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Aggregate 2023年第6期4卷 101-109页

作者： dongdong chang Xuetao Xiao Dongyue An Rong Zhang Xianyu Song Yunqi Liu Yan Zhao Xuefeng Lu Department of Materials Science State Key Laboratory of Molecular Engineering of PolymersFudan UniversityShanghaiChina Key Laboratory of Water Environment Evolution and Pollution Control in Three Gorges Reservoir School of Environmental and Chemical EngineeringChongqing Three Gorges UniversityChongqingChina

A series of newπ-conjugated macrocycles(AzoM-n-E,n 1–3)incorporating=azobenzene units have been synthesized by a facile strategy in one-pot reaction.The resultant azobenzene-embedded macrocycles feature intrinsic photoresponsive behaviors and intriguing supramolecular assembling properties.The smallest macro-cycle AzoM-1-E with a rigid planar conjugated backbone structure is used to prepare the single crystal transistors,showing reversible optical tunability.The moderate size macrocycle AzoM-2-E assembles into a dimer in the form of interpenetration throughπ-πstacking between azobenzene units.The largest macrocycle AzoM-3-E with enhancedﬂexibility can adaptively assemble with various types of electron-deﬁcient guests accompanied by distortion of azobenzene.Typically,AzoM-3-E assembles with the planar F4-TCNQ to form a tetragonal geometry by C-F⋅⋅⋅π and π-π interactions,while the assembly with ellipsoidal C70 viaπ-πinteractions induces AzoM-3-E to form a boat-shaped geometry.This work will shed new light on the development of functional conjugated macrocycles in organic electronics.

关键词： azobenzene conjugated macrocycle host-guest interaction photoresponsive transistors supramolecular assembly

Inhibitor tolerance and bioethanol fermentability of levoglucosan-utilizing Escherichia coli were enhanced by overexpression of stress-responsive gene ycfR:The proteomics-guided metabolic engineering

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Synthetic and Systems Biotechnology 2021年第4期6卷 384-395页

作者： dongdong chang Zia Ul Islam Junfang Zheng Jie Zhao Xiaoyong Cui Zhisheng Yu College of Resources and Environment University of Chinese Academy of SciencesBeijing100049PR China Department of Chemistry Mississippi State UniversityMississippi StateMS 39762USA Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijing100069PR China Yanshan Earth Critical Zone and Surface Fluxes Research Station Chinese Academy of SciencesNo.380 Huaibei TownHuairou DistrictBeijing101408PR China RCEES-IMCAS-UCAS Joint-Lab of Microbial Technology for Environmental Science Beijing100085PR China

Pretreatment of lignocellulosic biomass is crucial for the release of biofermentable sugars for biofuels production,which could greatly alleviate the burgeoning environment and energy crisis caused by the massive usage of traditional fossil fuels.Pyrolysis is a cost-saving pretreatment process that can readily decompose biomass into levoglucosan,a promising anhydrosugar;however,many undesired toxic compounds inhibitory to downstream microbial fermentation are also generated during the pyrolysis,immensely impeding the bioconversion of levoglucosan-containing pyrolysate.Here,we took the first insight into the proteomic responses of a levoglucosan-utilizing and ethanol-producing Escherichia coli to three representative biomass-derived inhibitors,identifying large amounts of differentially expressed proteins(DEPs)that could guide the downstream metabolic engineering for the development of inhibitor-resistant strains.Fifteen up-and eight down-regulated DEPs were further identified as the biomarker stress-responsive proteins candidate for cellular tolerance to multiple inhibitors.Among these biomarker proteins,YcfR exhibiting the highest expression fold-change level was chosen as the target of overexpression to validate proteomics results and develop robust strains with enhanced inhibitor tolerance and fermentation performance.Finally,based on four plasmid-borne genes encoding the levoglucosan kinase,pyruvate decarboxylase,alcohol dehydrogenase,and protein YcfR,a new recombinant strain E.coli LGE-ycfR was successfully created,showing much higher acetic acid-,furfural-,and phenol-tolerance levels compared to the control without overexpression of ycfR.The specific growth rate,final cell density,ethanol concentration,ethanol productivity,and levoglucosan consumption rate of the recombinant were also remarkably improved.From the proteomics-guided metabolic engineering and phenotypic observations,we for the first time corroborated that YcfR is a stress-induced protein responsive to multiple biomass-derived inhibitors,and al

关键词： Lignocellulosic biomass Levoglucosan Inhibitor Proteomics Gene overexpression Bioethanol

Laser Powder Bed Fusion of Beta-Type Titanium Alloys for Biomedical Application:A Review

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Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 17-28页

作者： Xuan Luo Chao Yang dongdong Li Lai-chang Zhang State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan430074China National Engineering Research Center of Near-Net-Shape Forming for Metallic Materials Guangdong Provincial Key Laboratory for Processing and Forming of Advanced Metallic MaterialsSouth China University of TechnologyGuangzhou510640China Centre for Advanced Materials and Manufacturing School of EngineeringEdith Cowan University270 Joondalup DriveJoondalupPerthWA6027Australia

Additive manufacturing ofβ-type titanium alloy is expected to replace Ti-6Al-4V alloy in the field of orthopedic implantation because of their low elastic modulus,excellent corrosion resistance,and biocompatibility.After briefly introducing the laser powder bed fusion(LPBF)process and physical phenomena,this paper reviews the recent progresses in LPBF-edβ-type Ti alloys.The strategies to strengthening and tougheningβ-type Ti alloys are critically reviewed.This is followed by the processing routes employed to achieve to low modulus for orthopedic applications,especially a new methodology for tailoring crystallographic orientation called multi-track coupled directional solidification.The effect of processing and compositions on performance metrics ofβ-type Ti alloys included corrosion behavior,and biocompatibility is reviewed.In the end,challenges in additive manufacturing ofβ-type Ti alloys in future are highlighted,with the aim to ensue clinical application of LPBF-edβ-type Ti alloys.

关键词： β-type Ti alloys Laser powder bed fusion Mechanical properties Elastic modulus Biocompatibility

LSM14B coordinates protein component expression in the P-body and controls oocyte maturation

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Journal of Genetics and Genomics 2024年第1期51卷 48-60页

作者： Huiru Zhang Tao Zhang Xiang Wan chang Chen Shu Wang dongdong Qin Lufan Li Luping Yu Xin Wu State Key Laboratory of Reproductive Medicine and Offspring Health Nanjing Medical UniversityNanjingJiangsu 210029China Center for Reproductive Medicine and Obstetrics and Gynecology Nanjing Drum Tower HospitalNanjing University Medical SchoolNanjingJiangsu 210029China

The generation of mature and healthy oocytes is the most critical event in the entire female reproductive process,and the mechanisms regulating this process remain to be studied.Here,we demonstrate that Smith-like(LSM)family member 14B(LSM14B)regulates oocyte maturation,and the loss of LSM14B in mouse ovaries leads to abnormal oocyte MII arrest and female infertility.Next,we find the aberrant transcriptional activation,indicated by abnormal non-surrounded nucleolus and surrounded nucleolus oocyte proportions,and abnormal chromosome assembly and segregation in Lsm14b-deficient mouse oocytes.The global transcriptome analysis suggests that many transcripts involved in cytoplasmic processing body(P-body)function are altered in Lsm14b-deficient mouse oocytes.Deletion of Lsm14b results in the expression and/or localization changes of P-body components(such as LSM14A,DCP1A,and 4E-T).Notably,DDX6,a key component of the P-body,is downregulated and accumulates in the nuclei in Lsm14b-deficient mouse oocytes.Taken together,our data suggest that LSM14B links mouse oocyte maturation to female fertility through the regulation of the P-body.

关键词： LSM14B P-body DDX6 MIl arrest Chromatin configuration

Multi-Scale Pore Structure Heterogeneity in Tuff Reservoirs Investigated with Multi-Experimental Method and Fractal Dimensions in chang 7 Formation,Southern Ordos Basin

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Journal of Earth Science 2024年第2期35卷 666-686页

作者： Hao Lu Qing Li Dali Yue dongdong Xia Shenghe Wu Lang Wen Yu He State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China College of Geosciences China University of PetroleumBeijing102249China Petroleum Exploration and Development Institute of SINOPEC Beijing100083China

The tight tuff reservoir is an unusual type of unconventional reservoir with strong heterogeneity.However,there is a lack of research on the microscopic pore structure that causes the heterogeneity of tuff reservoirs.Using the chang 7 Formation in Ordos Basin,China as a case study,carbon-dioxide gas adsorption,nitrogen gas adsorption and high-pressure mercury injection are integrated to investigate the multi-scale pore structure characteristics of tuff reservoirs.Meanwhile,the fractal dimension is introduced to characterize the complexity of pore structure in tuff reservoirs.By this multi-experimental method,the quantitative characterizations of the full-range pore size distribution of four tuff types were obtained and compared in the size ranges of micropores,mesopores and macropores.Fractal dimension curves derived from full-range pores are divided into six segments as D1,D2,D3,D4,D5 and D6 corresponding to fractal characteristics of micropores,smaller mesopores,larger mesopores,smaller macropores,medium macropores and larger macropores,respectively.The macropore volume,average macropore radius and fractal dimension D5 significantly control petrophysical properties.The larger macropore volume,average macropore radius and D5 correspond to favorable pore structure and good reservoir quality,which provides new indexes for the tuff reservoir evaluation.This study enriches the understanding of the heterogeneity of pore structures and contributes to unconventional oil and gas exploration and development.

关键词： tuff reservoir pore structure carbon-dioxide gas adsorption nitrogen gas adsorption high-pressure mercury injection fractal dimension petroleum geology

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基于视觉的超窄间隙焊接坡口宽度测量方法

传感器与微系统 2022年第11期41卷 117-121页

作者：何倩玉张爱华常东东任乐兰州理工大学电气工程与信息工程学院甘肃兰州730050 甘肃省工业过程先进控制重点实验室甘肃兰州730050 兰州理工大学电气与控制工程国家级实验教学示范中心甘肃兰州730050

针对超窄间隙焊接因坡口窄且深的结构特点而导致当前焊道坡口宽度难以直接测量的问题,提出一种基于视觉和焊接热变形模型的当前焊道坡口宽度软测量方法。为克服激光线投射于焊件表面所造成的亮度分布不均,二值化阈值难以确定的问题,提... 详细信息

针对超窄间隙焊接因坡口窄且深的结构特点而导致当前焊道坡口宽度难以直接测量的问题,提出一种基于视觉和焊接热变形模型的当前焊道坡口宽度软测量方法。为克服激光线投射于焊件表面所造成的亮度分布不均,二值化阈值难以确定的问题,提出使用顶帽变换与Otsu共同作用的方法,将激光线灰度均衡化的同时从背景中有效分离,骨架法和最小二乘法相结合可准确提取单像素的激光条纹中心线并对特征点识别,完成上坡口宽度的测量。依据坡口角变形量与焊缝厚度关系,建立当前焊道坡口宽度计算模型。实验结果表明:此方法可以实现超窄间隙厚板焊接上下坡口宽度的准确测量,且最大误差不超过0.2 mm,能满足超窄焊接工艺参数设定对坡口宽度测量精度的要求。

关键词：超窄间隙焊接激光视觉测量系统顶帽变换焊接热变形模型坡口宽度

Integrated and holistic knowledge map of phase change materials for pavement: A scientometric analysis and bibliometric review

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Journal of Traffic and Transportation Engineering(English Edition) 2024年

作者： Jiasheng Dai Feng Ma Zhen Fu Chen Li Yingjie Hou Yalu Wen Yanzhe Zou dongdong Yuan Wenhao Dong Ke Shi Key Laboratory for Special Area Highway Engineering of Ministry of Education chang'an University School of Material and Science Engineering chang'an University

Elevated pavement temperatures contribute to the urban heat island effect and pose a risk of thermal damage to pavement. Thus， regulating pavement temperature is paramount to ensure its longevity， enhance traffic safety， and preserve the environment. Phase change materials (PCMs) with the latent heat characteristic can store and release thermal energy via phase transitions. PCMs can effectively control pavement structure temperatures within a relatively narrow range， mitigating thermal stress on asphalt pavements. This research aims to explore the current status and emerging trends in PCM Integrated Pavement Engineering (PCMIPE) using the CiteSpace visual analysis tool. Relevant publications were systematically curated from the Web of Science core database， spanning 2011 to 2023. Subsequently， the co-authorships network maps (country， institution， author)， co-cited network maps (co-cited journals， authors， and references)， and keyword co-occurrence network maps were constructed to analyze the principal contributions in the PCMIPE field comprehensively. This analysis provides an understanding of the field's strengths， research domains， and knowledge structure and identifies current research focal points and emerging frontiers. The findings reveal that research within the PCMIPE field is still in its early stages， with a predominant emphasis on material design and performance assessment. Additionally， future research is anticipated to expand into economic analyses and exploration of environmental effects when integrating PCMs into pavement engineering. Furthermore， there is an emerging interest in investigating the synergy of PCMs with other functional pavement technologies. These results underscore the potential of the PCMIPE field and emphasize the importance of future research endeavors.

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大杭州海洋体育旅游圈的构建与发展策略研究

济宁学院学报 2013年第6期34卷 74-77,82页

作者：常冬冬浙江旅游职业学院社科部浙江杭州311231

浙江省有着丰富的海洋旅游资源和雄厚的经济基础,为海洋体育旅游产业的发展提供了有力保证和支撑.以杭州做为海洋体育旅游圈的核心城市,既有国内外知名的旅游资源,又在政治、经济、文化、交通等方面带动周边内陆和沿海城市旅游产业的发... 详细信息

浙江省有着丰富的海洋旅游资源和雄厚的经济基础,为海洋体育旅游产业的发展提供了有力保证和支撑.以杭州做为海洋体育旅游圈的核心城市,既有国内外知名的旅游资源,又在政治、经济、文化、交通等方面带动周边内陆和沿海城市旅游产业的发展和旅游目的地知名度的提升.实施海陆联动、政府引导、健全管理、创建品牌、优化结构、加强营销等策略,从而实现构建"一核两翼三区"的大杭州海洋体育旅游圈的布局,能够促进浙江省体育旅游产业的发展,提升浙江省海洋体育休闲旅游的国际竞争力.

关键词：大杭州海洋体育旅游策略

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后奥运时代发展浙江省体育节事旅游的研究

河北旅游职业学院学报 2009年第4期14卷 38-41页

作者：常冬冬浙江旅游职业学院浙江杭州311231

奥运会是一种大型的体育节事,能够对举办地的旅游业产生了深远影响,其中的体育旅游业也获益匪浅。我国的体育旅游业虽然起步较晚,但发展势头良好。我国举办北京奥运会的圆满成功,使体育旅游业发展获得了前所未有的巨大机遇和挑战。浙江... 详细信息

奥运会是一种大型的体育节事,能够对举办地的旅游业产生了深远影响,其中的体育旅游业也获益匪浅。我国的体育旅游业虽然起步较晚,但发展势头良好。我国举办北京奥运会的圆满成功,使体育旅游业发展获得了前所未有的巨大机遇和挑战。浙江省是我国的经济强省,在重视体育的同时,不忘依托浙江旅游资源丰富、旅游产业较发达的有利条件,拓展体育旅游业的发展空间。

关键词：浙江省体育节事体育旅游发展

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高校学校体育信息化管理模式的研究

湖北体育科技 2007年第5期26卷 593-595页

作者：常冬冬平顶山学院河南平顶山467002

以计算机为主的现代信息技术在国民经济和社会发展中起到越来越重要的作用,高校体育信息化管理模式主要从体育教学课程管理,体育信息资料管理,体育网络资源管理,学生信息成绩管理,体育科研活动管理,体育师资力量管理几个方面实施,对高... 详细信息

以计算机为主的现代信息技术在国民经济和社会发展中起到越来越重要的作用,高校体育信息化管理模式主要从体育教学课程管理,体育信息资料管理,体育网络资源管理,学生信息成绩管理,体育科研活动管理,体育师资力量管理几个方面实施,对高校实施学校体育信息化管理具有一定的参考价值。

关键词：高校学校体育信息化管理模式