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Management Performance Evaluation Model of Korean Construction Firms

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Journal of Building Construction and Planning Research 2013年第2期1卷 27-38页

作者： donghoon lee Manki Kim Sunkuk Kim Department of Architectural Engineering Kyung Hee University Seoul Republic of Korea

Corporate management performance evaluation currently focuses on financial aspects;however, it is necessary to identify and manage elements that contribute to increased economic values in the long run. When it comes to construction firms, most previous research did not cover weighting and estimation approaches for non-financial elements that ultimately influence financial status. In this research, the objective is to develop a management performance evaluation model for Korean construction firms. The model includes financial factors and non-financial factors. This research investigated actual data from Korean construction firmsandclassifiedtheir characteristics. This study is performed in two steps. First, this study derives KPIs for performance measurement techniques and weights the KPIs. And then, it applies the performance data of construction firms to the technique. The findings of this study show that Korean construction firms consider customers to be the foremost priority, converse to previous research which argued that the internal business process was the top priority. The performance measurement results can be fed back into strategies and plans to shed light on issues, reflect on management plans for subsequent years and modify mid to long-term strategies. Therefore, the developed model can help decision-makers effectively revise their management plans.

关键词： Management Performance Evaluation Key Performance Indicators Balanced Scorecard AHP Fuzzy

Magnetic resonance imaging biomarkers for pulsed focused ultrasound treatment of pancreatic ductal adenocarcinoma

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World Journal of Gastroenterology 2020年第9期26卷 904-917页

作者： Ezekiel Maloney Yak-Nam Wang Ravneet Vohra Helena Son Stella Whang Tatiana Khokhlova Joshua Park Kayla Gravelle Stephanie Totten Joo Ha Hwang donghoon lee Department of Radiology University of WashingtonSeattleWA 98195United States Applied Physics Laboratory University of WashingtonSeattleWA 98195United States Division of Gastroenterology University of WashingtonSeattle 98195WAUnited States Division of Gastroenterology&Hepatology Stanford University School of MedicineRedwood CityCA 94063United States

BACKGROUND The robust fibroinflammatory stroma characteristic of pancreatic ductal adenocarcinoma(PDA)impedes effective drug *** focused ultrasound(pFUS)can disrupt this stroma and has improved survival in an early clinical ***-invasive methods to characterize pFUS treatment effects are desirable for advancement of this promising treatment modality in larger clinical *** To identify promising,non-invasive pre-clinical imaging methods to characterize acute pFUS treatment effects for in vivo models of *** We utilized quantitative magnetic resonance imaging methods at 14 tesla in three mouse models of PDA(subcutaneous,orthotopic and transgenic-KrasLSLG12D/+,Trp53LSL-R172H/+,Cre or“KPC”)to assess immediate tumor response to pFUS treatment(VIFU 2000 Alpinion Medical Systems;475 W peak electric power,1 ms pulse duration,1 Hz,duty cycle 0.1%)vs sham therapy,and correlated our results with histochemical *** pFUS treatment parameters were previously shown to enhance tumor permeability to chemotherapeutics.T1 and T2 relaxation maps,high(126,180,234,340,549)vs low(7,47,81)b-value apparent diffusion coefficient(ADC)maps,magnetization transfer ratio(MTR)maps,and chemical exchange saturation transfer(CEST)maps for the amide proton spectrum(3.5 parts per million or“ppm”)and the glycosaminoglycan spectrum(0.5-1.5 ppm)were generated and analyzed pre-treatment,and immediately post-treatment,using *** were sacrificed immediately following post-treatment *** whole-tumor was selected as the region of interest for data analysis and subsequent statistical analysis.T-tests and Pearson correlation were used for statistical *** Mean high-b value ADC measurements increased significantly with pFUS treatment for all *** glycosaminoglycan CEST and T2 measurements decreased significantly post-treatment for the KPC *** MTR and amide CEST values increased significantly for the KPC *** acid focal int

关键词： Pancreatic adenocarcinoma Multiparametric magnetic resonance imaging Focused ultrasound

Enhancement of Power Generation in Microbial Fuel Cells through Supplementation of <i>Platycodon grandiflorum</i>in Doraji Roots

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Journal of Sustainable Bioenergy Systems 2019年第4期9卷 169-178页

作者： Jung-In Park Hyunjin Kim Dae Kyung Go Peter S. Park Sang Heon lee Min Jung Koh Jonathan Jo donghoon lee Seungshin lee Paul S. Chung Fuzbien Technology Institute Rockville MD USA Youth with Talents Fairfax VA USA St. Johnsbuury Academy Jeju Korea Department of Biology School of Arts and Sciences Cornell University Ithaca NY USA School of Arts and Sciences Johns Hopkins Baltimore MD USA

The current study reports the evidence of enhancement in power generation from cellulosic biomass in microbial fuel cell (MFC) systems by supplementing dried Doraji (Platycodon grandiflorum) roots powder. Mediator-less two chamber H-type MFCs were prepared using rumen fluid as anode inocula to convert finely ground pine tree (Avicel) at 2% (w/v) to electricity. Dried Doraji roots were ground to pass 1 mm sieve and added to the anode of MFC at 0.1% w/v dosage for treatment. MFC power and current across an external resistor were measured daily for 10 d. At the end of incubation on d10, collected gases were measured for total gas volume and analyzed for gas composition on gas chromatography. Supplementation of Doraji roots powder to MFC anode chamber increased power generation and CO2 production. Over the 10d experimental period, power density normalized to anode surface area were between 17.0 and 37.7 with average of 32.5 mW/m2 in Doraji MFCs, and between 16.8 and 19.8 with average of 18.2 mW/m2 in control group. CO2 production increased and methane to CO2 ratio decreased in Doraji root treatment comparing to control group. These observations imply that Doraji root components would inhibit methanogenesis and alter microbial fermentation of cellulose compounds favorable to produce bioenergy efficiently in MFC.

关键词： MFC Platycodon grandiflorum

Patterns of Pediatric Malaria Incidence and Outcomes in Kasungu, Malawi in 2016

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Advances in Infectious Diseases 2019年第4期9卷 277-284页

作者： Byungchan Kim Sohyun Chang Min Jae Shin Prescott Hong George lee Min Jung Koh Immanuel H. Anaborne donghoon lee Paul S. Chung George Talama Thomas Nyirenda Department of Radiology Washington University St. Louis MO USA Department of Art & Science Biology Johns Hopkins University Baltimore MD USA Youth with Talents Fairfax VA USA Kasungu District Hospital Kasungu District Malawi Clinical Research Education and Management Service Lilongwe Malawi

Malawi is resource poor country in Africa with one of the highest infant and child mortality rates in the world. Malaria is one of the major causes of morbidity and mortality among children in Malawi. Studies have shown barriers to care of sick children and the formal health sector has shown sub-optimal patient assessments and overreliance on antibiotic treatment of a child with fever. In 2017, a team of students from Korea and USA audited clinic registers of six health centres under the hospital’s administration of Kasungu District in Malawi for the year of 2016. The clinics were included in the study were those that contributed to the largest number of patients in the district annually. The aim of the audit was to examine treatment outcomes of all children presenting with fever and on whom a definitive diagnosis or presumptive diagnosis of malaria was made at the 6 chosen clinics in Kasungu for improvement of health information system for the district health office. The number of children with malaria ranged between 80 and 440 per month, with the peak occurring between the rainy months of February to May. Peak mortality rate occurred in September and November at 21%. Patients presented with multiple symptoms of fever, convulsion, pallor, vomiting, cough, diarrhea, abdominal pain and headache. Average mortality rate differed between traditional authorities, ranging from 4% to 15%. Off-season high mortality finding promotes more studies looking into socioeconomic and hospital support. Multiple symptoms among patients treated for malaria is a common finding emphasizing the need to integrate household practices for malaria prevention, good malaria case management and linkage with community care of childhood illness (CCM) programs at the clinics in the district.

关键词： Case Management Childhood Fever Kasungu Malawi Mortality Pediatric Malaria

Pressure distribution inside oscillating heat pipe charged with aqueous Al_2O_3 nanoparticles,MWCNTs and their hybrid

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Journal of Central South University 2014年第6期21卷 2341-2348页

作者： Md.Riyad Tanshen Sinil lee Junhyo Kim donghoon Kang Jungpil Noh HanShik Chung HyoMin Jeong Sunchul Huh Department of Energy and Mechanical Engineering Gyeongsang National UniversityCheondaegukchi-Gil 38TongyeongGyeongnam 650-160Korea Department of Marine Engineering Mokpo National Maritime UniversityHaeyangdaehak-ro 91Mokpo-siJeollanam-do 530-729Korea Department of Naval Architecture and Ocean Engineering Gyeongsang National UniversityInstitute of Marine IndustryCheondaegukchi-Gil 38TongyeongGyeongnam 650-160Korea Department of Energy and Mechanical Engineering Gyeongsang National UniversityInstitute of Marine IndustryCheondaegukchi-Gil 38TongyeongGyeongnam 650-160Korea

Effective thermal performance of oscillating heat pipe(OHP)is driven by inside pressure *** transfer phenomena were reported in terms of pressure and frequency of pressure fluctuation in multi loop OHP charged with aqueous Al2O3 and MWCNTs/Al2O3 *** influences on thermal resistance of aqueous Al2O3,MWCNTs as well as the hybrid of them in OHP having 3 mm in inner diameter were investigated at 60% filling *** results show that thermal characteristics are significantly inter-related with pressure distribution and strongly depend upon the number of pressure fluctuations with *** of pressure depends upon the power input in evaporative section.A little inclusion of MWCNTs into aqueous Al2O3 at 60% filling ratio achieves the highest fluctuation frequency and the lowest thermal resistance at any evaporator power input though different nanofluids cause different thermal performances of OHPs.

关键词： oscillating heat pipe pressure fluctuation thermal resistance nanofluids

Characterization of CD8＋CD57＋ T cells in patients wit acute myocardial infarction

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Cellular & Molecular Immunology 2015年第4期12卷 466-473页

作者： Hee Tae Yu Jong-Chan Youn Jino lee Seunghyun Park Ho-Seok Chi Jungsul lee Chulhee Choi Sungha Park donghoon Choi Jong-Won Ha Eui-Cheol Shin Laboratory of Immunology and Infectious Diseases Graduate School of Medical Science and Engineering KAIST Daejeon Republic of Korea Cardiology Division Severance Cardiovascular Hospital Yonsei University College of Medicine Seoul Republic of Korea Department of Bio and Brain Engineering KAIST Daejeon Republic of Korea ' ' The first two authors contributed equally to this article

Although T cells are known to be involved in the pathogenesis of coronary artery disease, it is unclear which subpopulation of T cells contributes to pathogenesis in acute myocardial infarction （MI）. We studied the immunological characteristics and clinical impact of CD8＋CD57＋ T cells in acute MI patients. The frequency of CD57＋ cells among CD8＋ T cells was examined in peripheral blood sampled the morning after acute MI events. Interestingly, the frequency of CD57＋ cells in the CD8＋ T-cell population correlated with cardiovascular mortality 6 months after acute MI. The immunological characteristics of CD8＋CD57＋ T cells were elucidated by surface immunophenotyping, intracellular cytokine staining and flow cytometry. Immunophenotyping revealed that the CD8＋CD57＋ T cells were activated, senescent T cells with pro-inflammatory and tissue homing properties. Because a high frequency of CD8＋CD57＋ T cells is associated with short-term cardiovascular mortality in acute MI patients, this specific subset of CD8＋ T cells might contribute to acute coronary events via their pro-inflammatory and high cytotoxic capacities. Identification of a pathogenic CD8＋ T-cell subset expressing CD57 may offer opportunities for the evaluation and management of acute MI.

关键词： acute myocardial infarction CD8+CD57+ T cells immunosenescence

Efficacy and safety of rebamipide/nizatidine in patients with erosive gastritis: A randomized, multicenter, phase 4 study

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World Journal of Gastroenterology 2024年第48期30卷 5152-5161页

作者： donghoon Kang Myung-Gyu Choi Ki-Nam Shim Hye-Kyung Jung Seung-Joo Nam Jung Ho Park Sang Gyun Kim Nam-Hoon Kim Su Jin Hong Tae Joo Jeon Jae Il Chung Hang Lak lee Ju Yup lee Tae Oh Kim Chang Min lee Sun Moon Kim Jeong-Hwan Kim Jang Eon Kim Jeong Seop Moon Ho Dong Kim Wan-Sik lee Hong Jun Park Department of Internal Medicine Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 06591South Korea Department of Internal Medicine Ewha Womans University Seoul HospitalGastroenterology and Hepatology CenterSeoul 07985South Korea Department of Internal Medicine Ewha Womans University Mokdong HospitalSeoul 07985South Korea Department of Internal Medicine Kangwon National University School of MedicineChuncheon 24289South Korea Department of Medicine Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoul 03181South Korea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul 03080South Korea Department of Internal Medicine Ilsan Paik HospitalInje University College of MedicineGoyang 10380South Korea Department of Internal Medicine Digestive Disease CenterSoonchunhyang University Bucheon HospitalBucheon 31538South Korea Department of Internal Medicine Inje University College of MedicineSanggye Paik HospitalSeoul 01757South Korea Department of Gastroenterology Sahmyook Medical CenterSeoul 02500South Korea Department of Internal Medicine Hanyang University College of MedicineSeoul 04763South Korea Department of Internal Medicine Keimyung University School of MedicineDaegu 42601South Korea Department of Internal Medicine Inje University Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Department of Internal Medicine Gyeongsang National University School of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Internal Medicine Konyang University HospitalDaejeon 35365South Korea Gastroenterology Center Konkuk University Medical CenterSeoul 05030South Korea Department of Gastroenterology Seoul Medical CenterSeoul 02053South Korea Department of Gastroenterology Inje University Busan Paik HospitalBusan 47392South Korea Department of Gastroenterology St.Carollo HospitalSooncheon 57931South Korea Division of Gastroenterology Department of Internal

BACKGROUND For the treatment of gastritis,rebamipide,a mucoprotective agent,and nizatidine,a gastric acid suppressant,are commonly employed *** To compare the efficacy of Mucotra®SR(rebamipide 150 mg)and Axid®(nizatidine 150 mg)combination therapy with the sole administration of Axid®in managing erosive *** A total of 260 patients diagnosed with endoscopically confirmed erosive gastritis were enrolled in this open-label,multicenter,randomized,phase 4 clinical trial,allocating them into two groups:Rebamipide/nizatidine combination twice daily vs nizatidine twice daily for 2 *** full-analysis set analysis encompassed 239 patients(rebamipide/nizatidine,n=121;nizatidine,n=118),while the per-protocol analysis included 218 patients(n=110 vs 108).Post-treatment assessments comprised primary(erosion improvement rate)and secondary(erosion and edema cure rates,erythema improvement rates,hemorrhage,and gastrointestinal symptoms)***,drug-related adverse effects were *** Primary efficacy assessment showed a statistically significant improvement rate in mucosal erosions in the combination group compared to the control group in the full-analysis set(rebamipide/nizatidine 62.0%,nizatidine 49.2%,P=0.046),with a similar trend noted in the per-protocol analysis(62.7%vs 50.0%,P=0.058).Both groups were effective in curing erosion and edema and improvement of bleeding,erythema,and gastrointestinal symptoms,whereas no inter-group differences were *** confined to the participants with gastritis symptoms,improvement of erosion was more optimal in the combination group(63.0%vs 49.5%,P=0.046).No adverse events related to the drugs were *** Rebamipide/nizatidine combination is effective in treatment of erosive gastritis.

关键词： Gastritis Erosive gastritis Combination therapy Rebamipide Nizatidine