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Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia Chen Ruixin Yao mei Tian Jian Wang Fengtao Liu Chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET Center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(Shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of *** review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest *** conducted a thorough literature search using reputable databases such as PubMed and Web of *** criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical *** findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting ***,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo *** validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic *** summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

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Isolation of lignosulfonate with low polydispersity index

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Chinese Chemical Letters 2010年第12期21卷 1479-1481页

作者： Xin Ping Ouyang Pan Zhang Chun mei Tan Yong Hong deng dong Jie Yang Xue Qing Qiu School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510640China

Lignosulfonate with low polydispersity index of 1.178-1.210 was isolated by gel column chromatography of Sephacryl S-100 eluted with 0.2 mol/L of NaNO3 aqueous solution,whereas nearly monodisperse ligosulfonate fraction with polydispersity of 1.0(57 can be obtained after chromatographic separation *** method provides an available approach to investigate the structure and characteristics of lignosulfonate.

关键词： Lignosulfonate Sephacryl Chromatographic separation

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In vitro Transient Expression System of Latex C-serum was used for Analysis of Hevein Promoter in Response to Abscisic Acid in Hevea brasiliensis

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Journal of Integrative Plant Biology 2008年第3期50卷 338-344页

作者： Xiao-Wen Fei Xiao-dong deng Institute of Tropical Bioscience and Biotechnology Chinese Agricultural Academy for Tropical Crops Haikou 571101 China Department of Biochemistry Hainan Medical College Haikou 571101 China

Hevein has been found to be an essential element in coagulation of rubber particles in latex of rubber trees. In a previous study, we cloned a 1 241-bp fragment of a 5＇ upstream region of the hevein gene by genome walking. This fragment was analyzed by a 5＇ end nested deletion method in the present study, fused with a uidA （gus） gene to produce a series of tested constructs, which were transferred into C-serum of latex and the Gus activities were detected. Results showed that the fragment from -749 to -292 was sufficient for expression of gus gene in latex, and the fragment from -292 to -168 was crucial in response to abscisic acid inducement. In a transient transgenic test of rubber leaf with particle bombardment, construct Hev749 conferred gus-specific expression in veins, in which the latex tubes mainly distributed. This implies that the fragment from -749 to -292 was laticiferous-specific.

关键词： abscisic acid gus (beta-glucuronidase) gene hevein promoter rubber tree (Hevea brasiliensis)

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IL-21 acts as a promising therapeutic target in systemic lupus erythematosus by regulating plasma cell differentiation

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Cellular & Molecular Immunology 2015年第1期12卷 31-39页

作者： Xiao-mei deng Shang-Xue Yan Wei Wei Institute of Clinical Pharmacology of Anhui Medical University Key Laboratory of Anti-inflammatory and Immune Medicine Ministry of Education HefeiChina

Plasma cells, which secrete auto-antibodies, are considered to be the arch-criminal of autoimmune diseases such as systemic lupus erythematosus, but there are many cytokines involved in inducing the differentiation of B-cell subsets into plasma cells. Here, we emphasize IL-21, which has emerged as the most potent inducer of plasma cell differentiation. In this review, we focused on the promoting effects of IL-21 on plasma cell differentiation and discuss how these effects contribute to B cell-mediated autoimmune disease.

关键词： Bcl-6 Blimp-1 IL-21 plasma cell systemic lupus erythematosus

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Bifurcations and Chaos in Duffng Equation with Damping and External Excitations

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Acta Mathematicae Applicatae Sinica 2014年第2期30卷 483-504页

作者： mei-xiang CAI Jian-ping YANG Jin deng Institute of Mathematics and Physics Central South University of Forestry and Technology College of Science China Agriculture University Department of Mathematics and Physics Hunan Institute of Engineering

Duffing equation with damping and external excitations is investigated. By using Melnikov method and bifurcation theory, the criterions of existence of chaos under periodic perturbations are obtained. By using second-order averaging method, the criterions of existence of chaos in averaged system under quasi-periodic perturbations for Ω = nω ＋ εσ, n = 2,4,6 （where σ is not rational to ω） are investigated. However, the criterions of existence of chaos for n = 1, 3, 5, 7 - 20 can not be given. The numerical simulations verify the theoretical analysis, show the occurrence of chaos in the averaged system and original system under quasi- periodic perturbation for n = 1, 2, 3, 5, and expose some new complex dynamical behaviors which can not be given by theoretical analysis. In particular, the dynamical behaviors under quasi-periodic perturbations are different from that under periodic perturbations, and the period-doubling bifurcations to chaos has not been found under quasi-periodic perturbations.

关键词： Duffing equation Melnikov method second-order averaging method chaos

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A Property of g-probabilities

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Acta Mathematicae Applicatae Sinica 2010年第4期26卷 567-574页

作者： dong-mei Guo Zeng-jing Chen School of Economics Central University of Finance and EconomicsBeijing 100081China School of Mathematics Shandong UniversityShandong 250100China Department of Financial Engineering Ajou UniversityKorea

Most work on capacities has focused on the 2-alternating and sub *** this paper we consider the capacities-g-probabilities derived from peng＇s *** g satisfies some conditions,we show that the g-probabilities fail to ... 详细信息

关键词： BSDEs g-expectations g-probabilities 2-alternating capacities sub 2-alternating capacities

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论“慎捕”的法规范控制体系及实践问题破解

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武汉大学学报（哲学社会科学版） 2025年第1期78卷 172-184页

作者：董坤中国社会科学院法学研究所中国社会科学院大学北京100720

历次修法中涉及逮捕的制度机制的演进轨迹和条文变化的内在逻辑表明,为实现“慎捕”目标,《中华人民共和国刑事诉讼法》(以下简称《刑事诉讼法》)已初步构筑起一套结构严谨、衔接有序、层次分明的关于逮捕权的法规范控制体系。该体系在... 详细信息

历次修法中涉及逮捕的制度机制的演进轨迹和条文变化的内在逻辑表明,为实现“慎捕”目标,《中华人民共和国刑事诉讼法》(以下简称《刑事诉讼法》)已初步构筑起一套结构严谨、衔接有序、层次分明的关于逮捕权的法规范控制体系。该体系在事前的权力配置阶段“两次分离”逮捕权,以具体社会危险性评估为重心改造逮捕要件;在事中的权力行使阶段以“兼听则明”为原则设计了充分听取控辩双方意见的审查逮捕机制;在事后的权力制约阶段要求检察院、法院及时纠正撤销错捕决定,释放犯罪嫌疑人。从司法办案的角度来看,现有的法规范控制体系在规则制定和程序执行时仍有不足和缺漏,如逮捕权分离不彻底,控辩意见“兼听”机制保障不充分,径行逮捕条件设计机械、不周延,当事人对错捕的救济途径缺失等。本轮《刑事诉讼法》修改应坚持“实践—规范”的互动逻辑,关注司法实践,将解决和弥补逮捕中的权力运行失范和权利保障不足等现实问题作为修法方向,破难题、开新局,不断推动中国刑事诉讼法治现代化进程。

关键词：慎捕法规范控制体系径行逮捕权利保障《刑事诉讼法》修改

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Supernova β^- decay of nuclides ^(53)Fe,^(54)Fe,^(55)Fe and ^(56)Fe in strongly screened plasma

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Research in Astronomy and Astrophysics 2018年第1期18卷 95-100页

作者： Jing-Jing Liu dong-mei Liu College of Electronic and Communication Engineering Hainan Tropical Ocean University

Electron screening has strong effects on electron energy and threshold energy of the beta decay *** this paper,we study β~-decay rates of some iron *** beta decay rates increase by about two orders of magnitude due to electron *** screened beta decay rates due to Q-value correction are more than one order of magnitude higher than those without Q-value correction.

关键词： physical data and processes:nuclear reactions nucleosynthesis abundances stars:supernovae

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Magnetron sputtered nickel oxide with suppressed interfacial defect states for efficient inverted perovskite solar cells

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Journal of Energy Chemistry 2025年第1期100卷 348-355页

作者： Guoqiang Ma Qin Tan Zhaoning Li Jingwei Xiu Jiafeng Wang Tianle Cheng dong He Qiang Sun Xuhang Ma Francesco Lamberti Zhubing He Department of Materials Science and Engineering Institute of Innovative Materials (I2M) Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG)Southern University of Science and Technology (SUSTech) Core Research Facilities Southern University of Science and Technology Department of Chemical Sciences Department of Industrial Engineering University of Padova

Widely used spin-coated nickle oxide （NiOx） based perovskite solar cells often suffer from severe interfacial reactions between the NiOxand adjacent perovskite layers due to surface defect states,which inherently impair device performance in a long-term view,even with surface molecule *** this study,we developed high-quality magnetron-sputtered NiOxthin films through detailed process optimization,and compared systematically sputtered and spin-coated NiOxthin film surfaces from materials to *** sputtered NiOxfilms exhibit improved crystallinity,smoother surfaces,and significantly reduced Ni3+or Ni vacancies compared to their spin-coated ***,the interface between the perovskite and sputtered NiOxfilm shows a substantially reduced density of defect *** solar cells （PSCs） fabricated with our optimally sputtered NiOxfilms achieved a high power conversion efficiency （PCE） of up to 19.93%and demonstrated enhanced stability,maintaining 86.2% efficiency during 500 h of maximum power point tracking under one standard sun ***,with the surface modification using (4-(2,7-dibromo-9,9-dimethylacridin-10（9H）-yl)butyl)p hosphonic acid （DMAcPA）,the device PCE was further promoted to 23.07%,which is the highest value reported for sputtered NiOxbased PSCs so far.

关键词： Nickle oxide Magnetron sputter Defect Stability Perovskite solar cell

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Revolutionizing photothermal CO_(2)hydrogenation with ceria-based catalysts

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Nano Research 2025年第1期18卷 30-49页

作者： Zhaorui Zhang Xiao Han Junhong Zhang Yunyun dong Jinsheng Zhao Qian Xu ingqiang Zhang School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng 252059China Institute for Catalysis Hokkaido UniversityN-21W-10Sapporo 001-0021Japan National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

In the context of achieving carbon neutrality,CO_(2)catalytic conversion technologies are effective in reducing atmospheric CO_(2)concentrations while simultaneously producing renewable *** approach is seen as a viable method for constructing a new carbon cycle,thereby effectively addressing the issue of global *** CO_(2)conversion has recently emerged as a promising research focus due to its high energy utilization efficiency,superior CO_(2)conversion,excellent product selectivity,mild operating conditions,low energy consumption and minimal operating *** oxide(CeO_(2))has been widely used in photothermal catalysis due to its unique chemical properties,particularly when used as a support material with supported metals,creating distinctive interfacial sites for catalytic *** an emerging star support in photothermal CO_(2)conversion,its contributions are equally significant and should not be ***,to our knowledge,there has been no comprehensive review of CeO_(2)applications in catalytic hydrogenation of CO_(2).In this paper,we summarize and discuss CeO_(2)-based materials for photothermal CO_(2)conversion to value-added *** research particularly focuses on the synthesis methods of CeO_(2)-supported catalysts,the history of CeO_(2)in photothermal catalysis,types of photothermal catalytic reactors,unique characterization methods for the photothermal catalysts and the photothermal CO_(2)hydrogenation reactions by CeO_(2)-based *** related to further challenges and future directions for photothermal CO_(2)hydrogenation are also provided.

关键词： CO_(2)neutrality hydrogenation photothermal catalysis ceria C1 chemistry

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