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Knowledge-oriented modeling for influencing factors of battle damage in military industrial logistics:An integrated method

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Defence Technology（防务技术） 2020年第3期16卷 571-587页

作者： Xiong Li xiao-dong zhao Wei Pu Military Exercise and Training Center Army Academy of Armored ForcesBeijing 100072China

Modeling influencing factors of battle damage is one of essential works in implementing military industrial logistics simulation to explore battle damage laws ***,one of key challenges in designing the simulation system could be how to reasonably determine simulation model input and build a bridge to link battle damage model and battle damage laws *** this paper,we propose a novel knowledge-oriented modeling method for influencing factors of battle damage in military industrial logistics,integrating conceptual analysis,conceptual modeling,quantitative modeling and simulation *** conceptualize influencing factors of battle damage by using the principle of hierarchical decomposition,thus classifying the related battle damage knowledge ***,we construct the conceptual model of influencing factors of battle damage by using Entity-Relations hip approach,thus describing their interactions ***,we extract the important influencing factors by using social network analysis,thus evaluating their importance quantitatively and further clarifying the elements of ***,we develop an agent-based military industry logistics simulation system by taking the modeling results on influencing factors of battle damage as simulation model input,and obtain simulation model output,i.e.,new battle damage laws knowledge,thus verifying feasibility and effectiveness of the proposed *** results show that this method can be used to support human decision-making and action.

关键词： Battle damage Industrial logistics Entity-relationship approach Social network analysis Agent-based simulation

Current understanding of ELF4 deficiency:a novel inborn error of immunity

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World Journal of Pediatrics 2024年第5期20卷 444-450页

作者： Hong-Qiang Du xiao-dong zhao Department of Rheumatology&Immunology National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChongqing Key Laboratory of Child Rare Diseases in Infection and ImmunityChildren’s Hospital of Chongqing Medical UniversityZhongshan Er Road 136Yuzhong DistrictChongqingChina

Background ELF4 deficiency has been recently recognized as a novel disorder within the spectrum of inborn errors of immunity(IEIs),specifically categorized as a“disease of immune dysregulation.”Cases of this condition,reported by our team and others,are very limited *** such,our current knowledge of this new disease remains *** review aims to provide a brief overview of the clinical manifestations,pathogenesis,and treatment strategies for this novel *** sources A comprehensive review was conducted after an extensive literature search in the PubMed/Medline database and websites concerning transcriptional factor ELF4 and reports concerning patients with ELF4 *** search strategy was“ELF4 OR ETS-related transcription factor Elf-4 OR EL4-like factor 4 OR myeloid Elf-1-like factor”as of the time of manuscript *** The current signature manifestations of ELF4 deficiency disorder are recurrent and prolonged oral ulcer,abdominal pain,and diarrhea in pediatric *** some cases,immunodeficiency and autoimmunity can also be *** Sanger sequencing or whole exome sequencing can be used to detect variation in ELF4 *** blotting for ELF4 expression of the patient’s cells can confirm the pathogenic effect of the *** fully confirm the pathogenicity of the variant,further functional test is strongly *** and biologics are the mainstream management of ELF4 deficiency *** Pediatric males presenting with recurring ulcerations in digestive tract epithelium with or without recurrent fever should be suspected of *** atypical presentations are prominent,variations in ELF4 gene should be carefully evaluated functionally due to the complex nature of ELF4 *** of treating DEX includes use of glucocorticoid and biologics and more precise treatment needs more patients to identify and further mechanistic study.

关键词： ELF4 transcription factor Immune dysregulation Inborn errors of immunity Mechanism Recurrent infections

Delay-dependent robust control for uncertain discrete singular systems with time-varying delay

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第8期9卷 1034-1042页

作者： Hui-jiao WANG xiao-dong zhao An-ke XUE Ren-quan LU Institute of Automation Zhejiang Sci- Tech University Hangzhou 310018 China Institute of Information and Control Hangzhou Dianzi University Hangzhou 310018 China

The design problem of delay-dependent robust control for uncertain discrete singular systems with time-varying delay is addressed in this paper. The uncertainty is assumed to be norm-bounded. By establishing a finite sum inequality based on quadratic terms, a new delay-dependent robust stability condition is derived and expressed in terms of linear matrix inequalities (LMIs). A suitable robust state feedback control law is presented, which guarantees that the resultant closed-loop system is regular, causal and stable for all admissible uncertainties. Numerical examples are given to demonstrate the applicability of the proposed method.

关键词： Uncertain discrete singular system Time-varying delay Robust control Linear matrix inequality (LMI)

Selective and stable elimination of endosymbionts from multiple-infected whitefly Bemisia tabaci by feeding on a cotton plant cultured in antibiotic solutions

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Insect Science 2020年第5期27卷 964-974页

作者： dong-xiao zhao Zhi-Chun Zhang Hong-Tao Niu Hui-Fang Guo Institute of Plant Protection Jiangsu Academy of Agricultural SciencesNanjingChina

The maternally heritable endosymbiont provides many ecosystem *** elimination of a specific symbiont and establishment of experimental host lines lacking certain symbionts enable the roles of a given symbiont to be *** whitefly Bemisia tabaci(Gennadius)in China harbors obligate symbiont Portiera infecting each in-dividual,as well as facultative symbionts,such as Hamiltonella,Rickettsia and Cardinium,with co-infections occurring relatively *** far no studies have evaluated the selectivity and efficacy of a specific symbiont elimination using antibiotics in whiteflies co-infected with different ***,no success has been achieved in estab-lishing certain symbiont-free *** *** this study,we treated Hamiltonella infected *** line,Hamiltonella-Rickettsia-co infected line and Hamiltonella-Cardinium co-infected line by feeding *** adults with cotton plants cultured in water containing ri-fampicin,ampicillin or a mixture of them,aiming to selectively curing symbiont infections and establishing stable symbiont-free *** found ampicillin selectively eliminated Cardinium without afecting Portiera,Hamiltonella and Rickettsia,although they coex-isted in the same host ***,all of the symbionts considered in our study can be removed by *** reduction of facultative symbionts occurred at a much quicker pace than obligate symbiont Portiera during rifampicin ***,we measured the stability of symbiont elimination in whitefly successive generations and established Rickettsia-infected and Cardinium-infected lines which are absent in natural *** results provide new protocols for selective elimination of symbionts co-existing in a host and establishment of different symbiont-infected host lines.

关键词： antibiotic treatment Bemisia tabaci co-infections endosymbionts infection frequency

A novel homozygous RAG1 mutation in a girl presenting with granulomas and alopecia capitis totalis

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World Journal of Pediatrics 2022年第4期18卷 294-299页

作者： Yu Ruan Qin zhao Qing Liu Hong-Yi zhao Zhi-Yong Zhang Yuan Ding xiao-dong zhao Growth Developmentand Mental Health Center of Children and AdolescentsChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Chongqing Key Laboratory of Child Infection and Immunity Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChildren’s Hospital of Chongqing Medical University136 Zhongshan 2nd RoadYu Zhong DistrictChongqing 400014China Department of Rheumatology and Immunology Children’s Hospital of Chongqing Medical UniversityChongqing 400014China

Recombination-activating gene 1(RAG1)mutations in humans vary in residual recombination activity and result in heterogeneous clinical phenotypes[1,2].In recent years,RAG deficiency with a milder clinical course and delayed presentation has been *** patients present with generalized granulomas,severe complications after viral infections,hypogammaglobulinemia,and various autoimmune manifestations(such as cytopenias,vitiligo,psoriasis,myasthenia gravis,and Guillain-Barre syndrome)[3-17].

关键词： granuloma clinical gravis

Synthesis of 3-hydroxyflavone fluorescent probes and study of their fluorescence properties

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Chinese Chemical Letters 2010年第5期21卷 529-532页

作者： xiao dong zhao Chang Jun Sun Qing Qiang Yao Wen Bao Li Institute of Materia Medica Shandong Academy of Medical SciencesJinan 250062China Sanlugen Pharma Tech 18877 Jingshi RoadJinan 250062China

Direct measurement of dipole potential in biological membranes has been impossible and 3-hydroxyflavones(3HFs) have allowed detection of changes in dipole potential in biological *** the present study,sixteen derivatives of 3HF with aliphatic hydrocarbon chains of different lengths at 4′-position and 6-position were *** basic fluorescence properties of 3HFs are maintained in all the probes in terms of strong blue shift in maximum fluorescence emission wavelength and>100 fold increase in quantum yield in organic solvents and in dioleoylphosphatidylcholine(DOPC) small unilamellar vesicles(SUV) in comparison to in aqueous Hepes buffer(15 mmol/L,pH 7.4).More importantly,the ability of the new compounds to report dipole potential changes in biological systems are also maintained,since all the new probes showed spectrum properties that are similar to yet different from that of F4N1,which potentially may allow more sensitive measurement of the dipole potential change in membranes.

关键词： 3-Hydroflavones(3HFs) Fluorescent probes ESIPT Dipole potential

Multi-wavelength continuous-wave Nd:YVO4 self-Raman laser under in-band pumping

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Chinese Physics B 2019年第8期28卷 184-189页

作者： Li Fan xiao-dong zhao Yun-Chuan Zhang xiao-dong Gu Hao-Peng Wan Hui-Bo Fan Jun Zhu College of Physics Science and Technology Institute of Applied Photonic Technology Yangzhou University

Multi-wavelength continuous-wave self-Raman laser with an a-cut composite YVO4/Nd:YVO4/YVO4 crystal pumped by an 879-nm wavelength-locked laser diode is demonstrated for the first ***-wavelength Raman lasers at 1168.4,1176,1178.7,and 1201.6 nm are achieved by the first Stokes shift of the multi-wavelength fundamental lasers at 1064,1066.7,1073.6,1084,and 1085.6 nm with two Raman shifts of 890 and 816 cm^-1.A maximum Raman output power of 2.56 W is achieved through the use of a 20-mm-long composite crystal,with a corresponding optical conversion efficiency of 9.8%.The polarization directions of different fundamental and Raman lasers are investigated and found to be orthogonalπandσ*** orthogonally polarized multi-wavelength lasers with small wavelength separation pave the way to the development of a potential laser source for application in spectral analysis,laser radar and THz generation.

关键词： multi-wavelength continuous-wave self-Raman laser in-band pumping

System utility based resource allocation for multi-cell OFDM system

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The Journal of China Universities of Posts and Telecommunications 2010年第2期17卷 14-18,45页

作者： HAO Zhi-jie XU xiao-dong zhao Ying-hong TAO xiao-feng LI Lin-jun ZHANG Zhong-qi Wireless Technology Innovation Institute Key Laboratory of Universal Wireless Communication Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

Utility based resource allocation strategy in multi-cell orthogonal frequency-division multiplexing （OFDM） system plays a critical role in next generation mobile communication systems. Based on the analysis of risk aversion utility functions, this article proposed the system utility based utility, which is named the customer satisfaction （CS） utility. Compared with the proportional fairness （PF） utility, the CS utility reflects the user demands better, and enables the system to adjust its resource allocation according to both the traffic requirements and the resource situation.

关键词： OFDM resource allocation utility multi-cell

All-solid-state microscopic interferometer with frequency-variation and phase-shifting capability

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Optoelectronics Letters 2007年第2期3卷 123-125页

作者： TIAN Jin-dong zhao xiao-bo PENG Xiang Institute of Optoelectronics and Key laboratory of Optoelectronic Devices and Systems of Education Ministry Shenzhen Uuiversity Shenzhen 518060 China

A novel microscopic interferometry with ability of frequency-variation and phase-shifting is proposed for microstructures testing. By using acousto-optic technique, sequential carriers can be generated with different spatial frequencies so that the temporal phase unwrapping method can be applied for decoding the height information. Combined with phase-shifting technique realized by spatial light modulator, this method is especially suitable for interferometric measurement with high precision and large dynamic range.

关键词：全固态显微干涉仪频率变异相移能力显微结构测试