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Synthesis and Characterization of a Novel Liquid Crystalline Chitin Quaternary Ammonium Chitosan Salt

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Chemical Research in Chinese Universities 2003年第4期19卷 512-515页

作者： RUAN Yong-hong dong yan-ming WU ming-shui ZENG Man-qing WANG Shui-ju Department of Materials Science and Engineering Xiamen UniversityXiamen 361005P.R.China

N -Butyl chitosan(NBCS) derivatives were prepared by introducing butyl groups into the amine groups of chitosan via Schiff base intermediates. The quaternization of NBCS was carried out by using ethyl iodide to produce water-soluble cationic polyelectrolytes. The degree of the substitution of the products was measured by means of the electron spectroscopy for a successful chemical analysis. The quaternary ammonium chitosan salt(QACS) was proved to be a novel cholesteric liquid crystalline chitin, by means of the polarized optical microscopy and the circular dichroism spectropolarimetry. The critical mass fraction of the QACS/formic acid solution forming a lyotropic liquid crystal phase was 50%, which was almost the same as that of the NBCS/formic acid solution, but much higher than that of the chitosan in the same solvent.

关键词： Quaternary ammonium chitosan Cholesteric liquid crystal ESCA CD spectropolarimetry

Fast and Error-Bounded Space-Variant Bilateral Filtering

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Journal of Computer Science & Technology 2019年第3期34卷 550-568页

作者： Meng-Ke Yuan Long-Quan Dai dong-ming yan Li-Qiang Zhang Jun Xiao Xiao-Peng Zhang National Laboratory of Pattern Recognition Institute of AutomationChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Computer Science and Technology Nanjing University of Science and TechnologyNanjing 210094China State Key Laboratory of Remote Sensing Science School of GeographyBeijing Normal UniversityBeijing 100875China

The traditional space-invariant isotropic kernel utilized by a bilateral filter(BF)frequently leads to blurry edges and gradient reversal artifacts due to tlie existence of a large amount of outliers in the local averaging ***,the efficient and accurate cstiinatioii of space-variant k(4rnels which adapt to image structures,and the fast realization of the corresponding space-variant bilateral filtering are challenging *** address these problems,we present a space-variant BF(SVBF).and its linear time and error-bounded acceleration ***,we accurately estimate spacevariant,anisotropic kernels that vary with image structures in linear time through structure tensor and mininnini spanning ***,we perform SVBF in linear time using two error-bounded approximation methods,namely,low-rank tensor approximation via higher-order singular value decomposition and exponential sum *** proposed SVBF can efficiently achieve good edge-preserving *** validate the advantages of the proposed filter in applications including:image denoising,image enhancement,and image focus *** results(leinonstrate that our fast and error-bounded SVBF is superior to state-of-the-art methods.

关键词： error-bounded acceleration edge-aware smoothing space-variant bilateral filtering

Drying Shrinkage of Cement-Based Materials Under Conditions of Constant Temperature and Varying Humidity

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Journal of China University of Mining and Technology 2007年第3期17卷 428-431页

作者： MA Bao-guo WEN Xiao-dong WANG ming-yuan yan Jia-jia Gao Xiao-jian Key Laboratory for Silicate Materials Science and Engineering of Ministry of Education Wuhan University of Technology Wuhan Hubei 430070 China

Currently,deformations along the central axis of specimens were usually measured under fixed environmental conditions. Seldom were the effects of environmental factors on the drying-shrinkage deformation of cement-based ma-terial considered. For this paper,the drying-shrinkage deformation at different w/b ratios and different additions to mor-tars was investigated under different environments at a temperature of 20 ℃ and humidity ranging from 100% to 50%. The specimens were cured in water for 28 days before measurement. The results illustrate that mortar shows much less shrinkage under various drying conditions when a lower w/b ratio is adopted. With a decrease in relative humidity the speed of drying-shrinkage becomes gradually lower. The addition of silica fume reduces the drying-shrinkage of mortar under higher relative humidity,because the pore structure of mortar with silica fume becomes more refined. The addi-tion of fly ash increases the total porosity and the volume of coarse pores in the mortar. The drying-shrinkage of mortar under different conditions increases with the addition of more of fly ash.

关键词： humidity variation volume deformation pore structure

Long non-coding RNA MEG3 regulates autophagy after cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2022年第4期17卷 824-831页

作者： Tian-Hao Li Hong-Wei Sun Lai-Jun Song Bo yang Peng Zhang dong-ming yan Xian-Zhi Liu Yu-Ru Luo Department of Neurosurgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina

Severe cerebral ischemia/reperfusion injury has been shown to induce high-level autophagy and neuronal ***,it is extremely important to search for a target that inhibits autophagy *** non-coding RNA MEG3 participates in ***,it remains unclear whether it can be targeted to regulate cerebral ischemia/reperfusion *** results revealed that in oxygen and glucose deprivation/reoxygenation-treated HT22 cells,MEG3 expression was obviously upregulated,and autophagy was increased,while knockdown of MEG3 expression greatly reduced ***,MEG3 bound mi R-181 c-5 p and inhibited its expression,while mi R-181 c-5 p bound to autophagy-related gene ATG7 and inhibited its *** experiments revealed that mir-181 c-5 p overexpression reversed the effect of MEG3 on autophagy and ATG7 expression in HT22 cells subjected to oxygen and glucose deprivation/*** vivo experiments revealed that MEG3 knockdown suppressed autophagy,infarct volume and behavioral deficits in cerebral ischemia/reperfusion *** findings suggest that MEG3 knockdown inhibited autophagy and alleviated cerebral ischemia/reperfusion injury through the mi R-181 c-5 p/ATG7 signaling ***,MEG3 can be considered as an intervention target for the treatment of cerebral ischemia/reperfusion *** study was approved by the Animal Ethics Committee of the First Affiliated Hospital of Zhengzhou University,China(approval ***20190538)on January 4,2019.

关键词： ATG7 autophagy cerebral infarction cerebral ischemia/reperfusion injury long non-coding RNA miR-181c-5p neuron oxygen and glucose deprivation/reoxygenation

活性瓷釉涂层钢筋及钢纤维增强混凝土板动、静力学特性研究（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2016年第5期17卷 366-377页

作者： dong-ming yan Shi-kun CHEN Gen-da CHEN Jason BAIRD School of Civil and Architectural Engineering Zhejiang University Department of Civil Architectural and Environmental Engineering Missouri University of Science and Technology

目的:活性瓷釉涂层能够显著增强钢筋的防腐蚀能力,同时明显提升钢筋与混凝土的粘结力。通过对活性瓷釉涂层钢筋以及钢纤维增强混凝土板在动、静力荷载作用下的承载力、变形特性以及破坏特征的研究,为活性瓷釉涂层技术在钢筋混凝土结构... 详细信息

目的:活性瓷釉涂层能够显著增强钢筋的防腐蚀能力,同时明显提升钢筋与混凝土的粘结力。通过对活性瓷釉涂层钢筋以及钢纤维增强混凝土板在动、静力荷载作用下的承载力、变形特性以及破坏特征的研究,为活性瓷釉涂层技术在钢筋混凝土结构中的应用奠定理论基础。创新点:1.对活性瓷釉涂层钢筋混凝土板的动、静力学性能进行系统研究;2.探究活性瓷釉钢纤维在混凝土结构中的作用机理。方法:1.通过对活性瓷釉涂层钢筋混凝土板进行爆炸实验(图3),揭示活性瓷釉涂层钢筋混凝土结构的动力破坏特征(图5和6);2.通过对活性瓷釉涂层钢筋混凝土板进行静力实验(图4),研究在"点"荷载和"线"荷载作用下混凝土板的力学性能;3.通过分析钢纤维在钢筋混凝土结构中的传力机理,提出活性瓷釉涂层钢纤维在钢筋混凝土结构中的设计方法(图13)。结论:1.活性瓷釉涂层能够显著改善钢筋在混凝土结构中的传力性能;在动力荷载作用下,涂层钢筋混凝土结构的破坏程度明显减轻。2.活性瓷釉涂层能够显著改善钢筋混凝土结构的变形特性,大大增强其耗能能力。3.采用活性瓷釉涂层的钢纤维,其纤维长度可适当减小。

关键词：活性瓷釉涂层爆炸荷载破坏特征钢纤维

Blast response of full-size concrete walls with chemically reactive enamel （CRE）-coated steel reinforcement

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2016年第9期17卷 689-701页

作者： dong-ming yan Hua-wei YIN Cheng-lin WU yan-long LI Jason BAIRD Gen-da CHEN School of Civil and Architectural Engineering Zhejiang University Hangzhou 310058 China College of Civil Engineering Hunan University Changsha 410082 China Department of Civil Architectural and Environmental Engineering Missouri University of Science and Technology Rolla 654009 USA State Key Laboratory Base of Eco-Hydraulic Engineering in Arid Area Xi'an University of Technology Xi'an 710048 China Rock Mechanics and Explosives Missouri University of Science and Technology Rolla 654009 USA Center for Infrastructure Engineering Studies Missouri University of Science and Technology Rolla 654009 USA

In this study, two full-size concrete wails were tested and analyzed to demonstrate the effectiveness of a chemically reactive enamel （CRE） coating in improving their mechanical behavior under blast loading： one with CRE-coated rebar and the other with uncoated rebar. Each wall was subjected in sequence to four explosive loads with equivalent 2, 4, 6-trinitrotoluene （TNT） charge weights of 1.82, 4.54, 13.6, and 20.4 kg. A finite element model of each wall under a close-in blast load was developed and validated with pressure and strain measurements, and used to predict rebar stresses and concrete surface sWain distributions of the wall. The test results and visual inspections consistently indicated that, compared with the barrier wall with uncoated reinforcement, the wall with CRE-coated rebar has fewer concrete cracks on the front and back faces, more effective stress transfers from concrete to steel rebar, and stronger connections with its concrete base. The concrete surface strain distributions predicted by the model under various loading conditions are in good agreement with the crack patterns observed during the tests.

关键词： Chemically reactive enamel (CRE) coating Blast loading Crack pattern Bond strength Finite element model

Mutation of DNA polymerase p in esophageal carcinoma of different regions

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World Journal of Gastroenterology 2005年第30期11卷 4618-4622页

作者： Guo-Qiang Zhao Tao Wang Qin Zhao Qin Zhao, Hong-yan yang, Xiao-Hui Tan, Zi-ming dong Hong-yan yang Xiao-Hui Tan Zi-ming dong Basic Medical College Zhengzhou University Zhengzhou 450052 Henan Province China

AIM： To observe the variation of DNA polymerase β （polβ） in esophageal carcinoma. METHODS： Thirty specimens containing adjacent normal epithelial tissues were collected from patients in Linzhou region （a high risk area for esophageal squamous carcinoma） and 25 specimens were from a non-high risk area. Total RNA was extracted from the samples and reverse transcription polymerase chain reaction （RT-PCR） was performed. PCR products were cloned and sequenced to investigate the po1β gene with DNASIS and OMIGA. Statistical significance was evaluated using the X^2 test. RESULTS： High-inddence area group： Polβ gene variation was detected in 13 of 30 esophageal carcinoma tissue specimens, and only one variation was found in 30 corresponding adjacent normal tissue specimens. Non high-incidence area group： po1β gene variation was detected in 5 of 25 esophageal carcinoma tissue specimens, and no variation was found in 25 corresponding adjacent normal tissue specimens. The incidence of po1β gene variation observed in the high-incidence area group was significantly higher than in the non-high incidence area group. Two mutation hot spots （454-466 and 648-670 nt） and a 58 bp deletion （177-234 nt） were found. CONCLUSION： Variations of polβ perform different functions between the high-incidence areas and the other areas, and may play a more important role in the high-incidence areas.

关键词： DNA polymerase β Esophageal carcinoma Gene mutation

An Artificial Intelligence‑Assisted Flexible and Wearable Mechanoluminescent Strain Sensor System

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Nano-Micro Letters 2025年第3期17卷 217-231页

作者： yan dong Wenzheng An Zihu Wang dongzhi Zhang College of Control Science and Engineering China University of Petroleum(East China)Qingdao 266580People’s Republic of China

The complex wiring,bulky data collection devices,and difficulty in fast and on-site data interpretation significantly limit the practical application of flexible strain sensors as wearable *** tackle these challenges,this work develops an artificial intelligenceassisted,wireless,flexible,and wearable mechanoluminescent strain sensor system(AIFWMLS)by integration of deep learning neural network-based color data processing system(CDPS)with a sandwich-structured flexible mechanoluminescent sensor(SFLC)*** SFLC film shows remarkable and robust mechanoluminescent performance with a simple structure for easy *** CDPS system can rapidly and accurately extract and interpret the color of the SFLC film to strain values with auto-correction of errors caused by the varying color temperature,which significantly improves the accuracy of the predicted strain.A smart glove mechanoluminescent sensor system demonstrates the great potential of the AIFWMLS system in human gesture ***,the versatile SFLC film can also serve as a encryption *** integration of deep learning neural network-based artificial intelligence and SFLC film provides a promising strategy to break the“color to strain value”bottleneck that hinders the practical application of flexible colorimetric strain sensors,which could promote the development of wearable and flexible strain sensors from laboratory research to consumer markets.

关键词： Mechanoluminescent Strain sensor Flexible Deep learning Wireless

Turbulent Agglomeration of Microparticles in a Cylinder Wake Flow Using LES-DEM:Focusing on the Effect of the Reynolds Number

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Journal of Thermal Science 2025年第1期34卷 34-49页

作者： WANG Shuang MU Lin LI Xue XIE Jun dong ming School of Energy and Power Engineering Dalian University of Technology School of Optical Information and Energy Engineering Wuhan Institute of Technology School of Energy and Environment Shenyang Aerospace University

Turbulent agglomeration is viewed as a promising technology for enhancing fine particle removal *** better understand particle transport,agglomeration behaviors,and fluid-particle interactions,we numerically explored these phenomena under cylindrical vortex wake influence using a coupled large eddy simulation and discrete element method（LES-DEM） *** validity of the LES approach was verified by comparison with available direct numerical simulation（DNS） *** adopted the Johnson-Kendall-Roberts（JKR） contact model for particle-particle *** particle dispersion and agglomeration characteristics of particles with different diameters（dp=2-20 μm） in the laminar and transition of shear layer（TrSL） flow regimes were *** particles were concentrated at the vortex centers,while larger particles accumulated around the *** agglomeration efficiency exhibited an M-shaped profile spanwise（y-direction）.With increasing Reynolds number,the agglomeration efficiency and turbulence intensity *** particle agglomeration efficiency peaks at a certain Reynolds ***,at higher Reynolds numbers,reducing the residence time of particles in the flow field decreases the agglomeration efficiency.

关键词： discrete element method large eddy simulation microparticle particle agglomeration