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Endoscopic bilateral stent-in-stent placement for malignant hilar obstruction using a large cell type stent

Hepatobiliary & Pancreatic Diseases International 2016年第6期15卷 633-639页

作者： Jin Myung Park Sang Hyub Lee Kwang hyun Chung dong Kee Jang Ji Kon Ryu Yong-Tae Kim Jae Min Lee Woo hyun Paik Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of Medicine Department of Internal Medicine Kangwon National University HospitalKangwon National University School of Medicine Department of Internal Medicine Gyeongsang National University HospitalGyeongsang National University College of Medicine Department of Internal Medicine Inje University Ilsan Paik Hospital

BACKGROUND： Bilateral stent-in-stent （SIS） self-expandable metal stent placement is technically chghallenging for palliation of unresectable malignant hilar obstruction. In the SIS technique, the uniform large cell type biliary stent facilitates contralateral stent deployment through the mesh of the first metallic stent. This study aimed to assess the technical success and clinical effectiveness of this technique with a uniform large cell type biliary stent. METHODS： Thirty-one patients who underwentlbilateral SIS placement using a large cell type stent were reviewed retrospectively. All patients showed malignant hilarl obstruction （Bismuth types Ⅱ, Ⅲ, Ⅳ） with different etiologies. RESULTS： Sixteen （51.6%） patients were male. The mean age of the patients was 67.0±14.0 years. Most patients were diagnosed as having hilar cholangiocarcinoma （58.1%） and gallbladder cancer （29.0%）. Technical success rate was 83.9%. Success was achieved more frequently in patients without masses obstructing the biliary confluence （MOC） than those with MOC （95.2% vs 60.0%, P=0.03）. Functional success rate was 77.4%. Complications occurred in 29.0% of the patients. These tended to occur more frequently in patients with MOC （50.0% vs 19.0%, P=0.11）. Median time to recurrent biliary obstruction was 188 days and median survival was 175 days. CONCLUSIONS： The large cell type stent can be used efficiently for bilateral SIS placement in malignant hilar obstruction. However, the risk of technical failure increases in patients with MOC, and caution is needed to prevent complications for these patients.

关键词： biliary tract disease cholangiocarcinoma endoscopic biliary drainage stent insertion

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In situ cardiac regeneration by using neuropeptide substance P and IGF-1C peptide eluting heart patches

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Regenerative Biomaterials 2018年第5期5卷 303-316页

作者： Muhammad Shafiq Yue Zhang Dashuai Zhu Zongxian Zhao dong-Hwee Kim Soo hyun Kim Deling Kong Division of Bio-Medical Science&Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Bioactive Materials of Ministry of EducationCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)College of Life ScienceNankai UniversityTianjin 300071China Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and TechnologyCheongryangSeoul 130-650Republic of Korea Department of Chemistry Center for Tissue Engineering&Regenerative MedicinePakistan Institute of Engineering&Applied Sciences(PIEAS)NiloreIslamabad 45650Pakistan Department of Physiology&Pathophysiology Tianjin Medical UniversityTianjin 300070China KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul 02841Republic of Korea

Cardiovascular diseases cause huge socio-economic burden *** a mammalian myocardium has its own limited healing capability,scaffold materials capable of releasing stem cell recruiting/engrafting factors may facilitate the regeneration of the infarcted *** aim of this research was to develop cardiac patches capable of simultaneously eluting substance P(SP)and insulin-like growth factor-1C(IGF-1C)***/collagen type 1-based patches with or without SP and IGF-1C peptide were fabricated by co-electrospinning,which exhibited nanofibrous *** and IGF-1C/SP patches recruited significantly higher numbers of bone marrow-mesenchymal stem cells than that of the negative control and patch-only groups in *** developed patches were transplanted in an infarcted myocardium for up to 14 *** underwent left anterior descending artery ligation and received one of the following treatments:(i)sham,(ii)saline,(iii)patch-only,(iv)IGF-1C patch,(v)SP patch and(vi)IGF-1C/SP *** and IGF-1C/SP patch-treated groups exhibited better heart function and attenuated adverse cardiac remodeling than that of the saline,patch-only and individual peptide containing cardiac *** patch and IGF-1C/SP patch-treated groups also showed higher numbers of CD31-positive vessels and isolectin B4-positive capillaries than that of other ***-1C/SP-treated group also showed thicker left ventricular wall in comparison to the saline and patch-only ***,IGF-1C/SP patches recruited significantly higher numbers of CD29-positive cells and showed less numbers of Tunel-positive cells compared with the other *** data suggest that SP and IGF-1C peptides may act synergistically for in situ tissue repair.

关键词： cardiac patch stem cell recruitment myocardial infarction electrospinning

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Optical Properties of Laterally Aligned Si Nanowires for Transparent Electronics Applications

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Nano Research 2011年第9期4卷 817-823页

作者： dong hyun Lee Jaeseok Yi Won Woo Lee Ungyu Paik John A. Rogers Won II Park Division of Materials Science and Engineering Hanyang University Seoul 133-791 Korea Department of Energy Engineering Hanyang University Seoul 133-791 Korea Department of Materials Science and Engineering Department of Chemistry Department of Mechanical Science and Engineering Beckman Institute and Frederick Seitz Materials Research Laboratory University of Illinois at Urbana-Champaign Urbana Illinois 61801 USA

We have investigated the optical properties of laterally aligned Si nanowire （SiNW） arrays in order to explore their potential applicability in transparent electronics. The SiNW array exhibited good optical transparency in the visible spectral range with a transmittance of -90% for a NW density of -20-25 per 10 μm. In addition, polarization-dependent measurements revealed a variation in transmittance in the range of 80%-95% depending on the angle between the polarization of incident light and the NW axis. Using the SiNWs, we demonstrated that transparent transistors exhibit good optical transparency （greater than 80%） and showed typical p-type SiNW transistor characteristics.

关键词： Si nanowire optical properties transparent thin film transistor finite-difference time-domain (FDTD) modeling

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Neuromorphic devices based on fluorite-structured ferroelectrics

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InfoMat 2022年第12期4卷 1-32页

作者： dong hyun Lee Geun Hyeong Park Se hyun Kim Ju Yong Park Kun Yang Stefan Slesazeck Thomas Mikolajick Min Hyuk Park Department of Materials Science and Engineering&Inter-University Semiconductor Research Center College of EngineeringSeoul National UniversitySeoulRepublic of Korea Research Institute of Advanced Materials Seoul National UniversitySeoulRepublic of Korea NaMLab gGmbH DresdenGermany Institute of Engineering Research Seoul National UniversitySeoulRepublic of Korea

A continuous exponential rise has been observed in the storage and processing of the data that may not curtail in the foreseeable *** required data processing speed and power consumption are restricted by the buses between the logic and memory devices that are characteristic of the von Neumann computing ***-mimicking neuromorphic computing has garnered considerable academic and industrial interest to resolve these ***,devices based on emerging nonvolatile memories capable of mimicking the behaviors of synapses and neurons,which are the main elements in biological computing systems(brains),are attracting significant interest from the device *** the discovery of ferroelectricity in fluorite-structured oxides,such as HfO2 and ZrO2,which are compatible with the state-of-the-art complementary-metal-oxide-semiconductor processes,ferroelectric devices have rapidly evolved as the main direction of these research and development *** science related to fluorite-structured ferroelectrics has been intensively studied over the last *** present,the focus is gradually moving to practical applications,including neuromorphic computing and advanced classical processing or memory units in the conventional von Neumann ***,despite its rapid development,the wealth of recent progress in neuromorphic computing devices based on fluorite-structured ferroelectrics has not been reviewed and *** progress report comprehensively reviews and systemizes the recent progress in artificial synaptic and spiking neuron devices for neuromorphic computing based on fluorite-structured ferroelectrics.

关键词： ferroelectrics hafnia neuromorphic computing semiconductor devices

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Reefs in the Early Paleozoic Taebaek Group,Korea:A Review

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Acta Geologica Sinica(English Edition) 2016年第1期90卷 352-367页

作者： LEE Jeong-hyun HONG Jongsun WOO Jusun OH Jae-Ryong LEE dong-Jin CHOH Suk-Joo Department of Earth and Environmental Sciences Korea University Department of Earth and Planetary Sciences University of Tennessee Division of Polar Earth-System Sciences Korea Polar Research Institute Department of Earth and Environmental Sciences Andong National University

Various early Paleozoic （Cambrian Series 3-Middle Ordovician） reefs are found in the Taebaek Group, eastern Korea, located in the eastern margin of the Sino-Korean Block. They occur in every carbonate-dominant lithostratigraphic unit of the group, but their morphology and composition differ markedly. The Daegi Formation （middle Cambrian： Cambrian Series 3） contains siliceous sponge-Epiphyton reefs formed in a shallow subtidal environment, which is one of the earliest metazoan-bearing microbial reefs after the archaeocyath extinction. The Hwajeol Formation （upper Cambrian： Furongian） encloses sporadic dendrolites consisting of Angulocellularia, which developed in a relatively deep subtidal environment, representing a rare deeper water example. The onset of the Ordovician radiation resulted in the formation of microbialite-Archaeoscyphia-calathiid patch reefs in shallow subtidal deposits of the Lower Ordovician Dumugol Formation. Subsequent late Early Ordovician relative sea-level fall established extensive peritidal environments, forming microbial mats and stromatolites of the Lower-Middle Ordovician Makgol Formation. Ensuing Ordovician radiation resulted in one of the earliest metazoan skeletal reefs of the Middle Ordovician Duwibong Formation, constructed by stromatoporoid Cystostroma and bryozoan Nicholsonella, and developed around shallow shoals. These reefs reflect ongoing evolution and sea-level change during the early Paleozoic, and exemplify a rare glimpse of peri-Gondwanan records of reef evolution, which warrant detailed investigations and comparison with their counterparts in other regions.

关键词： carbonate sedimentology metazoans stromatolites Porifera Cambrian-Ordovician Taebaeksan Basin Korea

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The Sensing Behavior to Volatile Organic Compounds Gas on Polypyrrole Sensor under Humidity Condition

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稀有金属材料与工程 2006年第A3期35卷 65-66页

作者： Jae-hyun Cho Joon-Boo Yu Sung-Ok Sohn Duk-dong Lee Jeung-Soo Huh Department of Material Science Metallurgy Kyungpook National UniversitySangyuk-Dong 1370DaeguKorea School of Electronic Engineering Kyungpook National UniversitySangyuk-Dong 1370DaeguKorea

Polypyrrole (PPy) powder was synthesized by chemical polymerization at 0℃under atmospheric condition and its layer was prepared by dip coating method on the alumina substrate with interdigitated *** influence of relative humidity (RH 0～70%) to PPy sensor was *** measuring temperature was fixed at 25℃.Methanol and benzene were used as target *** analytic techniques were examined to observe changes in the properties of PPy *** sensitivity of PPy sensor to water vapor was linearly increased with the increasing *** the relative humidity increase from 0% to 70%,the sensitivities to methanol and benzene vapor were reduced,and reduction ratio of sensitivity was 94%, 92.5% at RH 70%,respectively.

关键词： VOCs polypyrrole humidity effect gas sensor

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Cytomegalovirus colitis induced segmental colonic hypoganglionosis in an immunocompetent patient: A case report

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World Journal of Clinical Cases 2021年第20期9卷 5631-5636页

作者： Ban Seok Kim Seon-Young Park dong hyun Kim Nah Ihm Kim Jae hyun Yoon Jae Kyun Ju Chang Hwan Park hyun Soo Kim Sung Kyu Choi Department of Gastroenterology Chonnam National University HospitalGwangju 501-757South Korea Department of Pathology Chonnam National University HospitalGwangju 501-757South Korea Department of Surgery Chonnam University HospitalGwangju 501-757South Korea

BACKGROUND Cytomegalovirus(CMV)colitis is usually seen in immunocompromised patients with risk factors such as human immunodeficiency virus infection,solid organ transplant,inflammatory bowel disease,or ***,many clinicians usually do not consider the possibility of CMV colitis in immunocompetent *** reported a rare case of segmental colonic hypoganglionosis associated with CMV colitis in an immunocompetent *** SUMMARY A 48-year-old woman with no underlying disease was admitted to our hospital for severe abdominal pain and *** tomography of the abdomen showed diffuse dilatation of the small intestine and the entire *** sigmoidoscopic findings and result of polymerase chain reaction(PCR)for CMV revealed the compatible findings of CMV colitis,the patient was treated with intravenous *** treatment,sigmoidoscopic findings and CMV PCR results *** the patient continued to suffered from *** months after the initial admission,patient visited the emergency department with severe abdominal pain and imaging revealed aggravation of fecal impaction and bowel *** performed subtotal colectomy to control patient’s *** examination of the resected specimen showed significantly reduced number of mature ganglion cells in the sigmoid colon compared to that in the proximal *** Our case demonstrates that CMV colitis can develop even in patients with no other underlying disease,and that CMV colitis can be one of the causes for developing colonic hypoganglionosis.

关键词： Colonic pseudo-obstruction Colitis Cytomegalovirus Ganglia Case report

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Heterostructures in two-dimensional colloidal metal chalcogenides:Synthetic fundamentals and applications

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Nano Research 2019年第8期12卷 1750-1769页

作者： Yuho Min Eunmi Im Geon-Tae Hwang Jong-Woo Kim Cheol-Woo Ahn Jong-Jin Choi Byung-dong Hahn Joon-Hwan Choi Woon-Ha Yoon dong-Soo Park dong Choon hyun Geon Dae Moon Functional Ceramics Department Powder & Ceramics DivisionKorea Institute of Materials Science (KIMS)ChangwonGyeongnam51508Republic of Korea Department of Polymer Science and Engineering Kyungpook National UniversityDaegu41566Republic of Korea dongrtam Regional Division Korea Institute of Industrial TechnologyBusan46938Republic of Korea

As a new class of two-dimensional materials, two-dimensional (2D) heterostructures constructed from metal chalcogenides (MCs) have been gaining tremendous attention due to their unprecedented physical and chemical phenomena, mainly originated from their distinct structural features such as composition, architecture type, spatial arrangement of each component, crystal structure, exposed facet and interface, dimensionality in their heterostructures. Towards the realization of practical applications, synthetic approaches need a rational design with a variety of architecture types including laterally-combined, vertically-aligned, and conformally-coated 2D MC heterostructures. Among various synthetic routes, solution-based synthesis is thought of as an alternative to fabrication through high-cost setups since it can control those structural features in a cheap fashion. This review presents recent progress on solution-based synthesis to produce various 2D MC heterostructures with a focus on the synthetic fundamentals in terms of thermodynamic and kinetic aspects related to the growth mechanism. Four different synthetic approaches are reviewed: seeded growth, cation exchange reaction, colloidal atomic layer deposition, direct synthesis including one-step process and modified electrochemical method. We also provide some representative applications of 2D MC heterostructures and their hybrid composites in various fields including optoelectronics, thermoelectrics, catalysis, and battery. Finally, we offer an insight into challenges and future directions in a synthetic improvement of 2D MC heterostructures.

关键词： metal chalcogenide heterostructure anisotropic nanomaterials two-dimensional (2D) nanomaterials solution-based synthesis

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Hydrodynamics of air-kerosene bubble column under elevated pressure in homogeneous flow regime

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Chinese Journal of Chemical Engineering 2021年第5期34卷 190-202页

作者： Bay Van Tran Son Ich Ngo Young-Il Lim Keon Bae dong hyun Lee Kang-Seok Go Nam-Sun Nho Center of Sustainable Process Engineering(CoSPE) Department of Chemical EngineeringHankyong National UniversityGyeonggi-doAnseong-siJungang-ro 32717579Republicof Korea School of Chemical Engineering Sungkyunkwan University2066 Seobu-roJanganSuwon 16419Republic of Korea Center for Convergent Chemical Process(CCP) 141 Gajeong-roYuseong-guDaejeon 34114Republic of Korea

A multiphase computational fluid dynamics(CFD)model coupled with the population balance equation(PBE)was developed in a homogeneous air-kerosene bubble column under elevated pressure(P).The specific pressure drop(ΔP/L),gas holdup(α_(G)),and Sauter mean diameter(d_(32))were experimentally measured in the bubble column with 1.8 m height and 0.1 m inner diameter,which was operated at a superficial gas velocity of 12.3 mm·s^(-1),and P=1-35 bar(1 bar=10^(5) Pa).A modified drag coefficient model was proposed to consider the effect of bubble swarm and pressure on hydrodynamics of the bubble *** Luo breakage model was modified to account for liquid density,viscosity,surface tension and gas ***ΔP/L,α_(G),and d_(32) obtained from the CFD model were compared with experimental data,and the gas density-dependent parameters of the CFD model were *** increasing P from 1 to 35 bar,theα_(G) varied from 5.4%to 7.2% and the d32 decreased from 2.3 to 1.5 *** CFD-PBE model is applicable to predict hydrodynamics of pressurized bubble columns for gas-organic liquid in the homogeneous regime.

关键词： Bubble column Air-kerosene High pressure Homogenous regime Computational fluid dynamics (CFD) Population balance equation (PBE)

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Effect of gadolinium incorporation on optical characteristics of YNbO_4:Eu^(3+) phosphors for lamp applications

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Journal of Rare Earths 2012年第3期30卷 205-209页

作者： Sung Hwan Choi G. Anoop dong Wook Suh Kyung Pil Kim hyun Ju Lee Jae Soo Yoo Display Materials Laboratory School of Chemical Engineering and Materials Science Chung-Ang University

Eu3＋-doped （Y,Gd）NbO4 phosphor was synthesized by solid-state reaction for possible application in cold cathode fluorescent lamps. A broad absorption band with peak maximum at 272 nm was observed which was due to the charge transfer between Eu3＋ ions and neighboring oxygen anions. A deep red emission at the peak wavelength of 612 nm was observed which could be attributed to the 5D0→7F2 transition in Eu3＋ ions. The highest luminance for Y1-x-yGdyNbO4：Eux3＋ under 254 nm excitation was achieved at Eu3＋ concentration of 18 mol.% （x=0.18） and Gd3＋ concentration of 8.2 mol.% （y=0.082）. The luminance of Y0.738Gd0.082NbO4：Eu3＋0.18 was higher than that of a typical commercial phosphor Y2O3：Eu3＋ and the CIE chromaticity coordinate was （0.6490, 0.3506）, which was deeper than that of Y2O3：Eu3＋. The particle size of the synthesized phosphors was controlled by the NaCl flux and particle size as high as 8 μm with uniform size distribution of particles was obtained.

关键词： YNbO4:Eu oxide phosphors rare earths

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