检索结果-南通市图书馆

Effect of CT-Guided Microwave Ablation Combined with TACE on Liver Function and Survival of Patients with Primary Liver Cancer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第1期8卷 119-124页

作者： Bo Chen donghong shi Min Ai Longjiang Zhang Department of Medical Imaging Eastern Theater Command General HospitalNanjing 210002Jiangsu ProvinceChina

Objective:To explore the effect of transarterial chemoembolization(TACE)+CT-guided microwave ablation(MWA)on treating patients with primary liver ***:78 primary liver cancer cases were enrolled and divided into groups according to their assigned surgical *** control group was treated with TACE alone,and the observation group was treated with TACE+CT-guided *** efficacy of the treatment and the liver function indicators and follow-up results of the patients of the two groups were ***:The efficacy of the treatment received by the observation group was higher than that of the control ***,the patients in the observation group exhibited better improvement in liver function indicators after 3 months of ***,the survival rates of 1 and 2 years after surgery of the observation group were all higher than those of the control group(P<0.05).Conclusion:TACE combined with CT-guided MWA is more effective in treating primary liver cancer compared to TACE ***,it resulted in better improvement of liver function and long-term survival ***,this treatment regime should be popularized.

关键词： CT guidance Microwave ablation TACE Primary liver cancer Liver function Survival status

Arterial Embolization: A Superior Treatment for Massive Urinary Tract Bleeding in Emergency Care

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proceedings of Anticancer Research 2024年第2期8卷 88-93页

作者： Bo Chen donghong shi Min Ai Longjiang Zhang Department of Medical Imaging General Hospital of the Eastern Theater Command of the Chinese People’s Liberation ArmyNanjing 210002China

Objective:To analyze the effect of arterial embolism(AE)in patients with massive urinary system bleeding(MBUS).Methods:From September 2018 to September 2023,175 cases of MBUS patients in the emergency department of the hospital were randomly selected and divided into groups according to the length of *** them,85 cases(September 2018–September 2020)underwent bladder irrigation treatment with aluminum potassium sulfate solution through a catheter(Group A),and 90 cases(October 2020–September 2023)underwent AE treatment(Group B).The treatment effects of the two groups were ***:The treatment effectiveness of Group B is higher than that of Group A(P<0.05).The urinary hemoglobin level of Group B is lower than that of Group A at 1,6,12,and 24 hours after treatment(P<0.05).Among the 90 cases treated with AE,7 cases had a fever,with body temperatures ranging from 37.3°C to 38.9℃,with a mean temperature of 38.2±0.3℃.Four cases experienced local pain,nausea,and vomiting,while two cases of intra-iliac AE showed transient buttock *** patients with adverse reactions were treated symptomatically for 7 *** patients recovered after *** urography of 87 patients in June showed that the renal pelvis and calyces were in good condition,the renal function returned to normal,and the blood urea nitrogen and blood creatinine test results were within the normal *** 1 year of follow-up,no hypertension ***:AE treats MBUS patients in the emergency department with remarkable *** has the advantages of less damage to the body,rapid hemostasis,high safety,and maximum preservation of organ function.

关键词： Emergency Arterial embolism Urinary tract bleeding

Carrier-free nanoprodrug for p53-mutated tumor therapy via concurrent delivery of zinc-manganese dual ions and ROS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生物活性材料(英文) 2023年第2期20卷 404-417页

作者： Jinping Wang Chang Qu Xinyue Shao Guoqiang Song Jingyu Sun donghong shi Ran Jia Hailong An Hongjun Wang Key Laboratory of Molecular Biophysics of Hebei Province Institute of BiophysicsSchool of Health Sciences and Biomedical EngineeringHebei University of Technology300401TianjinPR China Department of Biomedical Engineering Stevens Institute of TechnologyHobokenNJ07030United States Department of Chemistry and Chemical Biology Stevens Institute of TechnologyHobokenNJ07030United States Center for Healthcare Innovation Stevens Institute of TechnologyHobokenNJ07030United States Key Laboratory of Molecular Biophysics of Hebei Province Institute of BiophysicsSchool of SciencesHebei University of Technology300401TianjinPR China State Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Electrical EngineeringHebei University of TechnologyTianjin300130PR China

Human cancers typically express a high level of tumor-promoting mutant p53 protein(Mutp53)with a minimal level of tumor-suppressing wild-type p53 protein(WTp53).In this regard,inducing Mutp53 degradation while activating WTp53 is a viable strategy for precise anti-tumor ***,a new carrier-free nanoprodrug(i.e.,Mn-ZnO_(2)nanoparticles)was developed for concurrent delivery of dual Zn-Mn ions and reactive oxygen species(ROS)within tumor to regulate the p53 protein for high anti-tumor *** response to the mild tumor acidic environment,the released Zn^(2+)and H_(2)O_(2)from Mn-ZnO_(2)NPs induced ubiquitination-mediated proteasomal degradation of Mutp53,while the liberative Mn^(2+)and increased ROS level activated the ATM-p53-Bax pathway to elevate WTp53 *** in vitro and in vivo results demonstrated that pH-responsive decomposition of Mn-ZnO2 NPs could effectively elevate the intracellular dual Zn-Mn ions and ROS level and subsequently generate the cytotoxic hydroxyl radical(·OH)through the Fenton-like *** the integration of multiple functions(i.e.,carrier-free ion and ROS delivery,tumor accumulation,p53 protein modulation,toxic·OH generation,and pH-activated MRI contrast)in a single nanosystem,Mn-ZnO_(2)NPs demonstrate its superiority as a promising nanotherapeutics for p53-mutated tumor therapy.

关键词： p53-mutated tumor therapy Wild-type p53 protein Carrier-free nanoprodrug Mn-ZnO_(2)nanoparticle Reactive oxygen species

Observation on the Clinical Effect of Emergency Interventional Therapy on Acute Severe Non- Variceal Upper Gastrointestinal Bleeding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proceedings of Anticancer Research 2023年第5期7卷 41-46页

作者： Bo Chen donghong shi Min Ai Longjiang Zhang Department of Medical Imaging General Hospital of the Eastern Theater CommandNanjing 210002Jiangsu ProvinceChina

Objective:To observe the clinical effect of emergency interventional therapy for patients with acute severe non-variceal upper gastrointestinal ***:78 patients with acute severe non-variceal upper gastrointestinal bleeding who were treated in the General Hospital of the Eastern Theater Command from May 2020 to May 2023 were randomly divided into two groups according to different treatment *** study group underwent emergency upper gastrointestinal angiography and interventional embolization therapy,the control group was treated with esomeprazole;the clinical data related to the two groups were compared,including the total effective rate of treatment,blood pressure stabilization time,bleeding control time,***:The effective rate of clinical treatment in the study group was 97.44%,which was higher than that in the control group,which was 79.49%(P0.05).Conclusion:Emergency interventional therapy can control bleeding more quickly,shorten bleeding control time and complete hemostasis time,shorten blood pressure stabilization time and abdominal pain relief time,and reduce rebleeding rate in patients with acute severe non-variceal upper gastrointestinal bleeding.

关键词： Upper gastrointestinal bleeding Non-variceal veins Interventional embolization Esomeprazole

基于电磁导航辅助经皮肝穿刺胆管引流术的技术探索

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

医学研究与战创伤救治 2023年第5期36卷 503-508页

作者：杨涛高大志许潭潭史东宏刘丽陈佳海许健徐州医科大学医学影像学院徐州221004 东部战区总医院介入治疗科南京210002 联勤保障部队第九一〇医院肿瘤科泉州362000

目的对比IQQA-Guide智能穿刺导航系统辅助下的经皮肝穿刺胆管引流术(PTBD)与同期的传统PTBD在治疗梗阻性黄疸方面的优劣,为进一步拓展电磁导航辅助PTBD的临床研究及运用提供依据。方法回顾性分析2022年3月至2023年1月56例因恶性梗阻性... 详细信息

目的对比IQQA-Guide智能穿刺导航系统辅助下的经皮肝穿刺胆管引流术(PTBD)与同期的传统PTBD在治疗梗阻性黄疸方面的优劣,为进一步拓展电磁导航辅助PTBD的临床研究及运用提供依据。方法回顾性分析2022年3月至2023年1月56例因恶性梗阻性黄疸于东部战区总医院介入治疗科行PTBD治疗的患者临床资料。按术中穿刺胆管引导方式的不同分为电磁导航组(n=20)、传统透视组(n=36)。分析比较两组患者术前规划穿刺胆管分级及直径、术中穿刺胆管次数、术中透视时间、术中辐射剂量、术后并发症、术后血常规、肝功能等指标改变。结果电磁导航组穿刺的胆管直径小于透视组(P<0.01)。术中电磁导航组在穿刺胆管针数、透视时间、辐射剂量明显优于透视组(P<0.01)。电磁导航组及透视组PTBD的术后TBIL、ALP较术前显著下降(P<0.01)。电磁导航组HB术后变化值较透视组小(P<0.01)。电磁导航组术后3天的CRP、CRP术后变化值低于透视组(P<0.05)。透视组术后HB较术前降低,术后3天CRP较术前升高(P<0.01)。电磁导航组总体并发症发生率明显低于透视组(P<0.05)。结论经电磁导航辅助PTBD术操作简单,安全可行,能有效提高胆管穿刺成功率,减少透视时间及术中辐射,减少患者术后并发症,值得在临床中进一步推广。

关键词：恶性梗阻性黄疸经皮肝穿刺胆管引流术电磁导航影像融合技术

基于二元选择模型对武术参与人群的特征与意愿分析

在线全文

学校读者我要写书评

暂无评论

武术研究 2024年第1期9卷 47-51页

作者：王东红张二鹏石鑫鸿中南财经政法大学公共管理学院湖北武汉430073 湖北经济学院统计与数学学院湖北武汉430205 湖北经济学院国际教育学院湖北武汉430205

文章基于二元选择模型对参加武术活动的人群进行分析,实现了对武术参与人群的画像,运用多元回归模型分别从内因、外因两方面识别人们参与武术意愿的影响因素并进行实证分析。研究表明:武术运动者在参与行为和参与意愿方面均呈现显著性差... 详细信息

文章基于二元选择模型对参加武术活动的人群进行分析,实现了对武术参与人群的画像,运用多元回归模型分别从内因、外因两方面识别人们参与武术意愿的影响因素并进行实证分析。研究表明:武术运动者在参与行为和参与意愿方面均呈现显著性差异;构建的中介模型在一定程度上揭示了武术运动行为的影响机制,为提高武术参与意愿进而激励更多人群参与武术活动提供路径参考。

关键词：武术运动者参与人群意愿分析二元模型

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

新兴林粮——黄精产业发展战略研究

中国工程科学 2024年第2期26卷 113-120页

作者：斯金平裘雨虹孙云娟刘京晶陈东红石艳蒋剑春浙江农林大学黄精产业国家创新联盟杭州311300 中国林业科学研究院林产化学工业研究所南京210042

当前,全球粮食安全形势复杂严峻,与饮食相关的慢性疾病普遍存在,“以健康为中心”“营养多元”“食物即药物”等观点成为普遍共识;利用农业生物多样性来探寻高产且有营养的新一代作物成为国际潮流,黄精具有明显的特色和优势。本文从充... 详细信息

当前,全球粮食安全形势复杂严峻,与饮食相关的慢性疾病普遍存在,“以健康为中心”“营养多元”“食物即药物”等观点成为普遍共识;利用农业生物多样性来探寻高产且有营养的新一代作物成为国际潮流,黄精具有明显的特色和优势。本文从充分发挥黄精潜能的角度出发,系统总结了黄精食药用历史、黄精林粮营养与功效的物质基础、黄精资源分布与粮食生产潜力。现有研究发现,黄精不含淀粉,富含结构复杂、易降解、有能量的果聚糖等营养功效物质,能够服务生命健康;适合林下栽培或与玉米套种,不占良田、不争林地,产能潜力极大,可用于保障粮食安全;适合广大农户种植和加工,经济效益良好,有利于实现共同富裕。为解决黄精林粮产业存在的基础科学研究薄弱、应用技术支撑不足、文化传承与政策支持滞后等问题,需加强黄精基础科学研究、强化黄精全产业链应用技术研究,同时将黄精生产列入木本粮油政策资金保障体系,将黄精应用纳入医疗保健与人口健康规划,将黄精产业列为乡村振兴和共同富裕的重要举措,构建完备的黄精全产业链创新应用体系。

关键词：黄精森林粮食营养成分功效成分生物经济

同方期刊数据库

I COUGH综合气道管理在肝癌患者围术期中的应用

在线全文

学校读者我要写书评

暂无评论

科技通报 2017年第7期33卷 48-51页

作者：胡晨璐金琪何建红施冬虹徐彩娟浙江大学医学院附属第二医院杭州310009

目的:探讨I COUGH综合气道管理对肝癌手术患者呼吸道并发症的临床作用。方法:选取2015年1月至2016年6月本院外科行开放手术的肝癌患者113例进行研究,分为实验组53例与对照组60例,实验组围术期应用I COUGH综合气道管理,对照组围术期应用... 详细信息

目的:探讨I COUGH综合气道管理对肝癌手术患者呼吸道并发症的临床作用。方法:选取2015年1月至2016年6月本院外科行开放手术的肝癌患者113例进行研究,分为实验组53例与对照组60例,实验组围术期应用I COUGH综合气道管理,对照组围术期应用常规气道管理,对比分析两组间的术后呼吸系统并发症发生率和术后平均住院日。结果:实验组的肺不张发生率显著低于对照组(χ2=4.875,P=0.027),但其他呼吸系统并发症发生率并无显著差异(χ2=0.841,P>0.05)。实验组的术后平均住院日显著短于对照组(t=2.557,P=0.012),且实验组肺不张患者术后平均住院日显著短于对照组肺不张患者(t=2.099,P=0.044)。结论:I COUGH综合气道管理能够有效预防肝癌开放手术术后肺不张的发生,并且能够缩短此类并发症相关的术后平均住院日,从而减轻患者的经济负担。

关键词： I COUGH 综合气道管理围术期呼吸系统并发症

基于计划行为理论的生活方式管理在多囊卵巢综合征患者中的应用

在线全文

学校读者我要写书评

暂无评论

中国性科学 2024年第1期33卷 20-24页

作者：史莉张萌罗丽燕韩梅赵月宋东红北京大学第三医院生殖医学中心北京100191

目的评价基于计划行为理论(TPB)的生活方式管理在多囊卵巢综合征(PCOS)患者中的应用效果。方法选取北京大学第三医院2022年1月至8月于生殖中心门诊确诊为PCOS的76例患者作为研究对象,根据患者就诊的先后顺序,将2022年1月至4月确诊的41... 详细信息

目的评价基于计划行为理论(TPB)的生活方式管理在多囊卵巢综合征(PCOS)患者中的应用效果。方法选取北京大学第三医院2022年1月至8月于生殖中心门诊确诊为PCOS的76例患者作为研究对象,根据患者就诊的先后顺序,将2022年1月至4月确诊的41例患者纳入实验组(基于TPB生活方式管理),2022年5月至8月确诊的35例患者纳入对照组(常规生活方式管理)。干预3个月后,比较干预前后两组患者体重指数(BMI)、腰臀比和生活质量。结果干预3个月后,实验组患者BMI和腰臀比均低于对照组(P<0.05),生活质量总分、体质量和不孕症维度得分高于对照组(P<0.05)。结论基于TPB生活方式管理降低了患者的BMI和腰臀比,帮助患者进行健康的生活方式管理,改善了生活质量。

关键词：多囊卵巢综合征生活方式管理计划行为理论生活质量