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Advances in Climate Change Research 2024年第4期15卷 573-583页

作者： Jun LIU Xiao-Fan WANG dong-you wu Xin WANG Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmospheric SciencesLanzhou UniversityLanzhou 730000China

Arctic warming played a dominant role in recent occurrences of extreme events over the Northern Hemisphere,but climate models cannot accurately simulate the *** a significant positive correlation(0.33-0.95)between extreme precipitation and Arctic amplification(AA)is found using observations and CMIP5/6 multi-model ***,CMIP6 models are superior to CMIP5 models in simulating the temporal evolution of extreme precipitation and *** to 14 optimal CMIP6 models,the maximum latitude of planetary waves and the strength of Northern Hemisphere annular mode(NAM)will increase with increasing AA,contributing to increased extreme precipitation over the Northern *** the Shared Socioeconomic Pathway SSP5-8.5,AA is expected to increase by 0.85℃ per decade while the maximum latitude of planetary waves will increase by 2.82°per ***,the amplitude of the NAM will increase by 0.21 hPa per decade,contributing to a rise in extreme precipitation of 1.17% per decade for R95pTOT and 0.86% per decade for R99pTOT by 2100.

关键词： Arctic amplification Extreme precipitation CMIP5 CMIP6 Model evaluation Planetary waves Northern hemisphere annular mode

Study of Lyapunov exponent spectra for axial-flow compression system

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通讯和计算机（中英文版） 2008年第6期5卷 61-65页

作者： ZHANG Jian dong Fu-an wu you-li wu Xue-hui Engineering College Air Force Engineering University Xi＇an 710038 China

Length-Changeable Incremental Extreme Learning Machine

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Journal of Computer Science & Technology 2017年第3期32卷 630-643页

作者： you-Xi wu dong Liu He Jiang School of Computer Science and Software Hebei University of Technology Tianjin 300130 China School of Economics and Management Hebei University of Technology Tianjin 300130 China Hebei Province Key Laboratory of Big Data Calculation Tianjin 300401 China School of Software Dalian University of Technology Dalian 116621 China

Extreme learning machine （ELM） is a learning algorithm for generalized single-hidden-layer feed-forward networks （SLFNs）. In order to obtain a suitable network architecture, Incremental Extreme Learning Machine （I-ELM） is a sort of ELM constructing SLFNs by adding hidden nodes one by one. Although kinds of I-ELM-class algorithms were proposed to improve the convergence rate or to obtain minimal training error, they do not change the construction way of I-ELM or face the over-fitting risk. Making the testing error converge quickly and stably therefore becomes an important issue. In this paper, we proposed a new incremental ELM which is referred to as Length-Changeable Incremental Extreme Learning Machine （LCI-ELM）. It allows more than one hidden node to be added to the network and the existing network will be regarded as a whole in output weights tuning. The output weights of newly added hidden nodes are determined using a partial error-minimizing method. We prove that an SLFN constructed using LCI-ELM has approximation capability on a universal compact input set as well as on a finite training set. Experimental results demonstrate that LCI-ELM achieves higher convergence rate as well as lower over-fitting risk than some competitive I-ELM-class algorithms.

关键词： single-hidden-layer feed-forward network (SLFN) incremental extreme learning machine (I-ELM) random hidden node convergence rate universal approximation

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury

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Neural Regeneration Research 2025年第9期20卷 2611-2623页

作者： Mengshi Yang Miao Bai Yuan Zhuang Shenghua Lu Qianqian Ge Hao Li Yu Deng Hongbin wu Xiaojian Xu Fei Niu Xinlong dong Bin Zhang Baiyun Liu Beijing Tiantan Hospital Capital Medical UniversityBeijingChina Department of Neurology The First Hospital of Tsinghua UniversityBeijingChina Department of Neurotrauma and Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Critical Care Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersChina National Clinical Research Center for Neurological DiseasesBeijingChina

Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently *** potent anti-inflammato ry agents,the use of glucoco rticoids in traumatic brain injury is still controversial,and their regulatory effects on microglial polarization are not yet *** the present study,we sought to determine whether exacerbation of traumatic brain injury caused by high-dose dexamethasone is related to its regulatory effects on microglial polarization and its mechanisms of *** vitro cultured BV2 cells and primary microglia and a controlled cortical impact mouse model were used to investigate the effects of dexamethasone on microglial ***,dexamethasone,RU486(a glucocorticoid receptor antagonist),and ruxolitinib(a Janus kinase 1 antagonist)were ***-sequencing data obtained from a C57BL/6 mouse model of traumatic brain injury were used to identify potential targets of *** Morris water maze,quantitative reverse transcription-polymerase chain reaction,western blotting,immunofluorescence and confocal microscopy analysis,and TUNEL,Nissl,and Golgi staining were performed to investigate our ***-throughput sequencing results showed that arginase 1,a marker of M2 microglia,was significantly downregulated in the dexamethasone group compared with the traumatic brain injury group at3 days post-traumatic brain *** dexamethasone inhibited M1 and M2 microglia,with a more pronounced inhibitory effect on M2microglia in vitro and in *** receptor plays an indispensable role in microglial polarization after dexamethasone treatment following traumatic brain ***,glucocorticoid receptor activation increased the number of apoptotic cells and neuronal death,and also decreased the density of dendritic spines.A possible downstream receptor signaling mechanism is th

关键词： apoptosis BV2 microglia dexamethasone glucocorticoid receptor glucocorticoids innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury

Joint Task Scheduling, Resource Allocation, and UAV Trajectory under Clustering for FANETs

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China Communications 2022年第1期19卷 104-118页

作者： Wenjing you Chao dong Qihui wu Yuben Qu Yulei wu Rong He The Key Laboratory of Dynamic Cognitive System of Electromagnetic Spectrum Space Ministry of Industry and Information TechnologyNanjing University of Aeronautics and AstronauticsNanjing 211106China AVIC Chengdu Aircraft Design and Research Institute China

This paper establishes a new layered flying ad hoc networks(FANETs) system of mobile edge computing(MEC) supported by multiple UAVs,where the first layer of user UAVs can perform tasks such as area coverage, and the second layer of MEC UAVs are deployed as flying MEC sever for user UAVs with computing-intensive tasks. In this system, we first divide the user UAVs into multiple clusters, and transmit the tasks of the cluster members(CMs) within a cluster to its cluster head(CH). Then, we need to determine whether each CH’ tasks are executed locally or offloaded to one of the MEC UAVs for remote execution(i.e., task scheduling), and how much resources should be allocated to each CH(i.e., resource allocation), as well as the trajectories of all MEC *** formulate an optimization problem with the aim of minimizing the overall energy consumption of all user UAVs, under the constraints of task completion deadline and computing resource, which is a mixed integer non-convex problem and hard to solve. We propose an iterative algorithm by applying block coordinate descent methods. To be specific, the task scheduling between CH UAVs and MEC UAVs, computing resource allocation, and MEC UAV trajectory are alternately optimized in each iteration. For the joint task scheduling and computing resource allocation subproblem and MEC UAV trajectory subproblem, we employ branch and bound method and continuous convex approximation technique to solve them,respectively. Extensive simulation results validate the superiority of our proposed approach to several benchmarks.

关键词： flying ad hoc networks(FANETs) successive convex approximation clustering mobile edge computing(MEC)

Effect of Sintering Conditions on Structure of Manganese Zinc Ferrite Powders

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Chinese Journal of Aeronautics 2006年第B12期19卷 179-182页

作者： dong Li-min HAN Zhi-dong wu Ze ZHANG Xian-you College of Materials Science and Engineering Harbin University of Science and Technology Harbin 150040 China

The structures of the Mn-Zn ferrites synthesized under different sintering conditions by the sol-gel method were investigated by the X-ray diffraction （XRD） and the scanning electron microscopy （SEM） with focus on two factors： the pre-sintering treatment and the calcining time. The results show that the sintering conditions have significant effects on the structures and the particle size of the Mn-Zn ferrites. Compared with the products without pre-sintering, those pre-sintered at 500℃ have a single phase and no diffraction peaks of Fe2O3 that could be found. The effects of the pre-sintering temperature on the structures of the ferrites were also studied. As a result, 500℃ proves to be the favorite in the pre-sintering treatment. The XRD patterns of the ferrites calcined at 1 200℃ for 6 h will present diffraction peaks of pure crystallization of spinel phase while those for 2 h or 4 h will show peaks of Fe2O3. The SEM also bears witness to well-grown grains of pure Mn-Zn ferrites if calcined for 6 hours.

关键词： manganese zinc ferrite spinel sol-gel sintering time

Electric power generation technology of natural gas pressure reduction:Insights from black box-gray box hierarchical exergy analysis and evaluation method

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Petroleum Science 2022年第1期19卷 329-338页

作者： Zhi-dong Li Qing-Lin Cheng you-Wang Chen Jiang-dong Wei Li-Li Lv Hao wu Yang Liu Key Lab of Ministry of Education for Enhancing the Oil and Gas Recovery Ratio Northeast Petroleum UniversityDaqing 163318China PetroChina Planning&Engineering Institute(CPPEI) Beijing 100000China

Based on the“three box”exergy analysis model,a black box-gray box hierarchical exergy analysis and evaluation method is put forward in this paper,which is applied to evaluate the power generation technology of differential pressure produced by natural gas *** using the exergy analysis theory,the black box-gray box hierarchical exergy analysis models of three differential pressure power generation technologies are established ***,the“black box”analysis models of main energy consuming equipment are established,and then the“gray box”analysis model of the total system is *** on the calculation results of exergy analysis indexes,the weak energy consumption equipment in the whole power generation process is accurately *** a gas field in southwest China as an example,the comprehensive energy consumption evaluation of the three power generation technologies is carried out,and the technology with the best energy consumption condition among the three technologies is ***,the rationalization improvement measures are put forward from improving the air tightness,replacing the deflector and reducing the flow loss.

关键词： Expansion differential pressure power generation Black box-gray box hierarchy Exergy analysis method Weak link of energy consumption

Preoperative lymphocyte to C-reactive protein ratio as a new prognostic indicator in patients with resectable gallbladder cancer

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Hepatobiliary & Pancreatic Diseases International 2022年第3期21卷 267-272页

作者： Wen-Yan Yao Xiang-Song wu Shi-Lei Liu Zi-you wu Ping dong Wei Gong Department of General Surgery Xinhua HospitalAffiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Shanghai Key Laboratory of Biliary Tract Disease Research Shanghai 200092China

Background:Inflammation is often related to cancer,and several inflammatory scores have been established to predict the prognosis of various types of *** study aimed to determine the prognostic value of the preoperative lymphocyte to C-reactive protein ratio(LCR)for predicting postoperative outcomes in patients with resectable gallbladder cancer(GBC).Methods:A retrospective analysis of 104 GBC patients who received curative surgery at Xinhua Hospital,Affiliated to Shanghai Jiao Tong University School of Medicine from January 2000 to December 2016 was performed.A time-dependent receiver operating characteristic curve was constructed to evaluate the accuracy of different *** and multivariate Cox proportional hazard models were used to define factors associated with overall ***:Among the assessed variables,the preoperative LCR showed the highest accuracy in predicting the overall survival of GBC patients(AUC:0.736).Decreased preoperative LCR was significantly associated with advanced tumor stage,including tumor invasion(P=0.018),lymph node metastasis(P=0.011)and TNM stage(P=0.022).A low preoperative LCR(cutoff threshold=145.5)was an independent risk factor for overall survival in patients with resectable GBC(P<0.001).Conclusions:The preoperative LCR is a novel and valuable prognostic indicator of postoperative survival in patients with resectable GBC.

关键词： Gallbladder neoplasms Inflammation Lymphocyte to C-reactive protein ratio Overall survival

减氮及有机肥替代对旱地冬小麦干物质积累、转运、分配和产量的影响

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作物学报 2025年第1期51卷 207-220页

作者：张军胡川周起晖任开明董誓言刘傲寒吴金芝黄明李友军河南科技大学农学院河南洛阳471023 商洛学院生物医药与食品工程学院陕西商洛726000

探究减氮及有机肥替代对旱地冬小麦产量形成和经济效益的影响,为实施化肥减量和有机肥替代提供理论和技术依据。2021-2023年度,基于2019年开始设置在黄土高原和黄淮海平原交汇处典型旱地冬小麦产区(河南洛宁和河南孟津)的定位试验,研究... 详细信息

探究减氮及有机肥替代对旱地冬小麦产量形成和经济效益的影响,为实施化肥减量和有机肥替代提供理论和技术依据。2021-2023年度,基于2019年开始设置在黄土高原和黄淮海平原交汇处典型旱地冬小麦产区(河南洛宁和河南孟津)的定位试验,研究了冬小麦干物质积累转运分配特性、氮肥干物质生产效率、产量及其构成要素和经济效益。试验设置不施氮肥(NN)、农户施氮(FN)、基于FN减氮20%(RN)和RN基础上20%氮肥用有机肥替代(OSN)4个处理。结果表明:(1)与FN相比,RN处理降低了小麦拔节期、开花期和成熟期的干物质积累量、花前干物质转运量以及成熟期茎鞘、穂轴+颖壳和籽粒的干物质分配量,但对籽粒产量无显著影响。(2)与FN和RN相比, OSN处理提高了各生育阶段的氮肥干物质生产效率,从而增加了拔节期、开花期、成熟期的干物质积累量,而且提高了花前干物质转运量、花后干物质积累量、花后干物质积累量对籽粒的贡献率,进而使成熟期地上部各器官的干物质分配量均得到显著提高,最终使籽粒产量分别显著增加15.03%和17.12%,经济效益增加3.84%和4.23%。(3)小麦产量与花前干物质转运量、花后干物质积累量和花后干物质积累量对籽粒的贡献率呈极显著正相关,与花前干物质转运量对籽粒的贡献率呈极显著负相关。综上,在雨养条件下,小麦季施氮量为172kghm^(–2) (夏休闲-冬小麦)和192kg hm^(–2) (夏玉米-冬小麦)的基础上,OSN处理提高了氮肥干物质生产效率,增加各生育时期的干物质积累量,其花前干物质转运量和花后干物质积累量的协同增加使其获得了最高产量,实现增产增收,适宜在产量水平为5000kghm^(–2)的雨养旱地冬小麦高产栽培中应用。

关键词：旱地冬小麦减氮有机肥替代干物质积累转运产量经济效益

Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex promotes intestinal development as a new iron supplement

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Science China Life Sciences 2025年第01期 219-231页

作者： Yingying Feng Yuying wu Jialu Wang Zhenglin dong Qian Yu Shuangshuang Xia Chunxue Liu Haihua Wang Xin wu Tianjin Institute of Industrial Biotechnology Chinese Academy of Sciences CAS Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of Sciences ANyou Biotechnology Group Co.Ltd Qingdao Seawin Biotech Group Co. LTD

Iron is a crucial micronutrient, and its deficiency can have detrimental effects on the health of infants. Dietary polysaccharide-iron(Ⅲ) complexes(PICs) are promising for addressing iron deficiency due to their minimal adverse reactions and high iron absorption rate. This study aimed to investigate the effects of dietary Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex(EP-Fe) on newborns, using 3-day weaned piglets as the iron-deficiency model. Results showed that EP-Fe improved iron levels and promoted intestinal development in piglets. Transcriptome sequencing revealed that EP-Fe increased the survival of intestinal epithelial cells under hypoxia by upregulating the expression of genes that promote the development of the vascular system. Additionally, EP-Fe enhanced the mucosal barrier functions by inhibiting myosin light chain kinase(MLCK)/phosphorylated myosin light chain(p-MLC) signaling pathway to increase the expression of intestinal tight junction proteins. Furthermore, the 16S r RNA gene sequencing of gut microbiota showed that EP-Fe promoted the enrichment of Bacteroides＿fragilis and other gut microbes that can metabolize carbohydrates. In conclusion, EP-Fe is an effective iron supplement for newborns, and it can be developed as a comprehensive nutritional supplement.

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