检索结果-南通市图书馆

Journal of Energy Chemistry 2022年第4期31卷 55-64页

作者： Jie Wang Hong dong Peng Wang Xiao-Lan Fu ning-Shuang Zhang dong-ni zhao Shi-You Li Xiao-Ling Cui School of Petrochemical Technology Lanzhou University of TechnologyLanzhou 730050GansuChina Gansu Key Laboratory of Low-Carbon Energy and Chemical Engineering Lanzhou 730050GansuChina Gansu Engineering Laboratory of Electrolyte Material for Lithium-ion Battery Lanzhou 730050GansuChina

Tris(trimethylsilyl)borate(TMSB) has been intensively studied to improve the performances of lithiumion batteries. However, it is still an interesting issue needed to be resolved for the research on the Li^(+) solvation structure affected by TMSB additive. Herein, the electrochemical tests, quantum chemistry calculations, potential-resolved in-situ electrochemical impedance spectroscopy measurements and surface analyses were used to explore the effects of Li^(+) solvation structure with TMSB additive on the formation of the cathode electrolyte interface(CEI) film in Lini_(0.8)Co_(0.1)Mn_(0.1)O_(2)/Li half cells. The results reveal that the TMSB additive is easy to complex with Li^(+) ion, thus weaken the intermolecular force between Li^(+) ions and ethylene carbonate solvent, which is benefit for the cycle performance. Besides, the changed Li^(+) solvation structure results in a thin and dense CEI film containing compounds with Si–O and B–O bonds which is favorable to the transfer of Li^(+) ions. As a result, the performances of the LNCM811/Li half cells are effectively improved. This research provides a new idea to construct a high-performance CEI film by adjusting the Li^(+) solvation structures.

关键词： Lithium-ion battery Solvation structure Tris(trimethylsilyl)borate Si-containing additive Lini_(0.8)Co_(0.1)Mn_(0.1)O_(2) Cathode electrolyte interface film

Effect of temperature on formation and evolution of solid electrolyte in terphase on Si@Graphite@C anodes

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2022年第1期31卷 190-200,I0006页

作者： Hong dong Jie Wang Peng Wang Hao Ding Ru Song ning-Shuang Zhang dong-ni zhao Li-Juan Zhang Shi-You Li College of Petrochemical Technology Lanzhou University of TechnologyLanzhou 730050GansuChina Gansu Key Laboratory of Low-Carbon Energy and Chemical Engineering Lanzhou 730050GansuChina College of Chemistry and Chemical Engineering Qinghai University for NationalitiesXining 810007QinghaiChina

Studies on the formati on and evolutio n of the solid electrolyte in terface(SEI)film under different ambient temperatures are important to understand the failure behavior of lithium-ion batteries(LIBs).Herein,in-situ electrochemical impedance spectroscopy(EIS)test is performed on the whole discharge process of Si@Graphite@C/Li cell at 0,25 and 55℃,*** with scanning electron microscopy,transmission electron microscopy and X-ray photoelectron spectroscopy characterizations,it is found that the SEI film undergoes a complicated evolution process of pre-formation,self-improvement and gradual decay in succession at 25℃.Besides,due to the dissolution of organo-alkyl lithium at high temperature,the formed film is mainly composed of LiF,Li_(2)CO_(3) and other in organic salts,which helps to decrease the ***,the electrolyte is consumed continuously on the new exposed in terface,leading to the degraded performance of the ***,the dyn amic properties of Li^(+) ions are poor at low temperature,though the migration ability of Li^(+) ions in the solid phase can be improved as the cycle goes ***,the development and application of in-situ EIS tech no logy are expected to become an important means to explain the electrochemical performance of batteries.

关键词： In-situ EIS Solid electrolyte in terphase Formation Evolution Si@Graphite@C anodes

Mechanism of aluminum corrosion in LiFSI-based electrolyte at elevated temperatures

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2021年第5期31卷 1439-1451页

作者： Chun-lei LI Shuang-wei ZENG Peng WANG zhao-juan LI Li YANG dong-ni zhao Jie WANG Hai-ning LIU Shi-you LI College of Petrochemical Technology Lanzhou University of TechnologyLanzhou 730050China CAS Key Laboratory of Comprehensive and Highly Efficient Utilization of Salt Lake Resources Qinghai Institute of Salt LakeChinese Academy of SciencesXining 810008China

Lithium bis(fluorosulfonyl)imide(LiFSI) is a promising replacement for lithium hexafluorosphate due to its excellent properties. A solution to the corrosion of aluminum(Al) current collectors by LiFSI at elevated temperatures is essential. The mechanisms of Al corrosion in LiFSI-based electrolyte at 45 ℃ were studied with density functional theory calculations and spectroscopic investigations. It is found that the irregular, loose and unprotected AlF3 materials caused by the dissolution of co-generated Al(FSI)3 can exacerbate Al corrosion with the increase of temperature. Lithium bis(oxalate)borate(LiBOB) can effectively inhibit the Al corrosion with a robust and protective interphase;this can be attributed to the interfacial interactions between the Al foil and electrolyte. Boron-containing compounds promote the change from AlF3 to LiF, which further reinforces interfacial stability. This work allows the design of an interface to Al foil using LiFSI salt in lithium-ion batteries.

关键词： lithium-ion batteries LiFSI-based electrolyte lithium bis(oxalate)borate(LiBOB) corrosion inhibition elevated temperatures interfacial film

抗苗勒氏管激素评估卵巢储备功能的临床应用现状

在线全文

学校读者我要写书评

暂无评论

生殖与避孕 2016年第8期36卷 648-652页

作者：高姗赵冬妮谭季春中国医科大学附属盛京医院辅助生殖中心沈阳110004

卵巢储备功能指卵巢内存留卵泡的数量和质量,其能间接地反映女性的生育能力。抗苗勒氏管激素(anti-Müllerian hormone,AMH)作为卵巢特异性的生长因子,由颗粒细胞分泌,是预测卵巢储备功能的一个有效指标。血清AMH的水平可以预测卵泡池... 详细信息

卵巢储备功能指卵巢内存留卵泡的数量和质量,其能间接地反映女性的生育能力。抗苗勒氏管激素(anti-Müllerian hormone,AMH)作为卵巢特异性的生长因子,由颗粒细胞分泌,是预测卵巢储备功能的一个有效指标。血清AMH的水平可以预测卵泡池的大小、卵巢的反应性及女性的绝经年龄,同时可以评估癌症患者的卵巢储备功能。但AMH的测定值受到多种因素的影响,存在一定的局限性。

关键词：抗苗勒氏管激素(AMH) 卵巢储备生育能力局限性

Revolutionizing photothermal CO_(2)hydrogenation with ceria-based catalysts

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 30-49页

作者： zhaorui Zhang Xiao Han Junhong Zhang Yunyun dong Jinsheng zhao Qian Xu ingqiang Zhang School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng 252059China Institute for Catalysis Hokkaido UniversityN-21W-10Sapporo 001-0021Japan National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

In the context of achieving carbon neutrality,CO_(2)catalytic conversion technologies are effective in reducing atmospheric CO_(2)concentrations while simultaneously producing renewable *** approach is seen as a viable method for constructing a new carbon cycle,thereby effectively addressing the issue of global *** CO_(2)conversion has recently emerged as a promising research focus due to its high energy utilization efficiency,superior CO_(2)conversion,excellent product selectivity,mild operating conditions,low energy consumption and minimal operating *** oxide(CeO_(2))has been widely used in photothermal catalysis due to its unique chemical properties,particularly when used as a support material with supported metals,creating distinctive interfacial sites for catalytic *** an emerging star support in photothermal CO_(2)conversion,its contributions are equally significant and should not be ***,to our knowledge,there has been no comprehensive review of CeO_(2)applications in catalytic hydrogenation of CO_(2).In this paper,we summarize and discuss CeO_(2)-based materials for photothermal CO_(2)conversion to value-added *** research particularly focuses on the synthesis methods of CeO_(2)-supported catalysts,the history of CeO_(2)in photothermal catalysis,types of photothermal catalytic reactors,unique characterization methods for the photothermal catalysts and the photothermal CO_(2)hydrogenation reactions by CeO_(2)-based *** related to further challenges and future directions for photothermal CO_(2)hydrogenation are also provided.

关键词： CO_(2)neutrality hydrogenation photothermal catalysis ceria C1 chemistry

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3245-3258页

作者： Jiayi Wang Mengke zhao dong Fu Meina Wang Chao Han Zhongyue Lv Liang Wang Jing Liu Stem Cell Clinical Research Center The First Affiliated Hospital of Dalian Medical UniversityDalianLiaoning ProvinceChina Dalian Innovation Institute of Stem Cell and Precision Medicine DalianLiaoning ProvinceChina Institute(College)of Integrative Medicine Dalian Medical UniversityDalianLiaoning ProvinceChina

Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem cell therapy and advancing the frontiers of stem cell-derived *** lays a foundation for the development of potentially potent new treatment modalities for ischemic ***,the precise mechanisms underlying the efficacy and safety of human neural stem cell-derived extracellular vesicles remain unclear,presenting challenges for clinical *** promote the translation of therapy based on human neural stem cell-derived extracellular vesicles from the bench to the bedside,we conducted a comprehensive preclinical study to evaluate the efficacy and safety of human neural stem cell-derived extracellular vesicles in the treatment of ischemic *** found that administration of human neural stem cell-derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal *** human neural stem cell-derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase,mammalian target of rapamycin,and protein kinase B,and these effects were reversed by treatment with a phosphoinositide 3-kinase *** findings suggest that human neural stem cell-derived extracellular vesicles play a neuroprotective role in ischemic stroke through activation of phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling ***,we showed that human neural stem cell-derived extracellular vesicles have a good in vivo safety ***,human neural stem cell-derived extracellular vesicles are a promising potential agent for the treatment of ischemic stroke.

关键词： behavior exosome extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

Single-cell omics: experimental workflow, data analyses and applications

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing zhao Jing-dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2633-2644页

作者： Zhimin Long Chuanhua Ge Yueyang zhao Yuanjie Liu Qinghua Zeng Qing Tang Zhifang dong Guiqiong He Institute of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqingChina Department of Anatomy Chongqing Medical UniversityChongqingChina Department of Physiology Chongqing Medical UniversityChongqingChina Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina National Clinical Research Center for Child Health and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque ***,resto ring normal lysosomal function and rebalancing lysosomal acidification in neurons in the brain may be a new treatment strategy for Alzheimer's *** acetylation/deacetylation plays a central role in lysosomal ***,we show that inhibiting the classic microtubule deacetylase histone deacetylase 6 with an histone deacetylase 6 shRNA or thehistone deacetylase 6 inhibitor valproic acid promoted lysosomal reacidification by modulating V-ATPase assembly in Alzheimer's *** rthermore,we found that treatment with valproic acid markedly enhanced *** clearance of amyloid-βaggregates,and ameliorated cognitive deficits in a mouse model of Alzheimer's *** findings demonstrate a previously unknown neuroprotective mechanism in Alzheimer's disease,in which histone deacetylase 6 inhibition by valproic acid increases V-ATPase assembly and lysosomal acidification.

关键词： Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPase

互联网慢病管理模式对糖尿病患者血糖控制的影响

在线全文

学校读者我要写书评

暂无评论

临床医学研究与实践 2019年第19期4卷 153-154页

作者：董朝妮方丹杜梅梅延安大学咸阳医院

目的研究互联网慢病管理模式对糖尿病患者血糖控制的影响。方法选取我院收治的60例2型糖尿病患者为研究对象,采用随机数字表法将其分为观察组(常规慢病管理+互联网干预)和对照组(常规慢病管理),每组30例。比较两组患者的血糖控制情况。... 详细信息

目的研究互联网慢病管理模式对糖尿病患者血糖控制的影响。方法选取我院收治的60例2型糖尿病患者为研究对象,采用随机数字表法将其分为观察组(常规慢病管理+互联网干预)和对照组(常规慢病管理),每组30例。比较两组患者的血糖控制情况。结果出院后第1、2、3个月,观察组患者FBG、PBG水平显著低于对照组(P<0.05)。出院后第3个月,两组患者的HbA1c水平均降低,且观察组显著低于对照组(P<0.05)。结论通过互联网慢病管理模式,可以提高患者对糖尿病的自我管理,达到有效控制血糖的目的。

关键词：互联网慢病管理糖尿病血糖控制

重症急性胰腺炎经鼻空肠管肠内营养治疗的作用分析

在线全文

学校读者我要写书评

暂无评论

中国医药导刊 2015年第9期17卷 910-911页

作者：蔡斌董朝妮代海鹏陕西省延安大学咸阳医院肝胆外科咸阳712000 陕西省咸阳西橡医院普通外科咸阳712000

目的:探析重症急性胰腺炎经鼻空肠管肠内营养治疗的临床效果。方法:将我院收治的重症急性胰腺炎患者84例随机分为两组,其中给予对照组常规治疗,观察组运用经鼻空肠管肠内营养治疗,对比两组治疗效果。结果:观察组的各项指标改善均优于对... 详细信息

目的:探析重症急性胰腺炎经鼻空肠管肠内营养治疗的临床效果。方法:将我院收治的重症急性胰腺炎患者84例随机分为两组,其中给予对照组常规治疗,观察组运用经鼻空肠管肠内营养治疗,对比两组治疗效果。结果:观察组的各项指标改善均优于对照组,组间对比差异有统计学意义(P<0.05)。结论:临床上运用经鼻空肠管肠内营养治疗重症急性胰腺炎,不仅安全性高,还能降低死亡率,促进患者康复。

关键词：重症急性胰腺炎经鼻空肠管肠内营养