rating System,as well as communities with a higher level of concern for flooding and a lower poverty rate,are significantly more likely to report better flood management decision-making processes.

关键词： Community flood risk management Decision making Floodplain managers United States

Discussing the undiscussable : :a guide to overcoming defensive routines in the workplace / 1st ed.

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Discussing the undiscussable : :a guide to overcoming defens...

2007年

作者： noonan William R.

来源：畅想之星图书光盘版（南... 评论

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面包酵母菌在铅铜模拟废水中的吸附动力学

中国有色金属学报 2010年第4期20卷 788-794页

作者：代群威董发勤 M.J.noonan 张伟西南科技大学固体废物处理与资源化教育部重点实验室绵阳621010 西南科技大学环境与资源学院绵阳621010 林肯大学农业与生命科学系

探讨模拟重金属Pb2+-Cu2+混合废水中面包酵母菌的动力学吸附行为和各离子间的点位竞争吸附过程。选择面包酵母菌为吸附剂,分别对不同的Pb2+-Cu2+废水进行动力学吸附分析和二级动力学模型计算,同时,也进行SEM/EDS分析。结果表明:在最初60... 详细信息

探讨模拟重金属Pb2+-Cu2+混合废水中面包酵母菌的动力学吸附行为和各离子间的点位竞争吸附过程。选择面包酵母菌为吸附剂,分别对不同的Pb2+-Cu2+废水进行动力学吸附分析和二级动力学模型计算,同时,也进行SEM/EDS分析。结果表明:在最初60min时,酵母菌对Pb2+-Cu2+废水中离子已有较好的吸附效果,在整个动力学吸附过程中,酵母菌对废水中离子的吸附关系总是存在qt(Pb2+)>qt(Pb2+-Cu2+)>qt(Cu2+)。二级动力学方程计算结果显示:在Cu2+竞争胁迫环境下,增大Cu2+的比例使酵母菌对Pb2+的吸附速率更快,也证明Pb2+在吸附点位竞争过程中的明显优势,EDS测试结果也证实这点。SEM分析发现:酵母菌吸附Cu2+和Pb2+后,菌体出现不规则变形并遭受一定的破坏,有内部物质外泄现象。酵母菌对Cu2+和Pb2+都有一个快速吸附过程,相对而言其对Pb2+的吸附更具优势。

关键词：环境保护铅铜废水面包酵母菌生物吸附动力学

Novel approaches to therapeutics in pancreatic adenocarcinoma: vitamin C and tumor treatment fields

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Journal of Cancer Metastasis and Treatment 2021年第1期7卷 284-299页

作者： Laith Abushahin Travis Jones Jonathan Song Terence M.Williams Haseebah Shahzad Anne noonan Arthur G.James Comprehensive Cancer Center and Richard J.Solove Research Institute The Ohio State University Medical CenterColumbusOH 43210USA Department of Internal Medicine Division of Medical OncologyThe Ohio State UniversityColumbusOH 43210USA Department of Mechanical&Aerospace Engineering The Ohio State UniversityColumbusOH 43210USA Department of Radiation Oncology The Ohio State University Medical CenterColumbusOH 43210USA

Pancreatic ductal adenocarcinoma(PDAC)is a lethal disease with limited therapeutic *** extensive clinical research over the past several decades,meaningful improvements in care standards have been challenging to *** efforts are underway on several fronts,including cytotoxic chemotherapy combinations,immunotherapy,and targeted *** this review,we chose to focus less on mainstream avenues of clinical research in PDAC and highlight some novel and innovative research efforts that are typically outside the spotlight of *** of these novel approaches include pharmacologic vitamin C and electromagnetic *** review’s scope is to present the biological basis of the anti-cancer potential and the early clinical data,as well as the future landscape of these agents,including ongoing clinical trials in these therapeutic avenues.

关键词： Pancreas cancer vitamin C ascorbate tumor treatment fields induced electromagnetic field electromagnetic field therapy

Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma

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World Journal of Gastroenterology 2019年第28期25卷 3704-3721页

作者： Clifford Akateh Sylvester M Black Lanla Conteh Eric D Miller Anne noonan Eric Elliott Timothy M Pawlik Allan Tsung Jordan M Cloyd Department of Surgery The Ohio State University Wexner Medical Center Columbus OH 43210 United States Division of Transplant Surgery Department of Surgery The Ohio State University Wexner Medical Center Columbus OH 43210 United States Division of Gastroenterology Hepatology and Nutrition Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus OH 43210 United States Department of Radiation Oncology The Ohio State University Wexner Medical Center Columbus OH 43210 United States Division of Medical Oncology Department of Internal Medicine The Ohio State University Wexner Medical Center Columbus OH 43210 United States Division of Diagnostic Radiology Department of Radiology The Ohio State University Wexner Medical Center Columbus OH 43210 United States Division of Surgical Oncology Department of Surgery The Ohio State University Wexner Medical Center Columbus OH 43210 United States

Hepatocellular carcinoma (HCC) is the most common liver malignancy worldwide and a major cause of cancer-related mortality for which liver resection is an important curative-intent treatment option. However, many patients present with advanced disease and with underlying chronic liver disease and/or cirrhosis, limiting the proportion of patients who are surgical candidates. In addition, the development of recurrent or de novo cancers following surgical resection is common. These issues have led investigators to evaluate the benefit of neoadjuvant and adjuvant treatment strategies aimed at improving resectability rates and decreasing recurrence rates. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC. In this review, we evaluate the evidence for various neoadjuvant and adjuvant therapies and discuss opportunities for future clinical and translational research.

关键词： Hepatocellular carcinoma Neoadjuvant therapy Adjuvant therapy Neoplasm recurrence Hepatectomy Liver cirrhosis

Lateral Intra-Articular Transposition of the Anterior Tibialis Tendon for the Treatment of Relapsed Clubfoot in Toddlers: A Previously Unreported Surgical Technique

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Open Journal of Orthopedics 2014年第3期4卷 53-59页

作者： Dayton Opel Samuel Abrams Matthew Halanski Kenneth noonan Department of Orthopedics and Rehabilitation University of Wisconsin Madison USA University of Wisconsin School of Medicine and Public Health Madison USA

Dynamic supination of the foot is a common residual deformity in children with clubfeet treated with the Ponseti method. Transfer of the anterior tibialis tendon (ATT) to the lateral cuneiform is an effective method for correcting this deformity when the cuneiform is ossified in children who are 3 to 5 years of age. We describe two cases of a previously unreported method of ATT transposition for correction of bilateral residual dynamic supination in a 26-month-old and a 19-month-old patient. Both patients presented shortly after birth with bilateral congenital idiopathic clubfoot and were initially treated with the Ponseti method. Both had residual deformity following initial treatment that included posterior contracture and metatarsus adductus with dynamic forefoot supination. This was surgically corrected with a posterior release and medial release of the 1st metatarsal/1st cuneiform joint. To correct dynamic supination, the ATT was transplanted laterally into the released midfoot joint. These two patients were followed post-operatively for 7.5 years and have correction of their residual deformity in both feet based on subjective functioning, appearance, range of motion, strength, and gait. Both have excellent lateral pull of their ATT, which functions as a strong foot dorsiflexor. No residual supination is present. This is the first report of lateral transposition of the ATT as an interposition graft at the released 1st metatarsal/1st cuneiform joint in patients with relapsed clubfoot. We suggest that this method should provide a high level of functioning in children with relapsed supination deformity and whose 3rd cuneiform has not yet ossified.

关键词： Clubfoot Clubfoot Relapse Idiopathic Clubfoot Anterior Tibialis Tendon Transfer Ponseti Residual Foot Deformity Talipes Equinovarus

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一次性产品生产商面临的机遇和挑战

产业用纺织品 1998年第11期16卷 43-43,46页

作者： Ellen noonan Schutt 吴英

卫生用品是非织造布工业的最大市场之一,已被证明它最具有竞争力.提高主要生产企业的技术水平,不断竞争以及发展由小型企业生产的精致产品,可持续推进市场走向繁荣.非织造布卫生用品包括婴儿尿布和训练裤、成年人失禁用品和卫生防护用品... 详细信息

卫生用品是非织造布工业的最大市场之一,已被证明它最具有竞争力.提高主要生产企业的技术水平,不断竞争以及发展由小型企业生产的精致产品,可持续推进市场走向繁荣.非织造布卫生用品包括婴儿尿布和训练裤、成年人失禁用品和卫生防护用品,其中婴儿尿布用量最大.目前卫生用品市场在发达国家如美国、西欧和日本已趋于成熟,而在发展中国家和地区,

关键词：卫生用品非织造布一次性产品

Clinical Outcome Event Adjudication in a 10-Year Prospective Study of Nucleos(t)ide Analogue Therapy for Chronic Hepatitis B

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Journal of Clinical and Translational Hepatology 2020年第4期8卷 377-384页

作者： Joseph K Lim Alex Y Chang Atif Zaman Paul Martin Conrado M Fernandez-Rodriguez Mete Korkmaz Simona Rossi James M Ford Tamara noonan Elizabeth Cooney Victor Navarro Luis Colombato Yale University School of Medicine New HavenCTUSA Johns Hopkins School of Medicine BaltimoreMDUSA and Johns Hopkins SingaporeSingapore Oregon Health&Science University PortlandORUSA University of Miami Miller School of Medicine MiamiFLUSA Hospital Universitario Fundación Alcorcón MadridSpain OSF Saint Anthony Center for Cancer Care RockfordILUSA Einstein Healthcare Network PhiladelphiaPAUSA Stanford University School of Medicine StanfordCAUSA Bristol-Myers Squibb WallingfordCTUSA Hospital Británico UCA School of MedicineBuenos AiresArgentina

Background and Aims:In the REALM (Randomized, Obser-vational Study of Entecavir to Assess Long-Term Outcomes Associated with Nucleoside/Nucleotide Monotherapy for Pa-tients with Chronic HBV Infection) study, 12,378 patients with chronic hepatitis B virus (HBV) infection received up to 10 years of randomized therapy with entecavir or another HBV nucleos(t)ide analogue. Monitored clinical outcome events (COEs) included malignant neoplasms, HBV disease progres-sion events, and deaths. An external event adjudication com-mittee (EAC) was convened to provide real-time review of reported COEs to optimize data quality, and minimize poten-tial adverse effects of the large cohort, interdisciplinary out-come assessments, geographic scope, and long duration. Methods:The EAC comprised an international group of hep-atologists and oncologists with expertise in diagnosis of tar-geted COEs. The EAC reviewed and adjudicated COEs according to prospectively defined diagnostic criteria cap-tured in the EAC charter. Operational processes, including da-ta collection and query procedures, were implemented to optimize efficiency of data recovery to maximize capture of adjudicated COEs, the primary study outcome measure. Results: A total of 1724 COEs were reported and 1465 of these events were adjudicated by the EAC as reported by the investigators (85.0% overall concordance). Concordance by COE type varied: deaths, 99.6%;hepatocellular carcino-ma (HCC), 83.3%;non-HCC malignancies, 88.0%;non-HCC HBV disease progression, 68.2%. Reasons for lack of con-cordance were most commonly lack of adequate supporting data to support an adjudicated diagnosis or evidence that the event pre-dated the study. Conclusions: The REALM EAC performed a critical role in ensuring data quality and consis-tency;EAC performance was facilitated by well-defined diag-nostic criteria, effective data capture, and efficient operational processes. Trial registration: *** NCT00388674.

关键词： Hepatitis B Antiviral therapy Clinical outcomes Event adjudication Liver cirrhosis

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空中野餐

棒棒英语（中、英文对照） 2011年第3期 2-5页

作者： Diana noonan