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Burden landscape of hepatobiliary and pancreatic cancers in Chinese young adults:30 years’overview and forecasted trends

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World Journal of Gastrointestinal Oncology 2024年第10期16卷 4177-4193页

作者： De-Sheng Chen Ze-Ping Chen dong-zi zhu Lv-Xin Guan Qi zhu Yi-Chao Lou Ze-Ping He Hao-Nan Chen Hong-Cheng Sun Department of General Surgery Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Department of General Surgery Shanghai Ninth People's HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Shenzhen Institute of Translational Medicine The First Affiliated Hospital of Shenzhen UniversityShenzhen 518035Guangdong ProvinceChina Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

BACKGROUND Hepatobiliary and pancreatic(HBP)cancers impose a considerable burden on young populations(aged 15 to 49 years),resulting in a substantial number of new cases and fatalities each *** young populations,the HBP cancers shows extensive variance worldwide and the updated data in China is *** To investigate the current status,trends,projections,and underlying risk factors of HBP cancers among young populations in *** The Global Burden of Disease Study 2019 provided data on the annual incidence,mortality,disability-adjusted life years(DALYs),age-standardized incidence rate(ASIR),mortality rate(ASMR),and DALYs rate(ASDR)of HBP cancers in young Chinese adults between 1990 and *** trends were assessed using estimated annual percentage change and hierarchical ***-specific mortality and DALYs caused by various risks were analyzed across China and other regions,with future trends until 2035 projected using the Bayesian age-period-cohort *** From 1990 to 2019,incident cases,deaths,DALYs,ASIR,ASMR,and ASDR for liver cancer(LC)in young Chinese individuals decreased,classified into'significant decrease'***,cases of gallbladder and biliary tract cancer and pancreatic cancer rose,categorized as either'significant increase'or'minor increase'*** contribution of risk factors to mortality and DALYs for HBP tumors increased to varying *** lifestyle behaviors,such as tobacco control,weight management,alcohol moderation,and drug avoidance,could lower HBP cancers ***,except for LC in females,which is likely to initially decline slightly and then rise,the forecasting model predicted that the ASIR and ASMR for all HPB cancers subtypes by gender will increase among young *** HBP cancers burden among young adults in China is expected to increase until 2035,necessitating lifestyle interventions and targeted treatment strategies to mitigate the public health impact of these

关键词： Hepatobiliary and pancreatic cancers Burden landscape Young adults Projection China

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Mechanical performance of 22SiMn2TiB steel welded with lowtransformation- temperature filler wire and stainless steel filler wire

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Journal of Iron and Steel Research International 2024年第4期31卷 967-981页

作者： zi-dong Lin Kai-jie Song Zhen Sun zi-qian zhu Xue-feng Zhao Constantinos Goulas Wei Ya Xing-hua Yu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China Department of Design Production and Management Faculty of Engineering Technology.University of TwenteEnschede 7500 AETheNetherlands Rotterdam Additive Manufacture Fieldlab(RAMLAB) Rotterdam 3089 JWTheNetherlands

TX-80 low-transformation-temperature(LTT)welding wire was used to replace the traditional ER 307Si welding wire to realize the connection of 22SiMn2TiB armor steel in manual overlay *** previously existing issues,such as welding cracks,large welding deformation,and severe welding residual stress,were solved to ensure good strength and ductility *** particular,with the same welding conditions,TX-80 LTT wire eliminates welding *** reduces the welding deformation no matter the base pretreatment of pre-setting angle or no pre-setting *** comparison,it was found that the microstructure at the TX-80 weld is mainly composed of martensite and a small amount of retained *** contrast,the microstructure of the ER 307Si weld consists of a large amount of austenite and a small amount of skeleton-like *** variation trend of residual stress and microhardness from the weld to the base were investigated and compared with the mechanical properties of base *** TX-80 and the ER 307Si tensile samples elongation is 6.76%and 6.01%,while the ultimate tensile strengths are 877 and 667 MPa,*** average impact toughness at room temperature of the ER 307Si weld is 143.9 J/cm^(2),much higher than that of the TX-80 weld,which is only 36.7 J/cm^(2).The relationship between impact and tensile properties with microstructure species and distribution was *** addition,the fracture surface of the tensile and the impact samples was observed and *** dimples,fewer pores,larger radiation zone,and shear lips of TX-80 samples indicate better tensile ductility and worse impact toughness than those of ER 307Si weld.

关键词： Low-transformation-temperature material 22SiMn2TiB steel Welding deformation Residual stress Martensitic transformation Mechanical property

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Reliable calculations of nuclear binding energies by the Gaussian process of machine learning

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Nuclear Science and Techniques 2024年第6期35卷 130-144页

作者： zi-Yi Yuan dong Bai Zhen Wang Zhong-Zhou Ren School of Physics Science and Engineering Tongji UniversityShanghai 200092China College of Science Hohai UniversityNanjing 211100China Key Laboratory of Advanced Micro-Structure Materials Ministry of EducationShanghai 200092China

Reliable calculations of nuclear binding energies are crucial for advancing the research of nuclear physics. Machine learning provides an innovative approach to exploring complex physical problems. In this study, the nuclear binding energies are modeled directly using a machine-learning method called the Gaussian process. First, the binding energies for 2238 nuclei with Z > 20 and N > 20 are calculated using the Gaussian process in a physically motivated feature space, yielding an average deviation of 0.046 MeV and a standard deviation of 0.066 MeV. The results show the good learning ability of the Gaussian process in the studies of binding energies. Then, the predictive power of the Gaussian process is studied by calculating the binding energies for 108 nuclei newly included in AME2020. The theoretical results are in good agreement with the experimental data, reflecting the good predictive power of the Gaussian process. Moreover, the α-decay energies for 1169 nuclei with 50 ≤ Z ≤ 110 are derived from the theoretical binding energies calculated using the Gaussian process. The average deviation and the standard deviation are, respectively, 0.047 MeV and 0.070 MeV. Noticeably, the calculated α-decay energies for the two new isotopes ^ (204 )Ac(Huang et al. Phys Lett B 834, 137484(2022)) and ^ (207) Th(Yang et al. Phys Rev C 105, L051302(2022)) agree well with the latest experimental data. These results demonstrate that the Gaussian process is reliable for the calculations of nuclear binding energies. Finally, the α-decay properties of some unknown actinide nuclei are predicted using the Gaussian process. The predicted results can be useful guides for future research on binding energies and α-decay properties.

关键词： Nuclear binding energies decay Machine learning Gaussian process

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A General Simulation Method for Complex Deformation of Irregular-Shaped Origami Configurations

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Acta Mechanica Solida Sinica 2024年第1期37卷 90-98页

作者： Zhaochen dong Yichao zhu Xu Guo State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsInternational Research Center for Computational MechanicsDalian University of TechnologyDalian 116023China

Most existing treatments for origami-folding simulations have focused on regular-shaped *** article aims to introduce a general strategy for simulating and analyzing the deformation process of irregular shapes by means of computational capabilities *** better simulate origami deformation with folding orders,the concept of plane follow-up is introduced to achieve automated computer simulation of complex folding patterns,thereby avoiding intersection and penetration between *** on the evaluation criteria such as the lowest storage energy with tightening and the fastest pace from tightening to unfolding,the optimal crease distribution patterns for four irregular(‘N’-,‘T’-,‘O’-,and‘P’-shaped)origami configurations are then presented under five *** the dimensions of the origami are fixed,it is discovered that simpler folding patterns lead to faster deformation of the origami *** the folding complexity is fixed,higher strain energy results in more rapid origami expansion.

关键词： Irregular-shaped origami Complex deformation Computer-aided origami design General simulation

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C@Ag core‒shell structure as lubricating additives towards high efficient lubrication

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Friction 2024年第9期12卷 1991-2003页

作者： dong AO Xiaoqiang FAN Minhao zhu Key Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China Tribology Research Institute School of Mechanical EngineeringSouthwest Jiaotong UniversityChengdu 610031China

Efficient cooperative lubrication can be achieved via the introduction of core‒shell structure lubricant additives with hard core and soft shell,for obtaining the expected anti-wear performance from the structural changes in the friction *** this study,C@Ag microspheres with a core‒shell structure were prepared by the redox method with carbon spheres as the core and Ag nanoparticles as the *** tribological behaviors as base oil(G1830)additive with different concentrations were investigated in *** with base oil,the addition of C@Ag particles at 0.5 wt%can reduce the coefficient of friction(COF)and wear volume(Wv)up to 15.5%and 88%,*** importantly,C@Ag particles provide superior lubrication performance to single additive(like carbon sphere(CS)and Ag nanoparticle).C@Ag core‒shell particles contribute to the formation of tribo-film by melt bonding of flexible Ag and carbon sphere(CS)toward excellent self-repair performance and high-efficiency ***,core‒shell structural nanoparticles with hard-core and soft-shell hold bright future for high-performance lubrication application.

关键词： C@Ag microspheres tribo-film self-repair performance high-efficiency lubrication

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Could π-aromaticity cross an unsaturated system to a fully saturated one?

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Chinese Chemical Letters 2024年第6期35卷 298-302页

作者： Shicheng dong Jun zhu State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials(iChem)Fujian Provincial Key Laboratory of Theoretical and Computational ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China

The classification of π-/σ-aromaticity depends on the electrons with the dominating ***,π-andσ-aromaticity are used to describe the unsaturated and saturated systems,***,it is rarely reported that π-aromaticity is dominated in a saturated *** we demonstrate that π-aromaticity could be dominating in several fully saturated four-membered rings(4MRs),supported by various aromaticity indices including ΔBL,NICS,EDDB,MCI,and Ad *** origin of suchπ-aromaticity in saturated rings could be attributed to an introduction of two additional electrons into the π-type LUMO of the parent neutral *** findings represent a novel approach to achieve π-aromaticity into a fully saturated system which has traditionally been dominated by σ-aromaticity.

关键词： π-Aromaticity Saturated rings Silicon

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Carbon nanofibers embedded with Fe-Co alloy nanoparticles via electrospinning as lightweight high-performance electromagnetic wave absorbers

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Rare Metals 2024年第6期43卷 2769-2783页

作者： Wen-Jun Cai Jian-Guo Jiang zi-dong Zhang zi-Xuan Liu Lu-JieZhang Zhen-Kun Long Ke Bi Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials(Ministry of Education) Shandong UniversityJinan 250061China School of Materials Science and Engineering Shandong UniversityJinan 250061China Energy Institute Qilu University of Technology(Shandong Academy of Sciences)Jinan 250014China State Key Laboratory of Information Photonics and Optical Communications School of ScienceBeijing University of Posts and TelecommunicationsBeijing 100876China

As a lot of electromagnetic pollution and interference issues have emerged,to overcome electromagnetic interference,prevent electromagnetic hazards,and develop new high-performance electromagnetic wave(EMW)absorbers have become a significant task in the field of materials *** this paper,a three-dimensional(3D)carbon nanofibers network with core-shell structure,embedded with varied molar ratios of iron and cobalt(4:0,3:1,2:2,1:3,0:4),was effectively synthesized(Fe/Co@C-CNFs)via *** phase,microstructure,magnetic and EMW absorption properties were *** is discovered that Fe/Co@C-CNFs doped with iron:cobalt=1:1 have excellent EMW absorption *** the matching thickness is 1.08 mm,the minimum reflection loss(RL)value is-18.66 dB,while the maximum effective absorption bandwidth(EAB)reaches 4.2 GHz(13.9-18 GHz)at a thickness of 1.22 *** is owing to the absorbers'superior impedance matching and multiple reflections as well as the conductivity,dielectric,and magnetic losses of carbon nanofibers embedded with Fe-Co alloy *** addition,the radar cross section(RCS)of the absorbers has been calculated by CST Studio Suite,showing that the absorbing coating can effectively reduce the RCS at various angles,especially for Fe/Co@C-CNFs doped with iron:cobalt=1:*** findings not only provide new insights for the preparation of light-weight and high-performance electromagnetic wave absorbers,but also contribute to energy storage and conversion.

关键词： Electromagnetic wave(EMW)absorbers Fe/Co@C-CNFs Core-shell structure EMW absorbing mechanism Radar cross section(RCS)

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Tumor recurrence and survival prognosis in patients with advanced gastric cancer after radical resection with radiotherapy and chemotherapy

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1660-1669页

作者： Shuang-Fa Nie Chen-Yang Wang Lei Li Cheng Yang zi-Ming zhu Jian-dong Fei Department of General Surgery The First Affiliated Hospital of Hebei North UniversityZhangjiakou 75000Hebei ProvinceChina Department of Gastrointestinal Surgery Zhongshan Hospital of Fudan UniversityShanghai 200032China

BACKGROUND Advanced gastric cancer is a common malignancy that is often diagnosed at an advanced stage and is still at risk of recurrence after radical surgical ***,as one of the important treatment methods for gastric cancer,is of great significance for improving the survival rate of ***,the tumor recurrence and survival prognosis of gastric cancer patients after radio-therapy and chemotherapy are still *** To analyze the tumor recurrence after radical radiotherapy and chemotherapy for advanced gastric cancer and provide more in-depth guidance for *** A retrospective analysis was performed on 171 patients with gastric cancer who received postoperative adjuvant radiotherapy and chemotherapy in our hospital from 2021 to *** Kaplan-Meier method was used to calculate the recurrence rate and survival rate;the log-rank method was used to analyze the single-factor prognosis;and the Cox model was used to analyze the prognosis associated with multiple *** The median follow-up time of the whole group was 63 months,and the follow-up rate was 93.6%.Stage Ⅱ and Ⅲ patients accounted for 31.0%and 66.7%,*** incidences of Grade 3 and above acute gastrointestinal reactions and hematological adverse reactions were 8.8%and 9.9%,respectively.A total of 166 patients completed the entire chemoradiotherapy regimen,during which no adverse reaction-related deaths *** terms of the recurrence pattern,17 patients had local recurrence,29 patients had distant metastasis,and 12 patients had peritoneal implantation *** 1-year,3-year,and 5-year overall survival(OS)rates were 83.7%,66.3%,and 60.0%,*** 1-year,3-year,and 5-year disease-free survival rates were 75.5%,62.7%,and 56.5%,*** analysis revealed that T stage,peripheral nerve invasion,and the lymph node metastasis rate(LNR)were independent prognostic factors for *** Postoperative intensity-

关键词： Tumor recurrence Survival prognosis Advanced gastric cancer Radical resection Retrospective study

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Sequence structure controllable polymerization-induced self-assembly

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Science China Chemistry 2024年第1期67卷 390-397页

作者： zi-Xuan Chang Ren-Man zhu Chun-Yan Hong Wen-Jian Zhang Department of Polymer Science and Engineering University of Science and Technology of ChinaHefei 230026China Institute of Physical Science and Information Technology Anhui UniversityHefei 230601China Key Laboratory of Environment-Friendly Polymeric Materials of Anhui Province Anhui UniversityHefei 230601China

Polymerization-induced self-assembly(PISA)combines synthesis and self-assembly of artificial polymers in one-pot,which brings us one step closer to emulating ***,the reported PISA formulations primarily focus on developing nano-objects with new chemical compositions and rarely on structural regulation of polymers with specific ***,sequence structure controllable polymerization-induced self-assembly(SCPISA)is reported by using 7-(2-methacryloyloxyethoxy)-4-methylcoumarin(CMA)as a *** the copolymerization of 2-hydroxyethyl methacrylate(HEMA)and CMA,controlled incorporation of CMA units into the polymer chains can be realized by programmable light/heat ***-based P(HEMA-co-CMA)copolymers with the same composition but different sequence structures generate a range of ***,the morphologies of the resultant nano-objects can also be controlled by regulating the feed molar ratio of CMA and HEMA,which is similar to the conventional PISA,but the synthesis procedure is obviously simplified in *** versatility of the methodology is further demonstrated by the fabrication of different functional nano-objects with sequence structure-dependent morphologies in SCPISA systems with different functional monomers.

关键词： polymerization-induced self-assembly sequence-controlled polymers PET-RAFT polymerization

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Synthesis methods and powder quality of titanium monocarbide

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Chinese Journal of Chemical Engineering 2024年第8期72卷 10-18页

作者： Maoqiao Xiang Wenjun Ding Qinghua dong Qingshan zhu State Key Laboratory of Mesoscience and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of the Chinese Academy of SciencesBeijing 100049China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China

Titanium monocarbide(TiC),which is the most stable titanium-based carbide,has attracted considerable interest in the fields of energy,catalysis,and structural materials due to its excellent *** of high-quality TiC powders with low cost and high efficiency is crucial for industrial applications;however major challenges face its ***,the methods for synthesizing TiC powders based on a reaction system are *** analysis is focused on the underlying mechanisms by which synthesis methods affect the quality of ***,strategies for improving the synthesis of highquality powders are analyzed from the perspective of enhancing heat and mass transfer ***,the critical issues,challenges,and development trends of the synthesis technology and application of high-quality TiC powder are discussed.

关键词： Titanium carbide Synthesis methods Reaction engineering Reaction kinetics Powder technology

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