检索结果-南通市图书馆

Long Term Perinatal Deltamethrin Exposure Alters Electrophysiological Properties of Embryonic Ventricular Cardiomyocyte

引用

Current Medical Science 2019年第1期39卷 21-27页

作者： Hong-yan LUO Jacob Masika Xiu-wen Guan Li NIE dong-hui ao Yu QI Rui SHI Jurgen Hescheler Ying ZENG Department of Physiology Hubei Key Laboratory of Drug Target Research and Pharmacodynamic EvaluationSchool of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Medical Physiology Faculty of Health SciencesEverton UniversityNjoro 535-20115Kenya The People's Hospital of Huangpi District Wuhan 430300China College of Pharmacy Wuhan Institute of BioengineeringWuhan 430415China Istitute of Physiology University of CologneCologne 50931Germany Department of Pharmaceutics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Increased use of pyrethroids and the exposure to pyrethroids for pregnant women and children have raised the concerns over the potential effect of pyrethroids on developmental cardiotoxicity and other *** purpose of this study was to investigate whether long tenn peri natal deltamethrin exposure altered embryonic cardiac electrophysiology in *** mice were administered with 0 or 3 mg/kg of deltamethrin by gavage daily from gestational day(gd)10.5 to gd *** cell patch-clamp technique was used in electrophysiological study,and real time RT-PCR was applied to analyze the molecular changes for the electrophysiological *** exposure resulted in increased mortality of pregnant mice and decreased viability of ***,deltamethrin slowed the maximum depolarization velocity(Vmax),prolonged the action potential duration(APD)and depolarized the maximuin diastolic potential(MDP)of embryonic ***,perinatal deltamethrin exposure decreased the mRNA expression of Na^+channel regulatory subunit Navpl,inward rectifier K^+channel subunit Kir2.1,and delayed rectifier K^+channel subunit MERG while the L-type Ca^2+channel subunit,Cavl.2 expression was *** the contraiy,deltamethrin administration did not significantly alter the regulation ofβ-adrenergic or muscarinic receptor on embryonic *** conclusion,deltamethrin exposure at perinatal stage significantly alters mRNA expression of embryonic cardiac ion channels and therefore influences embryonic cardiac electrophysiological *** highlights the need to understand the persistent effects of pyrethroid exposure on cardiac function during embryonic development due to potential for cardiac arrhythmogenicity.

关键词： pyrethroid deltamethrin embryonic cardiomyocytes action potential developmental cardiotoxicity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

C@Ag core‒shell structure as lubricating additives towards high efficient lubrication

引用

Friction 2024年第9期12卷 1991-2003页

作者： dong ao Xiaoqiang FAN Minhao ZHU Key Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China Tribology Research Institute School of Mechanical EngineeringSouthwest Jiaotong UniversityChengdu 610031China

Efficient cooperative lubrication can be achieved via the introduction of core‒shell structure lubricant additives with hard core and soft shell,for obtaining the expected anti-wear performance from the structural changes in the friction *** this study,C@Ag microspheres with a core‒shell structure were prepared by the redox method with carbon spheres as the core and Ag nanoparticles as the *** tribological behaviors as base oil(G1830)additive with different concentrations were investigated in *** with base oil,the addition of C@Ag particles at 0.5 wt%can reduce the coefficient of friction(COF)and wear volume(Wv)up to 15.5%and 88%,*** importantly,C@Ag particles provide superior lubrication performance to single additive(like carbon sphere(CS)and Ag nanoparticle).C@Ag core‒shell particles contribute to the formation of tribo-film by melt bonding of flexible Ag and carbon sphere(CS)toward excellent self-repair performance and high-efficiency ***,core‒shell structural nanoparticles with hard-core and soft-shell hold bright future for high-performance lubrication application.

关键词： C@Ag microspheres tribo-film self-repair performance high-efficiency lubrication

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

减氮及有机肥替代对旱地冬小麦干物质积累、转运、分配和产量的影响

引用

作物学报 2025年第1期51卷 207-220页

作者：张军胡川周起晖任开明董誓言刘傲寒吴金芝黄明李友军河南科技大学农学院河南洛阳471023 商洛学院生物医药与食品工程学院陕西商洛726000

探究减氮及有机肥替代对旱地冬小麦产量形成和经济效益的影响,为实施化肥减量和有机肥替代提供理论和技术依据。2021-2023年度,基于2019年开始设置在黄土高原和黄淮海平原交汇处典型旱地冬小麦产区(河南洛宁和河南孟津)的定位试验,研究... 详细信息

探究减氮及有机肥替代对旱地冬小麦产量形成和经济效益的影响,为实施化肥减量和有机肥替代提供理论和技术依据。2021-2023年度,基于2019年开始设置在黄土高原和黄淮海平原交汇处典型旱地冬小麦产区(河南洛宁和河南孟津)的定位试验,研究了冬小麦干物质积累转运分配特性、氮肥干物质生产效率、产量及其构成要素和经济效益。试验设置不施氮肥(NN)、农户施氮(FN)、基于FN减氮20%(RN)和RN基础上20%氮肥用有机肥替代(OSN)4个处理。结果表明:(1)与FN相比,RN处理降低了小麦拔节期、开花期和成熟期的干物质积累量、花前干物质转运量以及成熟期茎鞘、穂轴+颖壳和籽粒的干物质分配量,但对籽粒产量无显著影响。(2)与FN和RN相比, OSN处理提高了各生育阶段的氮肥干物质生产效率,从而增加了拔节期、开花期、成熟期的干物质积累量,而且提高了花前干物质转运量、花后干物质积累量、花后干物质积累量对籽粒的贡献率,进而使成熟期地上部各器官的干物质分配量均得到显著提高,最终使籽粒产量分别显著增加15.03%和17.12%,经济效益增加3.84%和4.23%。(3)小麦产量与花前干物质转运量、花后干物质积累量和花后干物质积累量对籽粒的贡献率呈极显著正相关,与花前干物质转运量对籽粒的贡献率呈极显著负相关。综上,在雨养条件下,小麦季施氮量为172kghm^(–2) (夏休闲-冬小麦)和192kg hm^(–2) (夏玉米-冬小麦)的基础上,OSN处理提高了氮肥干物质生产效率,增加各生育时期的干物质积累量,其花前干物质转运量和花后干物质积累量的协同增加使其获得了最高产量,实现增产增收,适宜在产量水平为5000kghm^(–2)的雨养旱地冬小麦高产栽培中应用。

关键词：旱地冬小麦减氮有机肥替代干物质积累转运产量经济效益

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Poly(1,8-octanediol citrate)/bioactive glass composite with improved mechanical performance and bioactivity for bone regeneration

引用

Chinese Chemical Letters 2017年第11期28卷 2116-2120页

作者： hui-hui Ren hui-Yu Zhao Yang Cui Xiang ao Ai-Ling Li Zhong-Min Zhang dong Qiu Beijing National Laboratory for Molecular Sciences State Key Laboratory of Polymer Physics and Chemistry CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100190 China Department of Orthopedics The Third Affiliated Hospital of Southern Medical University Guangzhou 510665 China

Poly（1,8-octanediol-co-citrate）（POC） represents a new promising biocompatible and biodegradable polyester that has been extensively investigated for soft tissue engineering. However, the poor mechanical performance and poor bioactivity limit its application in bone regeneration. In this study, a series of POC/bioactive glasses （BG） composites were developed using 45S5 Bioglass^Θ and a phytic acid- derived bioactive glass （referred as PSC）. The results indicated that calcium in BG could enhance the crosslinking of the POC/BG composites by forming calcium dicarboxylate bridges and thus improve their mechanical performances. When PSC were used, the composites exhibited significantly better mechanical properties compared to composites with 45S5 Bioglass^Θ. For example, by incorporating 70wt% PSC, the compressive strength of POC/PSC composites could be improved to approximately 50 MPa and modulus 1.3-h 0.1 GPa. Furthermore, all these POC/PSC composites showed good in vitro bioactivity and cellular biocompatibility. Histology results in femoral condyle defects of Sprague-Dawley rats indicated that the POC/PSC samples integrated well with surrounding tissues and stimulated bone regeneration. The improved mechanical properties and bioactivity of POC/PSC composites make them promising for potential application in bone regeneration.

关键词： Bioactive glasses Poly(1 8-octanediol-co-citrate) Composites Mechanical properties Bioactivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simulation and experimental investigation on a dynamic lateral flow mode in trepanning electrochemical machining

引用

Chinese Journal of Aeronautics 2017年第4期30卷 1624-1630页

作者： dong ZHU Zhouzhi GU Tingyu XUE ao LIU College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

An appropriate flow mode of electrolyte has a positive effect on process efficiency, surface roughness, and machining accuracy in the electrochemical machining（ECM） process. In this study, a new dynamic lateral flow mode, in which the electrolyte flows from the leading edge to the trailing edge, was proposed in trepanning ECM of a diffuser. Then a numerical model of the channel was set up and simulated by using computational fluid dynamics software. The result showed that the distribution of the flow field was comparatively uniform in the inter-electrode gap. Furthermore, a fixture was designed to realize this new flow mode and then corresponding experiments were carried out. The experimental results illustrated that the feeding rate of the cathode reached 2 mm/min, the best taper angle was about 0.4°, and the best surface roughness was up to Ra= 0.115 lm. It reflects that this flow mode is suitable and effective, and can also be applied to machining other complex structures in trepanning ECM.

关键词： Diffuser Electrochemical machining Electrolyte Experiment Flow

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Global Mg/Si and Al/Si Distributions on the Lunar Surface Derived from Chang'E-2 X-ray Spectrometer

引用

Research in Astronomy and Astrophysics 2016年第1期16卷 31-38页

作者： Wu-dong dong Xiao-Ping Zhang Meng-Hua Zhu ao-ao Xu Ze-Sheng Tang Lunar and Planetary Science Laboratory Macao University of Science and Technology

The technique of X-ray fluorescence remote sensing plays a significant role in research related to the chemical compositions of the Moon. Here we describe the data analysis method for China＇s Chang＇E-2 X-ray spectrometer in detail and present the preliminary results about the first global Mg/Si and Al/Si maps of the lunar surface. Our results show that the distributions of Mg/Si and Al/Si correlate well with terrains on the Moon. The higher Mg/Si ratio corresponds to the mare regions while the lower value corresponds to the highland terrains. The map of the Al/Si ratio shows a reversed distribution compared with the map of the Mg/Si ratio.

关键词： Moon -- planets and satellites: composition -- techniques: spectroscopic -- X-rays: general

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficient piezo-assisted near-infrared-light-driven Cr(Ⅵ)reduction over Bi_(2)S_(3) nanowires transformed from ultrathin Bi_(2)WO_(6) nanosheets

引用

Rare Metals 2024年第9期43卷 4333-4343页

作者： Qiang Zhang Yuan-Hao Cheng Wei Liu hui-Nan Che Yan-hui ao Key Laboratory of Integrated Regulation and Resource Development On Shallow Lakes Ministry of EducationCollege of EnvironmentHohai UniversityNanjing 210098China

The utilization of piezo-photocatalytic technol ogy for environmental remediation under full spectrum solar light is promising but still ***,one dimensional Bi_(2)S_(3)nanowires,which can utilize both mechanical energy and near-infrared(NIR)light to remov hexavalent chromium(Cr(Ⅵ))efficiently,were synthe sized by a restrained growth *** reaction rat constants of Cr(Ⅵ)reduction in piezo-photocatalyti process under NIR(800–2500 nm)reached 0.334 min^(-1)which were 3.2 and 12.4 times as that of single piezo and photocatalytic *** formation of polarized electri fields and one-dimensional structure allow ultrafast sepa ration of charge carriers,thereby promoting the catalyti ***,due to the strong penetrability o NIR light,the piezo-photocatalysis performance in turbid solutions under NIR light(0.188 min^(-1))was even com parable to that under visible light(0.186 min^(-1)).Thi study provides a new concept on the development of piezo photocatalytic technology for environmental remediation by utilization of NIR light and natural mechanical energy.

关键词： Piezo-photocatalysis NIR light Bi_(2)S_(3)nanowires Cr(Ⅵ)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ultrafast photocatalytic degradation of nitenpyram by 2D ultrathin Bi2WO6:mechanism,pathways and environmental factors

引用

Rare Metals 2022年第7期41卷 2439-2452页

作者： Yuan-Hao Cheng Juan Chen hui-Nan Che Yan-hui ao Bin Liu Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes of Ministry of Education College of EnvironmentHohai UniversityNanjing 210098China School of Chemical and Biomedical Engineering Nanyang Technological UniversitySingapore 637459Singapore

As a common insecticide,nitenpyram(NTP)seriously threatens the human health and environmental *** this work,a visible-light-responsive photocata-lyst two-dimensional(2D)Bi_(2)WO_(6) was synthesized and applied to degrade *** with bulk Bi_(2)WO_(6),the 2D Bi_(2)WO_(6)exhibits better photocatalytic performance for NTP degradation under visible-light *** enhanced activity can be ascribed to the unique 2D struc-ture which would induce to higher efficiency of carrier ***,hole(h+)plays a major role(and·O^(2-))in the degradation of *** on the interme-diates detected by high-performance liquid chromatogra-phy-mass spectrometry(HPLC-MS),the degradation pathway of NTP was *** addition,the influence of typical environmental factors(pH,water matrix,inorganic cations and common anions)on the degradation of NTP was also *** work not only helps people to understand the degradation of pesticides in actual water bodies,but also provides reference for the subsequent treatment of agricultural wastewater.

关键词： Photocatalysis Two-dimensional(2D)Bi_(2)WO_(6) Nitenpyram Degradation pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A robust and transparent nanosilica-filled silicone rubber coating with synergistically enhanced mechanical properties and barrier performance

引用

Journal of Materials Science & Technology 2023年第20期151卷 219-226页

作者： Shiyao Du hui Yan Zihe Liu ao Tang Ying Li Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Shenyang National Laboratory for Materials Science Northeastern UniversityShenyang 110819China

Implantable electronic devices(IEDs)are widely used by human beings to achieve medical treatment and diagnosis ***,ideal encapsulation of IEDs is still far from perfect as full prevention of body fluid diffusion into the coating remains ***,we develop a high-performance composite coating for IED encapsulation by introducing SiO_(2) nanoparticles into silicone rubber,which synergistically enhances mechanical properties and improves barrier *** fabricating composite coatings with different nanosilica contents,3%nanosilica is proved to be an optimal additive content with an excellent combination of improved fracture strength(from 2.5 MPa to 4.5 MPa),increased coating resistance(from 10^(4) to 10^(9) cm^(2))and ideal coating *** and electrochemical characterizations subsequently confirm substantially enhanced mechanical properties and barrier performance of the composite coating,which effectively resist crack propagation and impede penetrations of water and chloride ions through the *** calculations further uncover that modified SiO_(2) particles with enriched methyl groups endow a strong bridging effect to interact with silicone rubber monomer,which,together with anti-agglomeration property of methyl groups,contributes to a pronounced improvement in mechanical performance of nanosilica-filled silicone *** from the enhanced mechanical and barrier properties,the as-fabricated nanosilica-filled silicone rubber demonstrates superior protection for the encapsulated circuits with a significantly improved lifetime(709.1 h)compared to that of circuits coated by pure silicone rubber(472.8 h)and bare circuit boards(1 h),which offers great values for packaging material design in future IED encapsulation.

关键词： Organic coatings Implantable electronic devices Nanosilica DFT calculation Mechanical property

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Back-Stepping Control for Flexible Air-Breathing Hypersonic Vehicles Based on Uncertainty and Disturbance Estimator

引用

Journal of Beijing Institute of Technology 2020年第4期29卷 504-513页

作者： Lin Cao dong Zhang ao Zhang System Engineering Institute of Sichuan Aerospace Chengdu 610100China College of Astronautics Northwestern Polytechnical UniversityXi’an 710072China

A theoretical framework of nonlinear flight control for a flexible air-breathing hypersonic vehicle(FAHV)is proposed in this *** order to suppress the system uncertainty and external disturbance,an uncertainty and disturbance estimator(UDE)based back-stepping control strategy is designed for a dynamic state-feedback controller to provide stable velocity and altitude ***,the longitudinal dynamics of FAHV is simplified into a closure loop form with lumped uncertainty and *** the UDE is applied to estimate the lumped uncertainty and disturbance for the purpose of control input *** a nonlinear tracking differentiator is introduced to solve the problem of“explosion of term”in the back-stepping *** stability of the UDE-based control strategy is proved by using Lyapunov stability ***,simulation results are presented to demonstrate the capacity of the proposed control strategy.

关键词： flexible air-breathing hypersonic vehicle(FAHV) uncertainty and disturbance estimator(UDE) back-stepping control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：