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Tidal Forecast for Final Closure of Saemangeum Tidal Dike

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China Ocean Engineering 2010年第3期24卷 467-480页

作者： Byung Ho CHOI Jae Wan ha Kwang Oh KO Dae Soo EO Kyeong Ok kim Department of Civil and Environmental Engineering Sungkyunkwan University Hyundai E&C Co. Ltd. Korea Rural Community Corporation Korea Ocean Research & Development Institute

The Saemangeum project includes well-developed tidal flats, two estuaries of the Mankyeong and dongjin rivers, and a chain of small iskands in the outer area off the dike by reclaiming a surface area of 40100 ha. A long sea dike of 30 km has been constructed in the mid-west area of Korea. This paper describes the construction of tidal dikes focusing on the final closure operation performed in April, 2006 employing intermediate technology. Predictive modelling was also carried out to predict the real-time flow fields during the gradual closure operation of the final stage.

关键词： mathematical modelling dams barrages & reservoirs hydraulics & hydrodynamics sea defence

Power management unit chip design for automobile active-matrix organic light-emitting diode display module

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Journal of Central South University 2009年第4期16卷 621-628页

作者： kim J H PARK J H kim J H CAO T V LEE T Y BAN H J YANG K kim H G ha P B kim Y H Department of Electronic Engineering Changwon National University 9 Sarim-Dong Changwon 641-773 Korea Denso PS Electronics Corporation 47 Seongsan-Dong Changwon 641-315 Korea

A power management unit （PMU） chip supplying dual panel supply voltage, which has a low electro-magnetic interference （EMI） characteristic and is favorable for miniaturization, is designed. A two-phase charge pump circuit using external pumping capacitor increases its pumping current and works out the charge-loss problem by using bulk-potential biasing circuit. A low-power start-up circuit is also proposed to reduce the power consumption of the band-gap reference voltage generator. And the ring oscillator used in the ELVSS power circuit is designed with logic devices by supplying the logic power supply to reduce the layout area. The PMU chip is designed with MagnaChip＇s 0.25 μ high-voltage process. The driving currents of ELVDD and ELVSS are more than 50 mA when a SPICE simulation is done.

关键词： DC-DC converter AMOLED charge pumping power management unit (PMU) dual panel supply voltage

Ultrasonographic identification of lateral femoral cutaneous nerve anatomical variation in persistent meralgia paresthetica:A case report

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World Journal of Clinical Cases 2023年第31期11卷 7699-7705页

作者： Hyeong-Woo Park Kyung-Suk Ji Jun-Hyung kim Li-Na kim Kang-Wook ha Department of Physical Medicine and Rehabilitation Sahmyook Medical CenterSeoul 02500South Korea Department of Obstetrics and Gynecology Sahmyook Medical CenterSeoul 02500South Korea

BACKGROUND Meralgia paresthetica(MP)is an entrapment mononeuropathy of the lateral femoral cutaneous nerve(LFCN).Although structural abnormalities in nerve tissues can be confirmed using ultrasonography,this is not routinely *** SUMMARY Herein,we present the case of a 52-year-old woman who developed MP after laparoscopic gynecological *** patient was referred to our clinic from an obstetrics and gynecology clinic with symptoms of numbness and a tingling sensation in the left anterolateral thigh,which developed after surgery performed 5 mo *** were performed to assess the disease status and determine the underlying *** examination revealed an anatomical variation,where the left LFCN was entrapped within the inguinal *** case suggests that performing ultrasonographic examination before and after surgery in the lithotomy position could help prevent *** This case demonstrates the value of ultrasonography in detecting anatomical variation and diagnosing persistent *** should be considered an adjunct to electromyography for optimal MP ***,this case would help other clinicians determine patient prognosis and decide on targeted treatment strategies.

关键词： Lateral femoral cutaneous nerve Anatomical variation Meralgia paresthetica Lithotomy position Ultrasonography Case report

Study on the Relationship between Mental Health Literacy and Psychological Symptoms of University Students: Mediating Effect of Grit

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International Journal of Mental Health Promotion 2023年第7期25卷 813-821页

作者： Yeo-Won Jeong Jung-ha kim Hyun-Kyeong Park Department of Nursing College of Nursing Dongguk UniversityGyeongju-si38066Korea Aeromedical Center of Korean Air Seoul07505Korea Department of Nursing Graduate SchoolDongguk UniversityGyeongju-si38066Korea

Background:The occurrence of mental health symptoms is higher in individuals aged between 18 and 24 years than in other age *** health literacy is derived from health literacy,and focuses on the knowledge,attitudes,and competencies that individuals need to acquire to manage their own health *** mental health literacy is associated with poorer mental *** is also a known protective factor against mental *** a heightened focus on mental health literacy and grit as important factors for decreasing mental health symptoms,knowledge of the effect of mental health literacy and grit on mental health symptoms is very *** study aimed to evaluate the relationship between mental health literacy and psychological symptoms and the mediating effect of grit on these ***:This cross-sectional descriptive study used survey data from 178 university students in *** were collected between March and May *** SPSS PROCESS macro(Model 4)was used to analyze the ***:Mental health literacy was not directly associated with psychological ***,an indirect pathway was observed between mental health literacy,depression,and anxiety,through ***:Mental health literacy affects psychological symptoms through ***,to improve the mental health of university students,it is necessary to develop programs that increase mental health literacy and grit.

关键词： Depression anxiety psychological stress health literacy mental health students

Design of 256 bit single-poly MTP memory based on BCD process

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Journal of Central South University 2012年第12期19卷 3460-3467页

作者： kim Kwang-il kim Min-sung PARK Young-bae PARK Mu-hun ha Pan-bong kim Young-hee Department of Electronic Engineering Changwon National University9 Sarim-DongChangwon 641-773Korea

We propose a single-poly MTP （multi-time programmable） cell consisting of one capacitor and two transistors based on MagnaChip＇s BCD process. The area of a unit cell is 37.743 75μm^2. The proposed single-poly MTP cell is erased and programmed by the FN tunnelling scheme. We design a 256 bit MTP memory for PMICs （power management ICs） using the proposed single-poly MTP cells. For small-area designs, we propose a selection circuit between V10V and VSV, and a WL （word-line） driver by simplifying its logic circuit. We reduce the total layout area by using pumped internal node voltages from a seven-stage cross-coupled charge pump for V10V （=10 V） and V5V （=5 V） without any additional charge pumps. The layout size of the designed 256 bit MTP memory is 618.250 μm × 437.425μm.

关键词： multi-time programmable memory PMIC cross-coupled charge pump

Malignant triton tumor in the abdominal wall:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1467-1473页

作者： Ho Jik Yang donghyun kim Won Suk Lee Sang-ha Oh Department of Plastic and Reconstructive Surgery Chungnam National University Sejong HospitalSejong 30099South Korea Department of Plastic and Reconstructive Surgery Chungnam National University HospitalDaejeon 35015South Korea Department of Emergency Eulji University HospitalDaejeon 35233South Korea Department of Plastic and Reconstructive Surgery Chungnam National University College of MedicineDaejeon 35015South Korea

BACKGROUND Malignant triton tumors(MTTs)comprise a subgroup of malignant peripheral nerve sheath tumors(MPNSTs)that exhibits rhabdomyosarcomatous differen-tiation and follow an aggressive *** are primarily located along peripheral *** of MTTs in the abdominal wall have not been *** has a poorer prognosis than classic MPNSTs,and accurate diagnosis necessitates a keen understanding of the clinical history and knowledge of its differential diagnosis *** for MTTs mirrors that for MPNSTs and is predominantly *** SUMMARY A 49-year-old woman presented with a subcutaneous mass in her lower abdo-minal wall and a pre-existing surgical scar that had grown slowly over 3-4 months before the *** had previously undergone radical hysterectomy and concurrent chemo-radiotherapy for cervical cancer approximately 5 years prior to the *** computed tomography(CT)showed a 1.3 cm midline mass in the lower abdomen with infiltration into the rectus abdominis *** was no sign of metastasis(T1N0M0).An incisional biopsy identified sporadic MTT of the lower abdomen.A comprehensive surgical excision with a 3 cm margin inclusive of the peritoneum was ***-quently,the general surgeon utilized an approach akin to the open peritoneal onlay mesh *** patient underwent additional treatment with an excision shaped as a mini-abdominoplasty for the skin *** complications arose,and annual follow-up CTs did not show signs of recurrence or *** An abdominal MTT was efficaciously treated with extensive excision and abdominal wall reconstruction,eliminating the need for postoperative radiotherapy.

关键词： Malignant triton tumor Abdominal wall Surgical excision Reconstruction Case report

Effects of lysophosphatidic acid on human periodontal ligament stem cells from teeth extracted from dental patients

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The Journal of Biomedical Research 2019年第2期33卷 122-130页

作者： Byung Cheol kim Jae-In Song Kyoung-ha So Sang-Hwan Hyun Laboratory of Veterinary Embryology and Biotechnology Veterinary Medical Center and College of Veterinary MedicineChungbuk National University Institute of Stem Cell & Regenerative Medicine Chungbuk National University

Despite their potential applications in future regenerative medicine, periodontal ligament stem cells(PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining sternness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from the bench to the clinic. Lysophosphatidic acid(LPA), which is present in the human body and saliva, is a signaling molecule derived from phospholipids. In this study, we examined the effects of LPA on sternness maintenance in human PDLSCs. Several spindle-shaped and fibroblast-like periodontal ligament stem-like cell lines were established from PDLSC isolation. Among these cell lines, the most morphologically appropriate cell line was characterized. The expression levels of OCT4, NANOG(a stem cell marker), and CD90(a mesenchymal stem cell marker) were high. However, CD73(a negative marker of mesenchymal stem cells) expression was not observed. Notably, immunofluorescence analysis identified the expression of STRO-1, CD146(a mesenchymal stem cell marker), and sex determining region Y-box 2 at the protein level. In addition, lipid droplets were stained by Oil red O after the induction of adipogenesis for 21 days, and mineralized nodules were stained by Alizarin Red S after the induction of osteogenesis for 14 days. Alkaline phosphate staining also demonstrated the occurrence of osteogenesis. In summary, we established a human PDLSC line, which could be applied as a cell source for tissue regeneration in dental patients. However, further studies are needed to determine the detailed effects of LPA on PDLSCs.

关键词： periodontal ligament stem cell lysophosphatidic acid stemness primary cell culture

Design of 32 kbit one-time programmable memory for microcontroller units

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Journal of Central South University 2012年第12期19卷 3475-3483页

作者： JEON Hwang-gon CHOI In-hwa ha Pan-bong kim Young-hee Department of Electronic Engineering Changwon National University9 Sarim-DongChangwon 641-773Korea

A 32 kbit OTP(one-time programmable)memory for MCUs(micro-controller units)used in remote controllers was *** OTP memory is used for program and data *** is required to apply 5.5V to BL(bit-line)and 11V to WL(word-line)for a OTP cell of 0.35μm ETOX(EEPROM tunnel oxide)type by *** use 5V transistors on column data paths to reduce the area of column data paths since they require small *** addition,we secure device reliability by using HV(high-voltage)transistors in the WL ***,we change from a static logic to a dynamic logic used for the WL driver in the core ***,we optimize the WD(write data)switch ***,we can implement them with a small-area *** addition,we implement the address predecoder with a small-area logic *** area of the designed 32 kbit OTP with 5V and HV devices is 674.725μm×258.75μm(=0.1745mm2)and is 56.3% smaller than that using 3.3V devices.

关键词： one-time programmable memory micro controller unit EEPROM tunnel oxide small-area

RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts

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Bone Research 2024年第2期12卷 407-420页

作者： Minhee kim Jin Hee Park Miyeon Go Nawon Lee Jeongin Seo hana Lee doyong kim Hyunil ha Taesoo kim Myeong Seon Jeong Suree kim Taesoo kim han Sung kim dongmin Kang Hyunbo Shim Soo Young Lee Department of Life Science Ewha Womans UniversitySeoul 03760South Korea The Research Center for Cellular Homeostasis Ewha Womans UniversitySeoul 03760South Korea Department of Biomedical Engineering Yonsei UniversityWonju 26493South Korea KM Convergence Research Division Korea Institute of Oriental MedicineDaejeon 34054South Korea Chuncheon Center Korea Basic Science InstituteChuncheon 24341South Korea Fluorescence Core Imaging Center and Bioimaging Data Curation Center Ewha Womans UniversitySeoul 03760South Korea Multitasking Macrophage Research Center Ewha Womans UniversitySeoul 03760South Korea

Mature osteoclasts degrade bone matrix by exocytosis of active proteases from secretory lysosomes through a ruffled ***,the molecular mechanisms underlying lysosomal trafficking and secretion in osteoclasts remain largely ***,we show with GeneChip analysis that RUN and FYVE domain-containing protein 4(RUFY4)is strongly upregulated during *** lacking Rufy4 exhibited a high trabecular bone mass phenotype with abnormalities in osteoclast function in ***,deleting Rufy4 did not affect osteoclast differentiation,but inhibited bone-resorbing activity due to disruption in the acidic maturation of secondary lysosomes,their trafficking to the membrane,and their secretion of cathepsin K into the extracellular ***,RUFY4 promotes late endosome-lysosome fusion by acting as an adaptor protein between Rab7 on late endosomes and LAMP2 on primary ***,Rufy4-deficient mice were highly protected from lipopolysaccharide-and ovariectomy-induced bone ***,RUFY4 plays as a new regulator in osteoclast activity by mediating endo-lysosomal trafficking and have a potential to be specific target for therapies against bone-loss diseases such as osteoporosis.

关键词： osteoclast inhibited traffic