检索结果-南通市图书馆

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-Li Kang Yi Jiang hua-Wei Zhang Xiao-Mei Song Yu-Ze Li Wen-Li huang dong-dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SCTP performance improvement based on virtual receiver window

引用

The Journal of China Universities of Posts and Telecommunications 2013年第3期20卷 67-72页

作者： WANG Feng-hua xie dong-liang ZHANG Peng State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications

This article puts forward one algorithm for stream control transfer protocol （SCTP） improvement with limited receiver buffer （RBUF）. As is well known, SCTP is one of the most important transfer control protocol, but most researches focus on the situations without the RBUF limit. In this study, we analyze the impact of the RBUF size on the performance. Computer simulations show that the network utility is low in reliable transfer, when the RBUF size is smaller than bandwidth delay product. By studying the transmission sequence number （TSN） transfer progress, we find that the peer receiver window （PEER_RWND）, which lags behind the true receiver window （RWND）, leads to the poor network utility. To improve SCTP performance with limited RBUF, the virtual receiver window （VIRTUAL_RWND） is introduced. Based on the VIRTUAL_RWND, one algorithm is proposed to increase the sending rate. Computer simulations have evaluated an excellent performance of the proposed algorithm at both ideal link without lost packet and nonideal link with lost packet.

关键词： SCTP limited receiver buffer VIRTUAL_RWND

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Turbulent Agglomeration of Microparticles in a Cylinder Wake Flow Using LES-DEM:Focusing on the Effect of the Reynolds Number

引用

Journal of Thermal Science 2025年第1期 34-49页

作者： WANG Shuang MU Lin LI Xue xie Jun dong Ming School of Energy and Power Engineering Dalian University of Technology School of Optical Information and Energy Engineering Wuhan Institute of Technology School of Energy and Environment Shenyang Aerospace University

Turbulent agglomeration is viewed as a promising technology for enhancing fine particle removal *** better understand particle transport,agglomeration behaviors,and fluid-particle interactions,we numerically explored these phenomena under cylindrical vortex wake influence using a coupled large eddy simulation and discrete element method（LES-DEM） *** validity of the LES approach was verified by comparison with available direct numerical simulation（DNS） *** adopted the Johnson-Kendall-Roberts（JKR） contact model for particle-particle *** particle dispersion and agglomeration characteristics of particles with different diameters（dp=2-20 μm） in the laminar and transition of shear layer（TrSL） flow regimes were *** particles were concentrated at the vortex centers,while larger particles accumulated around the *** agglomeration efficiency exhibited an M-shaped profile spanwise（y-direction）.With increasing Reynolds number,the agglomeration efficiency and turbulence intensity *** particle agglomeration efficiency peaks at a certain Reynolds ***,at higher Reynolds numbers,reducing the residence time of particles in the flow field decreases the agglomeration efficiency.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

黄土中土壤层形成对河流水位、环境变化的响应

引用

山西师范大学学报（自然科学版） 2000年第2期14卷 63-66页

作者：李旭红马志正董艳卫华谢爱红山西师范大学地理系山西临汾041004

从黄河小浪底段河流阶地上古土壤形成过程和形态特征 ,分析证明 ,在距今 30万年以来 ,黄河曾经有两次丰水期 (高水位 ) .同时 ,由于环境的影响 ,其古土壤的形成是在丰水期及流水下切时期 ,因而 ,古土壤层的形成与河流水位、气候环境变... 详细信息

从黄河小浪底段河流阶地上古土壤形成过程和形态特征 ,分析证明 ,在距今 30万年以来 ,黄河曾经有两次丰水期 (高水位 ) .同时 ,由于环境的影响 ,其古土壤的形成是在丰水期及流水下切时期 ,因而 ,古土壤层的形成与河流水位、气候环境变化有一定的对应关系 .

关键词：小浪底古土壤河流水位环境变化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of process parameters on surface quality,composition segregation,microstructure and properties of QSn6.5-0.1 alloy slabs fabricated by HCCM horizontal continuous casting

引用

Journal of Iron and Steel Research International 2017年第3期24卷 273-281页

作者： Yang Liu Xin-hua Liu hua-dong Fu Min-xuan Lou Jian-xin xie Institute for Advanced Materials and Technology University of Science and Technology Beijing Beijing 100083 China

Columnar-grained QSn6. 5-0. 1 alloy slabs with a width of 70 mm and thickness of 10 mm were fabricated by heating-cooling combined mold（ HCCM） horizontal continuous casting. The effects of process parameters on solidification microstructure,surface quality,composition segregation and mechanical properties were studied. The results showed that the slabs with good surface quality,excellent mechanical properties and no obvious segregation could be prepared at the melt casting temperature of 1 250 ℃,the heating-mold temperature of 1 150- 1 200℃,the cooling water flow rate of 600 L / h and the casting speed of 20- 80 mm / min. The slabs had the yield strength of 124- 155 MPa,the elongation rate of 46. 6%- 56. 3% and the surface roughness of 0. 22- 0. 55μm,which enabled them to be directly processed without subsequent milling surface. The ratio of Sn content in the surface to that in the core was 0. 83- 1. 10,with an average value close to 1. 0,and not obviously influenced by process parameters. When the casting speed increased from 20 to 80 mm / min,the grain size changed little if the other process parameters were the same. When the heating-mold temperature increased from 1 150 to 1 200℃,the grain size was obviously refined and became more uniform if the casting speed was the same. Within the range of the casting speed at which the columnar grain structure could be obtained,the columnar grain size was mainly influenced by the heating-mold temperature.

关键词： QSn6.5 copper alloy Heating-cooling combined mold Horizontal continuous casting Microstructure Mechanical property Composition segregation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

影响后发障光切术后效果的临床观察

引用

山东医大基础医学院学报 2000年第5期14卷 289-290页

作者：刘力董卫红谢华袁明俊济南施尔明眼科医院 250001

目的 :分析后发障光切术后并发症及视力不增的原因及研究预防措施。方法 :对白内障现代囊外摘除及人工晶体植入术后 8d～ 5年后发障的 115例、148眼行Nd :YAG激光后囊膜光切术 ,术后次日复诊 ,随诊 7d～ 3个月。结果 :接受该法治疗的 11... 详细信息

目的 :分析后发障光切术后并发症及视力不增的原因及研究预防措施。方法 :对白内障现代囊外摘除及人工晶体植入术后 8d～ 5年后发障的 115例、148眼行Nd :YAG激光后囊膜光切术 ,术后次日复诊 ,随诊 7d～ 3个月。结果 :接受该法治疗的 115例 ,除 1例玻切术后硅油充满前房的患者膜切开不成功外 ,余者均切膜成功 ,成功率为 99.32 %。视力提高 10 8眼 ( 72 .97% ) ,不变 4 0眼 ( 2 7.0 3% )。视力由治疗前的 0 .31±0 .2 6提高到治疗后的 0 .56± 0 .37。结论 :后发障光切术是白内障术后因后发障而再次致盲患者有效的、非介入性的手术治疗 ,安全 ,患者无痛苦 ,成功率高 ,视力提高显著。白内障术后视力不提高系治疗前原有眼部病变所致 ,与激光治疗本身无相关性 ,并发症的发生则与激光能量及膜质量成正相关。因此 ,早期治疗和分次治疗可减少和预防并发症的发生。对Ⅲ级膜后发障的分次治疗尤为重要 ,可避免一次性过高使用能量 ,给周围组织带来不必要的损伤。

关键词：白内障外科手术激光手术后囊混浊治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tribological behaviors of spot-textured TiN coatings on M2 high-speed steel under boundary lubricated conditions

引用

Journal of University of Science and Technology Beijing 2007年第4期14卷 350-355页

作者： Guangneng dong Meng hua Jian Li Hing-Yin Ma Youbai xie Lubrication Theory and Bearing Institute Key Laboratory of the Education Ministry for Modern Design and Rotor-Bearing System Xi＇an Jioatong University Xi＇an 710049 China Department of Manufacturing Engineering and Engineering Management City University of Hong Kong 83 Tat Chee Avenue Kowloon Tong Kowloon Hong Kong China Wuhan Research Institute of Materials Protection Wuhan 430030 China

The effect of sliding duration on the tribological behaviors of spot patterned coatings was investigated. Two patterns based on physical vapor deposition （PVD） TiN coatings were used, such as, in-lined （IN） and staggered （ST） spots. The tribological behaviors were evaluated by using a Cameron-Plint wear test rig. The M2 steel discs deposited TiN coatings with IN and ST patterns slid against the ASSAB 17 tool steel pins at a speed of 0.23 m/s, in Shell Tellus T32 lubricant and were loaded with 900 N. The testing results on disc specimens with two types of PVD TiN spot patterns, all coated with a bias voltage of-180 V and slid for 4, 8 and 11 h respectively, were presented. The results revealed that the in-lined coatings possessed relatively better wear behaviors than the staggered pattern coatings. Mechanisms for such superiority and for the cause of peeling were discussed. A relevant design approach was suggested for the application of such patterned coatings.

关键词： vapor deposited coating texture friction wear boundary lubrication

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Emergent Z2 topological invariant and robust helical edge states in two-dimensional topological metals

引用

Science China(Physics,Mechanics & Astronomy) 2020年第10期63卷 105-110页

作者： Chui-Zhen Chen hua Jiang dong-Hui Xu X.C.xie Institute for Advanced Study and School of Physical Science and Technology Soochow UniversitySuzhou 215006China Department of Physics Hubei UniversityWuhan 430062China International Center for Quantum Materials School of PhysicsPeking UniversityBeijing 100871China CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of SciencesBeijing 100190China Beijing Academy of Quantum Information Sciences Beijing 100193China

In this work,we study the effects of disorder on topological metals that support a pair of helical edge modes deeply embedded inside the gapless bulk ***,we predict that a quantum spin Hall(QSH)phase can be obtained from such topological metals without opening a global band *** be specific,disorder can lead to a pair of robust helical edge states which is protected by an emergent Z2 topological invariant,giving rise to a quantized conductance plateau in transport *** results are instructive for solving puzzles in various transport experiments on QSH materials that are intrinsically *** work also will inspire experimental realization of the QSH effect in disordered topological metals.

关键词： topological metal disorder Z2 topological invariant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analytical model and simulation of the Schottky effect on a cryocooled bialkali photocathode

引用

Nuclear Science and Techniques 2018年第5期29卷 82-86页

作者： hua-Mu xie Er-dong Wang Ke-Xin Liu State Key Laboratory of Nuclear Physics and Technology Institute of Heavy Ion PhysicsPeking UniversityBeijing 100871China Brookhaven National Laboratory UptonNY 11973USA

A bialkali photocathode with the quantum efficiency(QE) in the range of a few percent was fabricated for the 704 MHz SRF gun at Brookhaven National Laboratory. The photoemission properties of the bialkali photocathode in the superconducting radio frequency(SRF)gun were measured for the first time, and a good beam experiment result was obtained. The performance of the bialkali photocathode was investigated during the commissioning process of the 704 MHz SRF gun. The effect of electric field on the QE of the cryo-cooled cathode was characterized by an analytical model and a code for the first time.

关键词： Schottky effect Bialkali photocathode Surface potential Superconducting radio frequency gun

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Two Faces of One Seed： Hormonal Regulation of Dormancy and Germination

引用

Molecular Plant 2016年第1期9卷 34-45页

作者： Kai Shu Xiao-dong Liu Qi xie Zu-hua He State Key Laboratory of Plant Genomics Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China National Key Laboratory of Plant Molecular Genetics Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai 200032 China Key Laboratory of Crop Ecophysiology and Farming System in Southwest China Institute of Ecological Agriculture Sichuan Agricultural UniversityChengdu 611130 China College of Agronomy Xinjiang Agricultural University Urumqi 830052 Xinjiang China These authors contributed equally to this article

Seed plants have evolved to maintain the dormancy of freshly matured seeds until the appropriate time for germination. Seed dormancy and germination are distinct physiological processes, and the transition from dormancy to germination is not only a critical developmental step in the life cycle of plants but is also impor- tant for agricultural production. These processes are precisely regulated by diverse endogenous hormones and environmental cues. Although ABA （abscisic acid） and GAs （gibberellins） are known to be the primary phytohormones that antagonistically regulate seed dormancy, recent findings demonstrate that another phytohormone, auxin, is also critical for inducing and maintaining seed dormancy, and therefore might act as a key protector of seed dormancy. In this review, we summarize our current understanding of the sophisticated molecular networks involving the critical roles of phytohormones in regulating seed dormancy and germination, in which AP2-domain-containing transcription factors play key roles. We also discuss the interactions （crosstalk） of diverse hormonal signals in seed dormancy and germination, focusing on the ABA/GA balance that constitutes the central node.

关键词： seed dormancy germination ABA GA auxin crosstalk

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：