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Macrostructure and properties of thin walled copper tubes prepared by the downward continuous unidirectional solidification method

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International Journal of Minerals,Metallurgy and Materials 2010年第1期17卷 63-68页

作者： Xi shen Hong Zhang Zi-dong Wang hua-fen Lou Yi-ming Jia Ping-xia Hu School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China CHINALCO Luoyang Copper Co. Ltd. Luoyang 471000 China

The macrostructure and properties of the thin walled copper tube prepared by the downward continuous unidirectional solidification （DCUS） method were studied. The result shows that the macrostructure is closely related to the solid-liquid interface profile, which is influenced by the distance between the cooling water location and the solidification front. The mechanical properties of the thin walled copper tube prepared by the DCUS method are near those of the normal cast copper, and it has good relative density, electrical conductivity, and elongation, which are not greatly affected by casting speed. The thin walled copper tube prepared by the DCUS method also has good processing properties that can be taken to further drawing procedures directly without an intermediate process, and obtains good mechanical properties with the total processing rate of 89.8%.

关键词： unidirectional solidification copper tube short process macrostructure mechanical properties

Effects of Temperature and Hydraulic Residence Time (HRT) on Treatment of Dilute Wastewater in a Carrier Anaerobic Baffled Reactor

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Biomedical and Environmental Sciences 2008年第6期21卷 460-466页

作者： hua-JUN FENG LI-FANG HU DAN SHAN CHENG-RAN FANG dong-shenG shen College of Environmental and Resource Sciences Zhejiang University Hangzhou 310029 Zhejiang China Environmental Protection Bureau of Yuhang District of Hangzhou Hangzhou 311100 Zhejiang China

Objective To examine the effect of hydraulic residence time （HRT） on the performance and stability, to treat dilute wastewater at different operational temperatures in a carrier anaerobic baffled reactor （CABR）, and hence to gain a deeper insight into microbial responses to hydraulic shocks on the base of the relationships among macroscopic performance, catabolic intermediate, and microcosmic alternation. Methods COD, VFAs, and microbial activity were detected with constant feed strength （300 mg/L） at different HRTs （9-18 h） and temperatures （10℃-28℃） in a CABR. Results The removal efficiencies declined with the decreases of HRTs and temperatures. However, the COD removal load was still higher at short HRT than at long HRT. Devastating reactor performance happened at temperature of 10℃ and at HRT of 9 h. HRTs had effect on the VFAs in the reactor slightly both at high and low temperatures, but the reasons differed from each other. Microbial activity was sensitive to indicate changes of environmental and operational parameters in the reactor. Conclusion The CABR offers to certain extent an application to treat dilute wastewater under a hydraulic-shock at temperatures from 10℃to 28℃.

关键词： Carrier anaerobic baffled reactor Dilute wastewater Hydraulic residence time Temperature

PLA_(2) mediates the innate immune response in Asian corn borer, Ostrinia furnacalis

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Insect Science 2022年第1期29卷 245-258页

作者： Jia-Yue Ji Zhao-hua Yin Sha-Sha Zhang dong-Xu shen Chun-Ju An Department of Entomology College of Plant ProtectionChina Agricultural UniversityBeijing100193China Jiangsu Key Laboratory of Sericutural Biology and Biotechnology School of BiotechnologyJiangsu University of Science and TechnologyZhenjiangJiangsu212018China Key Laboratory of Silkworm and Mulberry Genetic Improvement Ministry of Agriculture and Rural AffairsSericultural Research InstituteChinese Academy of Agricultural SciencesZhenjiangJiangsu212018China

The eicosanoid signaling pathway mediates insect immune reactions to a wide range of stimuli. This pathway begins with the biosynthesis of arachidonic acid (AA) from the hydrolysis of phospholipids catalyzed by phospholipase A_(2) (PLA_(2)). We report here that the PLA_(2) inhibitor, dexamethasone (DEX), impaired the innate immune response including nodulation, encapsulation, and melanization in Ostrinia furnacalis larvae, while AA partially reversed these effects of DEX. We cloned a full-length complementary DNA encoding a PLA_(2), designated as OfsPLA_(2), from O. furnacalis. The open reading frame of OfsPLA_(2) encodes a 195-amino acid residue protein with a 22-residue signal peptide. Sequence alignment analyses indicated that O. furnacalis PLA_(2) might be a Group III secretory PLA_(2). The highest transcript levels of OfsPLA_(2) were detected in the fat body, and its transcript levels increased dramatically after infection with Escherichia coli, Micrococcus luteus, or Beauveria bassiana. Recombinant OfsPLA_(2) significantly induced prophenoloxidase (PPO) activation in larval hemolymph in the presence of Ca^(2+) and encapsulation of agarose beads. Injection of recombinant OfsPLA_(2) into larvae resulted in increased transcript levels of attacin, defencin, and moricin-3 genes. Our results demonstrate the involvement of the eicosanoid signaling pathway in the innate immune response of O. furnacalis larvae and provide new information about the roles of O. furnacalis secretory PLA_(2) in activating PPO and antimicrobial peptide production.

关键词： eicosanoid signal pathway innate immune response Ostrinia furnacalis phospholipase A_(2)(PLA_(2))

SET8 Inhibition Potentiates Radiotherapy by Suppressing DNA Damage Repair in Carcinomas

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Biomedical and Environmental Sciences 2022年第3期35卷 194-205页

作者： PAN dong DU Ya Rong LI Rong shen Ai hua LIU Xiao dong LI Chuan Yuan HU Bu Rong Department of Radiological Health and Radiation Medicine School of Public Health and ManagementWenzhou Medical UniversityWenzhou 325035ZhejiangChina Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences&Key laboratory of Space Radiobiology of Gansu province Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000GansuChina Department of Dermatology Duke University Medical CenterDurhamNC27710USA

Objective SET8 is a member of the SET domain-containing family and the only known lysine methyltransferase(KMT)that monomethylates lysine 20 of histone H4(H4 K20 me1).SET8 has been implicated in many essential cellular processes,including cell cycle regulation,DNA replication,DNA damage response,and *** is no conclusive evidence,however,regarding the effect of SET8 on *** the current study we determined the efficacy of SET8 inhibition on radiotherapy of tumors and the underlying *** First,we explored the radiotherapy benefit of the SET8 expression signature by analyzing clinical ***,we measured a series of biological endpoints,including the xenograft tumor growth in mice and apoptosis,frequency of micronuclei,and foci of 53 BP1 andγ-H2 AX in cells to detect the SET8 effects on *** sequencing and subsequent experiments were exploited to verify the mechanism underlying the SET8 effects on *** Low expression of SET8 predicted a better benefit to radiotherapy in lung adenocarcinoma(LUAD)and invasive breast carcinoma(BRCA)***,genetic deletion of SET8 significantly enhanced radiation treatment efficacy in a murine tumor model,and A549 and MCF7 cells;SET8 overexpression decreased the ***8 inhibition induced more apoptosis,the frequency of micronuclei,and blocked the kinetics process of DNA damage repair as 53 BP1 andγ-H2 AX foci remained in ***,RNF8 was positively correlated with the SET8 impact on DNA damage *** Our results demonstrated that SET8 inhibition enhanced radiosensitivity by suppressing DNA damage repair,thus suggesting that SET8 potentiated radiotherapy of *** new inhibitors of SET8 are synthesized and tested in preclinical and clinical settings,combining SET8 inhibitors with radiation warrants consideration for precise radiotherapy.

关键词： SET8 Histone methylation DNA repair Radiotherapy Carcinoma

Co,K-Supported Hexagonal Mesoporous Silicas for Catalytic Oxidation of 4-t-Butyltoluene

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Chemical Research in Chinese Universities 2010年第4期26卷 622-625页

作者： YU Wei-hua ZHOU Chun-hui TONG dong-shen FANG Mei ZHANG Bo Research Group for Advanced Materials ＆ Sustainable Catalysis（AMSC） College of Chemical Engineering and Materials Science Zhejiang University of Technology Hangzhou 310014 P R. China

Co,K-Supported hexagonal mesoporous silicas（HMS） have been prepared by incipient wetness impregnation with cobalt acetate tetrahydrate and potassium acetate as metal precursors, and ethylene glycol as impregnation solvent. The products have been characterized via powder X-ray diffraction, N2 adsorption-desorption isotherms and diffuse reflectance UV-Vis spectroscopy. The divalent cobalt with a tetrahedral oxygen coordination exists mainly in the calcined samples. The catalytic properties have been tested for the oxidation of 4-t-butyltoluene with dioxygen in liquid phase at mild conditions. The products offered good catalytic activities in the oxidation reactions. Co-K-HMS catalyst with loading 4% Co and 2% K（mass fraction） affords a higher yield（22.4%） of 4-t-butylbenzaldehyde at a conversion of 28.3% under the reaction conditions. Adding a proper amount of potassium in Co-HMS results in an improvement catalytic activity and stability.

关键词： Mesoporous silica Catalyst Cobalt Potassium Oxidation

The Geographic Information Grid System Based on Mobile Agent

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Wuhan University Journal of Natural Sciences 2006年第1期11卷 304-308页

作者： shen Zhi-dong TONG Qiang huaNG Xian-feng WANG hua-min School of Computer Wuhan University Wuhan 430072 Hubei China Software College Northeastern University Shenyang 110004 Liaoning China State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing Wuhan University Wuhan 430072 Hubei China Research Center of Spatial Information and Digital Engineering Wuhan University Wuhan 430072 Hubei China

We analyze the deficiencies of current application systems, and discuss the key requirements of distributed Geographie Information serviee （GIS）, We construct the distributed GIS on grid platform. Considering the flexibility and efficiency, we integrate the mobile agent technology into the system. We propose a new prototype system, the Geographic Information Grid System （GIGS） based on mobile agent. This system has flexible services and high performance, and improves the sharing of distributed resources. The service strategy of the system and the examples are also presented.

关键词： grid geographic information system (GIS) spatial data mobile agent

Stability of second-order stochastic neutral partial functional differential equations driven by impulsive noises

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Science China(Information Sciences) 2016年第11期59卷 117-127页

作者： Feng JIANG hua YANG Yi shen School of Statistics and Mathematics Zhongnan University of Economics and Law School of Automation Huazhong University of Science and Technology School of Mathematics and Computer Science Wuhan Polytechnic University

This paper investigates the stability of second-order stochastic neutral partial functional differential equations driven by impulsive noises. Some sufficient conditions ensuring pth moment exponential stability of the second-order stochastic neutral partial functional differential equations driven by impulsive noises are obtained by establishing a new impulsive-integral inequality. These existing results are generalized and improved by the present study. Finally, an example is given to show the effectiveness of our results.

关键词： second-order stochastic neutral partial functional differential equations exponential stability impulsive noises sine family cosine family

An algorithm for identifying symmetric variables based on the order eigenvalue matrix

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Frontiers of Information Technology & Electronic Engineering 2017年第10期18卷 1644-1653页

作者： Xiao-hua LI Ji-zhong shen Campus Information Center Zhejiang University Hangzhou 310027 China College of lnformation Science & Electronic Engineering Zhejiang University Hangzhou 310027 China

To simplify the process for identifying 12 types of symmetric variables in Boolean functions, we propose a new symmetry detection algorithm based on minterm expansion or the truth table. First, the order eigenvalue matrix based on a truth table is defined according to the symmetry definition of a logic variable. By analyzing the constraint conditions of the order eigenvalue matrix for 12 types of symmetric variables, an algorithm is proposed for identifying symmetric variables of the Boolean function. This algorithm can be applied to identify the symmetric variables of Boolean functions with or without don't-care terms. The proposed method avoids the restriction by the number of logic variables of the graphical method, spectral coefficient methods, and AND-XOR expansion coefficient methods, and solves the problem of completeness in the fast computation method. The algorithm has been implemented in C language and tested on MCNC91 benchmarks. The application results show that, compared with the traditional methods, the new algorithm is an optimal detection method in terms of the applicability of the number of logic variables, the Boolean function including don't-care terms, detection type, and complexity of the identification process.

关键词： Boolean function Symmetric variable Boolean logic algebra system Order eigenvalue matrix Truth table

Hydrodynamic Characteristics of Undular Tidal Bores in the Qiantang River Based on Field Observations

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China Ocean Engineering 2024年第3期38卷 505-518页

作者： ZHANG Shu-yu PAN Cun-hong ZHANG shen-yang LI Ruo-hua CHENG Wenlong XIE dong-feng Zhejiang Tongji Vocational College of Science and Technology Hangzhou 311231China Zhejiang Institute of Hydraulics and Estuary Hangzhou 310020China

Understanding the undular tidal bores in the Qiantang River is essential for effective river management and *** breaking tidal bores have been studied extensively, reports on undular tidal bores in the Qiantang Riverremain limited. Furthermore, observed data on undular tidal bores fulfilling the requirements of short measurementtime intervals, and spring, medium, and neap tide coverage, and providing detailed data for the global vertical stratificationof flow velocity are quite limited. Based on field observations at Qige in the Qiantang estuary, we analyzedthe characteristics of undular tidal bores. The results showed that the flooding amplitude (a) of the first wave isalways larger than its ebbing amplitude (b). Moreover, the vertical distribution of the maximum flood velocity exhibitesthree shapes, influenced by the tidal range, while that of the maximum ebb velocity exhibites a single shape. Duringthe initial phase of the flood tide in the spring and medium tides, the upper water body experiences multiple oscillatingchanges along the flow direction, corresponding to the alternating process of the crest and trough of the tide levelupon the arrival of the tidal bore. The tidal range is a crucial parameter in tidal bore hydrodynamics. By establishingthe relationship between hydrodynamic parameters and tidal range, other hydrodynamic parameters, such as the tidalbore height, maximum flood depth–averaged velocity, maximum flood stratified velocity at the measurement points,and duration of the flood tide current, can be effectively predicted, thereby providing an important reference for rivermanagement and maintenance.

关键词： tidal bores Qiantang Estuary tidal bore height tidal bore velocity propagation speed