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Synthesis and characterization of acetylated sept-D-glucopyranose carbamate as an oligosaccharide donor

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Chinese Chemical Letters 2014年第1期25卷 134-136页

作者： Chang-Ming Lian Li-Ping Jiang dong-liang liu Key Laboratory of Science & Technology of Eco-Textile Ministry of EducationCollege of ChemistryChemical Engineering & BiotechnologyDonghua University

An oligosaccharide donor, acetylated sept-o-glucopyranose tetradecyl carbamate, was designed and synthesized. This compound could be easily linked to hydroxyl-containing compounds through an Oglycosidic bond. Characte... 详细信息

关键词： Oligosaccharide donor Carbamate β-Cyelodextrin Acidic cleavage Characterization

Radiation construction and excellent performances of Ag NPs/TiO_(2)/PEG/PVP multifunctional aerogel:Adsorption-photocatalytic degradation,photosensitive antibacterial and cytotoxicity

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Journal of Materiomics 2024年第3期10卷 585-593页

作者： Jin-Yu Yang dong-liang liu Yue-Sheng Li Xiao-Jie Yang Yi liu School of Nuclear Technology and Chemistry&Biology/Hubei Key Laboratory of Radiation Chemistry and Functional Materials Hubei University of Science and TechnologyXianning437100HubeiChina Key Laboratory of Coal Conversion and New Carbon Materials of Hubei Province School of Chemistry and Chemical EngineeringWuhan University of Science and TechnologyWuhan437100HubeiChina College of Chemistry and Chemical Engineering Tiangong UniversityTianjin300387China

A cutting-edge method known as photocatalytic antibacterial technology can effectively eliminate drug-resistant bacterial strains and boast a wide-ranging antimicrobial *** the study,a novel Ag NPs/TiO_(2)/PEG/PVP(ATPP)aerogel photocatalyst was synthesized by an electron beam in-situ radiation method using polyethylene glycol(PEG),polyvinylpyrrolidone(PVP),AgNO_(3),and TiO_(2)as raw *** was characterized by X-ray diffraction spectroscopy(XRD),X-ray photoelectron spectroscopy(XPS)and solid ultraviolet diffuse reflectance spectroscopy(UV-Vis DRS).The results demonstrated that silver ions were reduced to silver nanoparticles by electron beam radiation *** the same time,the doping of silver nanoparticles(Ag NPs)enhanced visible-light *** degradation rate of methylene blue(MB)on 5%(in mass)ATPP could reach 81%under visible light for 180 *** coli(***)and Staphylococcus aureus(***)were used as model bacteria to explore the antimi-crobial properties of ATPP by zone of the inhibition method,plate counting method and live/dead bacterial *** antibacterial experiments showed that the antibacterial effect of ATPP was ***,MTT assay and Hoechst33342/PI double staining were used to prove that the composite had good *** aerogel photocatalytic material has the potential to decrease microbial presence in both medical and environmental settings,making it a valuable tool for such applications.

关键词： Ag NPs/TiO_(2)/PEG/PVP aerogel Electron beam radiation Adsorption-photocatalytic Photosensitive antibacterial Cytotoxicity

Dish Verification Antenna China for the SKA:design, verification and status

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Research in Astronomy and Astrophysics 2019年第6期19卷 97-108页

作者： Biao Du Yang Wu Yuan-Peng Zheng Xiao-Ming Chai Guo-Xi liu Hai-dong Wang Yi-Fan Zhang Sheng-Hua Yu Bin liu Ye-Zhao Yu Hong-Wei Xi Long Chen Lei Yu dong-liang liu Cheng-Jin Jin Bo Peng The 54^th Research Institute of CETC Shijiazhuang 050081 China Joint Laboratory of Radio Astronomy Technology Beijing 100101 China National Astronomical Observatories Chinese Academy of Sciences Beijing 100101 China

The Square Kilometre Array(SKA) will be the world’s largest synthesis radio telescope, which is designed to answer major scientific questions such as those relating to the cosmic origin and fundamental forces in the universe. With the SKA entering into the phase of pre-construction, more than 100 institutes in about 20 countries including China have been involved in the associated key technology *** Dish Verification Antenna China(DVA-C) is a concept prototype which has been built to meet the requirements of the SKA’s scientific goals. It utilizes a unique skin-and-rib structure with single-piece panel reflectors. This paper presents details on the design and measured performances of DVA-C, as well as the preliminary observational results. Current applications of the DVA-C are also introduced.

关键词： Square Kilometre Array radio telescope dish-single-piece panel

Isolated traumatic gallbladder injury: A case report

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2639-2645页

作者： dong-liang liu Jun-Yong Pan Tian-Cong Huang Cheng-Zong Li Wen-Du Feng Gao-Xiong Wang Department of Hepatobiliary&Pancreatic Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina Department of Hospital Administration Office Quanzhou Women's and Children's HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Isolated gallbladder injury(GI)(IGI)directly induced by abdominal trauma is ***,indications,and imaging examinations of IGI are frequently non-specific,posing tremendous diagnostic challenges,which are simple to overlook and may have severe *** doctors'understanding of gallbladder injury(GI)facilitates early detection and decreases the likelihood of severe consequences,including *** SUMMARY We report a case of IGI caused by blunt violence(after falling from three meters with the umbilicus as the stress point)and performed laparoscopic repair of the gallbladder rupture,which helps clinicians understand IGI and reduce the severe consequences of delayed *** extensive medical history and dynamic abdominal ultrasound evaluation,doctors can identify GI early and begin surgery,thereby decreasing the devastating repercussions of delayed *** This article aims to improve clinicians'understanding of IGI and propose a method for the diagnosis and treatment of GI.

关键词： Isolated gallbladder injury Blunt abdominal trauma Gall bladder trauma Case report

Plasma-Enhanced Atomic Layer Deposition of Amorphous Ga_(2)O_(3) for Solar-Blind Photodetection

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Journal of Electronic Science and Technology 2022年第4期20卷 331-344页

作者： Ze-Yu Fan Min-Ji Yang Bo-Yu Fan Andraz Mavric Nadiia Pastukhova Matjaz Valant Bo-Lin Li Kuang Feng dong-liang liu Guang-Wei Deng Qiang Zhou Yan-Bo Li Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054 Materials Research Laboratory University of Nova GoricaNova Gorica SI-5000 Yangtza Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001

Wide-bandgap gallium oxide(Ga_(2)O_(3))is one of the most promising semiconductor materials for solar-blind(200 nm to 280 nm)*** its amorphous form,amorphous gallium oxide(a-Ga_(2)O_(3))maintains its intrinsic optoelectronic properties while can be prepared at a low growth temperature,thus it is compatible with Si integrated circuits(ICs)***,the a-Ga_(2)O_(3) film is directly deposited on pre-fabricated Au interdigital electrodes by plasma enhanced atomic layer deposition(PE-ALD)at a growth temperature of 250°*** stoichiometric a-Ga_(2)O_(3) thin film with a low defect density is achieved owing to the mild PE-ALD *** a result,the fabricated Au/a-Ga_(2)O_(3)/Au photodetector shows a fast time response,high responsivity,and excellent wavelength selectivity for solar-blind ***,an ultra-thin MgO layer is deposited by PE-ALD to passivate the Au/a-Ga_(2)O_(3)/Au interface,resulting in the responsivity of 788 A/W(under 254 nm at 10 V),a 250-nm-to-400-nm rejection ratio of 9.2×10^(3),and the rise time and the decay time of 32 ms and 6 ms,*** results demonstrate that the a-Ga_(2)O_(3) film grown by PE-ALD is a promising candidate for high-performance solar-blind photodetection and potentially can be integrated with Si ICs for commercial production.

关键词： Amorphous gallium oxide(a-Ga_(2)O_(3)) passivation layer plasma enhanced atomic layer deposition(PE-ALD) responsivity solar-blind photodetector

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

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Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： Jiayi Wang Mengke Zhao dong Fu Meina Wang Chao Han Zhongyue Lv liang Wang Jing liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

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一种新的预条件伴随状态法初至波走时层析

地球物理学报 2017年第10期60卷 3934-3941页

作者：李勇德董良国刘玉柱同济大学海洋地质国家重点实验室上海200092

伴随状态法初至波走时层析是基于最优化理论的一种层析成像方法,该方法不必进行射线追踪,用两次正演的计算量便可以获得梯度,具有计算效率高、内存占用小等优点,但是其一阶方向在初始模型或观测孔径不理想的情况下往往无法获得正确的反... 详细信息

伴随状态法初至波走时层析是基于最优化理论的一种层析成像方法,该方法不必进行射线追踪,用两次正演的计算量便可以获得梯度,具有计算效率高、内存占用小等优点,但是其一阶方向在初始模型或观测孔径不理想的情况下往往无法获得正确的反演结果,而二阶方向的实现又比较困难且费时.在伴随状态法的基础上,将走时差替换为定值,再次进行反演,便可以得到类似于射线密度的矩阵,用该矩阵的逆可以方便地进行预条件.基于该方法,本文提出了一种简单易行的预条件伴随状态法初至波走时层析的实现方法.理论模型和实际资料处理结果都表明,该方法既保留了伴随状态法初至波走时层析的优点,又可以克服一阶方向的局限,获得良好的反演效果.

关键词：地震层析成像伴随状态法初至波走时近地表速度预条件

Correlations of the expression of Cx43,SCFFBXW7,p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in colon cancer tissues

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 207-213页

作者： Rong-Gang Luan Ming-Da liu Zi-Feng Deng Cong-Lan Lu Mei-Ling Yu Ming-Yu Zhang Rong liu Ran An You-liang Yao dong-Bei Guo Yong-Xing Zhang Lei Zhao Department of Gastrointestinal Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen 361102Fujian ProvinceChina Trauma Surgery Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina Department of Orthopaedics Air Force Hospital of Eastern TheaterAnhui Medical UniversityNanjing 230032Jiangsu ProvinceChina

BACKGROUND Previous cellular studies have demonstrated that elevated expression of Cx43 promotes the degradation of cyclin E1 and inhibits cell proliferation through ***,reduced expression results in a loss of this capacity to facilitate cyclin E *** ubiquitination and degradation of cyclin E1 may be associated with phosphorylation at specific sites on the protein,with Cx43 potentially enhancing this process by facilitating the phosphorylation of these critical *** To investigate the correlation between expression of Cx43,SKP1/Cullin1/F-box(SCF)FBXW7,p-cyclin E1(ser73,thr77,thr395)and clinicopathological indexes in colon *** Expression levels of Cx43,SCFFBXW7,p-cyclin E1(ser73,thr77,thr395)in 38 clinical colon cancer samples were detected by immunohistochemistry and were analyzed by statistical methods to discuss their *** Positive rate of Cx43,SCFFBXW7,p-cyclin E1(Ser73),p-cyclin E1(Thr77)and p-cyclin E1(Thr395)in detected samples were 76.32%,76.32%,65.79%,5.26%and 55.26%*** expressions of these proteins were not related to the tissue type,degree of tissue differentiation or lymph node ***43 and SCFFBXW7(r=0.749),p-cyclin E1(Ser73)(r=0.667)and p-cyclin E1(Thr395)(r=0.457),SCFFBXW7 and p-cyclin E1(Ser73)(r=0.703)and p-cyclin E1(Thr395)(0.415)were correlated in colon cancer(P<0.05),and expressions of the above proteins were positively correlated in colon *** Cx43 may facilitate the phosphorylation of cyclin E1 at the Ser73 and Thr195 sites through its interaction with SCFFBXW7,thereby influencing the ubiquitination and degradation of cyclin E1.

关键词： Colon cancer Cx43 SCFFBXW7 Phosphorylation of cyclin E1 Sites of cyclin E1 Correlation analysis

四边形折流式膜生物流化床内填料浓度及液相流场特性研究

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环境科学学报 2017年第11期37卷 4139-4149页

作者：董亮曾涛刘少北王勇张长练四川理工学院过程装备与控制工程四川省高校重点实验室自贡643000

针对研究开发的四边形折流式膜生物流化床,构建了气、固、液三相流可视化平台,应用取样法和激光粒子图像测速(PIV)技术剖析了不同进水流量和曝气强度组合对流化床内的填料浓度及液相流场特性的影响.结果表明,折流板上部形成的曝气死区,... 详细信息

针对研究开发的四边形折流式膜生物流化床,构建了气、固、液三相流可视化平台,应用取样法和激光粒子图像测速(PIV)技术剖析了不同进水流量和曝气强度组合对流化床内的填料浓度及液相流场特性的影响.结果表明,折流板上部形成的曝气死区,提高了升流区的填料浓度;折流板和导流锥形成的进水角度使流场冲击反应器底部的填料,提高了在低曝气强度下流化床的填料浓度,在实际运行过程可降低曝气能耗;四边形折流式膜生物流化床的结构特点导致填料与膜组件相互碰撞的概率增大,强化了膜污染的控制.曝气强度和进水流量的变化改变了液相的轴向返混强度和剪切力,进而改变了填料浓度,使气、固、液三相冲刷膜组件的作用增大,最终影响膜面传质系数和浓差极化边界层厚度,降低了膜污染.通过流化床结构的改变提高填料浓度和改善流场特性,为高浓度有机废水好氧生物的处理提供了一个研究方向.

关键词：粒子图像测速(PIV) 生物流化床湍动能气固液三相流小尺度涡