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Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint:A Retrospective Analysis

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当代医学科学（英文） 2024年第4期44卷 741-747页

作者： Su-guo WANG Yong-gang WANG Guo-wei QIAN Li-na TANG Xin ZHOU dong-dong cheng Chen-liang ZHOU Qing-cheng YANG Zan SHEN Gao-zhong HUANG Hong-tao LI Department of General Medicine Shenzhen Third People's Hospital Shenzhen 518112China Department of VIP Clinic Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China Department of Oncology Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China Cancer Research Institute of Jilin University the First Hospital of Jilin UniversityChangchun 130021China Department of Orthopedics Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China Department of VIP Clinic Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China

Objective:To investigate the serum lipid profiles of patients with localized osteosarcoma around the knee joint before and after neoadjuvant ***:After retrospectively screening the data of 742 patients between January 2007 and July 2020,50 patients aged 13 to 39 years with Enneking stage Ⅱ disease were included in the *** lipid levels,including total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),lipoprotein-α[Lp(a)],and apolipoprotein Al,B,and E(ApoA1,ApoB,and ApoE),and clinicopathological characteristics were collected before and after neoadjuvant ***:The mean levels of TC,TG,and ApoB were significantly increased following neoadjuvant chemotherapy(16％,38％,and 20％,respectively,*** values;P＜0.01).The mean levels of LDL-C and ApoE were also 19％and 16％higher,respectively(P＜0.05).No correlation was found between the pretreatment lipid profile and the histologic response to *** increase in Lp(a)was strongly correlated with the Ki-67 index(R=0.31,P=0.023).Moreover,a trend toward longer disease-free survival(DFS)was observed in patients with decreased TG and increased LDL-C following chemotherapy,although this difference was not statistically significant(P=0.23 and P=0.24,respectively).Conclusion:Significant elevations in serum lipids were observed after neoadjuvant chemotherapy in patients with localized *** was no prognostic significance of pretreatment serum lipid levels on histologic response to neoadjuvant *** scale of increase in serum Lp(a)might have a potential prognostic role in *** with increased LDL-C or reduced TG after chemotherapy seem to exhibit a trend toward favorable DFS.

关键词： neoadjuvant chemotherapy osteosarcoma serum lipids

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Regularization of mathematical model for chip flow angle catastrophe

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Advances in Manufacturing 2021年第4期9卷 568-579页

作者： Shao-Nan Zhang dong-dong cheng Liang-Shan Xiong School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China

The chip flow angle(CFA)catastrophe in double-edged cutting results in a significant reduction in the cutting force,which can benefit the ***,established potential functions(i.e.,cutting power calculation functions)of mathematical models for the CFA catastrophe are presented in the form of transcendental functions with two control parameters and one state parameter,which are extremely complex.A method is proposed herein to realize the regularization of the potential functions and establish mathematical models in a standard form and with complete content for the CFA *** this method,the potential function of the CFA catastrophe is expanded into a k-order Taylor polynomial at each midpoint of N end-to-end equally partitioned intervals of the state parameter using the Taylor function provided in *** potential function after piecewise Taylor expansion is transformed into the same form as the potential function of the standard cusp catastrophe model by truncating the first five terms of the Taylor polynomial and eliminating the third-order term of the state parameter with elementary ***,the regularization of potential function is ***,the regularization of equilibrium surface and bifurcation set can be realized based on the conclusions of the catastrophe *** errors of the potential function,equilibrium surface,and bifurcation set are defined to evaluate the effectiveness of this regularization *** problem of calculating regularization errors is regarded as an optimization ***‘‘simulannealbnd’’function provided in MATLAB is used to solve the *** the proposed method,the regularization of a mathematical model for the CFA catastrophe established by the predecessor is completed;a mathematical model(i.e.,standard cusp catastrophe model)in a standard form and with complete content for the CFA catastrophe is established;and the corresponding regularization errors

关键词： Chip flow angle(CFA)catastrophe Mathematical model Regularization Potential function Catastrophe theory Cusp catastrophe model

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An Ideal Assortative Network and Synchronization

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Communications in Theoretical Physics 2007年第1期47卷 186-192页

作者： dong cheng-dong LIU Zeng-Rong Department of Applied Mathematics Shanghai University of Finance and Economics Shanghai 200433 China Institute of Systems Biology Shanghai University Shanghai 200444 China

This paper proposes a novel complex network with assortative property based on multi-center networks. The average path length and clustering coefficient of the network are calculated, and the impact on the network topology is investigated. A simple dynamic system established on the proposed network is used to analyze how the assortative property of the network affects synchronization.

关键词： complex network assortative property average path length clustering coefficient synchronization

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Swarm Intelligence Research:From Bio-inspired Single-population Swarm Intelligence to Human-machine Hybrid Swarm Intelligence

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Machine Intelligence Research 2023年第1期20卷 121-144页

作者： Guo-Yin Wang dong-dong cheng De-You Xia Hai-Huan Jiang Chongqing Key Laboratory of Computational Intelligence Chongqing University of Posts and TelecommunicationsChongqing 400065China College of Big Data and Intelligent Engineering Yangtze Normal UniversityChongqing 408100China

Swarm intelligence has become a hot research field of artificial *** the importance of swarm intelli-gence for the future development of artificial intelligence,we discuss and analyze swarm intelligence from a broader and deeper *** a broader sense,we are talking about not only bio-inspired swarm intelligence,but also human-machine hybrid swarm *** a deeper sense,we discuss the research using a three-layer hierarchy:in the first layer,we divide the research of swarm intelli-gence into bio-inspired swarm intelligence and human-machine hybrid swarm intelligence;in the second layer,the bio-inspired swarm intelligence is divided into single-population swarm intelligence and multi-population swarm intelligence;and in the third layer,we re-view single-population,multi-population and human-machine hybrid models from different ***-population swarm intel-ligence is inspired by biological *** further solve complex optimization problems,researchers have made preliminary explor-ations in multi-population swarm ***,it is difficult for bio-inspired swarm intelligence to realize dynamic cognitive in-telligent behavior that meets the needs of human *** have introduced human intelligence into computing systems and proposed human-machine hybrid swarm *** addition to single-population swarm intelligence,we thoroughly review multi-population and human-machine hybrid swarm intelligence in this *** also discuss the applications of swarm intelligence in optimization,big data analysis,unmanned systems and other ***,we discuss future research directions and key issues to be studied in swarm intelligence.

关键词： Swarm intelligence single-population multi-population human-machine hybrid multi-granularity

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Wideband Millimeter Wave Antenna with Cavity Backed Slotted Patch and Magneto-Electric Dipole

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Chinese Journal of Electronics 2024年第5期33卷 1234-1244页

作者： Yang cheng Yuandan dong School of Electronic Science and Engineering University of Electronic Science and Technology of China

This paper proposes a wideband cavity-backed slotted patch antenna, loaded with a magneto-electric（ME）-dipole and fed by a microstrip line, for millimeter wave（mm-Wave） applications. The coupled-feed cavitybacked slotted patch antenna is loaded with the ME-dipole. The slotted patch antenna serves as both a radiator and a ground for the ME-dipole. The combination of the ME-dipole antenna and the slotted patch antenna realizes a –10 dB impedance bandwidth covering over 22.86–44.35 GHz（63.9%）. The pattern of the antenna element remains stable throughout this bandwidth. The proposed broadband antenna unit not only realizes single linearly polarized（LP）radiation but also can be designed for dual-LP radiation. The dual-polarized radiation can be achieved by changing the slot of the patch antenna to a crossed slot and altering the ME-dipole antenna to a dual-polarization form. A 2 × 2 dual-polarized array has been designed, fabricated, and tested. A novel dual-polarized feeding network is *** achieve higher isolation, broadband in-phase feed and differential feed are adopted, respectively. A low-loss single to the differential structure is proposed for differential feeding. The simulated isolation of the array is higher than 40 d *** results show that the dual-polarized 2 × 2 array has an overlapping bandwidth of 52.3%(|S11| < –10 dB and |S21| < –30 dB) with a peak gain of 14 dBi. The proposed antenna, featuring a wide overall bandwidth, low cost,and good radiation performance, is well suited for mm-Wave applications.

关键词： Slot antennas Costs Dipole antennas Patch antennas Magnetoelectric effects Broadband communication Broadband antennas Array antenna Dual-polarized antenna Feeding network Magneto-electric dipole Millimeter-wave (mm-Wave) Patch BROAD-BAND POLARIZED ANTENNA ARRAY PLANAR BALUN

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Integrated spatial-temporal random speckle spectrometer with high resolution in the C-band

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Photonics Research 2024年第7期12卷 1556-1563页

作者： SHIBO XU JIAHUI ZHANG JUNWEI cheng JIANJI dong Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Optics Valley Laboratory Wuhan 430074China

The increasing demand for diverse portable high-precision spectral analysis applications has driven the rapid development of spectrometer miniaturization. However, the resolutions of existing miniaturized spectrometers mostly remain at the nanometer level, posing a challenge for further enhancement towards achieving picometerlevel precision. Here, we propose an integrated reconstructive spectrometer that utilizes Mach–Zehnder interferometers and a tunable diffraction network. Through random tuning in the time domain and disordered diffraction in the space domain, the random speckle patterns closely related to wavelength information are obtained to construct the transmission matrix. Experimentally, we achieve a high resolution of 100 pm and precisely reconstruct multiple narrowband and broadband spectra. Moreover, the proposed spectrometer features a simple structure, strong portability, and fast sampling speed, which has great potential in the practical application of high-precision portable spectral analysis.

关键词： speckle random resolution

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Lightweight innovation ADIs help development of renewable energy and new technology industries in China

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China Foundry 2024年第5期21卷 507-515页

作者： Qi-dong Yan Xu-dong Gong Wen-bang Gong Jin-cheng Liu ADI Committee of China Foundry Association Beijing 100000China Yuzhou Henglilai New Materials Co. Ltd.Xuchang 452570HenanChina Kunshan Changjian Foundry Industry Co.Ltd. Kunshan 215311JiangsuChina School of Mechanical Engineering and Automation Wuhan Textile UniversityWuhan 430200China WFO Ferrous Metals Commission Shenyang 110022China

The world is undergoing profound changes in energy and *** are vigorously developing new sustainable energy sources and *** energy sources encompass various technologies such as wind turbines,solar energy,nuclear energy,and ***,emerging technology fields include new energy vehicles,robots,and artificial intelligence devices,among *** renewable energy industries and implementation of new technologies necessitate the development and adoption of new equipment and *** ductile iron(ADI)is renowned for its unique microstructure and superior *** utilizing ADI,lightweight and innovative castings can be designed to not only reduce weight but also save energy and decrease *** importantly,these castings enhance the efficiency and reliability of new energy equipment and emerging technology *** paper describes the development,applications,and future prospects of lightweight and innovative ADI castings within sectors such as solar photovoltaic(PV),wind power generation,industry robots,and trucks in China.

关键词： lightweight ADI renewable energy emission reduction

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Spacelike Framed Curves with Lightlike Components and Singularities of Their Evolutes and Focal Surfaces in Minkowski 3-space

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1521-1532页

作者： Peng cheng LI dong He PEI Xin ZHAO School of Mathematics and Statistics Northeast Normal UniversityChangchun 130024P.R.China Department of Mathematics Harbin Institute of TechnologyWeihai 264209P.R.China School of Mathematics and Statistics Qingdao UniversityQingdao 266071P.R.China

In this paper,we define the evolute and focal surface of a spacelike framed curve with lightlike components in Minkowski *** is a generalization of the previous results of regular spacelike curves,since singularities are allowed in the original spacelike curves studied by spacelike framed curves with lightlike ***,we show a new geometric invariant to characterise singularities of the focal ***,the classification theorem and recognition theorem for the singularities of the focal surface in generic are also given.

关键词： Evolutes focal surfaces spacelike framed curves singularities

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An unprecedented synthesis of axially chiral biaryls by rearrangement and aromatization of carbocations with central-to-axial conversion of chirality

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Science China Chemistry 2024年第9期67卷 2998-3003页

作者： Qi Liu Xue-dong Li Liang cheng Li Liu Beijing National Laboratory for Molecular Sciences(BNLMS) CAS Key Laboratory of Molecular Recognition and FunctionCAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

The central-to-axial chirality conversion represents a fascinating class of chemical processes consisting of the destruction of stereogenic centers and the simultaneous installation of axial chiral elements,which provides efficient methods for the preparation of axially chiral ***,developing catalytic asymmetric approaches for constructing these central chirality precursors and the efficient central-to-axial chirality conversion remains a challenge due to the requirement of aromatization or elimination *** this work,we have developed an unprecedented enantioselective intramolecular FriedelCrafts alkylation with unactivated-ketone carbonyls from which a chiral tertiary alcohol was generated with high efficiency and excellent *** addition,the central-to-axial chirality conversion strategy has been successfully applied to the synthesis of enantioenriched biaryls via a less-explored carbocation-initiated rearrangement and aromatization under the promotion of Lewis *** methodology provided a straightforward and sustainable access to a broad range of biaryl-2-carboxylic acid and in excellent yields(up to 92%)and excellent central-to-axial chirality conversion(up to 99%conversion percentage).This work could be a great model for developing new methods for synthesizing axially chiral biaryls and a general protocol for the rearrangement and aromatization of carbocations for further functionalization.

关键词： br?nsted acid catalysis desymmetrization phosphoric acid axially chiral biaryls central-to-axial conversion

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Nuclearity and Finite-Representability in the System of Completely Integral Mapping Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1197-1214页

作者： Zhe dong Ji cheng TAO Ya Fei ZHAO Department of Mathematics Zhejiang UniversityHangzhou 310027P.R.China Department of Mathematics China Jiliang UniversityHangzhou 310018P.R.China Department of Mathematics Zhejiang International Studies UniversityHangzhou 310023P.R.China

In this paper,we investigate local properties in the system of completely integral mapping *** introduce notions of injectivity,local reflexivity,exactness,nuclearity,finite-represent ability and WEP in the system of completely integral mapping *** we obtain that any finite-dimensional operator space is injective in the system of completely integral mapping *** we prove that C is the unique nuclear operator space and the unique exact operator space in this *** also show that C is the unique operator space which is finitely representable in{T_(n)}n∈Nin this *** corollaries,Kirchberg’s conjecture and QWEP conjecture in the system of completely integral mapping spaces are false.

关键词： Completely integral mapping space injectivity exactness nuclearity finite-representability WEP

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