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Blast disruption using 3D grids/perforated plates for vehicle protection

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Defence Technology（防务技术） 2023年第7期25卷 60-68页

作者： Therese Schunck dominique Eckenfels Laurent Sinniger French-German Research Institute of Saint-Louis ISL5 Rue Du General Cassagnou68300Saint-LouisFrance

In this work, blast disruption and mitigation using 3D grids/perforated plates were tested for underbelly and side protection of vehicles. Two vehicle simulants were used: a small-scale one for side vehicle protection assessment and a true-to-scale simulant for underbelly protection testing. The deformation of target plates was assessed. These were either unprotected or protected by three different types of disruptors. The first disruptor was made of a sandwich structure of two perforated plates filled with a thin aluminum structure allowing the air to pass through. The two other disruptors were made of pieces of cast metallic foam. Two different kinds of foams were used: one with large cells and the second one with small cells. Beforehand, the mitigation efficiency of the disruptors was evaluated using an explosivedriven shock tube(EDST). The experiments showed that blast disruption/mitigation by 3D grid/perforated plate structures was not suitable for vehicle side protection. However, 3D grids/perforated structures proved to be relatively effective for underbelly protection compared to an equivalent mass of steel.

关键词： Blast Mitigation Perforated plates 3D grids Vehicle protection

Runnel development on granitic boulders on the foothills of Mount Kinabalu(Pinosuk Gravel Formation,Sabah,N Borneo)

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Journal of Mountain Science 2016年第1期13卷 46-58页

作者： dominique DODGE-WAN Ramasamy NAGARAJAN Department of Applied Geology Curtin University SarawakCDT25098009 Min.SarawakMalaysia

Runnels are characteristic erosional features on karstified soluble rocks and can occasionally develop on less soluble rocks(*** and granites) but are poorly reported in *** research summarizes boulder distribution,size,petrology and runnel morphology in a Pleistocene post-glacial mudflow on Mount *** goal is to investigate the runnel formation on *** of boulders by cyanobacteria,mosses,lichens and higher plants is observed and related to rock surface meso-scale and micro-scale *** coarse porphyritic texture of the granite contributes to the fragmentation and mechanical weathering of large K-feldspar crystals in the *** damp runnel micro-environment is preferentially covered with mosses further enhancing weathering and *** runnels deepen,the remnant protruding fins of rock weaken and may break *** runnels are subaerial pseudokarst features,not the result of dissolution.

关键词： Mount rock dissolution granite break glacial weathering erosion fragmentation shallow

New insights on the molecular mechanisms of collateral sprouting after peripheral nerve injury

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Neural Regeneration Research 2021年第9期16卷 1760-1761页

作者： dominique Lemaitre Felipe A.Court Universidad del Desarrollo Facultad de MedicinaCentro de Fisiología Celular e IntegrativaSantiagoChile Center for Integrative Biology Faculty of SciencesUniversidad MayorSantiagoChile Geroscience Center for Brain Health and Metabolism(GERO) SantiagoChile The Buck Institute for Research on Aging NovatoCAUSA

Axonal regeneration after injuries to the nervous system has been extensively studied due to its implication in motor and sensory functional recovery. Distinct types of regeneration has been identified, such as canonical axonal regeneration, defined as the growth of axons from the transected axonal stump to reinnervate the original target, or regenerative sprouting, in which the growth occurs from a region of the damaged axon either close or far from the injury site(Tuszynski and Steward, 2012).

关键词： injuries injury collateral

Immune responses to Helicobacter pylori infection

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World Journal of Gastroenterology 2014年第19期20卷 5583-5593页

作者： Mati Moyat dominique Velin Service of Gastroenterology and Hepatology Department of MedicineLausanne University HospitalCH-1011 LausanneSwitzerland

Helicobacter pylori (H. pylori) infection is one of the most common infections in human beings worldwide. H. pylori express lipopolysaccharides and flagellin that do not activate efficiently Toll-like receptors and express dedicated effectors, such as γ-glutamyl transpeptidase, vacuolating cytotoxin (vacA), arginase, that actively induce tolerogenic signals. In this perspective, H. pylori can be considered as a commensal bacteria belonging to the stomach microbiota. However, when present in the stomach, H. pylori reduce the overall diversity of the gastric microbiota and promote gastric inflammation by inducing Nod1-dependent pro-inflammatory program and by activating neutrophils through the production of a neutrophil activating protein. The maintenance of a chronic inflammation in the gastric mucosa and the direct action of virulence factors (vacA and cytotoxin-associated gene A) confer pro-carcinogenic activities to H. pylori. Hence, H. pylori cannot be considered as symbiotic bacteria but rather as part of the pathobiont. The development of a H. pylori vaccine will bring health benefits for individuals infected with antibiotic resistant H. pylori strains and population of underdeveloped countries.

关键词： Helicobacter pylori Vaccine Immune response Peptic ulcer Gastric cancer

Effect of polymer and fiber additives on pressure drop in a rectangular channel

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Journal of Hydrodynamics 2017年第5期29卷 871-878页

作者： Amir Eshghinejadfard Kashyapa Sharma dominique Thévenin Laboratory of Fluid Dynamics and Technical Flows University of Magdeburg"Otto von Guericke"Universitatsplatz 239106 MagdeburgGermany

The influence of minute amounts of additives on pressure drop is an interesting fundamental phenomenon, potentially with important practical applications. Change of the pressure drop in a quasi-two-dimensional channel flow using various additives is experimentally investigated. Tests were conducted for a wide range of concentrations（100 ppm-500 ppm） and Reynolds numbers（16 000-36 000） with two polymers and four rigid fibers used as additive. Maximum drag reduction of 22% was observed for xanthan gum. However, xanthan gum loses its drag-reducing property rapidly. It was also seen that drag reduction percentage of xanthan gum remains almost constant for different Reynolds numbers. Guar flour demonstrated good drag reduction property at high Reynolds numbers. Drag reduction of 17.5% at Re= 33 200 using 300 ppm solution was observed. However, at low Reynolds numbers guar flour will cause an increase in pressure drop. Fiber fillers（aspect ratio=21） have been tested as well. In contrast to polymers, they increased the drag for the range of examined concentrations and Reynolds numbers. Polyacrylonitrile fiber with three different aspect ratios（106, 200, 400） was also used, which showed an increase in pressure drop at low aspect ratios. Polyacrylonitrile fibers of larger lengths（6 mm） demonstrated minor drag-reducing effects（up to 3%）.

关键词： Pressure drop polymer fiber channel flow

Cost implications of increased solar penetration and time-of-use rate interactions

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Clean Energy 2020年第3期4卷 247-269页

作者： dominique Bain Tom Acker School of Earth Sciences and Environmental Sustainability Northern Arizona UniversityFlagstaffAZ 86011 Mechanical Engineering Northern Arizona UniversityFlagstaffAZ 86011

Electricity-grid operators are facing new challenges in matching load and generation due to increased solar generation and peak-load *** paper demonstrates that time-of-use(TOU)rates are an effective method to address these *** rates use price differences to incentivize conserving electricity during peak hours and encouraging use during off-peak *** strategy is being used across the USA,including in Arizona,California and *** analysis used the production-cost model PLEXOS with an hourly resolution to explore how production costs,locational marginal prices and dispatch stacks(type of generation used to meet load)change due to changes in load shapes prompted by TOU rates and with additional solar *** modelling focused on implementing TOU rates at three different adoption(response)levels with and without additional solar generation in the Arizona balancing areas within a PLEXOS *** most cases analysed,implementing TOU rates in Arizona reduced reserve shortages in the Western Interconnect and,in some cases,very *** result is representative of the interactions that happen interconnection-wide,demonstrating the advantage of modelling the entire *** costs were decreased by the additional solar generation and the load change from TOU rates,and high response levels reduced the production costs the most for high-solar-generation *** change from TOU rates decreased locational marginal prices for a typical summer day but had inconsistent results on a high-load *** solar generation decreased the usage of combustion turbines,combined cycles and coal-fired generation.

关键词： energy system and policy production-cost model PLEXOS time-of-use rates solar energy locational marginal price

Going straight for the gut:gut-brain axis pathology and treatment of Parkinson's disease

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Neural Regeneration Research 2024年第10期19卷 2111-2112页

作者： dominique Ebedes Cesar V.Borlongan University of South Florida Morsani College of Medicine TampaFLUSA Center of Excellence for Aging and Brain Repair Department of Neurosurgery and Brain RepairUniversity of South Florida Morsani College of MedicineTampaFLUSA

This perspective focuses on the recent literature regarding the role of the gut-brain axis(GBA) in fecal microbiota transplantation(FMT) and stem cell therapy(SCT) in Parkinson's disease(PD).PD is the second most common neurodegenerative disease in the United States,yet therapies remain *** research suggests that the GBA may play a role in the pathogenesis of *** FMT as well as SCT offer promising new avenues for PD *** bing the interactions between FMT and SCT with the GBA may reveal novel therapeutics for PD.

关键词： straight pathology pathogenesis

Interest of molecular functionalization for electrochemical storage

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Nano Research 2017年第12期10卷 4175-4200页

作者： Bihag Anothumakkool dominique Guyomard Joel Gaubicher Lenaic Madec Institut des Materiaux Jean Rouxel (IMN) Universite de Nantes CNRS 2 rue de la Houssiniere BP32229 44322 Nantes Cedex 3 France IPREM-ECP CNRS UMR 5254 Universite de Pau Helioparc Pau Pyrenees 2 av. PierreAngot 64053 Pau Cedex 9 France Reseau sur le Stockage Electrochimique de I'Energie (RS2E) CNRS FR3459 33 Rue Saint Leu 80039 Amiens Cedex France

Despite great interests in electrochemical energy storage systems for numerous applications, considerable challenges remain to be overcome. Among the various approaches to improving the stability, safety, performance, and cost of these systems, molecular functionalization has recently been proved an attractive method that allows the tuning of material surface reactivity while retaining the properties of the bulk material. For this purpose, the reduction of aryldiazonium salt, which is a versatile method, is considered suitable; it forms robust covalent bonds with the material surface, however, with the formation of multilayer structures and sp3 defects （for carbon substrate） that can be detrimental to the electronic conductivity. Alternatively, non-covalent molecular functionalization based on π-π interactions using aromatic ring units has been proposed. In this review, the various advances in molecular functionalization concerning the current limitations in lithium-ion batteries and electrochemical capacitors are discussed. According to the targeted applications and required properties, both covalent and non-covalent functionalizafion methods have proved to be very efficient and versatile. Fundamental aspects to achieve a better understanding of the funcfionalization reactions as well as molecular layer properties and their effects on the electrochemical performance are also discussed. Finally, perspectives are proposed for future implementation of molecular functionalization in the field of electrochemical storage.

关键词： electrochemical storage molecularfunctionalization covalent diazoniumchemistry non-covalent π-π interactions

Variceal bleeding in cirrhotic patients

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Gastroenterology Report 2017年第3期5卷 185-192,I0001页

作者： Maxime Mallet Marika Rudler dominique Thabut Unitede Soins Intensifs d’Hepatologie Service d’Hepato-GastroenterologieGroupe Hospitalier Pitie-Salpetriere Charles FoixAssistance Publique-Hopitaux de ParisParisFrance

Variceal bleeding is one of the major causes of death in cirrhotic *** management during the acute phase and the secondary prophylaxis is well *** recommendations(2015 Baveno VI expert consensus)are available and should be followed for an optimal management,which must be performed as an emergency in a liver or general intensive-care *** is based on the early administration of a vasoactive drug(before endoscopy),an antibiotic prophylaxis and a restrictive transfusion strategy(hemoglobin target of 7 g/dL).The endoscopic treatment is based on band *** should be *** the most severe patients(Child Pugh C or B with active bleeding during initial endoscopy),transjugular intrahepatic portosystemic shunt(TIPS)should be performed within 72 hours after admission to minimize the risk of *** prophylaxis is based on the association of non-selective beta-blockers(NSBBs)and repeated band *** should be considered when bleeding reoccurs in spite of a well-conducted secondary prophylaxis or when NSBBs are poorly *** should also be considered when bleeding is *** transplantation should be discussed when bleeding is not controlled after TIPS insertion and in all cases when liver function is deteriorated.

关键词： variceal bleeding cirrhosis endoscopic treatment non-selective beta-blockers transjugular intrahepatic portosystemic shunt liver transplantation