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CCS Chemistry 2022年第1期4卷 1-5页

作者： Jiannian Yao Xi Zhang donna J.Minton Chinese Chemical Society 不详 CCS

Welcome to a New Year and the first issue of Volume 4 of CCS *** begin this new year having learned much and with a great deal to look forward to for CCS and CCS Chemistry!2022 is the 90th Anniversary of *** society h... 详细信息

关键词： China. begin learned

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FACTORS AFFECTING NATIVE JAPANESE SPEAKERS’ PRODUCTION OF INTRUSIVE （EPENTHETIC） VOWELS IN ENGLISH WORDS

FACTORS AFFECTING NATIVE JAPANESE SPEAKERS’ PRODUCTION OF I...

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6～(th) International Conference on Spoken Language Processing

作者： Keiichi Tajima donna Erickson Kyoko Nagao Information Sciences Division ATR International Kyoto Japan Gifu City Women’s College Gifu City Japan Konan University Kobe Japan

＜正＞ A salient characteristic of English spoken by native Japanese is th tendency to produce intrusive vowels between consonants or following word-final consonants （e.g., English "stress" as /***/）. This study conducted speech analysis of a large set of Japanese-accented English utterances to evaluate the effects of various factors on vowel epenthesis. Results reveal effects of speaking rate and phonetic environment, but little effect of word familiarity and frequency.

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Introductory mental health nursing

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2011年

作者： donna M. Womble

ISBN: (纸本)9781608313921

(Publisher-supplied data) Unit I Introduction to Mental Health and Mental Illness -- Mental Health and Mental Illness -- Theories of Personality Development -- Unit II Mental Health Care -- The Delivery of Mental Health Care -- Treatment of Mental Illness -- Psychopharmacology -- Unit III Fundamental Nursing Roles in Mental Health Care -- The Nursing Process in Mental Health Nursing -- Communicati

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Adapting to the Physical Changes of Aging with COPD

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Advances in Aging Research 2015年第4期4卷 120-132页

作者： Gail Low donna Wilson Michael Stickland Carolyn Ross Eric Wong Faculty of Nursing University of Alberta Edmonton Canada G. F. MacDonald Centre for Lung Health Covenant Health Edmonton Canada Division of Pulmonary Medicine University of Alberta Edmonton Canada

The prevalence of Chronic Obstructive Pulmonary Disease is growing, and people are living with this disease well into older age. Little is known about how people with Chronic Obstructive Pulmonary Disease adapt to aging, particularly the physical changes of aging. According to the Identity Process Theory, people are inclined to attribute age-related changes in physical functioning to a transitory state of health, but not their physical health or appearance. Attributing one’s physical functioning to aging itself makes people believe that they are physically “old” and enhances negative affect. We tested the Identity Process Theory using secondary physical functioning and physical health data collected from 87 pulmonary rehabilitation program participants with Chronic Obstructive Pulmonary Disease (age range = 47 - 82 years of age). Transient health states were participants’ 6-Minute Walk Distance and perceived breathlessness during a time-limited exercise test using the Borg Rating of Perceived Exertion Scale. Participants’ age-related changes in physical functioning were attributed to walk distances and their physical health to the physical changes of aging (X2 = 18.55, df = 10, p = 0.05;GFI = 0.95;RMSEA = 0.10). These attribution patterns were replicated in the Borg Rating of Perceived Exertion model (X2 = 13.34, df = 10, p = 0.21;GFI = 0.96;RMSEA = 0.06). The attributing of age-related changes in physical functioning to either transient health state circumvented their propensity for negative affect. Our findings are discussed in relation to maintaining physical functioning and general physical health promotion among Pulmonary Rehabilitation Program participants with Chronic Obstructive Pulmonary Disease.

关键词： Aging Physical Identity Pulmonary Rehabilitation COPD Mental Health

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善待自己第2卷

善待自己第2卷

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1999年

作者：（美）（D.沃森）donna Watson 赖志松译

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Magnetic resonance imaging-guided focused ultrasound to increase localized blood-spinal cord barrier permeability

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Neural Regeneration Research 2017年第12期12卷 2045-2049页

作者： Allison H.Payne Gregory W.Hawryluk Yoshimi Anzai Henrik Odéen Megan A.Ostlie Ethan C.Reichert Amanda J.Stump Satoshi Minoshima donna J.Cross Department of Radiology and Imaging Sciences University of Utah Salt Lake City UT USA Department of Neurosurgery University of Utah Salt Lake City UT USA

Spinal cord injury（SCI） affects thousands of people every year in the USA, and most patients are left with some permanent paralysis. Therapeutic options are limited and only modestly affect outcome. To address this issue, we used magnetic resonance imaging-guided focused ultrasound（MRg FUS） as a non-invasive approach to increase permeability in the blood-spinal cord barrier（BSCB）. We hypothesize that localized, controlled sonoporation of the BSCB by MRg FUS will aid delivery of therapeutics to the injury. Here, we report our preliminary findings for the ability of MRg FUS to increase BSCB permeability in the thoracic spinal cord of a normal rat model. First, an excised portion of normal rat spinal column was used to characterize the acoustic field and to estimate the insertion losses that could be expected in an MRg FUS blood spinal cord barrier opening. Then, in normal rats, MRg FUS was applied in combination with intravenously administered microbubbles to the spinal cord region. Permeability of the BSCB was indicated as signal enhancement by contrast administered prior to T1-weighted magnetic resonance imaging and verified by Evans blue dye. Neurological testing using the Basso, Beattie, and Breshnahan scale and the ladder walk was normal in 8 of 10 rats tested. Two rats showed minor impairment indicating need for further refinement of parameters. No gross tissue damage was evident by histology. In this study, we have opened successfully the blood spinal cord barrier in the thoracic region of the normal rat spine using magnetic resonance-guided focused ultrasound combined with microbubbles.

关键词： focused ultrasound spinal cord magnetic resonance imaging contrast-enhanced blood-spinalcord barrier

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CourseBuilder for Dreamweaver f/x & design

CourseBuilder for Dreamweaver f/x & design

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2001年

作者： donna L. Baker.

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Caveolae/caveolin-1/ERK_(1/2)信号通路在降钙素基因相关肽抑制血管平滑肌细胞增殖中的作用(英文)

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生物化学与生物物理进展 2013年第5期40卷 445-453页

作者：谌赟戴忠刘彦梅田海红邓水秀陈临溪 Wang H donna 秦旭平南华大学药物药理研究所动脉硬化学湖南省重点实验室衡阳421001 广东医学院药理教研室东莞523808 Deportment of Medicine Michigan State UniversityEast LansingMI 48824USA

业已证明,Caveolae及其蛋白caveolin-1参与了细胞膜的胆固醇转运和细胞膜的信号转导.我们前期工作发现降钙素基因相关肽(CGRP)抑制血管平滑肌细胞(VSMC)增殖的信号通路与抑制ERK1/2活性和上调caveolin-1表达有关.本文研究Caveolae及cave... 详细信息

业已证明,Caveolae及其蛋白caveolin-1参与了细胞膜的胆固醇转运和细胞膜的信号转导.我们前期工作发现降钙素基因相关肽(CGRP)抑制血管平滑肌细胞(VSMC)增殖的信号通路与抑制ERK1/2活性和上调caveolin-1表达有关.本文研究Caveolae及caveolin-1在CGRP抑制VSMC增殖中的作用,进一步研究caveolin-1表达增加是否有直接抑制ERK1/2信号激酶活性的作用.采用大鼠主动脉贴块法培养VSMC,取3～10代VSMC用于实验,10%小牛血清(FBS)用于刺激VSMC增殖,用β-环糊精(cyclodextrin)或菲律宾菌素(filipin)剥夺胆固醇破坏Caveolae结构;MTT法和流式细胞仪用于检测细胞增殖;蛋白质印迹和免疫共沉淀法分别用于检测目的蛋白的表达或蛋白质间相互作用.结果显示,CGRP呈时间和浓度依赖性显著抑制10%FBS诱导的VSMC增殖.细胞Caveolae结构的破坏能降低CGRP抑制VSMC增殖作用,同时也增加了ERK1/2的磷酸化;β-环糊精孵育细胞能降低caveolin-1的表达.免疫共沉淀发现10%FBS和/或CGRP共同孵育细胞对非磷酸化ERK1/2与caveolin-1的结合无差别,但10%FBS能降低磷酸化ERK1/2与caveolin-1的结合,CGRP预孵育细胞能增加这两者的相互作用.结果揭示,Caveolae及caveolin-1可以正调控CGRP抑制VSMC增殖作用,其机制可能与CGRP增加caveolin-1与p-ERK1/2在Caveolae的结合,并抑制p-ERK1/2核转位作用有关.

关键词： Caveolae caveolin-1 降钙素基因相关肽细胞外信号调节酶血管平滑肌细胞增殖

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Organizational commitment and turnover intention among rural nurses in the Philippines: Implications for nursing management

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International Journal of Nursing Sciences 2018年第4期5卷 403-408页

作者： Leodoro J.Labrague Denise M.McEnroe-Petitte Konstantinos Tsaras Jonas P.Cruz Paolo C.Colet donna S.Gloe Sultan Qaboos University MuscatOman Kent State University Tuscarawas USA Technological Educational Institute of Thessaly LarissaGreece Shaqra University Saudi Arabia Nazarbayev University Kazakhstan Southwest Baptist University USA

Objectives:The unrelenting migration trend of Filipino nurses to other countries has threatened the quality of patient care services in the *** study explored the extent of nurses'organizational commitment and turnover intention in the ***,predictors of nurses'organizational commitment and turnover intention were ***:A cross-sectional research design was adopted for this *** hundred nurses from nine rural hospitals in the Central Philippines were asked to participate in the study and 166 nurses responded(an 83%response rate).Two standardized instruments were used:the Organizational Commitment Questionnaire and the Six-item Turnover Intention Inventory ***:Findings revealed that Philippine nurses were moderately committed(3.13±0.24)to and were undecided(2.42±0.67)whether or not to leave their ***'age(P=0.006),gender,(t=-2.25,P=0.026),education(t=2.38,P<0.001),rank(t=4.38,P<0.001),and work experience(t=2.18,P=0.031)correlated significantly with organizational commitment,while nurses'age(P=0.028)and education(t=1.99,P=0.048)correlated significantly with turnover *** inverse relationship was identified between the organizational commitment and turnover intention(r=-0.22,P=0.005).Conclusion:The findings of this study highlight the need for formulation and implementation of interventions to promote life-long commitment in nurses and to reduce turnover rates.

关键词： Hospitals Rural Nurses Organizational commitment Philippines Turnover intention

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Spatial Community Ecology of Rainbow Smelt and Alewife in Lake Champlain, USA

Spatial Community Ecology of Rainbow Smelt and Alewife in La...

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2014年中国水产学会学术年会

作者： donna Parrish Paul Simonin Lars G.Rudstam Patrick J.Sullivan donna Parrish Bernard Pientka U.S.Geological Survey Vermont Cooperative Fish and Wildlife Research Unit Cornell University Cornell Biological Field Station Cornell University

Rainbow smelt（Osmerus mordax） and alewife（Alosa pseudoharengus） are pelagic fish species native to coastal regions of northeastern North America. Rainbow smelt are native to Lake Champlain, and alewife were first found in the lake in 2003. During the expansion of Lake Champlain’s alewife population, survival of age-0 rainbow smelt and alewife was studied in relation to adult abundance and habitat gradients in the aquatic environment. Spatial dynamics of these species are particularly important because both are cannibalistic, with cannibalism rate a function of spatial overlap and fish density. Using data collected over both diel and seasonal cycles, we determined what abiotic conditions influenced fish spatial distributions and created models predicting adult and age-0 rainbow smelt and alewife distribution. Distribution predictions were then coupled with previously-created predation models to simulate predation and cannibalism patterns. Our data show, and models predict, that alewife and rainbow smelt populations interact differently in different basins of the lake due to habitat availability, and under differing climatic and limnological scenarios. Our work also predicts, due to the importance of cannibalism, that neither species will extirpate the other.

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