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Nanofibrous ε-polycaprolactone scaffolds containing Ag-doped magnetite nanoparticles: Physicochemical characterization and biological testing for wound dressing applications in vitro and in vivo

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Bioactive Materials 2021年第7期6卷 2070-2088页

作者： M.K.ahmed M.A.Zayed S.I.El-dek Mayssa Abdel Hady doaa H.El Sherbiny Vuk Uskokovic Faculty of Nanotechnology for Postgraduate studies Cairo UniversityEl-Sheikh Zayed 12588Egypt Department of Physics Faculty of ScienceSuez UniversitySuez 43518Egypt Chemistry Department Faculty of ScienceCairo University12613GizaEgypt Materials Science and Nanotechnology Department Faculty of Postgraduate Studies for Advanced SciencesBeni-Suef UniversityBeni SuefEgypt Pharmaceutical Technology Department National Research CentreDokiiGizaEgypt Advanced Materials and Nanobiotechnology Laboratory TardigradeNano LLCIrvineCA92604USA Department of Biochemistry Faculty of DentistryModern University for Technology and InformationMokattamCairoEgypt

Skin wounds can lead to numerous complications with dangerous health *** this work,magnetite nanoparticles were doped with different concentrations of antimicrobial silver(Ag)ions and incorporated into the electrospun nanofibrous ε-polycaprolactone(PCL)*** and scaffolds with various Ag contents were characterized using a range of physicochemical *** entered magnetite as cations and preferentially positioned at tetrahedral sites,introducing lattice distortions and topographic *** of the structure due to accommodation of Ag expanded the lattice in the bulk and contracted it on the surface,where broadened distribution of Fe-O coordinations was *** spin canting and diminishing the double exchange interaction through altered distribution of ferric and ferrous ions,Ag softened the magnetism of *** making the nanoparticle structure more defective,Ag modified the interface with the polymer and promoted the protrusion of the nanoparticles from the surface of the polymeric nanofibers,thus increasing their roughness and hydrophilicity,with positive repercussions on cell adhesion and *** the viability of human melanocytes and the antibacterial activity against *** and *** increased with the concentration of Ag in the magnetite phase of the *** wound healing rate in rats also increased in direct proportion with the concentration of Ag in the magnetite phase,and no abnormalities in the dermal and epidermal tissues were visible on day 10 in the treatment *** results imply an excellent potential of these composite nanofibrous scaffolds for use as wound dressings and in other reconstructive skin therapies.

关键词： Tissue engineering Wound healing Skin Magnetic nanoparticles Nanofiber

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Characterization and Impact of Cattle Manure Particle Size on Physical Properties of Sandy Soils

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Journal of Geoscience and Environment Protection 2019年第8期7卷 180-194页

作者： doaa ahmed El-Nagar Ramadan Abd Alaaty Mohamed Soil Improvement Department Soil Water and Environment Institute (Agricultural Research Center) Egypt Vegetable Crops Department Horticulture Research Institute (Agricultural Research Center) Egypt

Sandy soils have poor physical properties, which cause them to drain quickly and not hold water well;however, with the addition of cattle manure, sandy soil can be improved. Therefore, experiments were conducted to investigate the characterization and impact of different particle sizes of cattle manure (CMS) on improving some physical properties of sandy soil and thus the yield of lettuce. Cattle manure was ground to powder and was sieved with three different Particle sizes 4.76-2 (CMS1), 2-0.8 (CMS2), 0.8-0.4 (CMS3) mm. Some physical properties were measured for different Particle sizes of manure. A batch of sorption experiments was carried out to study the role of different Particle sizes of manure on adsorption of N, P and K from aqueous solution. Two experiments were carried out on sandy soil (pots and field) to study the impact of adding CMS (5 ton/fed) to enhance some physical properties of sandy soil. The results indicated that the physical properties of cattle manure changed based on particle size fractionation, where Bulk density and saturated water holding capacity increased as particle size decreased, while porosity reduced as particle size decreased. The results of the sorption parameters of N, P and K on different particle sizes of manure indicated that maximum sorption occurred on CMS 3 for both P and K according to Langmuir and Freundlich sorption models. Two experiments showed that CMS had affected significantly the total porosity (TP), bulk density (Bd), slowly drainable pores (SDP), water holding pores and (WHP) available water (AW) in comparison to control. The CMS had a slight effect on Quickly-drainable pores (QDP) and fine capillary pores (FCP) as compared to the control in both experiments. Fresh weight, dry weight and number of leaf lettuce increased significantly with decreasing particle sizes of cattle manure as compared to control.

关键词： Cattle Manure Size Soil Properties Langmuir and Freundlich Sorption Models

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沸石催化甘蔗渣裂解制备多壁碳纳米管

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燃料化学学报 2021年第10期49卷 1421-1434页

作者： ABOUL-ENEIN Ateyya A AWADALLAH ahmed E EL-DESOUKI doaa S ABOUL-GHEIT Noha AK Process Development Division Egyptian Petroleum Research InstituteCairo 11727Egypt EPRI-Nanotechnology Center Egyptian Petroleum Research InstituteCairo 11727Egypt

通过催化热解农业废弃物甘蔗渣(SCB),采用两步工艺生产具有显著应用价值的碳纳米管(CNTs)。主要研究沸石催化剂(HZSM-5、HMOR和HY)、热解温度(450−700℃)和SCB/ZSM-5的比例(3−12)对SCB催化热解的影响,确定最佳工艺参数。随后,将第一步... 详细信息

通过催化热解农业废弃物甘蔗渣(SCB),采用两步工艺生产具有显著应用价值的碳纳米管(CNTs)。主要研究沸石催化剂(HZSM-5、HMOR和HY)、热解温度(450−700℃)和SCB/ZSM-5的比例(3−12)对SCB催化热解的影响,确定最佳工艺参数。随后,将第一步产生富含碳的热解产物用于第二步由Co-Mo/MgO催化生长CNTs。通过简单的两步工艺催化热解SCB生产CNTs。SCB的催化热解在半间歇式反应器(外径=4 cm,长度=90 cm)中进行,CNTs的生长在水平反应器(外径=2.5 cm,长度=100 cm)中进行。两个反应器通过玻璃管(直径0.6 cm,长度12 cm)连接并将热解产物从反应器I转移到反应器II。在半间歇式反应器中放入经过预处理的SCB和沸石催化剂,并以20℃/min加热到反应所需温度。随后,将0.5 g Co-Mo/MgO加入到水平反应器中作为CNTs的生长催化剂。在一个典型的实验中,将2 g沸石催化剂、24 g SCB放入半间歇式反应器,研究了不同种类沸石催化剂在500℃温度条件下对SCB热解的影响。接着,使用HZSM-5研究了不同温度(450−700℃)对SCB热解的影响。最后,研究了不同SCB/ZSM-5投料比例(SCB/ZSM-5=3、6、9、12)对SCB热解的影响。此外,水平反应器中的CNTs生长温度恒定为700℃。通过XRD、TPR和TPD进行催化剂表征。XRD谱图证实了催化剂存在MgO和Co_(3)O_(4),以及以小尺寸颗粒形式存在的CoMoO4和MgMoO4。使用XRD数据根据Scherrer方程计算45%Co-5%Mo/MgO催化剂的平均晶粒尺寸为25.8 nm。TPR分析表明,Co-Mo/MgO催化剂是由未反应的Co_(3)O_(4)以及混合氧化物组成。使用XRD数据,计算得到HZSM-5、HMOR和HY的平均晶粒尺寸分别为43、41和51 nm。NH3-TPD分析表明沸石催化剂存在大量的酸性位点。催化热解SCB结果表明,由HY和HZSM-5催化剂在500℃得到的挥发性产品(生物油和气体)的总收率值分别为34.4%和32.8%,而使用HMOR产生的这些挥发性产品的收率值最低(28.8%)。用HZSM-5催化热解SCB获得了最高的炭产量(23.1%)。然而,使用HMOR和HY热解催化剂产生的炭产量值较低,分别为15.8%和9.8%。使用TEM表征通过两步法生产的碳纳米管,并且测量了CNTs的外径。数据显示,用HZSM-5进行SCB热解产生了直径分布范围较宽的CNTs(10−56 nm),而用HMOR和HY热解催化剂则分别获得了直径较窄的CNTs(13−44 nm,12−28 nm)。拉曼光谱分析表明,使用HZSM-5作为SCB热解的催化剂可以生产最优的CNTs。研究了不同热解温度对CNTs产量的影响。结果显示,将热解温度从450℃提高到500℃,炭产率值从6.7%达到最佳值23.1%,接着增加温度至700℃,炭产量下降至16.7%。随后对不同温度下催化热解形成的炭产品进行TEM表征,结果显示,随着温度的升高炭产品中CNTs的比例下降,CNTs的直径范围变窄。拉曼光谱分析结果表明,在500和700℃形成的CNMs具有最少的缺陷。研究了投料比例对炭产品产量的影响,结果表明,SCB/ZSM-5的比例从3提高到12,生物油和气体的总产量从36.4%下降到32.8%,而生物炭的产量分别从63.6%增加到67.2%。根据催化剂的质量计算得到炭产量的最佳值是使用SCB/ZSM-5比例为6。使用TEM表征不同投料比例生产的炭产品,分析表征结果可得SCB/ZSM-5的比例为6,是形成具有良好质量的致密CNTs的最佳选择。并且不同投料比例的拉曼光谱显示,SCB/ZSM-5比例为6可以生产最优的CNTs。沸石类型(HZSM-5、HMOR和HY)、热解温度(450−700℃)和SCB/ZSM-5比例(3−12)影响CNTs和热解产物(气体、生物油和生物炭)的产量。实验结果表明,获得最高CNTs产量的条件为:热解温度为500℃、SCB/ZSM-5比例为6;获得最高生物油和气体总产量(40%)的条件为:热解温度为700℃、SCB/ZSM-5比例为12。TEM分析表明,使用HZSM-5催化剂在热解温度450℃只生成竹节状碳纳米管(BCNTs),而CNTs和碳纳米洋葱(CNO)是在较高温度热解温度(500−700℃)下产生的。使用SCB/ZSM-5的比例为6时,生成CNTs的直径分布范围最大(7−76 nm)。拉曼光谱分析表明,使用SCB/ZSM-5的比例为6时,形成的CNTs最优。该研究显示,在半间歇式反应器中催化热解SCB是生产CNTs的有效技术,通过对工艺和反应器的优化可以达到更好的效果。

关键词：碳纳米管 Co-Mo/MgO 热解甘蔗渣 ZSM-5沸石

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Role of Program-for-Results Financing System in Infrastructure Sector:Evidence from Egypt and Ethiopia

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Proceedings of Business and Economic Studies 2018年第3期1卷 1-16页

作者： ahmed M.Noureldin doaa M.Salman Abdou Housing Building National Research Center CairoEgypt Department of Economics October University for Modern Sciences and ArtsGizaEgypt

This study aims are two folds:First is to investigate the role of the World Bank funding through using a novel financing instrument called Program-for-Results(P for R)to strengthen the government programs and second is to assess the P for R programs adopted in countries focusing on the direct effects and the *** Bank currently has three integral financing options to offer client countries:Investment Project Financing supports specific projects and disburses against specific expenditures and transactions,Development Policy Lending supports policy and institutional reforms and provides general budget support,and P for R Financing supports government programs and disburses against *** for the P for R reflect on the new level because disbursements are directly linked to the achievement of measurable and verifiable *** well,the Disbursement-Linked Indicators(DLIs)are used to provide governments with incentives to achieve critical program milestones and enhance the performance of *** study structured based on descriptive and observed the behavior of two countries’government(Egypt and Ethiopia)for using P for R financing loan in a national *** the ground,the field of practices was the main indicator in this stage of the investigation,then one of the P for R programs was compared to observe the effectiveness of this kind of financing system in these two countries specifically in the infrastructure sector,and classifications of DLIs were the main parameter in this *** outcome and the existing literature are analyzed to develop a multibeneficial for country adopting P for R collaborative programs,as they should be applied to mitigate the same challenges and solve the institutional complications for the beneficial countries ***,enhance the profit generated from this kind of program targeting via sustainable management tools.

关键词： program for results foreign aid international financial institutions world bank resultsbasedaid disbursement-linked indicators

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Colorectal cancer in Arab world:A systematic review

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World Journal of Gastrointestinal Oncology 2021年第11期13卷 1791-1798页

作者： Nahed A Makhlouf Muhammad Abdel-Gawad Aya M Mahros Sameh A Lashen Mariam Zaghloul ahmed Eliwa Eman E Elshemy Zainab Ali-Eldin doaa Abdeltawab Fathiya El-Raey Dalia Omran Marwa Khalaf Nancy Fanous ahmed Shawkat Abdelmohsen ahmed Abu-Elfatth Mohamed Abdelghani Mahmoud Farouk Mohamed Abdelaziz Mohamed Alboraie Department of Tropical Medicine and Gastroenterology Faculty of MedicineAssiut UniversityAssiut 71515Egypt Department of Hepatology Gastroenterologyand Infectious DiseasesAl-Azhar UniversityAssiut 71631Egypt Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversityKafrelsheikh 33656Egypt Department of Internal Medicine Alexandria UniversityAlexandria 21521Egypt Department of Internal Medicine Al-Azhar UniversityCairo 11884Egypt Department of Hepatogastroenterology and Infectious Diseases Al-Azhar UniversityCairo 11651Egypt Department of Internal Medicine Ain Shams UniversityCairo 11646Egypt Department of Hepatogastroenterology and Infectious diseases Faculty of MedicineAl-Azhar UniversityDamietta 34511CairoEgypt Department of Endemic Medicine Cairo UniversityCairo 12613Egypt Department of Tropical Medicine and Gastroenterology Assiut Liver CenterAssiut 71511Egypt Department of Gastroenterology Hepatology and EndoscopyPolice Authority HospitalCairo 12654Egypt Department of Clinical Oncology and Nuclear Medicine Al-Azhar UniversityCairo 11824Egypt

BACKGROUND The incidence of colorectal cancer(CRC)is increasing among young individuals in the Arab world as well as in other regions of the *** To explore the incidence and prevalence of CRC in the Arab *** The PubMed,Scopus,Web of Science,EBSCO and Wiley databases were searched to retrieve relevant articles irrespective of the language or the publication *** search terms were("colon OR rectum OR sigmoid OR rectal OR colonic OR colorectal")AND("cancer OR malignancy OR malignant OR neoplasm")AND("Jordan"OR"United Arab Emirates"OR"Bahrain"OR"Tunisia"OR"Algeria"OR"Djibouti"OR"Saudi Arabia"OR"Sudan"OR"Syria"OR"Somalia"OR"Iraq"OR"Oman"OR"Palestine"OR"Qatar"OR"Comoros"OR"Kuwait"OR"Lebanon"OR"Libya"OR"Egypt"OR"Morocco"OR"Mauritania"OR"Yemen").Reviews,metaanalyses,and articles containing nonoriginal data were *** articles were screened,and relevant data were *** statistics were used for data *** Nine studies were *** of the studies provided information regarding the prevalence of *** prevalence of CRC was 0.72% in Saudi Arabia and 0.78% in the United Arab Emirate,while in Egypt,it ranged from 0.4% to 14%.Four studies showed information regarding the *** annual incidence rate of CRC in Qatar was 7.5/100000/*** Egypt,the crude incidence rate(CIR)in males was 3.1 for colon cancer and 1 for rectal cancer,while in females,it was 2.3 for colon cancer and 0.8 for rectal *** age-standardized rate for CRC incidence in 2003 was 36.90 for males,26.50 for females,and 30.49 for both sexes in Saudi *** 2016,the CIRs in Saudi Arabia were 3.6 and 2.1 in females for colon cancer and rectal cancer,respectively,while in males,it was 3.3 and 2.8 for colon cancer and rectal cancer,*** study in Egypt revealed that 25% of CRC cases occurred among individuals younger than 40 years *** There is a considerable prevalence of CRC in some Arab *** studies are n

关键词： Colorectal cancer Incidence Prevalence Arab world

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The Role of Circulating MicroRNAs as Markers of Disease Progression in Hepatitis C Virus Infected Egyptian Patients

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Advances in Microbiology 2016年第4期6卷 320-331页

作者： Reem Abdel Hamid Harfoush Marwa ahmed Meheissen Reham Abel Haleem Abo Elwafa doaa ahmed Elwazzan Medical Microbiology and Immunology Department Faculty of Medicine University of Alexandria Alexandria Egypt Clinical and Chemical Pathology Department Faculty of Medicine University of Alexandria Alexandria Egypt Tropical Medicine Department Faculty of Medicine University of Alexandria Alexandria Egypt

Background: The discovery of miRNAs circulating in the peripheral blood has opened new directions of research to identify new non-invasive markers for diagnosis of diseases. Aim: The aim of the study was to evaluate the expression levels of circulating plasma miRNAs (miRNA-21 & miRNA-122) in Egyptian patients with chronic uncomplicated and complicated HCV. Patients & Methods: This study was conducted on 60 Chronic HCV infected patients. Patients were divided into three groups (20 patients each): uncomplicated HCV, cirrhosis, and hepatocellular carcinoma (HCC). All patients were subjected to laboratory investigations including complete blood picture, liver function tests. Expression levels of miRNA-21 and -122 in plasma using RT-PCR were determined. Results: MiRNA-21 showed significant fold increase in chronic uncomplicated HCV while significant fold decrease in cirrhotic and HCC groups (P = 0.036). On the other hand, miRNA-122 showed significant fold elevation in both chronic uncomplicated and cirrhotic groups and significant fold decrease in HCC group (P = 0.005). ROC curve analysis for miRNA-122 yielded 68.4% sensitivity and 100% specificity for the differentiation of HCC patients from non-HCC at a cutoff 0.184. Neither miRNA-21 nor miRNA-122 was a successful predictor for HCC diagnosis. Conclusion: MiRNA-122 can be used as novel non-invasive biomarker for monitoring HCV related disease progression.

关键词： MicroRNA Hepatocellular Carcinoma Hepatitis C Virus

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Development of NIS Two-Temperature Humidity Generator

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Journal of Physical Science and Application 2014年第7期4卷 436-439页

作者： Mohamed Gamal ahmed Said Mazen doaa Abd El-Gelil National Institute for Standard Giza Egypt Physics Department Faculty of Science Zagazig University Sharkia Egypt

Abstract： This paper describes the development and characterization of a two-temperature （2-T）, constant pressure humidity generator It relies on the saturation of a stream of gas flowing over a water surface maintained at constant, well-known, temperature. It was built in order to improve the uncertainties of the dew-point temperature and humidity scales realization at the National Institute for Standard （NIS） in the dew-point range from -50 ℃ to ＋ 10 ℃. Several experiments were carried out in the above mentioned range in order to characterize the generator. Characterization comprised studies of its saturator efficiency, temperature stability and a comparison with a calibrated chilled-mirror hygrometer. The results of the efficiency tests showed good performance of the generator as described below. For uncertainty of measurements, a thorough analysis was also described representing estimations of contributions for all the sources that affecting measurements.

关键词： Dew-point hygrometer two-temperature generator uncertainty.

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Botulinum Toxin Type A Satisfaction in Different Neurological Disorders

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Neuroscience & Medicine 2022年第1期13卷 1-16页

作者： Jasem Yousef Al-Hashel doaa Youssry Soliman Ismail Ibrahim Ismail Samar Farouk ahmed Department of Neurology Ibn Sina Hospital Kuwait City Kuwait Department of Medicine Faculty of Medicine Health Sciences Centre Kuwait University Kuwait City Kuwait Department of Neurology Cairo University Cairo Egypt Department of Neuropsychiatry Faculty of Medicine Minia University Minia Egypt

Background: The botulinum toxin type A (BoNT-A) is used in a wide range of neurological diseases. We aimed to study the overall patients/caregivers’ satisfaction with BoNT-A treatment in different neurological conditions. Methods: Prospective study included patients who had received at least two BoNT-A treatment sessions. They were asked to rate overall treatment satisfaction at the peak of treatment effect on a 1 to 10 scale (1 = not at all satisfied;10 = fully satisfied). Subjects with a rating of 1to3 were classified as not at all satisfied, those with a rating of 4 to7 as somewhat satisfied, and those with a rating of 8 to10 as very satisfied. Treatment satisfaction questionnaire for medicine (TSQM) was assessed at the end of observational period. Quality of life QOL was assessed before BoNT-A treatment and at the last visit. Results: The study was conducted from first April 2014 to August 2021. 548 patients were identified with mean age 43.66 ± 14.50. Most of participants 389 (71%) were female. At the end of observational period, the mean satisfaction was 7.28 ± 1.78. There was a highly significant difference (P P P = 0.001). Conclusion: Satisfaction with BoNT-A therapy for different neurological disorders is overall good. The highest patient satisfaction was observed with primary focal HH, and the least satisfaction was observed in writer’s cramp. BoNT-A therapy improved QOL.

关键词： Botulinum Toxin Type A Satisfaction Headache Dystonia Movement Disorders Hyperhidrosis

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Solar Thermal Aquaculture System Controller Based on Artificial Neural Network

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Engineering（科研） 2011年第8期3卷 815-822页

作者： doaa M Atia Faten H Fahmy Ninet M ahmed Hassen T Dorrah 不详

Temperature is one of the most principle factors affects aquaculture system. The water temperature is very important parameter for shrimp growth. It can cause stress and mortality or superior environment for growth and reproduction. The required temperature for optimal growth is 34oC, if temperature increase up to 38oC it causes death of the shrimp, so it is important to control water temperature. Solar thermal water heating system is designed to supply an aquaculture pond with the required hot water in Mersa Matruh in Egypt as presented in this paper. This paper introduces a complete mathematical modeling and MATLAB SIMULINK model for the solar thermal aquaculture system. Moreover the paper presents the control of pond water temperature using artificial intelligence technique. Neural networks are massively parallel processors that have the ability to learn patterns through a training experience. Because of this feature, they are often well suited for modeling complex and non-linear processes such as those commonly found in the heating system. They have been used to solve complicated practical problems. The simulation results indicate that, the control unit success in keeping water temperature constant at the desired temperature by controlling the hot water flow rate.

关键词： Aquaculture Forced Circulation Hot Water System Artificial Neural Networks

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Decaying of Nitrogen Second Positive System by Addition of H<sub>2</sub>Gas in Air DB Discharge

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Journal of Modern Physics 2013年第2期4卷 160-167页

作者： doaa M. El-Zeer ahmed Samir Farouk Elakshar Abdo A. Garamoon Center of Plasma Technology Al-Azhar University Cairo Egypt Physics Department Faculty of Science Al-Azhar University Cairo Egypt

Effects of addition of H2 gas in air DB discharge on its optical and electrical characteristics have been studied. Optical emission spectroscopy is used to investigate the effect of hydrogen admixing on the emission intensity of the nitrogen second positive systems (300 - 420 nm) and the relative population density of states. An obvious decaying of the emission intensity of the nitrogen second positive bands with the introduction of H2 has been observed. It has been concluded that quenching of the nitrogen excited state is the responsible reason of this decaying. Mechanisms of excitation and ionization processes of nitrogen molecules in this mixture have been studied. Processes which are responsible for the decaying of the population density of have been reported. Addition of H2 to air improves the electrical characteristics of the DB discharge. An abrupt increasing in the electron density, reached about thirty fold at H2 flow rate of 3 L/min, as a result of increasing the ionization processes has been reported. The breakdown voltage of the discharge decreased from 1.87 kV to about 1.25 kV by the addition of H2 at flow rate of 3 L/min.

关键词： Nitrogen Second Positive DBD H2 Addition Intensity Decaying

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