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Digital Twins for Wastewater Treatment:A Technical Review

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Engineering 2024年第5期36卷 21-35页

作者： Ai-Jie Wang Hewen Li Zhejun He yu Tao Hongcheng Wang min Yang Dragan Savic Glen TDaigger Nanqi Ren School of Civil and Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150090China Department of Civil and Environmental Engineering Cornell UniversityIthacaNY 14850USA BIOMATH Department of Data Analysis and Mathematical ModellingGhent UniversityGhent 9000Belgium KWR Water Research Institute Nieuwegein 3430 BBNetherlands Centre for Water Systems University of ExeterExeter EX44QFUK Department of Civil and Environmental Engineering University of MichiganAnn ArborMI 48109USA

The digital twins concept enhances modeling and simulation through the integration of real-time data and *** review elucidates the foundational elements of digital twins,covering their concept,entities,domains,and key *** specifically,we investigate the transformative potential of digital twins for the wastewater treatment engineering *** discussion highlights the application of digital twins to wastewater treatment plants(WWTPs)and sewage networks,hardware(i.e.,facilities and pipes,sensors for water quality and activated sludge,hydrodynamics,and power consumption),and software(i.e.,knowledge-based and data-driven models,mechanistic models,hybrid twins,control methods,and the Internet of Things).Furthermore,two cases are provided,followed by an assessment of current challenges in and perspectives on the application of digital twins in *** review serves as an essential primer for wastewater engineers navigating the digital paradigm shift.

关键词： Digital twins Urban water systems Wastewater treatment

Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution

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General Psychiatry 2024年第3期37卷 375-387页

作者： Wenxiang Cai Weichen Song Shunying yu min Zhao Guan Ning Lin Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineSchool of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders ShanghaiChina

Background The role of human lineage mutations(HLMs)in human evolution through post-transcriptional modification is *** To investigate the contribution of HLMs to human evolution through post-transcriptional *** We applied a deep learning model Seqweaver to predict how HLMs impact RNA-binding protein *** We found that only 0.27%of HLMs had significant impacts on RNA-binding proteins at the threshold of the top 1%of human common *** HLMs enriched in a set of conserved genes highly expressed in adult excitatory neurons and prenatal Purkinje neurons,and were involved in synapse organisation and the GTPase *** genes also carried excess damaging coding mutations that caused neurodevelopmental disorders,ataxia and *** these genes,NTRK2 and ITPR1 had the most aggregated evidence of functional importance,suggesting their essential roles in cognition and *** Our findings suggest that a small subset of human-specific mutations have contributed to human speciation through impacts on post-transcriptional modification of critical brain-related genes.

关键词： evolution conserved Human

Heparin is an effective treatment for preventing liver failure after hepatectomy

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World Journal of Gastroenterology 2024年第22期30卷 2881-2892页

作者： Zhi-Ying Xu min Peng ming-ming Fan Qi-Fei Zou Yi-Ran Li dong Jiang Hepatic Surgery IV Shanghai Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China Ultrasound Diagnosis PLA Naval Medical CenterShanghai 200437China Department of Ultrasound Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai 200433China

BACKGROUND Posthepatectomy liver failure(PHLF)is one of the most important causes of death following liver ***,an established anticoagulant,can protect liver function through a number of mechanisms,and thus,prevent liver *** To look at the safety and efficacy of heparin in preventing hepatic dysfunction after *** The data was extracted from Multiparameter Intelligent Monitoring in Intensive Care III(MIMIC-III)v1.4 pinpointed patients who had undergone hepatectomy for liver cancer,subdividing them into two cohorts:Those who were injected with heparin and those who were *** statistical evaluations used were unpaired ttests,Mann-Whitney U tests,chi-square tests,and Fisher’s exact tests to assess the effect of heparin administration on PHLF,duration of intensive care unit(ICU)stay,need for mechanical ventilation,use of continuous renal replacement therapy(CRRT),incidence of hypoxemia,development of acute kidney injury,and ICU *** regression was utilized to analyze the factors related to PHLF,with propensity score matching(PSM)aiming to balance the preoperative disparities between the two *** In this study,1388 patients who underwent liver cancer hepatectomy were *** yielded 213 matched pairs from the heparin-treated and control *** univariate analyses indicated that heparin potentially reduces the risk of PHLF in both matched and unmatched *** analysis in the matched cohorts confirmed a significant association,with heparin reducing the risk of PHLF(odds ratio:0.518;95%confidence interval:0.295-0.910;P=0.022).Additionally,heparin treatment correlated with improved short-term postoperative outcomes such as reduced ICU stay durations,diminished requirements for respiratory support and CRRT,and lower incidences of hypoxemia and ICU *** Liver failure is an important hazard following hepatic *** ICU care heparin administration has been proved to decr

关键词： Liver resection Posthepatectomy liver failure Prophylactic treatment Heparin Prognosis of hepatectomy

New Second-Level-Discrete Zeroing Neural Network for Solving Dynamic Linear System

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1521-1523页

作者： min Yang School of Robotics Hunan UniversityChangsha 410082China

Dear Editor,This letter deals with a new second-level-discretization method with higher precision than the traditional first-level-discretization ***,the traditional discretization method utilizes the first-order time derivative information,and it is termed first-level-discretization *** contrast,the new discretization method not only utilizes the first-order time derivative information,but also makes use of the second-order derivative *** combining the new second-level-discretization method with zeroing neural network(ZNN),the second-level-discrete ZNN(SLDZNN)model is proposed to solve dynamic(i.e.,time-variant or time-dependent)linear *** experiments and application to angle-of-arrival(AoA)localization show the effectiveness and superiority of the SLDZNN model.

关键词： method derivative utilize

Bipolar hip arthroplasty using conjoined tendon preserving posterior lateral approach in treatment of displaced femoral neck fractures

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World Journal of Clinical Cases 2024年第6期12卷 1076-1083页

作者： Ting-Xin Yan Sheng-Jie dong Bo Ning yu-Chi Zhao Department of Joint Surgery Yantaishan HospitalYantai 264003Shandong ProvinceChina Department of Joint Surgery Dongying People's HospitalDongying 257091Shandong ProvinceChina

BACKGROUND Hip fractures account for 23.8%of all fractures in patients over the age of 75 *** than half of these patients are older than 80 *** hemiarthroplasty(BHA)was established as an effective management option for these *** approaches can be used for the BHA ***,there is a high risk of postoperative *** conjoined tendon-preserving posterior(CPP)lateral approach was introduced to reduce postoperative dislocation *** To evaluate the effectiveness and safety of the CPP lateral approach for BHA in elderly *** We retrospectively analyzed medical data from 80 patients with displaced femoral neck fractures who underwent *** patients were followed up for at least 1 *** the 80 patients,57(71.3%)were *** time to operation averaged 2.3 d(range:1-5 d).The mean age was 80.5 years(range:67-90 years),and the mean body mass index was 24.9 kg/m^(2)(range:17-36 kg/m^(2)).According to the Garden classification,42.5%of patients were typeⅢand 57.5%of patients were typeⅣ.Uncemented bipolar hip prostheses were used for all *** conjoined tendons,dislocations,and adverse complications during and after surgery were *** The mean postoperative follow-up time was 15.3 months(range:12-18 months).The average surgery time was 52 min(range:40-70 min)with an average blood loss of 120 mL(range:80-320 mL).The transfusion rate was 10%(8 of 80 patients).The gemellus inferior was torn in 4 patients(5%),while it was difficult to identify in 2 patients(2.5%)during *** posterior capsule was punctured by the fractured femoral neck in 3 patients,but the conjoined tendon and the piriformis tendon remained *** patients had stem varus greater than 3 degrees or femoral *** were no patients with stem subsidence more than 5 mm at the last *** postoperative dislocations were observed throughout the follow-up *** significance was found between preoperative an

关键词： Conjoined tendon preserving Bipolar hip arthroplasty Femoral neck fractures Postoperative dislocation Posterolateral approach

A flame-retardant binder with high polysulfide affinity for safe and stable lithium–sulfur batteries

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Science China Chemistry 2024年第3期67卷 1028-1036页

作者： Guowei yu Guofeng Ye Cheng Wang Chenyang Wang Zhaoyun Wang Pu Hu yu Li Xi-Xi Feng Shuang-Jie Tan min Yan Sen Xin Zhitian Liu Hubei Key Laboratory of Plasma Chemistry and Advanced Materials Hubei Engineering Technology Research Center of Optoelectronic and New Energy MaterialsSchool of Materials Science and EngineeringWuhan Institute of TechnologyWuhan 430205China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China CAS Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular SciencesBeijing National Laboratory for Molecular Sciences(BNLMS)Institute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Lithium-sulfur(Li-S) batteries have shown promises for the next-generation, high-energy electrochemical storage, yet are hindered by rapid performance decay due to the polysulfide shuttle in the cathode and safety concerns about potential thermal runaway. To address the above challenges, herein, we show a flame-retardant cathode binder that simultaneously improves the electrochemical stability and safety of batteries. The combination of soft and hard segments in the polymer framework of binders allows high flexibility and mechanical strength for adapting to the drastic volume change during the Li(de)intercalation of the S cathode. The binder contains a large number of polar groups, which show the high affinity to polysulfides so that they help to anchor active S species at the cathode. These polar groups also help to regulate and facilitate the Li-ion transport, promoting the kinetics of polysulfide conversion reaction. The binder contains abundant phosphine oxide groups, which, in the case of battery's thermal runaway, decompose and release PO· radicals to quench the combustion reactions and stop the fire. Consequently, Li-S batteries using the new cathode binder show the improved electrochemical performance, including a low-capacity decay of 0.046% per cycle for 800 cycles at 1 C and favorable rate capabilities of up to 3 C. This work offers new insights on the practical realization of high-energy rechargeable batteries with stable storage electrochemistry and high safety.

关键词： lithium–sulfur battery polymer binder polysulfide affinity flame retardancy

Microstructure and Oxidation Behavior of ZrB_(2)-SiC Ceramics Fabricated by Tape Casting and Reactive Melt Infiltration

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无机材料学报 2024年第8期39卷 955-964页

作者： TAN min CHEN Xiaowu YANG Jinshan ZHANG Xiangyu KAN Yanmei ZHOU Haijun XUE yudong dong Shaoming State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

ZrB_(2)-based ceramics typically necessitate high temperature and pressure for sintering,whereas ZrB_(2)-SiC ceramics can be fabricated at 1500℃using the process of reactive melt infiltration with *** comparison to the conventional preparation method,reactive synthesis allows for the more facile production of ultra-high temperature ceramics with fine particle size and homogeneous *** this work,ZrSi_(2),B4C,and C were used as raw materials to prepare ZrB_(2)-SiC via combination of tape casting and reactive melt infiltration herein referred to as ZBC *** sample of ZrB_(2)-SiC was also prepared using ZrB_(2) and SiC as raw materials through an identical process designated as ZS *** analysis of both ceramic groups revealed smaller and more uniformly distributed particles of the ZrB_(2) phase in ZBC ceramics compared to the larger particles in ZS *** sets of ceramics underwent cyclic oxidation testing in the air at 1600℃for a cumulative duration of 5 cycles,each cycle lasting 2 *** of the oxidation behavior showed that both ZBC ceramics and ZS ceramics developed a glassy SiO_(2)-ZrO_(2) oxide layer on their surfaces during the *** layer severed as a barrier against *** ZBC ceramics,ZrO_(2) is finely distributed in SiO_(2),whereas in ZS ceramics,larger ZrO_(2) particles coexist with glassy SiO_(2).The surface oxide layer of ZBC ceramics maintains a dense structure because the well-dispersed ZrO_(2) increases the viscosity of glassy SiO_(2),preventing its crystallization during the ***,some SiO_(2) in the oxide layer of ZS ceramics may crystallize and form a eutectic with ZrO_(2),leading to the formation of ZrSiO_(4).This leads to cracking of the oxide layer due to differences in thermal expansion coefficients,weakening its barrier *** analysis of the oxidation resistance shows that ZBC ceramics exhibit less increase in oxide layer thickness and mass compared to ZS ceramics,su

关键词： ultra-high temperature ceramic ZrB2-SiC oxidation behavior reactive melt infiltration

Brain abscess from oral microbiota approached by metagenomic next-generation sequencing: A case report and review of literature

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World Journal of Clinical Cases 2024年第3期12卷 616-622页

作者： Xue-min Zhu Chun-Xia dong Lei Xie Hao-Xin Liu Huai-Qiang Hu School of Clinical Medicine Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Department of Neurology the 960th Hospital of People′s Liberation ArmyJinan 250031Shandong ProvinceChina

BACKGROUND Brain abscess is a serious and potentially fatal disease caused primarily by microbial *** progress has been made in the diagnosis and treatment of brain abscesses,the diagnostic timeliness of pathogens needs to be *** SUMMARY We report the case of a 54-year-old male with a brain abscess caused by oral *** patient recovered well after receiving a combination of metagenomic next-generation sequencing(mNGS)-assisted guided medication and *** Therefore,mNGS may be widely applied to identify the pathogenic microor-ganisms of brain abscesses and guide precision medicine.

关键词： Brain abscess Metagenomic next-generation sequencing Periodontitis Oral bacteria Precision medicine Case report

Sepsis one-hour bundle management combined with psychological intervention on negative emotion and sleep quality in patients with sepsis

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World Journal of Psychiatry 2024年第2期14卷 266-275页

作者： ming Xia Guang-Yan dong Shi-Chao Zhu Huan-min Xing Li-ming Li Department of Intensive Care Unit Henan Provincial Key Medicine Laboratory of NursingHenan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou 450003Henan ProvinceChina Department of Nursing Henan Provincial Key Medicine Laboratory of NursingHenan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou 450003Henan ProvinceChina

BACKGROUND Sepsis is a serious infectious disease caused by various systemic inflammatory responses and is ultimately *** usually experience depression and anxiety,which affect their sleep quality and post-traumatic growth *** To investigate the effects of sepsis,a one-hour bundle(H1B)management was combined with psychological intervention in patients with *** This retrospective analysis included 300 patients with sepsis who were admitted to Henan Provincial People’s Hospital between June 2022 and June *** to different intervention methods,the participants were divided into a simple group(SG,n=150)and combined group(CG,n=150).H1B management was used in the SG and H1B management combined with psychological intervention was used in the *** changes of negative emotion,sleep quality and post-traumatic growth and prognosis were compared between the two groups before(T0)and after(T1)*** After intervention(T1),the scores of the Hamilton Anxiety scale and Hamilton Depression scale in the CG were significantly lower than those in the SG(P<0.001).Sleep time,sleep quality,sleep efficiency,daytime dysfunction,sleep disturbance dimension score,and the total score in the CG were significantly lower than those in the SG(P<0.001).The appreciation of life,mental changes,relationship with others,personal strength dimension score,and total score of the CG were significantly higher than those of the SG(P<0.001).The scores for mental health,general health status,physiological function,emotional function,physical pain,social function,energy,and physiological function in the CG were significantly higher than those in the SG(P<0.001).The mechanical ventilation time,intensive care unit stay time,and 28-d mortality of the CG were significantly lower than those of the SG(P<0.05).CONCLUSION H1B management combined with psychological intervention can effectively alleviate the negative emotions of patients with sepsis and inc

关键词： Cluster management Psychological intervention Sepsis Negative emotions Sleep quality Post-traumatic growth