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Neo-Confucian Theory of Mind as a Discourse of the Infinite： The Lu-Wang School

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Frontiers of Philosophy in China 2015年第1期10卷 75-94页

作者： zhao dongming Department of Philosophy College of Arts Shenzhen University Shenzhen 518060 China

This paper is a second-order study ofxinxue 心學（the Neo-Confucian theory of mind from the Lu-Wang school）. Having shown the difficulty of fitting the theory into philosophical or religious discourse, the paper will argue that it is more appropriate to see xinxue as a special variety of the ＂discourse of the infinite,＂ that is, discourse concerning the infinite, which will bring forth action. In this light, Lu Xiangshan 陸象山 and Wang Yangming＇s 王陽明 theory on the internal experience of the unity of mind is to be seen less as description of mental life than as an effort to adhere to the spirit of Mencius： they insist on the unity of the internal experience of mind, without allowing its intensity to be reduced in the explanatory theory of lixue 理學（theory of principles） espoused by Cheng Yi 程頤 and Zhu Xi 朱熹, and, in this way, strive to reaffirm Mencius＇s proclamation about the goodness of human nature. More importantly, the discourse as a whole works to enhance the status of the sage as someone who embodies tianli 天理（the highest moral principle of the universe）. This mode of discourse has the performative force of bringing forth moral actions. The real subject ofxinxue is not what Lu and Wang claim it to be, e.g. the essentially good human nature or the infinite moral mind. Rather, the subject of xinxue is that which reveals itself through a series of effortful discursive activities and in the moral practice thereby produced. The subject of xinxue that emerges from this continuous process of striving is a special subject even within the Confucian tradition, whose attention is directed mainly towards the internal experience of the unity of mind. This subject threatens to interrupt the intellectual as well as socio-political operations established by lixue, and therefore engenders a series of conflicts.

关键词： xinxue discourse of the infinite metaphysics irreducibility subject

Research on Autonomous Orbit Determination of Navigation Satellite Based on Crosslink Range and Orientation Parameters Constraining

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Geo-Spatial Information Science 2006年第1期9卷 18-23页

作者： CAI Zhiwu zhao dongming CHEN Jinping JIAO Wenhai Center of Information Application and Development Around World P. O. Box 5136 Beijing 100094 China

Autonomous navigation of navigation satellite is discussed. The method of auto-orbit determination using the erosslink range and orientation parameters constraining is put forward. On the basis of the analysis of its ... 详细信息

关键词： satellite navigations autonomous navigations orbit determination

Flexible Operation Mode of Coal-fired Power Unit Coupling with Heat Storage of Extracted Reheat Steam

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Journal of Thermal Science 2022年第2期31卷 436-447页

作者： WEI Haijiao LU Yuanwei YANG Yanchun ZHANG Cancan WU Yuting LI Weidong zhao dongming MOE Key Laboratory of Enhanced Heat Transfer and Energy Conservation Beijing Key Laboratory of Heat Transfer and Energy ConversionFaculty of Environment and LifeBeijing University of TechnologyBeijing 100124China China Huaneng Group Clean Energy Research Institute Co.Ltd Beijing 102209China

In order to provide more grid space for the renewable energy power,the traditional coal-fired power unit should be operated flexibility,especially achieved the deep peak shaving *** this paper,a new scheme using the reheat steam extraction is proposed to further reduce the load far below 50%rated *** flexible operation modes of increasing power output mode and reducing fuel mode are proposed in heat discharging process.A 600 MW coal-fired power unit with 50%rated power is chosen as the research *** results show that the power output is decreased from 300.03 MW to 210.07 MW when the extracted reheat steam flow rate is 270.70 t·h^(-1),which increases the deep peak shaving capacity by 15%rated *** deep peak shaving time and the thermal efficiency are 7.63 h·d^(-1)and 36.91%respectively for the increasing power output mode,and they are 7.24 h·d^(-1)and 36.58%respectively for the reducing fuel *** increasing power output mode has the advantages of higher deep peak shaving time and the thermal efficiency,which is recommended as the preferred scheme for the flexible operation of the coal-fired power unit.

关键词： coal-fired power unit flexible operation deep peak shaving extracted reheat steam heat storage

Modeling and Simulation of the Microstructure Evolution of the Gas-atomized Alloy Droplets during Spray Forming

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Journal of Materials Science & Technology 2003年第5期19卷 398-402页

作者： Jiuzhou zhao, dongming LIU and Hengqiang YEInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China Inst. of Metal Res. Chinese Acad. of Sci Shenyang 110016 China

In order to understand the solidification process of an atomized droplet and predict the fraction solidification of droplets with flight distance during spray forming, a numerical model based on the population dynamics approach is developed to describe the microstructure evolution under the common action of the nucleation and growth of grains. The model is coupled with droplets heat transfer controlling equations and solved for AI-4.5 wt pct Cu alloy. It is demonstrated that the numerical results describe the solidification process well.

关键词： Rapid solidification Microstructure evolution Modeling Spray forming

Glycosylation and an amino acid insertion in the head of hemagglutinin independently affect the antigenic properties of H5N1 avian influenza viruses

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Science China(Life Sciences) 2019年第1期62卷 76-83页

作者： Chunyang Gu Xianying Zeng Yangming Song Yanbing Li Liling Liu Yoshihiro Kawaoka dongming zhao Hualan Chen State Key Laboratory of Veterinary Biotechnology Harbin Veterinary Research Institute Chinese Academy of Agricultural Sciences Division of Virology Department of Microbiology and Immunology Institute of Medical Science University of Tokyo

Antigenic drift forces us to frequently update influenza vaccines; however, the genetic basis for antigenic variation remains largely unknown. In this study, we used clade 7.2 H5 viruses as models to explore the molecular determinants of influenza virus antigenic variation. We generated eight monoclonal antibodies(MAbs) targeted to the hemagglutinin(HA) protein of the index virus A/chicken/Shanxi/2/2006 and found that two representative antigenically drifted clade 7.2 viruses did not react with six of the eight MAbs. The E131 N mutation and insertion of leucine at position 134 in the HA protein of the antigenically drifted strains eliminated the reactivity of the virus with the MAbs. We also found that the amino acid N131 in the H5 HA protein is glycosylated. Our results provide experimental evidence that glycosylation and an amino acid insertion or deletion in HA influence antigenic variation.

关键词： Influenza virus H5N1 antigenic variation genetic basis

Sports Games Theory and Practice of Teaching in Physical Fitness

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International Journal of Technology Management 2015年第3期 56-58页

作者： dongming zhao Guizhou University of Finance and Economics Guiyang ER China 550025

The prevalence of physical fitness is for school to teach methods single-issue research, students try to find suitable ways and means of physical and mental exercise, play sports and fitness educational value of the original features. The traditional physical education is to become a vibrant so that life becomes boring exercises. The students＇ passive learning is for active participation, so that physical exercise achieves sterile body, sterile heart function, rich life, regulating mood, emotional exchange, harmonious sense of community for students to experience the joy of sports environment to promote the development of students＇ physical and mental health.

关键词： Game Education Fitness

A DNA length reducing computing model for maximum independent set problem

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Chinese Science Bulletin 2010年第24期55卷 892-898页

作者： Zhang Cheng Yang Jing Xu Jin zhao dongming Peking Univ Key Lab High Confidence Software Technol Sch Elect Engn & Comp Sci Inst SoftwareMinist Educ Beijing 100871 Peoples R China

In this paper, a new molecular computing model is developed to solve the maximum independent set problem, based on the method of DNA length reducing. To solve the maximum independent set problem with n-vertices and m-edges, the time complexity is O(n+m). With the enlargement of the problem scale, the numbers of the required tubes will increase linearly. Two important methods in this experiment are single strand DNA (ssDNA) circularization and DNA length reducing. In addition, using reverse polymerase chain reaction (PCR) and circligase, the structure of DNA molecules is changed in each computing step, transforming from linear double strand DNA (dsDNA) to linear ssDNA and circular ssDNA. Using the circular DNA structure, the recombina-tion among DNA molecules is avoided. To verify this computing model, a small maximum independent set problem was solved.

关键词： NP-complete problem reverse PCR linear ssDNA circularization DNA length reducing

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ASFV transcription reporter screening system identifies ailanthone as a broad antiviral compound

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Virologica Sinica 2023年第3期38卷 459-469页

作者： Yuhang Zhang Zhenjiang Zhang Fan Zhang Jiwen Zhang Jun Jiao Min Hou Nianchao Qian dongming zhao Xiaofeng Zheng Xu Tan College of Veterinary Medicine Hunan Agricultural UniversityChangsha 410128China State Key Laboratory of Veterinary Biotechnology Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150009China Beijing Advanced Innovation Center for Structural Biology Beijing Frontier Research Center for Biological StructureMOE Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical BiologySchool of Pharmaceutical SciencesTsinghua-Peking Center for Life SciencesTsinghua UniversityBeijing 100084China Institute of Health and Medicine Hefei Comprehensive National Science CenterHefei 230601 China

African swine fever(ASF)is an acute,highly contagious and deadly viral disease in swine that jeopardizes the worldwide pig ***,there are no authoritative vaccine and antiviral drug available for ASF *** swine fever virus(ASFV)is the etiological agent of *** the ASFV proteins,p72 is the most abundant component in the virions and thus a potential target for anti-ASFV drug ***,we con-structed a luciferase reporter system driven by the promoter of p72,which is transcribed by the co-transfected ASFV RNA polymerase *** this system,we screened over 3200 natural product compounds and obtained three potent candidates against *** further evaluated the anti-ASFV effects and proved that among the three candidates,ailanthone(AIL)inhibits the replication of ASFV at the nanomolar concentration(IC_(50)=15 nmol/L).Our in vitro experiments indicated that the antiviral effect of AIL is associated with its inhibition of the HSP90-p23 ***,we showed the antiviral activity of AIL on Zika virus and hepatitis B virus(HBV),which supports that AIL is a potential broad-spectrum antiviral agent.

关键词： African swine fever virus(ASFV) Replication inhibition Broad-spectrum antiviral drugs Ailanthone(AIL)

Establishment of an indirect immunofluorescence assay for the detection of African swine fever virus antibodies

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Journal of Integrative Agriculture 2024年第1期23卷 228-238页

作者： Wan Wang Zhenjiang Zhang Weldu Tesfagaber Jiwen Zhang Fang Li Encheng Sun Lijie Tang Zhigao Bu Yuanmao Zhu dongming zhao State Key Laboratory for Animal Disease Control and Prevention National African Swine Fever Para-reference LaboratoryNational High Containment Facilities for Animal Diseases Control and PreventionHarbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069China College of Veterinary Medicine Northeast Agricultural UniversityHarbin 150069China

African swine fever(ASF)continues to cause enormous economic loss to the global pig *** there is no safe and effective vaccine,accurate and timely diagnosis of ASF is essential to implement control *** immunofluorescence assay(IFA)is a gold standard serological method recommended by the World Organization for Animal Health(WOAH).In this study,we used primary fetal kidney cells to establish a wild boar cell line(BK2258)that supported the efficient replication of ASF virus(ASFV)SD/DY-I/21 and showed visible cytopathic effect(CPE).Moreover,using BK2258,we established a sensitive and specific IFA for ASFV antibody *** standardize and evaluate the performance of this assay,we used serum samples from pigs infected with the low virulent genotype I SD/DY-I/21 and genotype II HLJ/HRB1/20,and immunized with the vaccine candidate HLJ/18-7GD,field samples,and negative serum *** IFA reacted with the ASFV-positive sera and displayed bright fluorescence *** was no non-specific green fluorescence due to cellular senescence or other cell damage-causing *** to a commercial indirect enzyme-linked immunosorbent assay(iELISA),ASFV antibodies were detected 1–4 days earlier using our *** detection limits of the IFA and iELISA for the same ASFV-antibody positive serum samples were 1:25,600 and 1:6,400,respectively,indicating that the IFA is more sensitive than *** newly established IFA was highly specific and did not cross-react with sera positive for six other important porcine pathogens(i.e.,Classical swine fever virus(CSFV),Porcine reproductive and respiratory syndrome virus(PRRSV),Porcme circovirus type 2(PCV2),Pseudorabies virus(PRV),Foot-and-Mouth disease virus type O(FMDV/O),and Porcine epidemic diarrhea virus(PEDV)).This study thus provides a sensitive,specific,and reliable detection method that is suitable for the serological diagnosis of ASF.

关键词： African swine fever antibody IFA serological method