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Fungal Diversity 2012年第6期57卷 84-146页

作者： donald m.walker Lisa A.Castlebury Amy Y.Rossman Luis C.mejía James F.White Department of Natural Sciences The University of FindlayFindlayOH 45840USA Systematic mycology&microbiology Laboratory USDA Agricultural Research ServiceBeltsvilleMD 20705USA Smithsonian Tropical Research Institute Apartado0843-03092BalboaAnconRepublic of Panama Department of Plant Biology and Pathology Rutgers UniversityNew BrunswickNJ 08901USA

Species of Ophiognomonia are leaf-inhabiting endophytes,pathogens,and saprobes that infect plants in the families Betulaceae,Fagaceae,Juglandaceae,Lauraceae,malvaceae,Platanaceae,Rosaceae,Salicaceae,and *** on extensive collecting,this speciesrich genus is now known to have a world wide distribution in primarily temperate areas,although some species are known from the *** of DNA sequences from three markers including guanine nucleotide-binding protein subunit beta-like protein(mS204),translation elongation factor 1α(tef-1α),and the ITS region including ITS1,5.8 S rDNA and ITS2 regions(ITS)were used to define phylogenetic species in *** plant association correlated with these ***-five new species of Ophiognomonia and two new combinations are proposed with descriptions and *** addition,descriptions and illustrations are provided for 12 other species of Ophiognomonia.A key is provided to the 45 currently accepted species of *** disposition of additional names in Ophiognomonia is also discussed.

关键词： Birch foliar pathogen Butternut canker GCPSR Genealogical sorting index Host associations mS204 multilocus phylogeny Walnut anthracnose and leaf blotch

Double-up for single-ion masses

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Nuclear Science and Techniques 2023年第7期34卷 159-161页

作者： Philip m.walker Department of Physics University of SurreyGuildford GU27XHUK

A cunning addition for the determination of nuclear masses provides world-leading sensitivity for accurate *** is already opening up new physics and *** may sound simple to weigh an atomic nucleus,but there is more to it than you might think,especially when the nucleus is very *** out the properties of such fleeting nuclei,perhaps surviving for only a few milliseconds,can solve long-standing science ***-lived nuclei are key to our understanding not only of how neutrons and protons bind together in nuclei,but also of the way that explosive events in the cosmos tell us about the life cycle of stars.

关键词： addition unstable stars

Implementation of Gas Control Algorithm in EASTPCS

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Plasma Science and Technology 2009年第2期11卷 231-235页

作者：袁旗平肖炳甲 m.walker 王华忠 Institute of Plasma Physics Chinese Academy of Sciences General Atomics DIII-D National Fusion Facility

In this paper, gas control on EAST in open and closed loop is discussed and its implementation into EASTPCS （plasma control system for the experimental advanced supercon- ducting tokamak） is introduced. Using a model to describe the plasma density response to the gas puff command, a gas simulation server （simserver） using mATLAB simulink tools and real time workshop was built up. Proper operation of the gas control algorithm was verified using this simserver. The simulation results suggested that the gas control can be applied in the next EAST campaign.

关键词： EASTPCS simserver gas control simulink model socket communication

Network science meets algebraic topology

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National Science Review 2019年第6期6卷 1064-1065页

作者： Lingqing Shen David m.walker michael Small Department of mathematics Nanjing University Department of mathematics & Statistics University of Western Australia mineral Resources Commonwealth Scientific and Industrial Research Organisation

Network science is largely consumed with the study of graphs with heterogeneous degree: typically large graphs with no strong topological symmetry. Network science borrows approaches from statistical physics to understand this heterogeneous structure, in a manner quite distinct from the rich symmetry of the graphs that are studied by algebraic graph theorists. Shi et al. [1] move toward

关键词： Network science meets algebraic topology

Observation of Zitterbewegung in photonic microcavities

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Light(Science & Applications) 2023年第6期12卷 1084-1090页

作者： Seth Lovett Paul m.walker Alexey Osipov Alexey Yulin Pooja Uday Naik Charles E.Whittaker Ivan A.Shelykh maurice S.Skolnick Dmitry N.Krizhanovskii Department of Physics and Astronomy University of SheffieldS37RH SheffieldUK Department of Physics and Technology ITMO UniversitySt.Petersburg 197101Russia Science Institute University of IcelandDunhagi 3IS-107 ReykjavikIceland

We present and experimentally study the effects of the photonic spin–orbit coupling on the real space propagation of polariton wavepackets in planar semiconductor microcavities and polaritonic analogues of *** particular,we demonstrate the appearance of an analogue Zitterbewegung effect,a term which translates as‘trembling motion’in English,which was originally proposed for relativistic Dirac electrons and consisted of the oscillations of the centre of mass of a wavepacket in the direction perpendicular to its *** a planar microcavity,we observe regular Zitterbewegung oscillations whose amplitude and period depend on the wavevector of the *** then extend these results to a honeycomb lattice of coupled microcavity *** to the planar cavity,such lattices are inherently more tuneable and versatile,allowing simulation of the Hamiltonians of a wide range of important physical *** observe an oscillation pattern related to the presence of the spin-split Dirac cones in the *** both cases,the experimentally observed oscillations are in good agreement with theoretical modelling and independently measured bandstructure parameters,providing strong evidence for the observation of Zitterbewegung.

关键词： planar versatile analogues

Spatiotemporal continuum generation in polariton waveguides

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Light(Science & Applications) 2019年第1期8卷 1117-1127页

作者： Paul m.walker Charles E.Whittaker Dmitry V.Skryabin Emiliano Cancellieri Ben Royall maksym Sich Ian Farrer David A.Ritchie maurice S.Skolnick Dmitry N.Krizhanovskii Department of Physics and Astronomy University of SheffieldSheffield S37RHUK Department of Physics University of BathBath BA27AYUK ITmO University Kronverksky Avenue 49St.Petersburg 197101Russia Department of Physics Lancaster UniversityLancaster LA14YBUK Department of Electronic and Electrical Engineering University of SheffieldSheffield S37HQUK Cavendish Laboratory University of CambridgeCambridge CB30HEUK

We demonstrate the generation of a spatiotemporal optical continuum in a highly nonlinear exciton–polariton waveguide using extremely low excitation powers(2-ps,100-W peak power pulses)and a submillimeter device suitable for integrated optics *** observe contributions from several mechanisms over a range of powers and demonstrate that the strong light–matter coupling significantly modifies the physics involved in all of *** experimental data are well understood in combination with theoretical *** results are applicable to a wide range of systems with linear coupling between nonlinear oscillators and particularly to emerging polariton devices that incorporate materials,such as gallium nitride and transition metal dichalcogenide monolayers that exhibit large light–matter coupling at room *** open the door to low-power experimental studies of spatiotemporal nonlinear optics in submillimeter waveguide devices.

关键词： millimeter waveguide optics

Realising the Potential of Genomics for m. tuberculosis: A Silver Lining to the Pandemic?

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China CDC weekly 2022年第20期4卷 437-439页

作者： Timothy m.walker Derrick W Crook Oxford University Clinical Research Unit Ho Chi Minh CityVietnam Nuffield Department of medicine University of Oxford OxfordUK

The impact of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic on tuberculosis has been ***,there were 1.4 million fewer patients receiving tuberculosis treatment in 2020,representing not a fall in the global case load but a failure to serve millions of patients with the disease(1–2).morbidity,mortality,and onward transmission are inevitable outcomes of such failure,setting the world back a decade of progress.

关键词： tuberculosis mortality acute

Expression of a constitutively active prolactin receptor causes histonetrimethylation of the p53 gene in breast cancer

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Chinese medical Journal 2014年第6期127卷 1077-1083页

作者： Tan Dunyong Tang Peizhi Huang Jianjun Zhang Jie Zhou Weihua Ameae m.walker College of medicine/Institute of medical Sciences/Affiliated Hospital Jishou University Jishou Hunan 416000 China Division of Biomedical Sciences University of Califomia RiversideRiverside CA 92521 USA

Background Prolactin(PRL) is a pituitary polypeptide hormone characterized by multiple biological actions including stimulation of growth in the prostate and formation of secretory alveoli and stimulation of milk protein gene expression in the mammary gland. PRL exerts its effect by dimerizing its receptor(PRLR) on the plasma membrane and regulating gene expression through the JAK-Stat signal pathway. We have previously described a natural variant of the PRLR in which the S2 subdomain of the extracellular domain is missing(Delta S2). Delta S2 PRLRs are dimerized in the absence of PRL and have constitutive activity in the promotion of breast cancer cell growth. Enhancer of zeste homolog 2(EZH2), as one of the histone-modifying enzymes, is a key factor regulating gene expression by epigenetic modification. We hypothesized that these constitutive activated Delta S2 PRLRs played a pathogenic role in breast cancer in part through alterations in the expression of EZH2 and the trimethylation of histone 3 on lysine 27(H3K27me3). methods In order to verify the clinical significance and to establish the link between Delta S2 PRLR expression and epigenetic change, EZH2, H3K27me3, and Delta S2 PRLR were detected in both normal and cancerous human breast tissues. Also, overexpression of Delta S2 PRLR in breast epithelial cells was achieved by infection with adenovirus carrying the cDNA. Western blotting and chromatin immunoprecipitation(ChIP assay) and acid histone extraction were applied to detect the expression of EZH2 and the trimethylation of histone 3, *** In breast tissue, higher EZH2 expression and higher H3K27me3 were found associated with higher Delta S2 expression in breast cancer samples. In breast epithelial cells, overexpression of Delta S2 PRLR increased EZH2 methyltransferase mRNA and protein, induced EZH2 methyltransferase recruitment to chromatin, increased the trimethylation of H3K27me3, and decreased the expression of p53 *** Delt

关键词： delta S2 prolactin receptor breast cancer enhancer of zeste homolog 2

创新行为如何影响政府绩效:以领导干部任前公示为例的研究探索

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兰州大学学报（社会科学版） 2006年第5期34卷 33-40页

作者：吴建南杨宇谦 Richard m.walker 西安交通大学公共政策与管理学陕西西安710061 Cardiff University UK Wales CF10 3XQ

在以往关注不同类型创新行为对组织绩效影响的研究中,组织氛围与沟通、人力资源与管理和行政成本是三类较为常见的影响因素,但三者尚未综合形成统一的框架。本研究选取了领导干部任前公示这一以人力资源管理为内容的创新行为,构建了三... 详细信息

在以往关注不同类型创新行为对组织绩效影响的研究中,组织氛围与沟通、人力资源与管理和行政成本是三类较为常见的影响因素,但三者尚未综合形成统一的框架。本研究选取了领导干部任前公示这一以人力资源管理为内容的创新行为,构建了三因素影响组织绩效的过程假设。通过分析问卷调查数据,发现三因素之间存在显著的相关性,且若按照组织边界划分绩效内容,三因素均与组织的内部成长建设绩效显著相关,而同组织外部绩效水平相关程度较弱。依此认为,创新行为影响绩效是一个由人、财、物三因素互动,并依据创新本身特点内容有所侧重的过程。

关键词：创新行为政府绩效干部任前公示

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity