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Effects of two types of exercise training on psychological well-being,sleep,quality of life and physical fitness in patients with high-grade glioma(WHO III and IV):study protocol for a randomized controlled trial

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Cancer Communications 2019年第1期39卷 420-429页

作者： dominik cordier Markus Gerber Serge Brand Department of Neurosurgery University Hospital Basel4031 BaselSwit-zerland Division of Sport and Psychosocial Health Department of SportExercise and HealthUniversity of Basel4052 BaselSwitzerland Center for Affective Stress and Sleep Disorders(ZASS)Psychiatric Clinics(UPK)University Basel4002 BaselSwitzerland Department of Psychiatry Substance Abuse Prevention Research CenterHealth InstituteKermanshah University of Medical Sciences(KUMS)Kermanshah ***Iran Sleep Disorders Research Center Department of PsychiatryKermanshah University of Medical Sciences(KUMS)Kermanshah ***Iran

Background:There is existing evidence on whether and to what degree regular exercise training improves the quality of life(QoL)among cancer ***,in regards to patients with high-grade glioma(HGG;WHO grade III and IV),no conclusive study has been performed so *** present trial aims to fill this gap by examining whether psychological well-being,sleep,QoL and physical fitness might be improved with two different types of exercise,as compared to an active control *** control condition represent individuals participating at regular meetings to talk about their current life situation,though,the meetings were not intended as that of the psychotherapy *** meetings are of the same frequency,duration,and intensity as the exercise ***:A total of 45 patients with HGG after undergoing neurosurgery and adjuvant radiotherapy,chemotherapy,or chemoradiotherapy will be consecutively and randomly assigned to(a)an endurance training,(b)a resistance training or(c)to an active control *** intervention will last for 6 consecutive weeks,consisting of 2 weekly sessions(30-45 min per session).Measurements would take place at three time points,namely at the beginning of the study(baseline),3 weeks after the beginning of the study,and 6 weeks after the beginning of the *** last measurement also represents the end of the *** exercise performance will be assessed objectively with a 6-min walking test,and a handgrip test will be used to assess the upper body ***,participants will complete a battery of questionnaires covering sociodemographic information,QoL,sleep quality and sleep patterns,coping with stress,state-and trait-anxiety,depression,and *** parallel,experts will use the Hamilton Depres-sion Rating Scale to determine and rate participants’symptoms of ***:The present study will be the first to investigate and compare the impact of two different exercise modalities,na

关键词： Brain Tumor Glioma Exercise Training Sleep Control condition Quality of life Anxiety Perceived stress

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