检索结果-南通市图书馆

Stimbiotic supplementation modulated intestinal inflammatory response and improved broilers performance in an experimentally-induced necrotic enteritis infection model

引用

Journal of Animal Science and Biotechnology 2023年第1期14卷 322-338页

作者： Ji Hwan Lee Byongkon Lee Xavière Rousseau Gilson A.Gomes Han Jin Oh Yong Ju kim Se Yeon Chang Jae Woo An Young Bin Go dong Cheol Song Hyun Ah Cho Jin Ho Cho Department of Animal Science Chungbuk National UniversityCheongju 28644South Korea. Cherrybro Co. Ltd.Jincheon‑Gun 27820South Korea. AB Vista MarlboroughWiltshireUK.

Background:Two experiments were conducted to establish an optimal NE challenge model and evaluate the efficacy of stimbiotic(STB)supplementation in necrotic enteritis(NE)challenged *** Exp.1,a total of 120 Arbor Acres(AA)broilers(45.0±0.21 g)were randomly assigned to 6 treatments in a 3×2 factorial *** treatments included non-challenge(0),×10 the recommended dose(×10)or×20 the recommended dose(×20)by the *** perfringens(CP)treatments were non-challenge(No)or 3 mL of 2.2×10^(7)CFU CP challenge(Yes).In Exp.2,a total of 72 AA broilers(40.17±0.27 g)were randomly assigned to 6 treatments in a 3×2 factorial *** treatments included non-additive(CON),100 mg/kg STB(STB)and 100 mg/kg STB on top of a typical commercial blend including an essential oil,probiotics,and enzyme(CB).Challenge treatments included non-NE challenge(No)and NE challenge(Yes)as established in ***:In Exp.1,CP and vaccine challenge decreased(Pdose of vaccines coupled with 3 mL of 2.2×10^(7)CFU CP resulted in(Pdotoxin in the serum compared with the non-NE challenged *** supplementation of STB and CB in diets enhanced(P<0.05)growth performance,intestinal microbiota,and blood profiles by stimulating ileal morphology(VH and VH:CD)and propionate production in the cecum,and there were no differences in measured variables between STB and CB supplemented

关键词： Broiler chicken Clostridium perfringens Necrotic enteritis Xylanse Xylooligosaccharide

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hematologic diseases: High risk of Clostridium difficile associated diarrhea

引用

World Journal of Gastroenterology 2014年第21期20卷 6602-6607页

作者： Tae-Geun Gweon Myung-Gyu Choi Myong Ki Baeg Chul-Hyun Lim Jae Myung Park In Seok Lee Sang Woo kim dong-gun Lee Yeon Joon Park Jong Wook Lee Division of Gastroenterology Department of Internal MedicineSeoul St Mary’s hospitalThe Catholic University of KoreaCollege of MedicineSeoul 137-701South Korea Division of Infectious Diseases Department of Internal MedicineSeoul St Mary’s hospitalThe Catholic University of KoreaCollege of MedicineSeoul 137-701South Korea Department of Laboratory Medicine Seoul St Mary’s hospitalThe Catholic University of KoreaCollege of MedicineSeoul 137-701South Korea Division of Hematologic Diseases Department of Internal MedicineSeoul St Mary’s hospitalThe Catholic University of KoreaCollege of MedicineSeoul 137-701South Korea

AIM:To investigate the incidence and clinical outcome of Clostridium difficile(***)associated diarrhea(CDAD)in patients with hematologic ***:We retrospectively reviewed the medical records of patients who underwent *** testing in a tertiary hospital in *** incidence and risk factors for CDAD and its clinical course including recurrence and mortality were assessed in patients with hematologic disease and compared with those in patients with nonhematologic ***:About 320 patients were diagnosed with CDAD(144 patients with hematologic disease;176with nonhematologic disease).The incidence of CDAD in patients with hematologic disease was estimated to be 36.7 cases/10000 patient hospital days,which was higher than the 5.4 cases/10000 patient hospital days in patients with nonhematologic *** of CDAD was more frequent in patients with hematologic disease compared to those with nonhematologic disease(18.8%vs 8.5%,P<0.01),which was associated with higher re-use of causative antibiotics for *** due to CDAD did not differ between the two *** analysis showed that intravenous immunoglobulin was the only significant factor associated with a lower rate of recurrence of CDAD in patients with hematologic ***:The incidence and recurrence of CDAD was higher in patients with hematologic disease than in those with nonhematologic disease.

关键词： Clostridium difficile associated diarrhea Incidenc

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The effects of feeding rate in juvenile olive flounder,Paralichthys olivaceus,fed commercial diet at the low temperature season

The effects of feeding rate in juvenile olive flounder,Paral...

引用

The 14th International Symposium on Fish Nutrition & Feeding

作者： Namyong Hwang Jun-Ho Lee Seunghyung Lee Young Chul kim Jun-Young Bae Okorie E.Okorie Mahmoud Mohseni gun Hyun Park Sungchul C.Bai Dept.of Aquaculture / Feeds and Foods Nutritional Research Center(FFNRC)Pukyong Nat’l University

Production of olive flounder(Paralichthys olivaceus) ranked the top among the Korean mariculture finfish *** of Korean aqua-farmers rely on farm-made raw fish-based diets (moist pellets,MP).They believe that moist pellets give better growth than do extruded pellets (EP).However,the use of moist pellets is being discouraged due to the water pollution resulting from such a practice and shortage of resources for making *** government also recommends the use of extruded diets in aquaculture and encourages the development of environmentally friendly diet with optimum feeding *** particular interest in the feeding practice is the optimum feeding rate,which has been found to be influenced by several factors among which is the rearing water *** temperatures in the winter season cause stress;reduce resistance to disease;and decrease feed intake and *** ongoing study is conducted to investigated the effects of feeding rates in juvenile olive flounder fed commercial diet(extrude pellet) at the low temperature season(below 15℃).Three replicated groups of fish (initial weight 5.3±0.22g) are fed commercial diet at the feeding rates of 0,0.5,1,1.5 and 2% body weight(BW)/day and *** feeding trial is conducted by using a semi-recirculating system with eighteen 30-L aquaria receiving filtered seawater from a center *** duration of the trial is four *** effects of feeding rates on growth performance,body composition and histology will be discussed later

关键词： Feeding rate olive flounder low temperature winter season

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Chrysanthemum indicum ethanol extract attenuates hepatic stellate cell activation in vitro and thioacetamide-induced hepatofibrosis in rats

引用

Asian Pacific Journal of Tropical Biomedicine 2021年第11期11卷 500-509页

作者： Yun-Jin Chae Sushruta Koppula Myong-Ki kim Tony Yoon Mindong Song Department of Applied Life Science Graduate School of Konkuk University268 Chungwon-daeroChungju-siChungbuk27478Republic of Korea Department of Biotechnology College of Biomedical and Health SciencesKonkuk University268 Chungwon-daeroChungju-siChungbuk27478Republic of Korea Research Institute and College of Biomedical&Health Science Konkuk University268 Chungwon-daeroChungju-siChungbuk27478Republic of Korea Scholar Foxtrot Co. LTD501SinGwan-dong 5FJongam-ro 36-gilSeongbuk-guSeoul02796Republic of Korea Department of Food Science and Engineering Seowon UniversityCheongjuChungbuk 28674Republic of Korea Food One Corp 127Sincheoksandan 5-roDeoksan-eupJincheon-gunChungbuk 27850Republic of Korea

Objective:To investigate the antifibrotic effects of Chrysanthemum indicum ethanol extract(CIEE)against activated hepatic stellate cells(HSC)and thioacetamide(TAA)-induced hepatofibrosis in ***:Cell viability and proliferation of HSC-T6 cells were measured using MTT *** HSCs were used to study ***(200 mg/kg)was used to induced hepatic fibrosis in ***(100 and 500 mg/kg)and silymarin(50 mg/kg)were administered *** functions including alanine transaminase,aspartate transaminase,glutathione,and hydroxyproline levels were measured using commercial *** sections and fibrotic biomarker expression were measured using hematoxylin and eosin staining and real-time polymerase chain ***:In vitro study revealed that CIEE(0.1,0.25,and 0.5 mg/mL)inhibited the proliferation of activated HSCs exposed to transforming growth factor(TGF)-β and restored the activated primary HSC *** in vivo studies,TAA-induced increase in liver/body weight ratio(5.46±0.26)was significantly reduced(4.13±0.22)by CIEE(P<0.05 at 500 mg/kg).CIEE(100 and 500 mg/kg)improved the liver functions by significantly attenuating changes in alanine transaminase,aspartate transaminase,glutathione,and hydroxyproline levels(P<0.05).Further,CIEE(100 and 500 mg/kg)ameliorated the histological changes in liver tissue and TGF-β expression significantly(P<0.05)in TAA-induced ***:CIEE significantly protects against TAA-induced liver damage in rats and can be used in the treatment of liver fibrosis.

关键词： Chrysanthemum indicum Fibrosis Hepatoprotective Hydroxyproline Thioacetamide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

来自一项艾日布林联合吉西他滨对比紫杉醇联合吉西他滨作为HER2阴性转移性乳腺癌的一线化疗的Ⅱ期、多中心、随机试验的包含神经病变相关量表的生活质量结果：韩国癌症研究组试验(KCSG BR13-11)

引用

癌症 2019年第8期38卷 368-376页

作者： Ji‑Yeon kim Seri Park Seock‑Ah Im Sung‑Bae kim Joohyuk Sohn Keun Seok Lee Yee Soo Chae Ki Hyeong Lee Jee Hyun kim Young‑Hyuck Im Tae‑Yong kim Kyung‑Hun Lee Jin‑Hee Ahn gun Min kim In Hae Park Soo Jung Lee Hye Sook Han Se Hyun kim Kyung Hae Jung Yeon Hee Park Korean Cancer Study Group Division of Hematology‑Oncology Department of MedicineSamsung Medical CenterSungkyunkwan University School of Medicine81 Irwon‑roGangnam‑guSeoul 06351South Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and TechnologySungkyunkwan UniversitySeoul 06351South Korea Department of Internal Medicine Seoul National University HospitalCancer Research InstituteCollege of MedicineSeoul National UniversitySeoul 03080South Korea Department of Oncology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Division of Medical Oncology Department of Internal MedicineYonsei University College of MedicineSeoul 03722South Korea Center for Breast Cancer National Cancer CenterGoyang 10408South Korea Department of Internal Medicine Kyungpook National University HospitalDaegu 41944South Korea Deparment of Internal Medicine Chungbuk National University HospitalCheongju 28644South Korea Department of Internal Medicine Seoul National University Bundang HospitalSeoul National University College of MedicineSeongnam 13620South Korea 不详

背景与目的一项比较艾日布林联合吉西他滨(eribulin plus gemcitabine,EG)或紫杉醇联合吉西他滨(paclitaxel plus gemcitabine,PG)作为转移性乳腺癌(metastatic breast cancer,MBC)患者一线化疗方案的II期临床试验发现,EG方案的神经毒性较低,但疗效与PG方案相似。在本研究中,我们分析了该临床实验中的癌症患者生命质量测评量表–紫杉烷(functional assessment of cancer therapy-taxane,FACT-Taxane)问卷评分以确定他们的生活质量(quality of life,QoL)。方法使用韩国版的FACT-Taxane问卷评估QoL。在评估基线之后,前12个疗程中每2个疗程评估1次QoL,之后每3个疗程评估1次QoL。使用线性混合模型评估EG组和PG组QoL的差异。结果在118例入组患者中,117例在基线时回复了FACT-Taxane问卷,PG组中有1例患者没有回复。EG组和PG组之间的基线QoL评分没有差异。在治疗期间,除了第11个疗程外,在第2–13个化疗疗程后,PG组紫杉烷亚量表评分显著高于EG组(均P<0.05)。神经病变特异性分析显示PG组患者的神经病症状比EG组患者更早出现且更严重(P<0.001)。结论在我们的QoL分析中,与PG方案相比,EG方案延迟并减少神经病变的发生。因此,艾日布林是MBC一线化疗药物紫杉醇的合理替代品。

关键词：转移性乳腺癌艾日布林紫杉醇神经病生活质量癌症患者生命质量测评量表–紫杉烷问卷

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Magnifying endoscopy for the diagnosis of specialized intestinal metaplasia in short-segment Barrett's esophagus

引用

World Journal of Gastroenterology 2013年第41期19卷 7089-7096页

作者： Nam Seok Ham Jae Young Jang Sung Woo Ryu Ji Hye kim Eui Ju Park Woong Cheul Lee Kwang Yeun Shim Soung Won Jeong Hyun gun kim Tae Hee Lee Sung Ran Jeon Jun Hyung Cho Joo Young Cho So Young Jin Ji Sung Lee Institution for Digestive Research Digestive Disease CenterDepartment of Internal MedicineSoonchunhyang University HospitalSeoul 140-743South Korea Department of Pathology Soonchunhyang University HospitalSeoul 140-743South Korea Biostatistical Consulting Unit Soonchunhyang University HospitalSeoul 140-743South Korea

AIM:To determine whether magnified observation of short-segment Barrett’s esophagus(BE)is useful for the detection of specialized intestinal metaplasia(SIM).METHODS:Thirty patients with suspected short-segment BE underwent magnifying endoscopy up to×*** magnified images were analyzed with respect to their pit-patterns,which were simultaneously classified into five epithelial types[Ⅰ(small round),Ⅱ(straight),Ⅲ(long oval),Ⅳ(tubular),Ⅴ(villous)]by Endo’s ***,a 0.5%solution of methylene blue(MB)was sprayed over columnar *** patterns of the magnified image and MB staining were *** were obtained from the regions previously observed by magnifying endoscopy and MB ***:Three of five patients with a typeⅤ(villous)epithelial pattern had SIM,whereas 21 patients with a non-typeⅤepithelial patterns did not have *** sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of pit-patterns in detecting SIM were 100%,91.3%,92.3%,60%and100%,respectively(P=0.004).Three of the 12 patients with positive MB staining had SIM,whereas 14patients with negative MB staining did not have *** sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of MB staining in detecting SIM were 100%,60.9%,65.4%,25%and100%,respectively(P=0.085).The specificity and accuracy of pit-pattern evaluation were significantly superior compared with MB staining for detecting SIM by comparison with the exact McNemar’s test(P=0.0391).CONCLUSION:The magnified observation of a shortsegment BE according to the mucosal pattern and its classification can be predictive of SIM.

关键词： Short-segment Barrett’s esophagus Magnifying endoscopy Methylene blue chromoendoscopy Specialized intestinal metaplasia Dysplasia Esophageal adenocarcinoma Diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of tamsulosin on ejaculatory function in BPH/LUTS

引用

Asian Journal of Andrology 2011年第6期13卷 846-850页

作者： Sang Hoon Song Hwancheol Son Kwang Taek kim Sae Woong kim Du Geon Moon Ki Hak Moon Kwangsung Park Jong Kwan Park Sung-Won Lee Jae Seog Hyun Nam Cheol Park Jeungpyung Health Center Jeungpyung-gun Chungbuk 368-900 Korea Department of Urology Seoul Metropolitan Boramae Hospital Seoul 156-707 Korea Aerospace Medical Center Cheongwon Chungbuk 363-840 Korea Catholic University of Korea College of Medicine Seoul 137-701 Korea Korea University College of Medicine Seoul 152-703 Korea Department of Urology Yeungnam University College of Medicine Daegu 705-717 Korea Department of Urology Chonnam National University Medical School Gwangju 501-757 Korea Department of Urology Medical School and Institute for Medical Sciences Chonbuk National University Chonbuk 561-712 Korea Research Institute of Clinical Medicine and CTC for Medical Device of Chonbuk National University Hospital Chonbuk 561-712 Korea Samsung Medical Center Sungkyunkwan University School of Medicine Seoul 135-710 Korea Gyeongsang National University Gyeongnam 660-702 Korea pusan National University College of Medicine Pusan 602-739 Korea

This study was undertaken to determine the impact on ejaculatory function of tamsulosin （0.2 mg） given once daily （OD） for 12 weeks and to identify risk factors for ejaculatory dysfunction in patients undergoing this treatment. Males with an International Prostatic Symptom Score （IPSS） ≥ 8 were enrolled in this study. All participants completed questionnaires, including the IPSS and the Male Sexual Health Questionnaire （MSHQ）, and serum prostate-specific antigen, transrectal ultrasound and uroflowmetry with post-void residual were measured. After initiating 0.2 mg OD tamsulosin, patients were re-evaluated on the fourth and twelfth weeks of medication. The chi-squared test, the independent t-test and one-way ANOVA were used to compare means. Binary logistic regression analysis was used to calculate the odds ratio for all risk factors. A total of 177 men constituted the study cohort. No significant difference was observed between baseline and follow-up for the erectile function, ejaculatory function, satisfaction, sexual activity and desire domains （EFD, EjFD, SDA and ADD） or for erectile or ejaculatory bother mean scores. After 12 weeks, the overall incidence of ejaculatory dysfunction （EjD） was 13.4%. Incidences of the seven different types of EjD （decreased frequency, delay, dryness, decreased strength/force, decreased volume, decreased pleasure and pain at ejaculation） were 2.4%, 3.1%, 3.9%, 3.9%, 6.3%, 7.1% and 3.1%, respectively. Baseline EjFD scores were higher for I PSS responders than for non-responders （26.09 vs. 24.06, P=0.03）. An EjFD score reduction was more frequent in IPSS responders. The incidence of EjD was small, but not negligible and was more frequent in patients with less lower urinary tract symptoms, a smaller prostate, higher baseline MSHQ totals and higher EjFD scores.

关键词： alpha-1 adrenergic receptors benign prostatic hyperplasia ejaculation lower urinary tract symptom Male Sexual HealthQuestionnaire prostatic hyperplasia tamsulosin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于体验营销的生活家电企业下游供应链管理研究

引用

物流技术 2012年第9期31卷 332-335页

作者：申光龙金洪雨杨静李城根南开大学商学院天津300071

随着生活水平的提高,消费者在购买商品时,越来越多注重产品和服务所带来体验和感受。基于体验营销的企业下游供应链管理,从消费者出发,通过创设体验营销平台,传递品牌信息,进而为企业创造利润。首先解释了体验营销,之后引入了企业下游... 详细信息

随着生活水平的提高,消费者在购买商品时,越来越多注重产品和服务所带来体验和感受。基于体验营销的企业下游供应链管理,从消费者出发,通过创设体验营销平台,传递品牌信息,进而为企业创造利润。首先解释了体验营销,之后引入了企业下游供应链管理模式,最后详细阐述了在生活家电企业下游供应链管理如何运用体验营销来创造企业价值。

关键词：体验营销生活家电企业下游供应链管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

互动式整合营销传播在供应链管理中的应用模式研究

引用

物流技术 2012年第7期31卷 304-308页

作者：申光龙杨静金洪雨李城根南开大学商学院天津300071

基于互动媒体、数据库及利害关系管理的互动式整合营销传播(Interactive IMC)已经成为非营利组织创造价值、获得资源的重要战略手段。在阐述互动式营销传播的基础上,引入了供应链的价值模式,最后详细分析了互动式整合营销在供应链管理... 详细信息

基于互动媒体、数据库及利害关系管理的互动式整合营销传播(Interactive IMC)已经成为非营利组织创造价值、获得资源的重要战略手段。在阐述互动式营销传播的基础上,引入了供应链的价值模式,最后详细分析了互动式整合营销在供应链管理中的运用。

关键词：互动式整合营销传播互动媒体:数据库管理供应链管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

铝合金与高强钢摩擦塞铆焊接头连接性能

引用

焊接学报 2021年第11期42卷 8-13,I0001页

作者： Lyu Shuqiang kim Jihoon Cho Haeyong Department of Mechanical Engineering Chungbuk National UniversityChungbuk361-763Korea Sunil Dyfas Co. Ltd.Jincheon-GunChungbuk365-830Korea

为了解决铝合金与高强钢材料之间连接困难的问题,保证铝合金与高强钢之间的连接质量,采用摩擦塞铆焊工艺实现了6061-T6铝合金和DP1470高强钢的连接,并通过对接头宏观形貌和微观组织特征的观察、接头力学性能的测试以及接头失效形式的对... 详细信息

为了解决铝合金与高强钢材料之间连接困难的问题,保证铝合金与高强钢之间的连接质量,采用摩擦塞铆焊工艺实现了6061-T6铝合金和DP1470高强钢的连接,并通过对接头宏观形貌和微观组织特征的观察、接头力学性能的测试以及接头失效形式的对比,研究了摩擦塞铆焊所获接头连接性能的变化规律.结果表明,转速是影响焊接质量的重要因素.在焊接试验过程中,转速控制范围为5 000~8 000 r/min,接头的抗拉强度随转速的增加先升高后降低,当转速达到7 000 r/min时,接头所承受的剪切载荷最大,可以达到6.3 kN,此时得到的接头表面平整,无明显孔洞、裂纹等缺陷.铝合金板材在接头处发生断裂失效时,接头所能承受载荷相对较大,焊接质量较高.因此,铝合金和高强钢能够通过摩擦塞铆焊工艺实现高质量连接.

关键词：铝合金高强钢摩擦塞铆焊力学性能失效形式

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：