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Parametric analysis of craniocerebral injury mechanism in pedestrian trafficaccidents based on finite element methods

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Chinese Journal of Traumatology 2024年第4期27卷 187-199页

作者： Jin-Ming Wang Zheng-dong Li Chang-Sheng Cai Ying Fan Xin-Biao Liao Fu Zhang Jian-Hua Zhang dong-Hua zou Academy of Forensic Science Shanghai Key Laboratory of Forensic MedicineKey Laboratory of Forensic ScienceMinistry of JusticeShanghai Forensic Service PlatformShanghai200063China School of Forensic Medicine Guizhou Medical UniversityGuiyang550004China Key Laboratory of Forensic Pathology Ministry of Public Security PR ChinaGuangzhou510050China

Purpose:The toughest challenge in pedestrian traffic accident identification lies in ascertaining *** study aimed to systematically simulate and parameterize 3 types of craniocerebral injuryincluding impact injury,fall injury,and run-over injury,to compare the injury response outcomes ofdifferent injury ***:Based on the total human model for safety(THUMS)and its enhanced human model THUMShollow structures,a total of 84 simulations with 3 injury manners,different loading directions,andloading velocities were *** Mises stress,intracranial pressure,maximum principal strain,cumulative strain damage measure,shear stress,and cranial strain were employed to analyze the injuryresponse of all areas of the *** examine the association between injury conditions and injuryconsequences,correlation analysis,principal component analysis,linear regression,and stepwise linearregression were ***:There is a significant correlation observed between each criterion of skull and brain injury(p40 km/h),the Von Mises stress on the skull waswith a high possibility exceed the threshold for skull fracture(100 MPa).When falling and makingtemporal and occipital contact with the ground,the opposite side of the impacted area experienceshigher frequency stress concentration than contact at other ***-over injuries tend to have amore comprehensive craniocerebral injury,with greater overall deformation due to more adequate kinetic energy *** mean value of maximum principal strain of brain and Von Mises stress ofcranium at run-over condition are 1.39 and 403.8 MPa,while they were 1.31,94.11 MPa and 0.64,120.5 MPa for the impact and fall conditions,*** impact velocity also plays a significant rolein craniocerebral injury in impact and fall loading conditions(the p

关键词： Craniocerebral injury Finite element Injury mechanism Traffic accident Biomechanism Forensic practice

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TCERG1L hypermethylation is a risk factor of diabetic retinopathy in Chinese children with type 1 diabetes

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 537-544页

作者： Yu Qian Ying Xiao Qiu-Rong Lin Zhao-Yu Xiang Li-Pu Cui Jia-Qi Sun Si-Cong Li Xin-Ran Qin Hai-dong zou Chen-Hao Yang Pei-Yao Jin Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai First People’s HospitalShanghai 200080China Shanghai Eye Diseases Prevention&Treatment Center Shanghai Eye HospitalShanghai 200040China National Clinical Research Center for Eye Diseases Shanghai Clinical Research Center for Eye DiseasesShanghai Key Clinical SpecialtyShanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghai 200080China Department of Ophthalmology Children’s Hospital of Fudan UniversityShanghai 201102China

●AIM:To identify the differential methylation sites(DMS)and their according genes associated with diabetic retinopathy(DR)development in type 1 diabetes(T1DM)children.●METHODS:This study consists of two surveys.A total of 40 T1DM children was included in the first *** no participant has DR,retina thinning was used as a surrogate indicator for *** lowest 25%participants with the thinnest macular retinal thickness were included into the case group,and the others were *** DNA methylation status was assessed by the Illumina methylation 850K array BeadChip assay,and compared between the case and control *** DMS with a potential role in diabetes were *** second survey included 27 T1DM children,among which four had *** methylation patterns of the four DMS identified by 850K were compared between participants with and without DR by pyrosequencing.●RESULTS:In the first survey,the 850K array revealed 751 sites significantly and differentially methylated in the case group comparing with the controls(|Δβ|>0.1 and Adj.P0.05)between participants with and without DR.●CONCLUSION:The hypermethylation of the TCERG1L gene is a risk factor for DR development in Chinese children with T1DM.

关键词： DNA methylation 850K array pyrosequencing diabetic retinopathy type 1 diabetes children

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Plant genomic resources at National Genomics Data Center:assisting in data-driven breeding applications

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aBIOTECH 2024年第1期5卷 94-106页

作者： dongmei Tian Tianyi Xu Hailong Kang Hong Luo Yanqing Wang Meili Chen Rujiao Li Lina Ma Zhonghuang Wang Lili Hao Bixia Tang dong zou Jingfa Xiao Wenming Zhao Yiming Bao Zhang Zhang Shuhui Song National Genomics Data Center Beijing Institute of GenomicsChinese Academy of Sciences&China National Center for BioinformationBeijing 100101China CAS Key Laboratory of Genome Sciences and Information Beijing Institute of GenomicsChinese Academy of Sciences&China National Center for BioinformationBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Genomic data serve as an invaluable resource for unraveling the intricacies of the higher plant systems,including the constituent elements within and among *** various efforts in genomic data archiving,integrative analysis and value-added curation,the National Genomics Data Center(NGDC),which is a part of the China National Center for Bioinformation(CNCB),has successfully established and currently maintains a vast amount of database *** dedicated initiative of the NGDC facilitates a data-rich ecosystem that greatly strengthens and supports genomic research ***,we present a comprehensive overview of central repositories dedicated to archiving,presenting,and sharing plant omics data,introduce knowledgebases focused on variants or gene-based functional insights,highlight species-specific multiple omics database resources,and briefly review the online application *** intend that this review can be used as a guide map for plant researchers wishing to select effective data resources from the NGDC for their specific areas of study.

关键词： Plant-omics data Data repositories Data integration Knowledgebase Plant genomics

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推进轴系弯-纵耦合非线性效应对推力测量精度影响研究

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船舶力学 2024年第7期28卷 1063-1072页

作者：邹冬林马相龙吴昊薛林杨宇泽塔娜饶柱石上海交通大学振动、冲击、噪声研究所机械系统与振动国家重点实验室上海200240 上海船舶设备研究所上海200031 高新船舶与深海开发装备协同创新中心上海200240

高精度监测推进轴系推力对船舶快速性预报、船-机-桨优化匹配及轴系健康管理等具有重要意义。然而,对于超长推进轴系,由于其跨距大、细长比(轴系半径与长度之比)小、且承受推力大,此时轴系将产生严重弯-纵耦合非线性变形。这将对基于应... 详细信息

高精度监测推进轴系推力对船舶快速性预报、船-机-桨优化匹配及轴系健康管理等具有重要意义。然而,对于超长推进轴系,由于其跨距大、细长比(轴系半径与长度之比)小、且承受推力大,此时轴系将产生严重弯-纵耦合非线性变形。这将对基于应变或变形位移等形变信息来测量推力的方法产生重要影响。因此,本文研究推进轴系弯-纵耦合非线性效应对推力测量精度的影响。考虑Von Karman非线性位移-应变关系,利用Hamilton变分原理结合有限元方法建立推进轴系非线性力学模型,研究弯-纵耦合效应对轴系变形位移和应变的影响规律,以及由此引起的推力测量误差。研究结果表明:在低转速时,轴系弯-纵耦合效应较弱,对推力测量影响很小;高转速时,忽略轴系弯-纵耦合效应将引起较大测量误差(240 r/min时,误差可达13.95%);测点越靠近螺旋桨,弯-纵耦合效应越强,推力测量误差越大,因此将测点布置在轴系前端推力轴承附近可有效减少轴系弯-纵耦合效应引起的测量误差。研究结果对跨度大、细长比小的超长轴系推力测量有指导意义。

关键词：推进轴系推力测量非线性弯-纵耦合有限元法

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环境化工原理课程思政教学探索与实践

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化工高等教育 2024年第1期41卷 67-71,123页

作者：邹栋仲兆祥南京工业大学环境科学与工程学院江苏南京211816

在专业课程教学中深入挖掘并有机融入思政元素,已经成为新工科背景下课程改革的要求与趋势。环境化工原理作为环境类专业的一门必修基础课程,其教学中存在教师对课程思政重要性认识不足、与时俱进观念不强、未落实到实践等诸多问题。对... 详细信息

在专业课程教学中深入挖掘并有机融入思政元素,已经成为新工科背景下课程改革的要求与趋势。环境化工原理作为环境类专业的一门必修基础课程,其教学中存在教师对课程思政重要性认识不足、与时俱进观念不强、未落实到实践等诸多问题。对此,文章在论述课程教学与思政教育有机融合的必要性和契合性的基础上,从教学方式和技术、师资队伍建设、师生评价体系、教学实践形式四个方面提出解决策略,以期为该课程的思政教学改革提供参考。

关键词：环境化工原理课程思政教学改革

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前沿科研成果融入环境化工原理实验教学——纳米纤维膜的制备与膜分离

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广东化工 2024年第6期51卷 144-146,84页

作者：邹栋仲兆祥南京工业大学江苏南京211816

设计了一个在纳米纤维膜中合成MnOx晶体粒子,协同去除颗粒物和甲醛的环境化工原理实验。首先,在静电纺丝液中加入醋酸锰前驱体,采用静电纺丝技术制备出纳米纤维膜。然后,将纳米纤维膜在高温下热解。热解之后,醋酸锰原位分解为MnOx晶体... 详细信息

设计了一个在纳米纤维膜中合成MnOx晶体粒子,协同去除颗粒物和甲醛的环境化工原理实验。首先,在静电纺丝液中加入醋酸锰前驱体,采用静电纺丝技术制备出纳米纤维膜。然后,将纳米纤维膜在高温下热解。热解之后,醋酸锰原位分解为MnOx晶体。本实验可以锻炼提高学生的实验动手能力,帮助学生熟悉实验仪器。同时,可以使学生更好地了解膜分离和静电纺丝技术相关知识。

关键词：静电纺丝纳米纤维热解细颗粒物甲醛

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Effects of Photodynamic Therapy on Nav1.7 Expression in Spinal Dorsal Root Ganglion Neurons

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Current Medical Science 2022年第6期42卷 1267-1272页

作者： dong-xu zou Xiao-zhen LI Hong CAI Medical School of Chinese PLA Beijing100853China Department of Dermatology Air Force Medical CenterPLABeijing100142China

Objective The aim of this study was to examine the effects of photodynamic therapy(PDT)on the expression of Nav1.7 in spinal dorsal root ganglion(DRG)*** The primary DRG neurons from newborn SD rats were *** cells were identified by neuron-specific enolase immunofluorescence *** neurons were divided into four groups:control group,photosensitizer group,laser group,and PDT *** cell viability was detected by a cell counting kit-8(CCK8)***-PCR and Western blotting were used to determine the mRNA and protein expression levels of Nav1.7 in DRG *** The purity of the cultured primary DRG neurons was greater than 90%.Compared with the control group,no significant change was found in the cell viability of the photosensitizer group,while the viability in the laser group and the PDT group was significantly *** mRNA and protein expression levels of Nav1.7 were significantly greater in the laser group and the PDT group than in the control *** the same time,the mRNA and protein expression levels of Nav1.7 were greater in the laser group than in the PDT *** Both laser and PDT could upregulate the expression of Nav1.7 in DRG neurons,and the promoting effect might be related to the pain induced by clinical *** study provides a research basis for the use of laser and PDT to treat pain.A better understanding of the relationship between Nav1.7 and PDT can help clinicians better manage PDT-related pain.

关键词： photodynamic therapy pain dorsal root ganglion Nav1.7 laser

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“环境与可持续发展”课程思政探索与教学实践

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教育教学论坛 2024年第27期 93-96页

作者：康玉堂邹栋仲兆祥南京工业大学环境科学与工程学院江苏南京211816

“环境与可持续发展”是当代大学生素质教育的必修课程之一,其授课内容中蕴含着十分丰富的思政元素,是大学生思想政治教育的优良土壤。然而,在实际授课过程中,该课程存在思政元素的挖掘不够深入、思政教育的实施方案比较混乱等诸多问题... 详细信息

“环境与可持续发展”是当代大学生素质教育的必修课程之一,其授课内容中蕴含着十分丰富的思政元素,是大学生思想政治教育的优良土壤。然而,在实际授课过程中,该课程存在思政元素的挖掘不够深入、思政教育的实施方案比较混乱等诸多问题。为此,深度挖掘了“环境与可持续发展”课程中的思政元素,还系统梳理了课程思政的融入方式和教学方法,并结合《水污染控制工程》这一典型授课章节对本课程的思政元素融入和教学进行了案例分析。

关键词：教学改革课程思政环境保护可持续发展

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5G RedCap技术浅析及性能验证

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电信工程技术与标准化 2024年第3期37卷 7-12,30页

作者：黄雯君邹东伯张晨曦中国移动通信集团设计院有限公司北京100080 中国移动通信集团湖北有限公司武汉430000

5G NR技术具有超大带宽、超低时延高可靠性和海量链接三大技术特点,然而高成本和高功耗使其在物联网领域的应用受到限制。作为5G NR的轻量化技术,5G RedCap通过裁剪终端能力,大幅降低了5G物联网终端成本,同时又继承了5G NR网络的优越特... 详细信息

5G NR技术具有超大带宽、超低时延高可靠性和海量链接三大技术特点,然而高成本和高功耗使其在物联网领域的应用受到限制。作为5G NR的轻量化技术,5G RedCap通过裁剪终端能力,大幅降低了5G物联网终端成本,同时又继承了5G NR网络的优越特性。相比5G NR和4G网络,5G RedCap网络具备独特的技术优势。本文首先介绍了5G RedCap使用的关键技术,并结合技术特点,分析了5G RedCap的性能指标;之后对5G NR站点进行软件升级和5G RedCap特性开启,对5G RedCap的性能和功能进行了双重验证;最后对5G RedCap技术未来面临的挑战进行了分析。

关键词： 5G RedCap 5G NR 终端复杂度

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Brain Cognition Mechanism-Inspired Hierarchical Navigation Method for Mobile Robots

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Journal of Bionic Engineering 2024年第2期21卷 852-865页

作者： Qiang zou Chengdong Wu Ming Cong dong Liu Faculty of Robot Science and Engineering Northeastern UniversityShenyang110819China School of Mechanical Engineering Dalian University of TechnologyDalian116024China

Autonomous navigation is a fundamental problem in *** methods generally build point cloud map or dense feature map in perceptual space;due to lack of cognition and memory formation mechanism,traditional methods exist poor robustness and low cognitive *** a new navigation technology that draws inspiration from mammal’s navigation,bionic navigation method can map perceptual information into cognitive space,and have strong autonomy and environment *** improve the robot’s autonomous navigation ability,this paper proposes a cognitive map-based hierarchical navigation ***,the mammals’navigation-related grid cells and head direction cells are modeled to provide the robots with location *** then a global path planning strategy based on cognitive map is proposed,which can anticipate one preferred global path to the target with high efficiency and short ***,a hierarchical motion controlling method is proposed,with which the target navigation can be divided into several sub-target navigation,and the mobile robot can reach to these sub-targets with high confidence ***,some experiments are implemented,the results show that the proposed path planning method can avoid passing through obstacles and obtain one preferred global path to the target with high efficiency,and the time cost does not increase extremely with the increase of experience nodes *** motion controlling results show that the mobile robot can arrive at the target successfully only depending on its self-motion information,which is an effective attempt and reflects strong bionic properties.

关键词： Bionic navigation Spatial localization cells Global path planning Hierarchical motion controlling

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