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Differences in Pandemic-Related Factors Associated with Alcohol and Substance Use among Korean Adolescents:Nationwide Representative Study

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Biomedical and Environmental Sciences 2023年第6期36卷 542-548页

作者： Hyunju Yon Sangil Park Jung U Shin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min Jinseok Lee Rosie Kwon Guillaume Fond Laurent Boyer Sunyoung Kim Namwoo Kim Sang Youl Rhee Jae Il Shin dong Keon Yon Ho Geol woo Department of Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Neurology Kyung Hee University Medical CenterSeoulRepublic of Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamRepublic of Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Department of Physical Medicine and Rehabilitation Lariboisière-Fernand Widal HospitalAP-HPUniversity Paris CitéParisFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulRepublic of Korea Department of Biomedical Engineering Kyung Hee UniversityYonginRepublic of Korea Assistance Publique-Hôpitaux de Marseille(AP-HM) Aix-Marseille UniversityCEReSSHealth Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Family Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Psychiatry Seoul St.Mary's HospitalThe Catholic University of KoreaCollege of MedicineSeoulRepublic of Korea Department of Endocrinology and Metabolism Kyung Hee University School of MedicineSeoulRepublic of Korea Department of Pediatrics Yonsei University College of MedicineSeoulRepublic of Korea Department of Pediatrics Kyung Hee University College of MedicineSeoulRepublic of Korea

The coronavirus disease 2019(COVID-19)pandemic has raised concerns about the mental health and social well-being of youth,including its potential to increase or exacerbate substance use behaviors[1].Among adolescents,the COVID-19pandemic has resulted in limited face-to-face school contact and thus missed milestones in preventing alcohol and substance use.

关键词： Alcohol raised alcohol

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Enhancement of ballistic performance enabled by transformation-induced plasticity in high-strength bainitic steel

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Journal of Materials Science & Technology 2021年第25期84卷 219-229页

作者： Min Cheoljo Selim Kim dong woo Suh Hong Kyu Kim Yongjin Kim Seok Su Sohn Sunghak Lee Center for Advanced Aerospace Materials Pohang University of Science and TechnologyPohang37673South Korea Graduate Institute of Ferrous Technology Pohang University of Science and TechnologyPohang37673South Korea Materials Directorate Agency for Defense DevelopmentDaejeon305-600South Korea Department of Materials Science and Engineering Korea UniversitySeoul02841South Korea

High-strength bainitic steels have created a lot of interest in recent times because of their excellent combination of strength,ductility,toughness,and high ballistic mass *** steels have great potential in the fabrication of steel armor *** various approaches and methods have been conducted to utilize the retained austenite(RA)in the bainitic matrix to control mechanical properties,very few attempts have been conducted to improve ballistic performance utilizing transformationinduced plasticity(TRIP)*** this study,high-strength bainitic steels were designed by controlling the time of austempering process to have various volume fractions and stability of RA while maintaining high *** dynamic compressive and ballistic impact tests were conducted,and the relation between the effects of TRIP on ballistic performance and the adiabatic shear band(ASB)formation was *** results show for the first time that an active TRIP mechanism achieved from a large quantity of metastable RA can significantly enhance the ballistic performance of high-strength bainitic steels because of the improved resistance to ASB ***,the ballistic performance can be effectively improved by a very short austempering time,which suggests that the utilization of active TRIP behavior via tuning RA acts as a primary mechanism for significantly enhancing the ballistic performance of high-strength bainitic steels.

关键词： High-strength bainitic steel Ballistic performance Split Hopkinson pressure bar(SHPB) Adiabatic shear band(ASB) Retained austenite(RA) Transformation-induced plasticity(TRIP)

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Characteristics and biological control functions of Bacillus ***8313 as a host-associated probiotic in red sea bream(Pagrus major)aquaculture

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Animal Nutrition 2023年第1期12卷 20-31页

作者： Won Je Jang Kyung-Bon Lee Mi-Hyeon Jeon Su-Jeong Lee Sang woo Hur Seunghan Lee Bong-Joo Lee Jong Min Lee Kang-woong Kim Eun-woo Lee Department of Biotechnology Pukyong National UniversityBusan48513South Korea Department of Biology Education College of Education Chonnam National UniversityGwangju61186South Korea Biopharmaceutical Engineering Major Division of Applied BioengineeringDong-Eui UniversityBusan47340South Korea Aquafeed Research Center National Institute of Fisheries SciencePohang37517South Korea Department of Smart Fisheries Resources College of Industrial SciencesKongju National UniversityYesan32439South Korea

Host-associated probiotics(HAPs)are bacteria originally isolated from rearing water or the host's gastrointestinal tract in order to enhance the host's growth and *** study investigated the HAP potential of Bacillus ***8313,isolated from wild red sea bream(Pagrus major),through characterization and feeding *** based on in vitro tests showed that PM8313 is safe,confirming its hemolytic,cytotoxic,and antibiotic *** addition,PM8313 showed advantages as a probiotic with high viability in the gastrointestinal model and a high cell adhesion ***-genome sequencing demonstrated that PM8313 has a 4,615,871 bp single circular chromosome and a guaninecytosine content of 45.25%.It also showed the absence of genes encoding virulence factors,such as cytotoxin,enterotoxin,hemolysin,sphingomyelinase,and *** the feeding trial,a supplemental diet of 1×10^(8)CFU/g PM8313 positively altered the weight gain,digestive enzyme activity,and intestinal microbiota composition of red sea *** of nonspecific immune parameters and immune-related gene expression,and a challenge test showed that PM8313 supplementation increases immunity and pathogenic bacteria *** findings suggest that PM8313 should be considered for application as a novel HAP to red sea bream aquaculture.

关键词： Host-associated probiotics Immunity Microbiota Probiotics Red sea bream

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Tailoring uniform γ-MnO2 nanosheets on highly conductive three-dimensional current collectors for high-performance supercapacitor electrodes

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Nano Research 2015年第3期8卷 990-1004页

作者： Sangbaek Park Hyun-woo Shim Chan woo Lee Hee Jo Song Ik Jae Park Jae-Chan Kim Kug Sun Hong dong-Wan Kim Department of Materials Science and Engineering Seoul National University Seou1151-744 R. O. Korea School of Civil Environmental and Architectural Engineering Korea University Seou1136-713 R. O. Korea

最近的努力集中了于制造和应用程序三维(3-D ) nanoarchitecture 电极，它能展出优秀电气化学的性能。此处，向设计和合成的新奇策略尺寸悦耳、厚度悦耳二维( 2-D ) MnO 2 nanosheets 在上高度传导性一个维( 1-D )脊梁数组被开发了经... 详细信息

最近的努力集中了于制造和应用程序三维(3-D ) nanoarchitecture 电极，它能展出优秀电气化学的性能。此处，向设计和合成的新奇策略尺寸悦耳、厚度悦耳二维( 2-D ) MnO 2 nanosheets 在上高度传导性一个维( 1-D )脊梁数组被开发了经由一灵巧，一步舞提高了化学洗澡免职( ECBD )在低温度的方法( 50 湡睯物吗？？

关键词：纳米结构电极超级电容器电化学性能非均匀成核 MnO 高导电三维集流器

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Effects of Flexible Conjugation-Break Spacers of Non-Conjugated Polymer Acceptors on Photovoltaic and Mechanical Properties of All-Polymer Solar Cells

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Nano-Micro Letters 2022年第10期14卷 164-177页

作者： Qiaonan Chen Yung Hee Han Leandro R.Franco Cleber F.N.Marchiori Zewdneh Genene CMoyses Araujo Jin-woo Lee Tan Ngoc-Lan Phan Jingnan Wu donghong Yu dong Jun Kim Taek-Soo Kim Lintao Hou Bumjoon J.Kim Ergang Wang Siyuan Laboratory Guangzhou Key Laboratory of Vacuum Coating Technologies and New Energy MaterialsDepartment of PhysicsJinan UniversityGuangzhou 510632People’s Republic of China Department of Chemistry and Chemical Engineering Chalmers University of TechnologySE-41296GöteborgSweden Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Engineering and Physics Karlstad University65188 KarlstadSweden Department of Chemistry and Bioscience Aalborg University9220 AalborgDenmark Department of Mechanical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Materials Theory Division Department of Physics and AstronomyUppsala University75120 UppsalaSweden Sino-Danish Center for Education and Research 8000 AarhusDenmark School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001People’s Republic of China

All-polymer solar cells(all-PSCs)possess attractive merits including superior thermal stability and mechanical flexibility for large-area roll-to-roll *** flexible conjugation-break spacers(FCBSs)into backbones of polymer donor(P_(D))or polymer acceptor(P_(A))has been demonstrated as an efficient approach to enhance both the photovoltaic(PV)and mechanical properties of the ***,length dependency of FCBS on certain all-PSC related properties has not been systematically *** this regard,we report a series of new non-conjugated P_(A)s by incorporating FCBS with various lengths(2,4,and 8 carbon atoms in thioalkyl segments).Unlike com-mon studies on so-called side-chain engineering,where longer side chains would lead to better solubility of those resulting polymers,in this work,we observe that the solubilities and the resulting photovoltaic/mechanical properties are optimized by a proper FCBS length(i.e.,C2)in P_(A) named *** all-PSC achieves a high efficiency of 11.37%,and excellent mechanical robustness with a crack onset strain of 12.39%,significantly superior to those of the other P_(A)*** results firstly demonstrate the effects of FCBS lengths on the PV performance and mechanical properties of the all-PSCs,providing an effective strategy to fine-tune the structures of P_(A)s for highly efficient and mechanically robust PSCs.

关键词： All-polymer solar cells Flexible conjugation-break spacers Mechanical robustness Polymer acceptors Stretchability

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Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells

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World Journal of Gastroenterology 2009年第3期15卷 310-320页

作者： Chan woo Cheon Dae Hwan Kim dong Heon Kim Yong Hoon Cho Jae Hun Kim Department of Surgery School of MedicineMedical Research InstitutePusan National UniversityBusan 602-739South Korea

AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor(PPAR)-γ and PPAR-γ agonists on stomach cancer ***:To determine the proliferation-suppressive effects of troglitazone and ciglitazone,SNU-216 and SNU-668 stomach cancer cells were plated in media containing 40 μmol/L troglitazone and ciglitazone at a density of 1 × 104 cells/*** 3,5 and 7 d,the cells were counted with a *** assess the appearance of PPAR-γ,a reverse-transcription polymerase chain reaction analysis was *** day 7,Western blotting was used to determine the effects of troglitazone and ciglitazone on the expression of p21 and phosphorylated-ERK(pERK) *** cytometry analysis was used to determine which portion of the cell cycle was delayed when troglitazone was used to suppress cell *** order to clarify the mechanism underlying the activity of troglitazone,microarray analysis was ***:PPAR-γ was manifested in both SNU-216 and SNU-668 *** and troglitazone suppressed cell growth,and troglitazone was a stronger suppressor of stomach cancer cells than ciglitazone,an inducer of cell cycle arrest in the G1 ***-668 cells were also determined to be more sensitive to ciglitazone and troglitazone than SNU-216 *** troglitazone and ciglitazone were administered to stomach cancer cells,levels of p21 expression were increased,but ERK phosphorylation levels were *** GW9662,an antagonist of PPAR-γ,was applied in conjunction with ciglitazone and troglitazone,the cell growth suppression effect was *** gene transcription program revealed a variety of alterations as the consequence of troglitazone treatment,and multiple troglitazone-associated pathways were *** genes whose expression was increased by troglitazone treatment were associated with cell development,differentiation,signal transmission between cells,and cell adhesion,and were also associated

关键词：胃癌细胞增生活性分子效应

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Molecular Mechanism of the Specificity of Protein Import into Chloroplasts and Mitochondria in Plant Cells

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Molecular Plant 2019年第7期12卷 951-966页

作者： dong wook Lee Sumin Lee Junho Lee Seungjin woo Md.Abdur Razzak Alessandro Vitale Inhwan Hwang Division of Integrative Biosciences and Biotechnology Pohang University of Science and Technology Pohang 37673 Korea Department of Life Sciences Pohang University of Science and Technology Pohang 37673 Korea Istituto di Biologia e Biotecnologia Agraria Consiglio Nazionale Delle Ricerche Milano Italy

Plants possess both types of endosymbiotic organelles, chloroplasts and mitochondria. Transit peptides and presequences function as signal sequences for specific import into chloroplasts and mitochondria, respectively. However, how these highly similar signal sequences confer the protein import specificity remains elusive. Here, we show that mitochondrial- or chloroplast-specific import involves two distinct steps, specificity determination and translocation across envelopes, which are mediated by the N-terminal regions and functionally interchangeable C-terminal regions, respectively, of transit peptides and presequences. A domain harboring multiple-arginine and hydrophobic sequence motifs in the N-terminal regions of presequences was identified as the mitochondrial specificity factor. The presence of this domain and the absence of arginine residues in the N-terminal regions of otherwise common targeting signals confers specificity of protein import into mitochondria and chloroplasts, respectively. AtToc159, a chloroplast import receptor, also contributes to determining chloroplast import specificity. We propose that common ancestral sequences were functionalized into mitochondrial- and chloroplast-specific signal sequences by the presence and absence, respectively, of multiple-arginine and hydrophobic sequence motifs in the N-terminal region.

关键词： transit peptide presequence protein import into chloroplasts and mitochondria N-terminal specificity domain C-terminal common translocation domain import specificity determination

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低温CO氧化中担载Co_3O_4催化剂失活的影响因素(英文)

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催化学报 2011年第5期32卷 762-770页

作者： Moon Hyeon KIM dong woo KIM Department of Environmental Engineering Daegu University

This study focused on the influences of a variety of reaction parameters and guest molecules such as H2O and C3H8 on the deactivation of supported Co3O4 catalysts for CO ***,the physical features of and carbon deposition on some samples after the reaction under the chosen conditions were determined by BET and X-ray diffraction as well as by carbon analyses to deduce the precursors associated with catalyst *** maintenance profiles of the catalysts for CO oxidation at 100°C significantly depended on the support for Co3O4 nanoparticle dispersion,the loading,the preparation technique and the calcination *** best on-stream performance was achieved using a 5%Co3O4/TiO2 catalyst prepared by the incipient wetness method followed by calcination at 350°*** the reaction parameters chosen here such as the reaction temperature,the feed gas composition of CO,O2,H2O,and C3H8,and the gas space velocity strongly influenced the extent of catalyst deactivation during CO oxidation and also the rate of catalyst ***,the deactivation behavior is very *** appreciable changes in the surface area,the porosity,and the phase of the Co3O4 nanoparticles and their size occurred even for the samples that were severely *** deposition of carbon on the catalysts after the reaction was visible and it depended on the reaction parameters chosen ***,this extensive parametric study on the deactivation of catalysts during oxidation and with the chosen reaction parameters and guest gases can lead to an understanding of the deactivation precursors that are associated with carbonaceous species including carbonates and surface free carbon.

关键词： carbon monoxide oxidation supported cobalt oxides deactivation reaction parameters feed compositions

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Endoscopic management of occluded metal biliary stents:Metal versus 10F plastic stents

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World Journal of Gastroenterology 2010年第42期16卷 5347-5352页

作者： Won Jae Yoon Ji Kon Ryu Jung Won Lee dong-Won Ahn Yong-Tae Kim Yong Bum Yoon Sang Myung woo woo Jin Lee Division of Gastroenterology Department of Internal MedicineSeoul National University College of Medicine101 Daehang-roJongno-guSeoul110-744South Korea Center for Liver Cancer National Cancer Center323 Ilsan-roIlsandong-guGoyang-siGyeonggi-do410-769South Korea

AIM:To compare the efficacy of self-expandable metal stents(SEMSs) with 10F plastic stents(PSs) in the endoscopic management of occluded ***:We retrospectively reviewed the medical records of 56 patients who underwent SEMS insertion for palliation of unresectable malignant biliary obstruction between 2000 and 2007 and subsequent endoscopic retrograde biliary drainage(ERBD) with SEMS or PS for initial SEMS occlusion between 2000 and ***:Subsequent ERBD with SEMS was performed in 29 patients and with PS in *** median time to stent occlusion after subsequent ERBD was 186 d in the SEMS group and 101 d in the PS group(P= 0.118).Overall median stent patency was 79 d for the SEMS group and 66 d for the PS group(P = 0.379).The mean number of additional biliary drainage procedures after subsequent ERBD in patients that died(n = 50) during the study period was 2.54 ± 4.12 for the SEMS group and 1.85 ± 1.95 for the PS group(P = 0.457).The mean total cost of additional biliary drainage procedures after the occlusion of subsequent SEMS or PS was $410.04 ± 692.60 for the SEMS group and $630.16 ± 671.63 for the PS group(P = 0.260).Tumor ingrowth as the cause of initial SEMS occlusion was the only factor associated with a shorter time to subsequent stent occlusion(101 d for patients with tumor ingrowth vs 268 d for patients without tumor ingrowth,P = 0.008).CONCLUSION:Subsequent ERBD with PSs offered similar patency and number of additional biliary drainage procedures compared to SEMSs in the management of occluded SEMS.

关键词： Stents Biliary tract neoplasms Obstructive jaundice Endoscopy Endoscopic retrograde cholangiopancreatography

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Integration of Machining and Measuring Processes Using On-Machine Measurement Technology

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厦门大学学报（自然科学版） 2002年第S1期41卷 102-103页

作者： Myeong woo Cho Tae Il Seo dong Sam Park Department of Mechanical Engineering Inha University Technology Development & Assistance Center for SMIs Korea Institute of Industrial TechnologyDepartment of Mechanical Engineering University of Incheon Inchon KoreaBucheon KoreaIncheon Korea

This paper presents an integration methodology for ma chining and measuring processes using OMM (On-Machine Measurement) technology b ased on CAD/CAM/CAI integration concept. OMM uses a CNC machining center as a me asuring station by changing the tools into measuring probes such as touch-type, laser and vision. Although the measurement accuracy is not good compared to tha t of the CMM (Coordinate Measuring Machine), there are distinctive advantages us ing OMM in real situation. In this paper, two topics are handled to show the eff ectiveness of the machining and measuring process integration: (1) inspection pl anning strategy for sculptured surface machining and (2) tool path compensation for profile milling process. For the first topic, as a first step, effective mea suring point locations are determined to obtain optimum results for given sampli ng numbers. Two measuring point selection methods are suggested based on the CAD /CAM/CAI integration concept: (1) by the prediction of cutting errors and (2) by considering cutter contact points to avoid the measurement errors caused by cus ps. As a next step, the TSP (Traveling Salesman Problem) algorithm is applied to minimize the probe moving distance. Appropriate simulations and experiments are performed to verify the proposed inspection planning strategy, and the results are analyzed. For the second topic, a methodology for profile milling error comp ensation is presented by using an ANN (Artificial Neural Network) model trained by the inspection database of OMM system. First, geometric and thermal errors of the machining center are compensated using a closed-loop configuration for the improvement of machining and inspection accuracy. The probing errors are also t aken into account. Then, a specimen workpiece is machined and then the machi ning surface error distribution is measured on the machine using touch-type pro be. In order to efficiently analyze the machining errors, two characteristic err or parameters (W er

关键词： CAD/AM/CAI integration OMM (On-Machine Measurem ent) inspection planning error compensation neural network

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