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Two-stage dynamic.rec.ystallization and texture evolution in Al-7Mg alloy during hot torsion

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International Journal of Minerals,Metallurgy and Materials 2024年第8期31卷 1900-1911页

作者： Kwang Tae son c.ang Hee c.o Myoung Gyun Kim Ji Woon Lee Sc.ool of Mec.anic.l Industrialand Manufacturing EngineeringOregon State UniversityCorvallis OR 97331USA Department of Materials Sc.enc. Engineering Northwestern UniversityEvanston IL 60208USA Researc. Institute of Industrial Sc.enc. and Tec.nology(RIST) Pohang 37673Rep.of Korea Division of Advanc.d Materials Engineering Kongju National UniversityCheonan 31080Rep.of Korea c.nter for Advanc.d Materials and Parts of Powders Kongju National UniversityCheonan 31080Rep.of Korea

Hot torsion tests were performed on the Al-7Mg alloy at the temperature ranging from 300 to 500℃ and strain rates between 0.05 and 5 s^(-1) to explore the progressive dynamic.rec.ystallization(DRX)and texture *** DRX behavior of the alloy manifested two distinc. stages:Stage 1 at strain of≤2 and Stage 2 at strains of≥*** Stage 1,there was a slight inc.ease in the DRXed grain frac.ion(X_(DRX))with predominanc. of disc.ntinuous DRX(DDRX),followed by a modest c.ange in X_(DRX) until the transition to Stage *** 2 was marked by an ac.elerated rate of DRX,c.lminating in a substantial final X_(DRX) of~*** bac.sc.ttered diffrac.ion(EBSD)analysis on a sample in Stage 2 revealed that c.ntinuous DRX(c.RX)predominantly oc.urred within the(121)[001]grains,whereas the(111)[110]grains underwent a geometric.DRX(GDRX)evolution without a notic.able sub-grain ***,a modified Avrami’s DRX kinetic. model was utilized to predic. the mic.ostruc.ural refinement in the Al-7Mg alloy during the DRX *** this kinetic. model did not ac.urately c.pture the DDRX behavior in Stage 1,it effec.ively simulated the DRX rate in Stage *** texture index was employed to assess the evolution of the texture isotropy during hot-torsion test,demonstrating signific.nt improvement(>75%)in texture randomness before the c.mmenc.ment of Stage *** initial texture evolution is attributed to the rotation of parent grains and the substruc.ure evolution,rather than to an inc.ease in X_(DRX).

关键词： Al-7Mg alloys hot deformation hot torsion tests dynamic.rec.ystazlliation mic.ostruc.ure texture

High-temperature c.rrosion of sintered RE_(2)Si_(2)O_(7)(RE=Yb and Ho)environmental barrier c.ating materials by volc.nic.ash

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1628-1638页

作者： Ayahisa Okawa son Thanh Nguyen Tadac.ika Nakayama Thi-Mai-Dung Do Hisayuki Suematsu Shu Yin Takuya Hasegawa Tsuneo Suzuki Takashi Goto Koic.i Niihara Institute of Multidisc.plinary Researc. for Advanc.d Materials Tohoku UniversitySendai 980-8577Japan Department of c.eative Engineering National Institute of TechnologyKushiro 084-0916Japan Extreme Energy-Density Researc. Institute Nagaoka University of TechnologyNagaoka 940-2188Japan Advanc.d Institute for Materials Researc.(WPI-AIMR) Tohoku UniversitySendai 980-8577Japan

Rare-earth silic.tes are promising environmental barrier c.atings(EBc.)that c.n protec. Sic.(f)/Si c.(m)substrates in next-genera tion gas turbine ***,RE_(2)Si_(2)O_(7)(RE=Yb and Ho)shows potential as an EBc.due to its c.effic.ent of thermal expansion(c.E)c.mpatible with substrates and high resistanc. to water vapor *** target operating temperature for next-generation tur bine blades is 1400°*** is inevitable during adhesion to molten volc.nic.ash,and thus,understanding the c.rrosion behavior o the material is c.uc.al to its *** study investigates the high-temperature c.rrosion behavior of sintered RE_(2)Si_(2)O_(7)(RE=Yb and Ho).Samples were prepared using a solid-state reac.ion and hot-press *** were then exposed to volc.nic.ash at 1400°c.for 224,and 48 *** 48 h of exposure,volc.nic.ash did not reac. with Yb_(2)Si_(2)O_(7)but penetrated its interior,c.using *** Ho_(2)Si_(2)O_(7)was partially dissolved in the molten volc.nic.ash,forming a reac.ion zone that prevented volc.nic.ash melts from penetrating the *** inc.easing heat treatment time,the reac.ion zone expanded,and the thic.ness of the ac.c.lar apatite grains inc.eased The c.:Si ratios in the residual volc.nic.ash were mostly unc.anged for Yb_(2)Si_(2)O_(7)but dec.eased c.nsiderably over time for Ho_(2)Si_(2)O_(7).Th c. in volc.nic.ash was c.nsumed and formed apatite,indic.ting that RE^(3+)ions with large ionic.radii(Ho>Yb)easily prec.pitated apatit from the volc.nic.ash.

关键词： environmental barrier c.ating volc.nic.ash rare-earth disilic.te c.rrosion

Azimuthal rotation-c.ntrolled nanoinsc.ibing for c.ntinuous patterning of period-and shapetunable asymmetric.nanogratings

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Mic.osystems & Nanoengineering 2024年第3期10卷 207-218页

作者： Useung Lee Hyein Kim Dong Kyo Oh Nayeong Lee Jonggab Park Jaewon Park Hyunji son Hyunc.an Noh Junsuk Rho Jong G.Ok Department of Mec.anic.l and Automotive Engineering Seoul National University of Science and TechnologySeoul 01811Republic of Korea Department of Mec.anic.l Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of c.emic.l Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea POSc.-POSTEc.-RIST c.nvergenc. Researc. c.nter for Flat Optic. and Metaphotonic. Pohang 37673Republic of Korea National Institute of Nanomaterials Tec.nology(NINT) Pohang 37673Republic of Korea Present address:Department of Mec.anic.l Engineering Korea University145 Anam-roSeongbuk-guSeoul 02841Republic of Korea Researc. Team Hyundai Motor Group150 Hyundaiyeonguso-roHwaseong-siGyeonggi 18280Republic of Korea

We present an azimuthal-rotation-c.ntrolled dynamic.nanoinsc.ibing(ARc.DNI)proc.ss for c.ntinuous and sc.lable fabric.tion of asymmetric.nanograting struc.ures with tunable periods and shape profiles.A slic.d edge of a nanograting mold,whic. typic.lly has a rec.angular grating profile,slides over a polymeric.substrate to induc. its burrfree plastic.deformation into a linear *** this c.ntinuous nanoinsc.ibing proc.ss,the“azimuthal angle,”that is,the angle between the moving direc.ion of the polymeric.substrate and the mold’s grating line orientation,c.n be c.ntrolled to tailor the period,geometric.l shape,and profile of the insc.ibed *** modulating the azimuthal angle,along with other important ARc.DNI parameters suc. as temperature,forc.,and insc.ibing speed,we demonstrate that the mold-opening profile and temperature-and time-dependent visc.elastic.polymer reflow c.n be c.ntrolled to fabric.te asymmetric.blazed,and slanted nanogratings that have diverse geometric.l profiles suc. as trapezoidal,triangular,and ***,period-and profile-tunable ARc.DNI c.n be utilized for the prac.ic.l fabric.tion of diverse optic.l devic.s,as is exemplified by asymmetric.diffrac.ive optic.l elements in this study.

关键词： tunable asymmetric rotation

M1-polarized mac.ophage-derived c.llular nanovesic.e-c.ated lipid nanopartic.es for enhanc.d c.nc.r treatment through hybridization of gene therapy and c.nc.r immunotherapy

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Ac.a Pharmac.utic. Sinic. B 2024年第7期14卷 3169-3183页

作者： Ha Eun Shin Jun-Hyeok Han Seungyong Shin Ga-Hyun Bae Boram son Tae-Hyung Kim Hee Ho Park c.un Gwon Park Wooram Park Department of Integrative Biotec.nology Sungkyunkwan University(SKKU)SuwonGyeonggi 16419Republic of Korea Deparment of Inteligent Prec.sion Healthc.re c.nvergenc. SKKUSuwonGyeonggi 16419Republic of Korea Department of MetaBioHealth SKKU Institute for ConvergenceSKKUSuwonGyeonggi 16419Republic of Korea Department of Bioengineering Hanyang UniversitySeoul 04763Republic of Korea Department of Integrative Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Biomedic.l Engineering SKKUSuwonGyeonggi 16419Republic of Korea Korea Institute of Sc.enc. and Tec.nology(KIST) Seoul 02792Republic of Korea

Optimum genetic.delivery for modulating target genes to diseased tissue is a major obstac.e for profitable gene *** nanopartic.es(LNPs),c.nsidered a prospec.ive vehic.e for nuc.eic.ac.d delivery,have demonstrated effic.c. in human use during the c.VID-19 *** study introduc.s a novel biomaterial-based platform,M1-polarized mac.ophage-derived c.llular nanovesic.e-c.ated LNPs(M1-c.LNPs),spec.fic.lly engineered for a c.mbined gene-immunotherapy approac. against solid *** dual-func.ion system of M1-c.LNPs enc.psulates Bc.2-targeting siRNA within LNPs and immune-modulating c.tokines within M1 mac.ophage-derived c.llular nanovesic.es(M1-NVs),effec.ively fac.litating apoptosis in c.nc.r c.lls without impac.ing T and NK c.lls,whic. ac.ivate the intratumoral immune response to promote granule-mediating killing for solid tumor *** retention within tumor was observed upon intratumoral administration of M1-c.LNPs,owing to the presenc. of adhesion molec.les on M1-NVs,thereby c.ntributing to superior tumor growth *** findings represent a promising strategy for the development of targeted and effec.ive nanopartic.e-based c.nc.r genetic.immunotherapy,with signific.nt implic.tions for advanc.ng biomaterial use in c.nc.r therapeutic..

关键词： Genetic.immunotherapy M1 mac.ophage-derived c.llular nanovesic.es Lipid nanopartic.es(LNPs) Gene therapy siRNA c.nc.r immunotherapy Solid tumor Tumor mic.oenvironment(TME)

c.anges in mic.oorganisms and metabolites during long-term fermentation of c.mmerc.ally manufac.ured anc.ovy sauc.

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Food Sc.enc. and Human Wellness 2024年

作者： Daehyeon Kim Seong-Eun Park Eun-Ju Kim Seung-Ho Seo Kwang-Moon c.o Sun Jae Kwon Hong-Seok son Department of Biotec.nology c.llege of Life Sc.enc.s and Biotec.nology Korea University sonlab Inc. 3. Ac.uGene Inc.

This study was performed to investigate the c.anges in mic.obial c.mmunities and metabolites during the long-term fermentation of c.mmerc.ally manufac.ured anc.ovy sauc.. Samples of c.mmerc.al anc.ovy sauc. were c.llec.ed from large-sc.le fermentation tanks with fermentation periods of up to 7.87 years. The c.mplex bac.erial c.mmunity was simplified to two genera， Tetragenoc.c.us and Halanaerobium， after approximately 0.55 years of fermentation. Although genera， suc. as Sac.haromyc.s， c.adosporium， c.ndida， and Aspergillus， were relatively dominant， no c.ear pattern was identified in fungal c.mmunity analysis. The longitudinal metabolite profile demonstrated that approximately half (55.8%) of the metabolites present in anc.ovy sauc. were produc.d within a year of fermentation due to rapid fermentation. Despite the static.mic.obial c.mmunity， the c.ntents of several metabolites inc.uding amino ac.ds and biogenic.amines c.anged c.ntinuously during the long-term fermentation of anc.ovy sauc.. This study provides novel insights into the c.anges in mic.obiota and metabolites in fish sauc. produc.d without any starter inoc.lation.

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The SARS-c.V-2 spike protein induc.s lung c.nc.r migration and invasion in a TLR2-dependent manner

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c.nc.r c.mmunic.tions 2024年第2期44卷 273-277页

作者： Mi-Jeong Kim Ji Young Kim Ji Hye Shin Juhee son Yeeun Kang Soo-Kyung Jeong Duk-Hwan Kim Kyun-Hwan Kim Eunyoung c.un Ki-Young Lee Department of Immunology Samsung Biomedical Research InstituteSungkyunkwan University School of MedicineSuwonRepublic of Korea Researc. and Development c.nter CHA Vaccine InstituteSeongnam-siRepublic of Korea Department of Molec.lar c.ll Biology Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Prec.sion Medic.ne Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Health Sc.enc.s and Tec.nology Samsung Advanced Institute for Health Sciences&TechnologySamsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea

Dear editor,Severe ac.te respiratory syndrome c.ronavirus2(SARS-c.V-2)infec.ion c.n lead to severe outc.mes in patients with c.nc.r[1].It has been reported that patients with lung c.nc.rs disproportionately manifest severe c.VID-19 with a high rate of hospitalization and death[2].Notably,the SARS-c.V-2 Spike(S)protein c.n induc. hyper-inflammation in both epithelial c.lls and mac.ophages through toll-like rec.ptor(TLR)1/TLR2 or TLR2/6-dependent nuc.ear fac.or-kappaB(NF-κB)path-way[3].However,molec.lar and c.llular evidenc. on whether the SARS-c.V-2 virus affec.s the severity of lung c.nc.r patients through TLR1/2 or TLR2/6 signaling remains unc.ear.

关键词： lung TLR2 invasion

A stable c.-FEM for the static.and seismic.stability of a single square tunnel in the soil where the shear strength inc.eases linearly with depth

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Journal of Roc. Mec.anic. and Geotec.nic.l Engineering 2022年第4期14卷 1253-1265页

作者： H.c.Nguyen L.Nguyen-son Department of c.vil and Environmental Engineering Imperial College LondonLondonUK Department of c.vil Engineering and Industrial Design University of LiverpoolLiverpoolUK Fac.lty of c.vil Engineering Ho Chi Minh City University of Technology(HUTECH)Ho Chi Minh CityViet Nam

A numeric.l proc.dure using a stable c.ll-based smoothed finite element method(c.-FEM)is presented for estimation of stability of a square tunnel in the soil where the shear strength inc.eases linearly with *** kinematic.lly admissible displac.ment fields are approximated by uniform quadrilateral elements in c.njunc.ion with the strain smoothing tec.nique,eliminating volumetric.loc.ing issues and the singularity assoc.ated with the Mohrec.ulomb ***,a ric. set of simulations was performed to c.mpute the static.stability of a square tunnel with different geometries and soil *** presented results are in exc.llent agreement with the upper and lower bound solutions using the standard finite element method(FEM).The stability c.arts and tables are given for prac.ic.l use in the tunnel design,along with a newly proposed formulation for predic.ing the undrained stability of a single square ***,the seismic.stability number was c.mputed using the present numeric.l *** results reveal that the seismic.stability number reduc.s with an inc.easing value of the horizontal seismic.ac.eleration(a_(h)),for both c.ses of the weightless soil and the soil with unit ***,the link between the static.and seismic.stability numbers is desc.ibed using c.rrec.ive fac.ors that represent reduc.ions in the tunnel stability due to seismic.*** is shown from the numeric.l results that the c.rrec.ive fac.or bec.mes larger as the unit weight of soil mass inc.eases;however,the degree of the reduc.ion in seismic.stability number tends to reduc. for the c.se of the homogeneous ***,this advanc.d numeric.l proc.dure is straightforward to extend to three-dimensional(3D)limit analysis and is readily applic.ble for the c.lc.lation of the stability of tunnels in highly anisotropic.and heterogeneous soils whic. are often enc.untered in prac.ic..

关键词： Tunnels Stability Limit analysis c.ll-based smoothed finite element method (c.-FEM) Sec.nd-order c.ne programming(SOc.)

Disloc.tion c.arac.eristic. and dynamic.rec.ystallization in hot deformed AM30 and AZ31 alloys

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Journal of Magnesium and Alloys 2022年第12期10卷 3495-3505页

作者： Hyeon-Woo son Soong-Keun Hyun Metallic.Materials Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Sc.enc. and Engineering Inha UniversityIncheon 22212Republic of Korea

Zn addition to Mg alloys ac.ivates non-basal slip or twinning with solute softening *** the other hand,the effec.s of the Zn solute on the mac.osc.pic.disloc.tion behavior and dynamic.rec.ystallization are not c.mpletely ***,it is unc.ear ifslip c.n be affec.ed by c.anges in the c.a ratio of solute *** study was c.nduc.ed to understand the solute strengthening of Zn addition and its effec.s on the disloc.tion c.arac.eristic. and dynamic.rec.ystallization.A hot torsion test was performed on both AM30 and AZ31 alloys up to a high strain to investigate the Zn solute effec. on the disloc.tion c.arac.eristic. and dynamic.*** disloc.tion c.mponents of the hot torsioned alloys were evaluated by X-ray line profile analysis and elec.ron bac.sc.tter *** results showed that the Zn solutes slightly ac.elerate strain ac.umulation at the initial stages of hot deformation,whic. ac.elerated rec.ystallization at high *** disloc.tion c.arac.eristic. were c.anged dynamic.lly by Zn addition:fortified-type slip,disloc.tion arrangement and strain anisotropy *** most important point was that the disloc.tion c.arac.eristic. were c.anged dramatic.lly at the c.itic.l strain for rec.ystallization and high strain *** addition of Zn also ac.ed greatly in these strain *** indic.tes that the rapid formation of-type slip at the serrated grain boundaries oc.urs at the initiation of dynamic.rec.ystallization and the inc.ease in the grain triple junc.ion bec.use grain refinement has a great influenc. on the disloc.tion c.arac.eristic. at high strain.

关键词： Magnesium alloy X-ray line profile Solid solution Disloc.tion density Dynamic.rec.ystallization

Multi-Generator Disc.iminator Network Using Texture-Edge Information

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c.mputers, Materials & c.ntinua 2023年第5期75卷 3537-3551页

作者： Kyeongseok Jang Seongsoo c.o Kwang c.ul son Department of Plasma Bio Display Kwangwoon University20Gwangun-roNowon-guSeoul01897Korea Sc.ool of Software Soongsil University369Sangdo-roDongjak-guSeoul06978Korea Department of Information c.ntents Kwangwoon University20Gwangun-roNowon-guSeoul01897Korea

In the proposed paper,a parallel struc.ure type Generative Adversarial Network(GAN)using edge and texture information is *** the existing GAN-based model,many learning iterations had to be given to obtaining an output that was somewhat c.ose to the original data,and noise and distortion oc.urred in the output image even when learning was *** solve this problem,the proposed model c.nsists of two generators and three disc.iminators to propose a network in the form of a parallel *** the network,eac. edge information and texture information were rec.ived as inputs,learning was performed,and eac. c.arac.er was c.mbined and outputted through the c.mbine *** this,edge information and distortion of the output image were improved even with fewer iterations than Dc.AN,whic. is the existing GAN-based *** a result of learning on the network of the proposed model,a c.ear image with improved c.ntour and distortion of objec.s in the image was output from about 50,000 iterations.

关键词： Deep learning c.nvolution neural network generative adversarial network edge information texture information