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Analysis of the Current Situation and Influencing Factors of Physical Activity Among the Elderly in the Community

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Journal of Clinical and Nursing Research 2024年第6期8卷 345-350页

作者： Wei Dong Jialiang Wang dongmei cui Yanling Li Shaohua Li Zheng Li Physical Examination Center Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Neurosurgery Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Nursing Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Neonatology Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina Department of Nephrology Affiliated Hospital of Hebei UniversityBaoding 071000Hebei ProvinceChina

Objective:To explore the current situation of physical activity among elderly individuals in the community,identify influencing factors,and provide a theoretical basis for improving their physical activity levels in the ***:A questionnaire survey was conducted among 265 elderly community residents using the Physical Activity Scale for the ***:The median(p50)score on the Physical Activity Scale for the Elderly was 220.425,indicating a high level of physical *** was no statistically significant difference in physical activity levels between ***:Elderly individuals should be supported in actively and scientifically participating in physical activities to mitigate physical function decline and achieve successful aging.

关键词： Community Elderly Physical activity

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跨文化交际视角下初中英语教学策略研究

英语教师 2024年第2期24卷 167-170页

作者：崔冬梅江苏省南通市如东县宾山初级中学江苏南通226000

分析跨文化交际视角下初中英语课堂教学现状,指明跨文化交际视角下初中英语课堂教学优化方向。结合译林版初中《英语》八年级(上)Unit 7 Seasons,探究跨文化交际视角下初中英语课堂教学的优化策略。认为教师应重塑课堂教学目标、组织课... 详细信息

分析跨文化交际视角下初中英语课堂教学现状,指明跨文化交际视角下初中英语课堂教学优化方向。结合译林版初中《英语》八年级(上)Unit 7 Seasons,探究跨文化交际视角下初中英语课堂教学的优化策略。认为教师应重塑课堂教学目标、组织课堂教学实践、完善教学评价模式。

关键词：立德树人初中英语课堂教学跨文化交际

基于TLR4/ERK通路探讨电针对功能性消化不良大鼠肠黏膜通透性的影响

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中医药导报 2024年第5期30卷 29-35页

作者：康朝霞崔冬梅贵州中医药大学贵州贵阳550025

目的:基于TLR4/ERK通路探讨电针对功能性消化不良(FD)大鼠肠黏膜通透性的影响。方法:选用50只SPF级8周龄SD雄性大鼠,按随机数字表法分为空白组(10只)、造模组(40只),造模组采用郭氏夹尾刺激法+不规则饮食法+冰生理盐水灌胃法的复合造模... 详细信息

目的:基于TLR4/ERK通路探讨电针对功能性消化不良(FD)大鼠肠黏膜通透性的影响。方法:选用50只SPF级8周龄SD雄性大鼠,按随机数字表法分为空白组(10只)、造模组(40只),造模组采用郭氏夹尾刺激法+不规则饮食法+冰生理盐水灌胃法的复合造模方法建立FD模型。选取造模成功的大鼠30只随机分为模型组、电针组、TAK242组,每组10只。电针组针刺“足三里“”太冲”穴后在足三里穴接电针仪干预,连续波,频率2 Hz,强度1 mA,每次干预30 min,1次/d,共14 d;TAK242组予以TLR4抑制剂TAK242(0.5 mg/kg)尾静脉注射,1次/d,共14 d。干预结束后比较各组大鼠胃内残留率、小肠推进率;ELISA检测血清中二胺氧化酶(DAO)浓度;生化检测方法检测脂多糖(LPS)、D-乳酸(D-LA)的浓度;免疫组化法检测MBP蛋白的表达;免疫印迹法检测TLR4、MyD88、MEK、ERK、p-MEK、p-ERK1/2蛋白的表达。结果:模型组大鼠胃内残留率较空白组明显上升(P0.05)。与空白组比较,模型组大鼠十二指肠组织MEK、ERK、p-MEK、p-ERK1/2蛋白相对表达量显著上调(P<0.01);电针组、TAK242组大鼠十二指肠组织MEK、ERK、p-MEK、p-ERK1/2蛋白相对表达量均较模型组降低(P<0.01);电针组MEK、ERK、p-MEK、p-ERK1/2蛋白相对表达量低于TAK242组(P<0.05)。模型组大鼠十二指肠组织MBP平均光密度值显著高于空白组(P<0.01),电针组、TAK242组大鼠十二指肠组织MBP平均光密度值较模型组明显下调(P<0.01),电针组十二指肠组织MBP平均光密度值低于TAK242组(P<0.05)。与空白组比较,模型组大鼠血清DAO、D-LA、LPS水平显著增高(P<0.01);电针组、TAK242组大鼠血清DAO、D-LA、LPS水平均降低(P<0.01);电针组大鼠血清DAO、D-LA、LPS水平低于TAK242组(P<0.05)。结论:电针可减轻FD大鼠十二指肠组织炎症反应,恢复肠黏膜屏障功能,其机制可能与下调TLR4-ERK通路相关蛋白表达有关。

关键词：功能性消化不良电针肠黏膜通透性 TLR4 大鼠

Coordination Polymerization of Renewable (E)-4,8-Dimethyl-1,3,7-Nonatriene by Rare-Earth Metal Catalysts

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Chinese Journal of Chemistry 2022年第16期40卷 1939-1944页

作者： Yang Jiang Zhen Zhang Shihui Li dongmei cui State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchunJilin130022 China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefeiAnhui230026 China Department of Materials Science and Engineering Jilin UniversityChangchunJilin 130022China

Coordination polymerization of renewable(E)-4,8-dimethyl-1,3,7-nonatriene(DMNT)has been performed using pyridyl-methylene-fluorenyl scandium complex 1,half-sandwich scandium complex 2,diiminophosphinato rare-earth metal complexes 3a—3c and 4a—4b,bis(phosphino)carbazolide yttrium complex 5 andβ-diketiminato yttrium complex *** scandium complexes 1 and 2,activated by[Ph3C][B(C6F5)4]and AliBu3,are moderately active and show perfect 1,2-regioselective(1,2>99%).Conversely,asymmetric diiminophophinato complexes 3a—3c promote the DMNT polymerization to produce high trans-1,4 regulated products with the activity trend:Sc

关键词： Biobased monomer Ligand effects Homogeneous catalysis Polymerization Elastomer

Self-assisted stereospecific polymerization of unmasked polar 4-methylthio-1-butene

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Science China Chemistry 2019年第6期62卷 761-766页

作者： Yunjie Chai Chunji Wu Dongtao Liu Mingtao Run dongmei cui College of Chemistry and Environmental Science Hebei University State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences

Stereospecific polymerization of polar olefins has always been an attractive but challenging project because the Lewis basic polar groups of monomers are usually poisonous to the Lewis acidic metal centers of the catalysts. In this contribution,thiophene-fused cyclopentadienyl scandium complexes 1-3 were successfully synthesized. Combined with alkylaluminium and organoborate, these complexes showed extremely low activity and no selectivity for 1-hexene polymerization. Surprisingly,highly stereo-selective coordination polymerization of unprotected polar 4-methylthio-1-butene has been achieved in high activity for the first time under the same polymerization conditions. High-molecular-weight(M_n=110×10~3) and perfectly syndiotactic(rrrr>99%) poly(4-methylthio-1-butene)(P(MTB)) was afforded. Thus the methylthio-group-assisted mechanism that the unmasked methylthio group promoted the polymerization through σ-π chelation to the active scandium center together with the vinyl group was proposed. Moreover, the methylsulfonyl functionalized syndiotactic poly(1-butene) was also easily prepared by the oxidation of P(MTB). These results provided a new route for the synthesis of functionalized stereo-regular polyolefins.

关键词： self-assisted polymerization stereoselectivity polar α-olefin rare-earth metal catalyst functionalized poly(1-butene)

A convenient method to prepare random LA/CL copolymers from poly(L-lactide) and ε-caprolactone

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Science China Chemistry 2018年第6期61卷 708-714页

作者： Hao Ouyang Kun Nie Dan Yuan Yong Zhang dongmei cui Yingming Yao Key Laboratory of Organic Synthesis of Jiangsu Province Suzhou Key Laboratory of Macromolecular Design and Precision Synthesisand State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials College of Chemistry Chemical Engineering and Materials Science Dushu Lake Campus Soochow University School of Chemistry and Chemical Engineering Taishan University State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences

Sequential addition of L-lactide(LA) followed by ε-caprolactone(CL), and simultaneous addition of both monomers, afforded random LA/CL copolymers in the presence of lanthanide aryloxides under mild conditions. Transesterification was proved to play a predominant role in random copolymer formation. Moreover, treatment of poly(L-lactide) with ε-CL led to random copolymer formation, which provides a new strategy not only to prepare random LA/CL copolymers, but also to directly modify PLLA.

关键词： random copolymers lanthanide complex transesterification lactide ε-caprolactone

Plasma Membrane Calcium ATPase Expression in Human Lens Epithelium Cell Lines

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Eye Science 2011年第1期26卷 35-43页

作者： Hui Yang dongmei cui Junwen Zeng Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou 510060 China

Purpose:To study the expression of four plasma membrane calcium ATPase (PMCA) isoforms in human lens epithelium cell lines (HLE-B3 cells) both on mRNA and protein ***:Both total mRNA and membrane protein samples were collected,after HLE-B3 cells were cultured to 90% *** Transcription Polymerase Chain Reaction (RT-PCR) were used to detect mRNAs of PMCA isoform 1,2,3,and 4 by using corresponding PMCA isoform 1,2,3,and 4 *** Blot analysis was employed to detect PMCA isoform 1,2,3,and 4 protein using corresponding anti-PMCA1,2,3,and 4 ***:A 420 bp fragment was amplified with PMCA1 primer.A 550 bp fragment was amplified with PMCA2 primer.A 840 bp fragment was amplified with PMCA4 *** fragment was amplified with PMCA3 *** Blotting confirmed that the expected ～153 kDa,～125 kDa and ～147 kDa protein were recognized by anti PMCA1,2 and 4 antibodies *** protein was recognized by PMCA3 ***:This is the first study showing only PMCA1,2,and 4 gene are expressed in HLE-B3 cells on both mRNA and protein ***3 is not expressed in HLE-B3 *** PMCA isoforms expression pattern in HLE-B3 cell lines is different from that in the lens of other ***2 may play a more important role over other isoforms.

关键词：钙ATP酶细胞系晶状体上皮逆转录聚合酶链反应 Western印迹蛋白水平 mRNA

血液透析期间香蕉摄入量对患者血清钾水平的影响:一项膳食管理的随机对照试验

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International Journal of Nursing Sciences 2024年第2期11卷 197-204页

作者：全梓林李彩霞赵立艳崔冬梅刘双信尹燕唐奇曾德汉宋利符霞 The Department of Nephrology The Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouChina The Department of Nursing The Eighth Affiliated HospitalSun Yat-Sen UniversityShenzhenChina

目的评估血液透析期间香蕉摄入量对维持性血液透析患者(maintenance hemodialysis,MHD)血清钾水平的影响。方法本研究为单中心、随机对照临床试验,于2021年9月15日至12月15日选取中国南方地区1所三级甲等医院的126例MHD患者,并将其随机... 详细信息

目的评估血液透析期间香蕉摄入量对维持性血液透析患者(maintenance hemodialysis,MHD)血清钾水平的影响。方法本研究为单中心、随机对照临床试验,于2021年9月15日至12月15日选取中国南方地区1所三级甲等医院的126例MHD患者,并将其随机分为干预组(n=64)和对照组(n=62)。干预组患者在血液透析期间摄入约250克香蕉,而对照组患者在血液透析期间不摄入任何食物。在血液透析前通过病例信息收集患者人口学信息和血液透析相关参数,通过采集患者透析前血液样品来评估实验室指标(如血常规、生化指标、炎症指标、肝功能、肾功能等)。在血液透析2 h和4 h、下次血液透析前分别测量两组患者的血清钾和血糖水平,并记录透析中相关并发症。采用重复测量方程分析对两组患者血清钾和血糖指标进行比较。结果最终122例MHD患者完成研究(干预组和对照组各61例)。结果显示,两组患者血清钾水平在组别和时间上不存在交互作用(P>0.05),而干预组患者血清钾水平在血液透析2 h(3.9±0.5比3.6±0.3)mmol/L和血液透析4 h(3.5±0.4比3.3±0.3)mmol/L均高于对照组(P0.05)。干预组患者在血液透析期间心律失常(8.2%比29.5%,P=0.003)和低钾血症的发生率(52.5%比80.3%,P=0.002)均低于对照组。结论血液透析开始时摄入约250 g香蕉不会引起高钾血症,可有效降低低钾血症和心律失常的发生率,并防止血液透析过程中血清钾水平下降过快。建议医务人员应与营养学家进一步合作,为MHD患者制订适用的膳食管理计划。

关键词：血糖水果血液透析护理钾血清

归脾汤联合琥珀酸亚铁片和输血治疗用于重度缺铁性贫血患者的疗效及对血常规指标、铁代谢和免疫功能的影响

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中国医院用药评价与分析 2024年第4期24卷 439-442页

作者：陈哲崔冬梅张灵袁小飞张斌高炳华河北北方学院附属第一医院血液科河北张家口075061 北京市平谷区医院血液科北京101200 河北北方学院附属第一医院检验科河北张家口075061

目的:探讨归脾汤联合琥珀酸亚铁片和输血治疗用于重度缺铁性贫血患者的疗效及对血常规指标、铁代谢和免疫功能的影响。方法:选取2018年1月至2023年5月于河北北方学院附属第一医院就诊的重度缺铁性贫血患者130例,以信封抽签法随机分为观... 详细信息

目的:探讨归脾汤联合琥珀酸亚铁片和输血治疗用于重度缺铁性贫血患者的疗效及对血常规指标、铁代谢和免疫功能的影响。方法:选取2018年1月至2023年5月于河北北方学院附属第一医院就诊的重度缺铁性贫血患者130例,以信封抽签法随机分为观察组(65例)和对照组(65例)。两组患者均给予输血治疗,对照组患者口服琥珀酸亚铁片,观察组患者口服琥珀酸亚铁片和归脾汤。治疗4周后,对临床疗效进行评价,观察治疗前后两组患者的血常规指标[血红蛋白(Hb)、红细胞计数(RBC)、平均红细胞血红蛋白量(MCH)和平均红细胞体积(MCV)]、铁代谢指标[血清铁(SI)、血清铁蛋白(SF)和可溶性转铁蛋白受体(sTfR)]及免疫功能指标(CD3^(+)、CD4^(+)和CD8^(+)T淋巴细胞比例)水平,并记录不良反应。结果:与对照组[86.15%(56/65)]比较,观察组患者的总有效率[96.92%(63/65)]更高,差异有统计学意义(P0.05)。结论:归脾汤联合琥珀酸亚铁片和输血治疗用于重度缺铁性贫血患者的疗效较好,可改善血常规指标、铁代谢情况及免疫功能,且安全性好。

关键词：归脾汤琥珀酸亚铁片输血治疗重度缺铁性贫血