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Kawasaki Disease in a Togolese Child

Open Journal of Pediatrics 2022年第2期12卷 293-296页

作者： Koffi Mawuse Guedenon doguénsaga borgatia attah Djatougbe Ayaovi Elie Akolly Mawouto Fiawoo Kokou Placide Agbo-Kpati Adama Dodji Gbadoe Department of Pediatrics CHU Sylvanus Olympio University of Lomé Lomé Togo Department of Cardiology CHR Sokodé University of Kara Kara Togo Department of Pediatrics GHEF Site de Marne La Vallée Jossigny France

Introduction: Kawasaki disease (KD) is a severe febrile vasculitis that affects children under 5 years of age. The severity of KD is related to coronary involvement. Few cases have been reported in sub-Saharan Africa. Objective: We present a clinical observation of a Togolese infant to illustrate the typical clinical picture that every pediatrician should know. Observation: The patient was a 20-month-old infant from Togo who presented with conjunctivitis, cheilitis, stomatitis, and pharyngitis in a febrile setting. There was a satellite sub-maxillary adenopathy. There was a persistent biological inflammatory syndrome with thrombocytosis and a doppler ultrasound confirmed the diagnosis of a coronary aneurysm. Treatment was based on corticosteroid therapy and acetylsalicylic acid with success. Conclusion: KD involves cardiac complications that require rigorous and sometimes long-term monitoring to prevent death.

关键词： Kawasaki Disease Lympho-Cutaneous-Mucosal Syndrome Vascularity Coronary Aneurysm

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Hypertrophic Cardiomyopathies at the Sylvanus Olympio Teaching Hospital of Lome: Epidemiological, Diagnostic, Therapeutic and Evolutive Aspects

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World Journal of Cardiovascular Diseases 2022年第11期12卷 481-489页

作者： Baragou Soodougoua Afassinou Yaovi Mignazonzon Hourobia Watabisse Atta borgatia Oloude Nansirine Pessinaba Souleymane Damorou Findibe University of Lome Lome Togo University of Kara Kara Togo

Background: Hypertrophic cardiomyopathy (HCM) is a form of cardiomyopathy that may involve several *** aim of our study is to describe the epidemiological, diagnostic, therapeutic and short-term prognostic aspects of this form of cardiomyopathy at the Sylvanus Olympio Teaching Hospital of Lome. Materials and Methods: This was a cross-sectional study that was carried out over a four-year period from January 1, 2016 to December 31, 2019. We included in this study, patients admitted to the Cardiology Department of the Sylvanus Olympio Teaching Hospital of Lome, in whom the diagnosis of hypertrophic cardiomyopathy was retained at echocardiography in the absence of any other cause that could explain the significant hypertrophy of the walls. Results: The prevalence of hypertrophic cardiomyopathies in our study was 0.31%. The mean age of patients was 51.35 ± 15.28 years with a male predominance (sex ratio M/F of 1.22). The majority of patients (60%) were between 45 and 74 years old. The clinical presentation was dominated by congestive heart failure in 15 patients (75%). Half of the patients (50%) had type III hypertrophic cardiomyopathy according to Maron’s classification. Seven patients (35%) had obstructive HCM and the mean thickness of the interventricular septum in diastole was 15.88. Left ventricular systolic function was impaired in 40% of patients. No patient was able to do a genetic test. The combination of beta-blocker (95%), an inhibitor of the renin- angiotensin-aldosterone system (90%) and furosemide (85%) constituted the essential part of the treatment combined with Lifestyle changes. No patients have benefited from implantable cardioverter defibrillators. The yearly mortality rate at the end of our study was 70%. Conclusion: Hypertrophic cardiomyopathy remains a relatively rare pathology. It is often a late diagnosis in the context of heart failure with limited therapeutic means, explaining its heavy morbidity and mortality.

关键词： Hypertrophic Cardiomyopathy Echocardiography Togo

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Mortality in Cardiology in Sub-Saharan Africa: Case of the Cardiology Department of the Teaching Hospital Sylvanus Olympio of Lome

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World Journal of Cardiovascular Diseases 2023年第8期13卷 477-492页

作者： Afassinou Yaovi Mignazonzon Dola Kossi Edem Pessinaba Soulemane Atta borgatia Pio Machihude Baragou Soodougoua Damorou Findibe Cardiology Department Sylvanus Olympio Teaching Hospital of Lome Lome Togo Cardiology Department Teaching Hospital Campus of Lome Lome Togo Medical Department Sokode Regional Hospital Center Sokode Togo Cardiology Department Kara Teaching Hospital Kara Togo

Background: Cardiovascular disease is the leading cause of death worldwide. The specificities of cardiology mortality in Togo are not well known. The objective of this study was to determine the profile of deaths in the cardiology department of the Sylvanus Olympio Teaching Hospital (CHU SO) in Lome. Materials and Methods: This was a cross-sectional study conducted over a period of 06 years, from January 1, 2015 to December 31, 2021, in the cardiology department of the Sylvanus Olympio Teaching Hospital in Lome. In this study, we included all medical records of patients who died in hospital in the cardiology department during the study period. Results: During the study period, 2762 patients were hospitalized in the cardiology unit at CHU SO. We recorded 112 deaths meeting our criteria, for an intrahospital mortality rate of 4.19%. The average age of patients was 53.79 ± 18.27 years. Hypertension was present in 47.3%. Sickness insurance coverage was not available for 94.64% of those who died. The major cardiovascular diseases observed were myocardium in 43.75% whose dilated cardiomyopathy accounted for 71.42%;and rhythmic lesions in 34.82%. Biological infectious syndrome (56.25%), renal failure (48.21%), anemia (47.27%), lung infection (32.14%), hyponatremia (33.04%) were the main comorbidities observed. Among the circumstances of death, sudden death was found in 32.14%, cardiogenic shock in 20.54% and septic shock in 13.39%. Conclusion: The profile of deaths in the cardiology department of the CHU SO reveals that myocardial injuries are more present with circumstances of death dominated by sudden death.

关键词： Mortality Rate Cardiology CHU Sylvanus Olympio

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Brugada Syndrome Type 1 Electrocardiogram Pattern Induced by Fever in a Black African: A Case Report

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World Journal of Cardiovascular Diseases 2020年第8期10卷 558-562页

作者： Soulemane Pessinaba Ekpé Togbossi Wiyaou Kaziga Baete Koudéma Pizeriwé Dossim Komlavi Yayehd Mohamed Kpélafia Nkenon Watani N’Da borgatia Atta Tchaa Tchérou Yaovi Afassinou Machihude Pio Soodougoua Baragou Adama Kane Findibe Damorou Cardiology Department Campus Teaching Hospital Lome Togo Cardiology Department Kara Teaching Hospital Kara Togo Cardiology Department Sylvanus Olympio Teaching Hospital Lome Togo Cardiology Department Saint-Louis Hospital Saint-Louis Senegal

Brugada syndrome is a channelopathy that can be familial or sporadic. It is a major cause of sudden death in young people with no obvious heart structural abnormality. The electrocardiogram can be dynamic over time with sometimes normalization. Several pathophysiological conditions are known to induce the electrocardiographic expression of the syndrome. We report here the case of a 65-year-old hypertensive man, without syncope or family sudden death history who was hospitalized for shigella gastroenteritis. Electrocardiogram during fever showed an incomplete block and ST segment elevation with negative T waves in V1 and V2 suggested type 1 Brugada syndrome. Troponin was negative. Electrocardiogram after fever recovered an incomplete right block and normalization of the ST segment. Electrocardiogram should be performed in patients admitted to the emergency unit for infectious syndrome in our countries. This may reveal a number of patients with Brugada syndrome abnormalities.

关键词： Brugada Syndrome Electrocardiogram Fever

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