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Effects of physical rehabilitation interventions in COVID-19 patients following discharge from hospital:A systematic review

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Journal of Integrative Medicine 2023年第2期21卷 149-158页

作者： Masoud Rahmati Mahdieh Molanouri Shamsi Wongi Woo Ai Koyanagi Seung Won Lee dong keon Yon Jae Il Shin Lee Smith Department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan University*** KhoramabadIran Department of Physical Education&Sport Sciences Faculty of HumanitiesTarbiat Modares University*** TehranIran Department of Thoracic and Cardiovascular Surgery Yonsei University College of MedicineGangnam Severance HospitalGangnam-guSeoul 06273Republic of Korea Research and Development Unit Parc Sanitari Sant Joan de DéuSant Boi de Llobregat08830 BarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Barcelona 08010Spain Department of Precision Medicine Sungkyunkwan University School of MedicineSuwon 16419Republic of Korea Medical Science Research Institute Kyung Hee UniversitySeoul 02447Republic of Korea Department of Pediatrics Kyung Hee University Medical CenterKyung Hee UniversitySeoul 02447Republic of Korea Department of Pediatrics College of MedicineYonsei UniversitySeoul 03722Republic of Korea Centre for Health Performanceand WellbeingAnglia Ruskin UniversityCambridge CB11PTUK

Background:Hospitalized patients recovering from coronavirus disease 2019(COVID-19)may experience disability and suffer from significant physical and mental impairment requiring physical rehabilitation following their discharge.However,to date,no attempt has been made to collate and synthesize literature in this area.Objective:This systematic review examines the outcomes of different physical rehabilitation interventions tested in COVID-19 patients who were discharged from hospital.Search strategy:A systematic search of MEDLINE/PubMed,CINAHL,Scopus and medRxiv was conducted to identify articles published up to March 2022.Inclusion criteria:This systematic review included studies of outpatient rehabilitation programs for people recovering from COVID-19 who received physical activity,exercise,or breathing training to enhance or restore functional capacity,pulmonary function,quality of life,and mental health or function.Data extraction and analysis:Selection of included articles,data extraction,and methodological quality assessments were conducted by two review authors respectively,and consensus was reached through discussion and consultation with a third reviewer.Finally,we review the outcomes of studies based on four categories including:(1)functional capacity,(2)pulmonary function,(3)quality of life,and(4)mental health status.Results:A total of 7534 titles and abstracts were screened;10 cohort studies,4 randomized controlled trials and 13 other prospective studies involving 1583 patients were included in our review.Early physical rehabilitation interventions applied in COVID-19 patients who were discharged from the hospital improved multiple parameters related to functional capacity,pulmonary function,quality of life and mental health status.Conclusion:Physical rehabilitation interventions may be safe,feasible and effective in COVID-19 patients discharged from the hospital,and can improve a variety of clinically relevant outcomes.Further studies are warranted to determine the underlying mechanisms.

关键词： COVID-19 Physical activity Exercise Rehabilitation Systematic review

Hydrodynamics of air-kerosene bubble column under elevated pressure in homogeneous flow regime

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Chinese Journal of Chemical Engineering 2021年第5期34卷 190-202页

作者： Bay Van Tran Son Ich Ngo Young-Il Lim keon Bae dong Hyun Lee Kang-Seok Go Nam-Sun Nho Center of Sustainable Process Engineering(CoSPE) Department of Chemical EngineeringHankyong National UniversityGyeonggi-doAnseong-siJungang-ro 32717579Republicof Korea School of Chemical Engineering Sungkyunkwan University2066 Seobu-roJanganSuwon 16419Republic of Korea Center for Convergent Chemical Process(CCP) 141 Gajeong-roYuseong-guDaejeon 34114Republic of Korea

A multiphase computational fluid dynamics(CFD)model coupled with the population balance equation(PBE)was developed in a homogeneous air-kerosene bubble column under elevated pressure(P).The specific pressure drop(ΔP/L),gas holdup(α_(G)),and Sauter mean diameter(d_(32))were experimentally measured in the bubble column with 1.8 m height and 0.1 m inner diameter,which was operated at a superficial gas velocity of 12.3 mm·s^(-1),and P=1-35 bar(1 bar=10^(5) Pa).A modified drag coefficient model was proposed to consider the effect of bubble swarm and pressure on hydrodynamics of the bubble column.The Luo breakage model was modified to account for liquid density,viscosity,surface tension and gas density.TheΔP/L,α_(G),and d_(32) obtained from the CFD model were compared with experimental data,and the gas density-dependent parameters of the CFD model were identified.With increasing P from 1 to 35 bar,theα_(G) varied from 5.4%to 7.2% and the d32 decreased from 2.3 to 1.5 mm.The CFD-PBE model is applicable to predict hydrodynamics of pressurized bubble columns for gas-organic liquid in the homogeneous regime.

关键词： Bubble column Air-kerosene High pressure Homogenous regime Computational fluid dynamics (CFD) Population balance equation (PBE)

Study on the Wiping Gas Jet in Continuous Galvanizing Line

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Journal of Thermal Science 2011年第3期20卷 242-247页

作者： Yong-Hun kweon Heuy-dong Kim POSCO Technical Research Laboratories 699 Gumho-dong GwangyangJeonnam 545-090 Korea School of Mechanical Engineering Andong National UniversityAndong 760-749 Korea

In the continuous hot-dip galvanizing process, the gas-jet wiping is used to control the coating thickness of moving steel strip. The high speed gas-jet discharged from the nozzle slot impinges on the strip, and at this moment, wipes the liquid coating layer dragged by a moving strip. The coating thickness is generally influenced on the flow characteristics of wiping gas-jet such as the impinging pressure distribution, pressure gradient and shear stress distribution on the surface of strip. The flow characteristics of wiping gas-jet mentioned above depends upon considerably both the process operating conditions such as the nozzle pressure, nozzle-to-strip distance and line speed, and the geometry of gas-jet wiping apparatus such as the height of nozzle slot. In the present study, the effect of the geometry of nozzle on the coating thickness is investigated with the help of a computational fluid dynamics method. The height of nozzle slot is varied in the range of 0.6mm to 1.7mm. A finite volume method (FVM) is employed to solve two-dimensional, steady, compressible Navier-Stokes equations. Based upon the results obtained, the effect of the height of nozzle slot in the gas-jet wiping process is discussed in detail. The computational results show that for a given standoff distance between the nozzle to the strip, the effective height of nozzle slot exists in achieving thinner coating thickness.

关键词：气体喷射镀锌生产线 Stokes方程喷嘴压力涂层厚度几何形状计算结果连续热镀锌

Comparative efficacy and optimal duration of first-line antibiotic regimens for acute otitis media in children and adolescents:a systematic review and network meta-analysis of 89 randomized clinicaltrials

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World Journal of Pediatrics 2024年第3期20卷 219-229页

作者： Min Seo Kim Jae Han Kim Seohyun Ryu Seung Won Lee dong keon Yon Eunyoung Kim Ai Koyanagi Elena Dragioti Jae Il Shin Lee Smith Samsung Advanced Institute forHealth Sciences&Technology(SAIHST) Samsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea Yonsei University Collegeof Medicine SeoulRepublicof Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonRepublic of Korea Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulRepublic of Korea Evidence-Based Research Laboratory Department of Clinical Pharmacy and Pharmaceutical CareCollege of PharmacyChung-Ang UniversitySeoulRepublic of Korea Parc Sanitari Sant Joan de Deu/CIBERSAM/ISCIII Universitat de BarcelonaFundacio Sant Joan de Déu.Sant Boi de LlobregatBarcelonaSpain ICREA Pg.Lluis Companys 23BarcelonaSpain Pain and Rehabilitation Centre and Department of Medical and Health SciencesLinkoping University58185 LinkopingSweden Department of Pediatrics Yonsei University College of MedicineYonsei-ro 50Seodaemun-gu8044Seoul 03722Republic of Korea Centre for Health Performanceand WellbeingAnglia Ruskin UniversityCambridge CB11PTUK Research Laboratory Psychology of Patients Families&Health ProfessionalsDepartment of NursingSchool of Health SciencesUniversity of IoanninaIoannina 45500Greece

Introduction Antibiotic use for acute otitis media(AOM)is one of the major sources of antimicrobial resistance.However,the effective minimal antibiotic duration for AOM remains unclear.Moreover,guidelines often recommend broad ranges(5-10 days)of antibiotic use,yet the clinical impact of such a wide window has not been assessed.Methods We systematically searched PubMed/MEDLINE,Embase,Scopus,Web of Science,and Cochrane Library from database inception to 6 October 2021.Network meta-analysis was conducted on randomized controlled trials that assessed antibiotic treatment for AOM in children(PROSPERO CRD42020196107).Results For amoxicillin and amoxicillin-clavulanate,7-day regimens were noninferior to 10-day regimens in clinical responses[amoxicillin:risk ratio(RR)0.919(95%CI 0.820-1.031),amoxicillin-clavulanate:RR 1.108(0.957-1.282)],except for≤2 years.For the third-generation cephalosporins,7-day and 10-day regimens had similar clinical responses compared to placebo[7-day:RR 1.420(1.190-1.694),10-day:RR 1.238(1.125-1.362)compared to placebo].However,5-day regimens of amoxicillin-clavulanate and third-generation cephalosporins were inferior to 10-day regimens.Compared to amoxicillin,a shorter treatment duration was tolerable with amoxicillin-clavulanate.Conclusions Our findings indicated that 1O days of antibiotic use may be unnecessarily long,while the treatment duration should be longer than 5 days.Otherwise,5-day regimens would be sufficient for a modest treatment goal.Our findings revealed that the current wide range of recommended antibiotic durations may have influenced the clinical outcome of AOM,and a narrower antibiotic duration window should be re-established.

关键词： Amoxicillin-potassium Amoxicillin Antibacterial agents Cephalosporins Duration of therapy

A Study of the Impulse Wave Discharged from the Exits of Two Parallel Tubes

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Journal of Thermal Science 2003年第4期12卷 332-336,356页

作者： Yong-Hun kweon Heuy-dong Kim Toshiaki Setoguchi Toshiyuki Aoki School of Mechanical Engineering Andong National University Andong 760-749 KoreaSchool of Mechanical Engineering Andong National University Andong 760-749 KoreaDepartment of Mechanical Engineering Saga University Honjo Saga 840-8502 JapanDepartment of Energy Science and Engineering Kyushu University Kasuga Fukuoka 816-8580 Japan

The twin impulse wave leads to very complicated flow fields, such as Mach stem, spherical waves, and vortex ring. The twin impulse wave discharged from the exits of the two tubes placed in parallel is investigated to understand the detailed flow physics associated with the twin impulse wave, compared with those in a single impulse wave. In the current study, the merging phenomena and propagation characteristics of the impulse waves are investigated using a shock tube experiment and by numerical computations. The Harten-Yee''s total variation diminishing (TVD) scheme is used to solve the unsteady two-dimensional compressible Euler equations. The Mach number Ms of incident shock wave is changed below 1.5 and the distance between two-parallel tubes, L/d, is changed from 1.2 to 4.0. In the shock tube experiment, the twin impulse waves are visualized by a Schlieren optical system for the purpose of validation of computational work. The results obtained show that on the symmetric axis between two-parallel tubes, the peak pressure produced by the twin impulse waves and its location strongly depend upon the distance between two-parallel tubes, L/d and the incident shock Mach number, Ms. The predicted Schlieren images represent the measured twin-impulse wave with a good accuracy.

关键词：冲击波非稳态流振动波振动管可压缩性流球形波环形涡流

Nationwide Trends in the Prevalence of Cigarette and E-cigarette Smoking among Korean Adults between 2014-2021:A Representative Serial Study of 1.2 Million Individuals

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Biomedical and Environmental Sciences 2023年第10期36卷 996-998页

作者： Minji Kim Wonyoung Cho Jinseok Lee Yong Sung Choi Seung Geun Yeo Young Joo Lee Sang Youl Rhee Chanyang Min dong keon Yon Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea Department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Otolaryngology-Head&Neck Surgery Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Department of Obstetrics and Gynecology Kyung Hee University College of MedicineSeoulSouth Korea Department of Endocrinology and Metabolism Kyung Hee University College of MedicineSeoulKorea

Both cigarette and e-cigarette use cause respiratory tract damage and related health outcomes,and potentially increase the risk of coronavirus disease 2019(COVID-19)-related symptoms[1].Since the COVID-19 pandemic,loc... 详细信息

关键词： respiratory damage legal

基于2D多道地震和测井资料分析天然气水合物相关的地震烟囱分布及成因--以东海郁陵盆地为例

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海洋地质 2019年第1期35卷 1-16页

作者： Nyeon-keon Kang dong-geun Yoo Bo-yeon Yi 何玉林(译) 孟苗苗(校对) 不详广州海洋地质调查局水合物工程中心广州市510760

通过对多道地震反射特征和测井数据的分析,发现东海郁陵盆地有明显的地震烟囱,并根据其几何形状、地震反射模式、测井响应和岩心特征等分成两种类型。类型I表现为具有空白或杂乱地震反射模式的丘状特征。测井和岩心解释显示类型Ⅰ发育... 详细信息

通过对多道地震反射特征和测井数据的分析,发现东海郁陵盆地有明显的地震烟囱,并根据其几何形状、地震反射模式、测井响应和岩心特征等分成两种类型。类型I表现为具有空白或杂乱地震反射模式的丘状特征。测井和岩心解释显示类型Ⅰ发育有经均匀改造的泥岩和裂缝充填型天然气水合物。这种类型的地震烟囱主要分布在构造高部位以及几乎只在上新世沉积地层中出现。相反,类型Ⅱ表现为具有垂向叠置的挠曲地震反射模式的管状特征。基于测井数据和岩心,类型Ⅱ地震烟囱在并未突破原先沉积构造的基础上充填了裂隙充填型天然气水合物。这种类型沿着深部断裂分布,并主要发育于第四纪沉积地层中。本文初步认为,盆地局部的抬升导致海底第四纪沉积地层再改造作用是类型I地震烟囱发育的原因,而类型Ⅱ主要是第四纪时期流体通过深部断裂再度活化产生的裂缝垂向运移导致。

关键词：天然气水合物地震烟囱沉积物再改造水压裂缝郁陵盆地

Differences in Pandemic-Related Factors Associated with Alcohol and Substance Use among Korean Adolescents:Nationwide Representative Study

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Biomedical and Environmental Sciences 2023年第6期36卷 542-548页

作者： Hyunju Yon Sangil Park Jung U Shin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min Jinseok Lee Rosie Kwon Guillaume Fond Laurent Boyer Sunyoung Kim Namwoo Kim Sang Youl Rhee Jae Il Shin dong keon Yon Ho Geol Woo Department of Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Neurology Kyung Hee University Medical CenterSeoulRepublic of Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamRepublic of Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Department of Physical Medicine and Rehabilitation Lariboisière-Fernand Widal HospitalAP-HPUniversity Paris CitéParisFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulRepublic of Korea Department of Biomedical Engineering Kyung Hee UniversityYonginRepublic of Korea Assistance Publique-Hôpitaux de Marseille(AP-HM) Aix-Marseille UniversityCEReSSHealth Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Family Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Psychiatry Seoul St.Mary's HospitalThe Catholic University of KoreaCollege of MedicineSeoulRepublic of Korea Department of Endocrinology and Metabolism Kyung Hee University School of MedicineSeoulRepublic of Korea Department of Pediatrics Yonsei University College of MedicineSeoulRepublic of Korea Department of Pediatrics Kyung Hee University College of MedicineSeoulRepublic of Korea

The coronavirus disease 2019(COVID-19)pandemic has raised concerns about the mental health and social well-being of youth,including its potential to increase or exacerbate substance use behaviors[1].Among adolescents,the COVID-19pandemic has resulted in limited face-to-face school contact and thus missed milestones in preventing alcohol and substance use.

关键词： Alcohol raised alcohol

Ternary Forecast of Heavy Snowfall in the Honam Area, Korea

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Advances in Atmospheric Sciences 2009年第2期26卷 327-332页

作者： keon Tae SOHN Jeong Hyeong LEE Young Seuk CHO Department of Statistics Pusan National University Division of Management Information Science Dong-A University

The objective of this study is to improve the statistical modeling for the ternary forecast of heavy snowfall in the Honam area in Korea. The ternary forecast of heavy snowfall consists of one of three values, 0 for less than 50 mm, 1 for an advisory （50-150 ram）, and 2 for a warning （more than 150 mm）. For our study, the observed daily snow amounts and the numerical model outputs for 45 synoptic factors at 17 stations in the Honam area during 5 years （2001 to 2005） are used as observations and potential predictors respectively. For statistical modeling and validation, the data set is divided into training data and validation data by cluster analysis. A multi-grade logistic regression model and neural networks are separately applied to generate the probabilities of three categories based on the model output statistic （MOS） method. Two models are estimated by the training data and tested by the validation data. Based on the estimated probabilities, three thresholds are chosen to generate ternary forecasts. The results are summarized in 3 × 3 contingency tables and the results of the three-grade logistic regression model are compared to those of the neural networks model. According to the model training and model validation results, the estimated three-grade logistic regression model is recommended as a ternary forecast model for heavy snowfall in the Honam area.

关键词： ternary forecast of heavy snow MOS multi-grade logistic regression neural networks threshold