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A Three-Dimensional DEM Method for Trajectory Simulations of Rockfall under Irregular-Shaped Slope Surface and Rock Blocks

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Journal of Earth Science 2024年第1期35卷 306-312页

作者： Liang chen Weiqian Zeng Xianbiao Wang Yang Ye Yunfeng Ge dongming Gu Shan Dong Huadong Engineering Corporation Limited Fuzhou 350003China Faculty of Engineering China University of GeosciencesWuhan 430074China Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China

0 INTRODUCTION.Rockfall is a common geological hazard that poses a serious threat to residents and infrastructures(Gao et al.,2022;Ye et al.,2022).The precise prediction of rockfall trajectories is essential to the design of protection engineering structures of rockfall(Ma et al.,2021).The discrete element modelling(DEM)is increasingly used to analyse rockfall movement paths.Ma et al.(2022)used Rockyfor3D software to obtain the possible trajectory of falling rock blocks.

关键词： rock prediction hazard

A visual analysis approach for data imputation via multi-party tabular data correlation strategies

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Frontiers of Information Technology & Electronic Engineering 2024年第3期25卷 398-414页

作者： Haiyang ZHU dongming HAN Jiacheng PAN Yating WEI Yingchaojie FENG Luoxuan WENG Ketian MAO Yuankai XING Jianshu LV Qiucheng WAN Wei chen The State Key Lab of CAD&CG Zhejiang UniversityHangzhou 310058China Wuchan Zhongda Digital Technology Co. Ltd.Hangzhou 310020China Zhejiang Metals and Materials Co. Ltd.Hangzhou 310005China

Data imputation is an essential pre-processing task for data governance,aimed at filling in incomplete data.However,conventional data imputation methods can only partly alleviate data incompleteness using isolated tabular data,and they fail to achieve the best balance between accuracy and eficiency.In this paper,we present a novel visual analysis approach for data imputation.We develop a multi-party tabular data association strategy that uses intelligent algorithms to identify similar columns and establish column correlations across multiple tables.Then,we perform the initial imputation of incomplete data using correlated data entries from other tables.Additionally,we develop a visual analysis system to refine data imputation candidates.Our interactive system combines the multi-party data imputation approach with expert knowledge,allowing for a better understanding of the relational structure of the data.This significantly enhances the accuracy and eficiency of data imputation,thereby enhancing the quality of data governance and the intrinsic value of data assets.Experimental validation and user surveys demonstrate that this method supports users in verifying and judging the associated columns and similar rows using theirdomain knowledge.

关键词： Data governance Data incompleteness Data imputation Data visualization Interactive visual analysis

Pressure stimulated current in progressive failure process of combined coal-rock under uniaxial compression:Response and mechanism

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International Journal of Mining Science and Technology 2024年第2期34卷 227-243页

作者： Tiancheng Shan Zhonghui Li Xin Zhang Haishan Jia Xiaoran Wang Enyuan Wang Yue Niu Dong chen Weichen Sun dongming Wang State Key Laboratory of Coal Mine Disaster Prevention and Control China University of Mining and TechnologyXuzhou 221116China National Engineering Research Center for Coal Gas Control China University of Mining and TechnologyXuzhou 221116China School of Safety Engineering China University of Mining and TechnologyXuzhou 221116China State Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources China University of Mining and TechnologyXuzhou 221116China State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China

Effective monitoring of the structural health of combined coal-rock under complex geological conditions by pressure stimulated currents(PSCs)has great potential for the understanding of dynamic disasters in underground engineering.To reveal the effect of this way,the uniaxial compression experiments with PSC monitoring were conducted on three types of coal-rock combination samples with different strength combinations.The mechanism explanation of PSCs are investigated by resistivity test,atomic force microscopy(AFM)and computed tomography(CT)methods,and a PSC flow model based on progressive failure process is proposed.The influence of strength combinations on PSCs in the progressive failure process are emphasized.The results show the PSC responses between rock part,coal part and the two components are different,which are affected by multi-scale fracture characteristics and electrical properties.As the rock strength decreases,the progressive failure process changes obviously with the influence range of interface constraint effect decreasing,resulting in the different responses of PSC strength and direction in different parts to fracture behaviors.The PSC flow model is initially validated by the relationship between the accumulated charges of different parts.The results are expected to provide a new reference and method for mining design and roadway quality assessment.

关键词： Combined coal-rock Pressure stimulated current Progressive failure process Mechanism Flow model

Community Discovery Algorithm Based on Multi-Relationship Embedding

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Computer Systems Science & Engineering 2023年第9期46卷 2809-2820页

作者： dongming chen Mingshuo Nie Jie Wang Dongqi Wang Software College Northeastern UniversityShenyang110169China

Complex systems in the real world often can be modeled as network structures,and community discovery algorithms for complex networks enable researchers to understand the internal structure and implicit information of networks.Existing community discovery algorithms are usually designed for single-layer networks or single-interaction relationships and do not consider the attribute information of nodes.However,many real-world networks consist of multiple types of nodes and edges,and there may be rich semantic information on nodes and edges.The methods for single-layer networks cannot effectively tackle multi-layer information,multi-relationship information,and attribute information.This paper proposes a community discovery algorithm based on multi-relationship embedding.The proposed algorithm first models the nodes in the network to obtain the embedding matrix for each node relationship type and generates the node embedding matrix for each specific relationship type in the network by node encoder.The node embedding matrix is provided as input for aggregating the node embedding matrix of each specific relationship type using a Graph Convolutional Network(GCN)to obtain the final node embedding matrix.This strategy allows capturing of rich structural and attributes information in multi-relational networks.Experiments were conducted on different datasets with baselines,and the results show that the proposed algorithm obtains significant performance improvement in community discovery,node clustering,and similarity search tasks,and compared to the baseline with the best performance,the proposed algorithm achieves an average improvement of 3.1%on Macro-F1 and 4.7%on Micro-F1,which proves the effectiveness of the proposed algorithm.

关键词： Network representation learning multi-relationship node encoder attribute information

Upregulation of α-ENaC induces pancreatic β-cell dysfunction,ER stress,and SIRT2 degradation

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Journal of Biomedical Research 2024年第3期38卷 241-255页

作者： Xue Zhang Dan Zhang Lei Huo Xin Zhou Jia Zhang Min Li dongming Su Peng Sun Fang chen Xiubin Liang Department of Pathophysiology Nanjing Medical UniversityNanjingJiangsu 211166China Department of Pathology Nanjing Drum Tower Hospitalthe Affiliated Hospital of Nanjing University Medical SchoolNanjingJiangsu 210009China Key Laboratory of Human Functional Genomics of Jiangsu Province Department of Biochemistry and Molecular BiologyNanjing Medical UniversityNanjingJiangsu 211166China Department of Pathology Nanjing Medical UniversityNanjingJiangsu 211166China

Islet beta cells(β-cells)produce insulin in response to high blood glucose levels,which is essential for preserving glucose homeostasis.Voltage-gated ion channels inβ-cells,including Na+,K+,and Ca2+channels,aid in the release of insulin.The epithelial sodium channel alpha subunit(α-ENaC),a voltage-independent sodium ion channel,is also expressed in human pancreatic endocrine cells.However,there is no reported study on the function of ENaC in theβ-cells.In the current study,we found thatα-ENaC was expressed in human pancreatic glandule and pancreatic isletβ-cells.In the pancreas of db/db mice and high-fat diet-induced mice,and in mouse isletβ-cells(MIN6 cells)treated with palmitate,α-ENaC expression was increased.Whenα-ENaC was overexpressed in MIN6 cells,insulin content and glucose-induced insulin secretion were significantly reduced.On the other hand,palmitate injured isletβ-cells and suppressed insulin synthesis and secretion,but increasedα-ENaC expression in MIN6 cells.However,α-ENaC knockout(Scnn1a−/−)in MIN6 cells attenuatedβ-cell disorder induced by palmitate.Furthermore,α-ENaC regulated the ubiquitylation and degradation of sirtuin 2 inβ-cells.α-ENaC also modulatedβ-cell function in correlation with the inositol-requiring enzyme 1 alpha/X-box binding protein 1(IRE1α/XBP1)and protein kinase RNA-like endoplasmic reticulum kinase/C/EBP homologous protein(PERK/CHOP)endoplasmic reticulum stress pathways.These results suggest thatα-ENaC may play a novel role in insulin synthesis and secretion in theβ-cells,and the upregulation ofα-ENaC promotes isletβ-cell dysfunction.In conclusion,α-ENaC may be a key regulator involved in isletβ-cell damage and a potential therapeutic target for type 2 diabetes mellitus.

关键词： α-ENaC pancreaticβ-cells type 2 diabetes mellitus endoplasmic reticulum stress sirtuin 2

Multidimensional regulation of Ti-Zr-Cr-Mn hydrogen storage alloys via Y partial substitution

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Nano Research 2024年第5期17卷 4211-4220页

作者： Haixiang Xiu Wanqiang Liu dongming Yin Nan Ding Wenfeng Qiao Shaolei Zhao Long Liang Cong Liu Shaohua Wang Qingshuang Wang Bingbing chen Limin Wang Yong cheng School of Materials Science and Engineering Changchun University of Science and TechnologyChangchun 130022China State Key Laboratory of Rare Earth Resources Utilization Changchun Institute of Applied ChemistryChinese Academy of Sciences(CAS)Changchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Energy Science and Engineering Nanjing Tech UniversityNanjing 211816China National Engineering Research Center of Nonferrous Metals Materials and Products for New Energy GRINM Group Co.Ltd.Beijing 100088China GRIMAT Engineering Institute Co. Ltd.Beijing 101407China College of Life Science and Technology Changchun University of Science and TechnologyChangchun 130022China

High density and safe storage of hydrogen are the preconditions for the large-scale application of hydrogen energy.Herein,the hydrogen storage properties of Ti_(0.6)Zr_(0.4)Cr_(0.6)Mn_(1.4) alloys are systematically studied by introducing Y element instead of Ti element through vacuum arc melting.After the partial substitution of Y,a second phase of rare earth oxide is added in addition to the main suction hydrogen phase,C14 Laves phase.Thanks to the unique properties of rare earth elements,the partial substitution of Y can not only improve the activation properties and plateau pressure of the alloys,but also increase the effective hydrogen storage capacity of the alloys.The comprehensive properties of hydrogen storage alloys are improved by multidimensional regulation of rare earth elements.Among them,Ti_(0.552)Y_(0.048)Zr_(0.4)Cr_(0.6)Mn_(1.4) has the best comprehensive performance.The alloy can absorb hydrogen without activation at room temperature and 5 MPa,with a maximum hydrogen storage capacity of 1.98 wt.%.At the same time,it reduces the stability of the hydride and the enthalpy change value,making it easier to release hydrogen.Through theoretical analysis and first-principle simulation,the results show that the substitution of Y element reduces the migration energy barrier of hydrogen and the structural stability of the system,which is conducive to hydrogen evolution.The alloy has superior durability compared to the original alloy,and the capacity retention rate was 96.79%after 100 hydrogen absorption/desorption cycles.

关键词： AB_(2)-type hydrogen storage alloy rare earth element first-principles simulation multidimensional regulation

Nutritional and lipid profile status of children with spinal muscular atrophy in China: A retrospective case-control study

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中华医学杂志(英文版) 2024年第10期137卷 2024 Mar 21页

作者： Feng Yijie Wei Jia Yao Mei Jin Jianing Cui Yiqin Long Qi chen Fei Hong Yi Zhou dongming Hu Jingjing chen Xiao Gao Feng Yuan Changzheng Mao Shanshan Department of Neurology Children’s Hospital Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China Department of Infection Children’s Hospital Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China Department of Nutrition Children’s Hospital Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China Children’s Hospital Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China School of Public Health Zhejiang University School of Medicine Hangzhou Zhejiang China Children’s Hospital School of Public Health Zhejiang University School of Medicine National Clinical Research Center for Child Health Hangzhou Zhejiang China

Construction and Innovation of Comprehensive Evaluation Means of PBL+OBE-based Software Engineering Practical Courses

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计算机教育 2023年第12期 106-113页

作者： Yixian Liu Jun Guo dongming chen Software College Software Engineering National Experimental Teaching Demonstration CenterNortheastern UniversityShenyang110169China

Software engineering is an engineering discipline that guides software developers to carry out software development,software maintenance,and software management.The traditional evaluation methods of software engineering courses do not highlight the training goal of outcomebased education(OBE).This paper systematically studies the evaluation methods for practical courses in software engineering from three aspects:course evaluation guidelines,course evaluation methods and course evaluation effects;establishes a comprehensive,scientific,and objective system of course evaluation;effectively measures students’learning effect;promotes teachers to continuously improve the teaching process;and thus improves the teaching quality of software engineering courses.Besides the general approach,this paper also takes software project construction practice as an example to demonstrate the effect of the proposed approach.

关键词： Comprehensive evaluation PBL OBE Software engineering Practical coursess

Discussion on the Reform of Secure Coding

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计算机教育 2022年第12期 43-48页

作者： Yi Ma dongming chen Dongqi Wang software college Northeastern UniversityShenyang110006China

Secure Coding is an indispensable part of the undergraduate training program for Information Security Major.As a basic course for undergraduates to carry out project engineering,its importance is self-evident.In the actual teaching activities,the program design courses have to be solved in terms of content update,practical ability improvement and scientific research project,so the curriculum reform is imperative.This paper analyses the main problems existing in the Secure Coding course,explores the solution,proposes teaching methods,and gives the evaluation method.The practice shows that the reform exploration can obtain good teaching results.

关键词： Secure coding Case-based teaching method Modern teaching methods Evaluation methods