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Fast Li-ion conduction enabled by graphite fluoride flakes in solid polymer electrolyte

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Rare Metals 2023年第10期42卷 3337-3344页

作者： qing-Hui Li Xiao-Fen Wang Shi-Yuan Zhu qing-dong Zhong Song-Li Liu Qiong-Yu Zhou School of Electrical and Information Engineering Changsha University of Science and TechnologyChangsha410114China School of Materials Science and Hydrogen Energy Foshan UniversityFoshan528000China School of Materials Science and Engineering Shanghai UniversityShanghai200444China School of Materials Science and Engineering Yangtze Normal UniversityChongqing400715China

The Li-metal anode in rechargeable Li-metal batteries with a high energy density suffers the side reaction with the liquid electrolytes,resulting in the associated capacity degradation and safety *** electrolytes are designed to solve the safety problems caused by dendrite growth and the limited electrochemical stability of liquid ***,a poly(ethylene oxide)(PEO)-lithium bis(trifluoromethanesulfonyl) imide(LiTFSI) solid polymer electrolyte(SPE) with cost-wise.

关键词： electrolyte conduction polymer

Does nature-based solution sustain grassland quality? Evidence from rotational grazing practice in China

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Journal of Integrative Agriculture 2023年第8期22卷 2567-2576页

作者： LI dong-qing ZHANG Ming-xue Lü Xin-xin HOU Ling-ling Institute of Agricultural Economics and Development Chinese Academy of Agricultural SciencesBejing 100081P.R.China China Center for Agricultural Policy School of Advanced Agricultural SciencesPeking UniversityBeijing 100871P.R.China

Rotational grazing is considered as one of the nature-based solutions(NbS)to grassland protection by natural ***,its effects on improving grassland quality are still unclear when it is adopted by *** a householdlevel panel data from field survey in two main pastoral provinces of China,empirical results from fixed-effect model and instrumental approach show that rotational grazing practices have insignificant short-term effects on grassland quality,but have positive long-term *** addition,rotational grazing practices can improve grassland quality when villages invest public infrastructure or herders have private supporting measures for more efficiency livestock *** analysis shows that herders adopting rotational grazing have higher grazing intensity,higher supplementary intensity and more livestock-house-feeding days,which indicate herders can utilize more efficient livestock management without increasing pressure on natural *** also find that herders with pastoral income are more likely to adopt rotational grazing *** insightful findings offer policy implications on promoting grassroot NbS for ecosystem protection and resource utilization in developing pastoral countries.

关键词： grassroots nature-based solutions rotational grazing grassland quality pastoral region China

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水性耐油底漆在大型结构件上的试验

现代涂料与涂装 2024年第2期27卷 28-29+36页

作者：徐健董庆建张瑞尚付贵山推工程机械股份有限公司立邦工业涂料(上海)有限公司

通过试验手段研发出一种适用于耐高温、耐油的水性底漆，以满足环保及涂装的需要，替代油性底漆，并且保证了涂装的性能。

关键词：涂装水性耐油底漆附着力试验

Gap edge canopy buffering of throughfall deposition in a subalpine natural forest

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Forest Ecosystems 2022年第4期9卷 503-510页

作者： Siyi Tan qing dong Xiangyin Ni Kai Yue Shu Liao Fuzhong Wu Key Laboratory for Humid Subtropical Eco-Geographical Processes of the Ministry of Education School of Geographical SciencesFujian Normal UniversityFuzhou350007China Ecological Security and Protection Key Laboratory of Sichuan Province Mianyang Teachers'CollegeMianyang621000China

Base cation loads are rarely considered in forest gap edge canopies,but they can play critical roles in capturing or buffering atmospheric deposition in forests with frequent gap disturbances,such as subalpine *** selected an expanded gap edge canopy and a closed canopy in a subalpine natural forest on the eastern Tibetan *** throughfall deposition and canopy exchange processes of common base cations(K^(+),Ca^(2+),Na^(+),and Mg^(2+))were continuously studied over two *** results showed that the enrichment ratio and fluxes had lower levels of base cations in the gap-edge canopy than in the closed canopy,which indicated that base cations were concentrated more in the closed canopy than in the gap-edge *** Ca^(2+)in the gap-edge canopy showed a higher net throughfall flux,the annual net throughfall fluxes of K^(+),Na^(+) and Mg^(2+) within the gap-edge canopy were 1.83,6.75 and 2.95 times lower than those in the closed canopy,***,dry deposition fluxes of base cations significantly decreased in the gap edge canopy compared to those in the closed canopy,and the decreasing tendency was more significant during the snowy season than during the rainy ***,these results suggest that the amount of base cations in subalpine natural forest ecosystems may be overestimated when the throughfall deposition of ions in gap edge canopies is ignored.

关键词： Canopy exchange Dry deposition Throughfall Subalpine forest Precipitation deposition

替罗非班及双联抗血小板治疗超溶栓时间窗急性进展性脑梗死患者的效果

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临床和实验医学杂志 2024年第10期23卷 1013-1017页

作者：陈瑞清董育卿李鹏程李艳军边林大同市第五人民医院神经内科山西大同037006

目的分析替罗非班及双联抗血小板治疗超溶栓时间窗急性进展性脑梗死(APCI)患者的效果。方法前瞻性选取2021年12月至2022年12月大同市第五人民医院神经内科收治的超溶栓时间窗APCI患者70例,按照随机数字表法将其分为常规组和联合组,每组... 详细信息

目的分析替罗非班及双联抗血小板治疗超溶栓时间窗急性进展性脑梗死(APCI)患者的效果。方法前瞻性选取2021年12月至2022年12月大同市第五人民医院神经内科收治的超溶栓时间窗APCI患者70例,按照随机数字表法将其分为常规组和联合组,每组各35例。两组均采取常规治疗,常规组在常规治疗基础上采用阿司匹林+氯吡格雷双联抗血小板治疗,联合组在常规治疗基础上采用替罗非班+双联抗血小板治疗。比较两组的临床疗效,并对两组治疗前、治疗14 d后神经功能[采用美国国立卫生研究院卒中量表(NIHSS)评分评估]、日常生活能力[采用日常生活能力评定量表(ADL)进行评估]、炎症因子[超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)]水平以及治疗过程中的不良反应发生情况进行比较。结果联合组总有效率和常规组总有效率(91.42%vs.85.71%)比较,差异无统计学意义(P>0.05)。治疗14 d后,两组NIHSS评分均较治疗前降低,ADL评分均较治疗前升高,且联合组NIHSS评分为(4.52±1.67)分,低于常规组(6.28±1.78)分,ADL评分为(84.23±6.58分),高于常规组[(74.34±7.12)分],差异均有统计学意义(P0.05)。结论对于超溶栓时间窗急性进展性脑梗死患者,在双联抗血小板治疗的基础上联合替罗非班治疗,可取得更好的治疗效果,可以更好地改善患者的神经功能、日常生活能力以及降低炎症反应。

关键词：脑梗死替罗非班双联抗血小板神经功能日常生活能力炎症反应

执业药师培训案例库的构建及在研究生教学中的应用

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海峡药学 2024年第4期36卷 45-47页

作者：李乐邓喜玲秦冬梅王恒田卉王国庆石河子大学药学院新疆石河子832000

目的研究案例教学法在研究生教学中的应用。方法通过真实性、科学性、趣味性、有效性等原则,构建执业药师培训课程案例库,并在研究生教学过程中实践两个学期,通过学生评价,学生成绩等指标评价教学改革效果。结果案例教学法通过典型... 详细信息

目的研究案例教学法在研究生教学中的应用。方法通过真实性、科学性、趣味性、有效性等原则,构建执业药师培训课程案例库,并在研究生教学过程中实践两个学期,通过学生评价,学生成绩等指标评价教学改革效果。结果案例教学法通过典型案例的学习和讨论,启发学习者分析问题,解决问题,能够有效提升教学效果,提升学习者学习兴趣,促进理论知识与实践工作的结合,帮助学生掌握知识点,提高综合素养。结论案例教学法提升了教学效果,培养了具有较强实践能力的药学人才,具有很好的推广价值。

关键词：执业药师案例库研究生

A simple technique for suprachoroidal space injection of triamcinolone acetonide in treatment of macular edema

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International Journal of Ophthalmology(English edition) 2022年第12期15卷 2017-2021页

作者： Dan-Dan Zhang Dan-Yang Che dong-qing Zhu Department of Ophthalmology Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200001China Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology Shanghai 200001China

AIM:To introduce a simple resistance controlled suprachoroidal space(SCS)injection technique using a disposable 30-gauge needle connected to a 1 m L syringe and evaluate the effectiveness and applicability of this technique in the treatment of macular ***:A total of 20 patients with various types of macular edema were subjected to a resistance controlled SCS injection of triamcinolone acetonide(TA)with a disposable 30-gauge needle connected to a 1 m L *** technique allows the easy and smooth injection of the TA only once the tip of the needle reached the potential SCS which was indicated by the lower resistance on the *** main outcome measures were anterior segment spectral-domain optical coherence tomography(AS-OCT)measurements post-operation immediately and central subfield thickness(CST),best-corrected visual acuity(BCVA),and intraocular pressure(IOP)measurements at 3mo ***:AS-OCT examination showed the expansion of the SCS near the injection site immediately after SCS *** three months of follow-up,as compared to the baseline,the mean CST was significantly decreased from 535.0±157.24 to 319.55±127.30μm(P<0.001),the mean BCVA was significantly improved from 1.05±0.41 to 0.73±0.41 log MAR(P<0.001),and the mean IOP was not significantly different,from 15.05±2.54 to 15.85±3.60 mm Hg(P=0.185).Any complication related to the injection procedure including cataract,choroidal and retinal hemorrhage,retinal detachment,or endophthalmitis was not observed in this ***:The simple and minimally invasive technique of SCS injection of TA with a disposable 30-gauge needle connected to a 1 m L syringe is useful and applicable for macular edema.

关键词： suprachoroidal space injection needle macular edema triamcinolone acetonide

TOPK Activation Exerts Protective Effects on Cisplatin-induced Acute Kidney Injury

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Current Medical Science 2022年第4期42卷 742-753页

作者： Hui ZHANG qing-qing dong Hua-pan SHU Yu-chi TU Qian-qian LIAO Li-jun YAO Department of Nephrology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Objective:T-LAK-cell-originated protein kinase(TOPK),a PSD95-Disc large-ZO1(PDZ)binding kinase(PBK),is a novel member of the mitogen-activated protein kinase(MAPK)*** have shown that TOPK plays a critical role in the function of tumor cells,including apoptosis and ***,little is known on the effect of TOPK in cisplatin-induced acute kidney injury(CP-AKI).This study aimed to investigate the role and mechanism of TOPK in ***:Cisplatin was administered to C57BL/6 mice and cultured kidney tubular epithelial cells(TECs)to establish the CP-AKI murine or cellular *** were then stimulated with the specific inhibitor of TOPK OTS514 or transfected with the recombinant-activated plasmid TOPK-T9E to inhibit or activate *** TECs were treated with AKT inhibitorⅧfollowing stimulation with OTS514 or *** blotting and flow cytometry were used to evaluate the cell cycle and apoptosis of ***:The analysis revealed that the TOPK activity was significantly suppressed by cisplatin,both in vivo and in ***,the pharmacological inhibition of TOPK by OTS514,a specific inhibitor of TOPK,exacerbated the cisplatin-induced cell cycle arrest in the G2/M phase and apoptosis of cultured ***,the TOPK activation via the TOPK-T9E plasmid transfection could partially reverse the cell cycle arrest at the G2/M phase and apoptosis of cisplatin-treated *** addition,AKT/protein kinase B(PKB),as a TOPK target protein,was inhibited by cisplatin in cultured *** pharmaceutical inhibition of AKT further aggravated the apoptosis of TECs induced by cisplatin or TOPK *** systematically mediated the apoptosis via the AKT pathway in the CP-AKI cell ***:These results indicate that TOPK activation protects against CP-AKI by ameliorating the G2/M cell cycle arrest and cell apoptosis.

关键词： acute kidney injury cisplatin cell cycle apoptosis T-LAK-cell-originated protein kinase/PSD95-Disc large-ZO1 binding kinase

C(sp^(3))-H bond functionalization of oximes derivatives via 1,5-hydrogen atom transfer induced by iminyl radical

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Chinese Chemical Letters 2022年第3期33卷 1199-1206页

作者： Dao-qing dong Jing-Cheng Song Shao-Hui Yang Qi-Xue Qin Zu-Li Wang En-Xuan Zhang Yuan-Yuan Sun qing-qing Han Shan Yue College of Chemistry and Pharmaceutical Sciences Qingdao Agricultural UniversityQingdao 266109China Asymchem Life Science(Tianjin)Co. Ltd.Tianjin 300457China

Oximes derivatives have been vastly used in organic synthesis. In this review, C(sp^(3))-H bond functionalization of oximes derivatives via iminyl radical induced 1,5-hydrogen atom transfer was discussed. According to the different type of products, this review was divided into three parts: (1) C(sp^(3))-H bond functionalization for C-C bond formation. (2) C(sp^(3))-H bond functionalization for C-N bond formation. (3) C(sp^(3))-H bond functionalization for C-S, C-F bond formation.

关键词： Oximes derivatives 1 5-hydrogen atom transfer Iminyl radicals C(sp^(3))-H Bond Visible light